Pain as a risk factor for substance use: a qualitative study of people who use drugs in British Columbia, Canada

Pauline Voon, Alissa M Greer, Ashraf Amlani, Cheri Newman, Charlene Burmeister, Jane A Buxton, Pauline Voon, Alissa M Greer, Ashraf Amlani, Cheri Newman, Charlene Burmeister, Jane A Buxton

Abstract

Background: People who use drugs have a significantly higher prevalence of chronic non-cancer pain compared to the general population, yet little is known about how various policy, economic, physical, and social environments may serve as risk or protective factors in the context of concurrent pain and substance use. Therefore, this study sought to explore perspectives, risks, and harms associated with pain among people who use drugs.

Methods: Thirteen focus group interviews were held across British Columbia, Canada, from July to September 2015. In total, 83 people who had lived experience with substance use participated in the study. Using an interpretive description approach, themes were conceptualized according to the Rhodes' Risk Environment and patient-centered care frameworks.

Results: Participants described how their experiences with inadequately managed pain in various policy, economic, physical, and social environments reinforced marginalization, such as restrictive policies, economic vulnerability, lack of access to socio-physical support systems, stigma from health professionals, and denial of pain medication leading to risky self-medication. Principles of patient-centered care were often not upheld, from a lack of recognition of patients as experts in understanding their unique pain needs and experiences, to an absence of shared power and decision-making, which often resulted in distrust of the patient-provider relationship.

Conclusions: Various risk environments and non-patient-centered interactions may contribute to an array of health and social harms in the context of inadequately managed pain among people who use drugs.

Keywords: Harm reduction; Methadone; Pain; Patient-centered care; Risk environment; Self-management.

Conflict of interest statement

Ethics approval and consent to participate

All focus group participants provided informed consent and received food, transportation, and a $20 stipend. This study received ethical approval by the University of British Columbia Research Ethics Board (H15-00126).

Consent for publication

Not applicable.

Competing interests

The authors declare that they have no competing interests.

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

References

    1. Institute of Medicine Report from the Committee on Advancing Pain Research, Care, and Education . Relieving pain in America, a blueprint for transforming prevention, care, education and research. America: The National Academies Press; 2011.
    1. Voon P, Karamouzian M, Kerr T. Chronic pain and opioid misuse: a review of reviews. Subst Abuse Treat Prev Policy. 2017;12:36. doi: 10.1186/s13011-017-0120-7.
    1. Breitbart W, Rosenfeld B, Passik S, Kaim M, Funesti-Esch J, Stein K. A comparison of pain report and adequacy of analgesic therapy in ambulatory AIDS patients with and without a history of substance abuse. Pain. 1997;72:235–243. doi: 10.1016/S0304-3959(97)00039-0.
    1. Berg KM, Arnsten JH, Sacajiu G, Karasz A. Providers’ experiences treating chronic pain among opioid-dependent drug users. J Gen Intern Med. 2009;24:482–488. doi: 10.1007/s11606-009-0908-x.
    1. Baldacchino A, Gilchrist G, Fleming R, Bannister J. Guilty until proven innocent: a qualitative study of the management of chronic non-cancer pain among patients with a history of substance abuse. Addict Behav. 2010;35:270–272. doi: 10.1016/j.addbeh.2009.10.008.
    1. Beauchamp GA, Winstanley EL, Ryan SA, Lyons MS. Moving beyond misuse and diversion: the urgent need to consider the role of iatrogenic addiction in the current opioid epidemic. Am J Public Health. 2014;104:2023–2029. doi: 10.2105/AJPH.2014.302147.
    1. Dowell D, Haegerich TM, Chou R. CDC guideline for prescribing opioids for chronic pain—United States, 2016. JAMA. 2016;315:1624–1645. doi: 10.1001/jama.2016.1464.
    1. McCreaddie M, Lyons I, Watt D, Ewing E, Croft J, Smith M, Tocher J. Routines and rituals: a grounded theory of the pain management of drug users in acute care settings. J Clin Nurs. 2010;19:2730–2740. doi: 10.1111/j.1365-2702.2010.03284.x.
    1. Merrill JO, Rhodes LA, Deyo RA, Marlatt GA, Bradley KA. Mutual mistrust in the medical care of drug users: the keys to the “narc” cabinet. J Gen Intern Med. 2002;17:327–333.
    1. Stewart M, Brown JB, Donner A, McWhinney IR, Oates J, Weston WW, Jordan J. The impact of patient-centered care on outcomes. J Fam Pract. 2000;49:796–804.
    1. McNeil R, Kerr T, Pauly B, Wood E, Small W. Advancing patient-centered care for structurally vulnerable drug-using populations: a qualitative study of the perspectives of people who use drugs regarding the potential integration of harm reduction interventions into hospitals. Addiction. 2016;111:685–694. doi: 10.1111/add.13214.
    1. Rhodes T. Risk environments and drug harms: a social science for harm reduction approach. Int J Drug Policy. 2009;20:193–201. doi: 10.1016/j.drugpo.2008.10.003.
    1. Buxton JA, Newman C. PEEPing into the lives of people who use drugs and understanding how their experiences are shaped by provider attitudes. Ottawa: Official Conference of the Canadian Public Health Association; 2016.
    1. Amlani A, Greer AM, Newman C, Leblanc B, Lampkin H, Lacroix K, Burmeister C, Buxton JA. Public health 2016. Canada: Official Conference of the Canadian Public Health Association Toronto; 2016. Participant, Peer and Peep: engaging people who have used illicit drugs in qualitative research.
    1. Greer AM, Newman C, Burmeister C, Burgess H, Coll M, Choisil P, LeBlanc B, Lacroix K, Lampkin H, Amlani A, Pauly B, Buxton JA. Peer engagement principles and best practices: a guide for BC health authorities and other providers (version 2). Vancouver, BC: BC Centre for Disease Control; 2017. .
    1. Greer AM, Luchenski SA, Amlani AA, Lacroix K, Burmeister C, Buxton JA. Peer engagement in harm reduction strategies and services: a critical case study and evaluation framework from British Columbia, Canada. BMC Public Health. 2016;16:452. doi: 10.1186/s12889-016-3136-4.
    1. Ti L, Tzemis D, Buxton JA. Engaging people who use drugs in policy and program development: a review of the literature. Subst Abuse Treat Prev Policy. 2012;7:47. doi: 10.1186/1747-597X-7-47.
    1. Hunt MR. Strengths and challenges in the use of interpretive description: reflections arising from a study of the moral experience of health professionals in humanitarian work. Qual Health Res. 2009;19:1284–1292. doi: 10.1177/1049732309344612.
    1. Thorne S, Kirkham SR, MacDonald-Emes J. Interpretive description: a noncategorical qualitative alternative for developing nursing knowledge. Res Nurs Health. 1997;20:169–177. doi: 10.1002/(SICI)1098-240X(199704)20:2<169::AID-NUR9>;2-I.
    1. Eyler EC. Chronic and acute pain and pain management for patients in methadone maintenance treatment. Am J Addict. 2013;22:75–83. doi: 10.1111/j.1521-0391.2013.00308.x.
    1. Voon P, Hayashi K, Milloy MJ, Nguyen P, Wood E, Montaner J, Kerr T. Pain among high-risk patients on methadone maintenance treatment. J Pain. 2015;16:887–894. doi: 10.1016/j.jpain.2015.06.003.
    1. Keane H. Categorising methadone: addiction and analgesia. Int J Drug Policy. 2013;24:e18–e24. doi: 10.1016/j.drugpo.2013.05.007.
    1. Peles E, Schreiber S, Gordon J, Adelson M. Significantly higher methadone dose for methadone maintenance treatment (MMT) patients with chronic pain. Pain. 2005;113:340–346. doi: 10.1016/j.pain.2004.11.011.
    1. Eap CB, Buclin T, Baumann P. Interindividual variability of the clinical pharmacokinetics of methadone: implications for the treatment of opioid dependence. Clin Pharmacokinet. 2002;41:1153–1193. doi: 10.2165/00003088-200241140-00003.
    1. Alford DP, Compton P, Samet JH. Acute pain management for patients receiving maintenance methadone or buprenorphine therapy. Ann Intern Med. 2006;144:127–134. doi: 10.7326/0003-4819-144-2-200601170-00010.
    1. Woo J, Bhalerao A, Bawor M, Bhatt M, Dennis B, Mouravska N, Zielinski L, Samaan Z. “Don’t judge a book its cover”: a qualitative study of methadone patients’ experiences of stigma. Subst Abuse. 2017;11:1-12.
    1. Jamison RN, Kauffman J, Katz NP. Characteristics of methadone maintenance patients with chronic pain. J Pain Symptom Manag. 2000;19:53–62. doi: 10.1016/S0885-3924(99)00144-X.
    1. Rosenblum A, Joseph H, Fong C, Kipnis S, Cleland C, Portenoy RK. Prevalence and characteristics of chronic pain among chemically dependent patients in methadone maintenance and residential treatment facilities. JAMA. 2003;289:2370–2378. doi: 10.1001/jama.289.18.2370.
    1. Scimeca MM, Savage SR, Portenoy R, Lowinson J. Treatment of pain in methadone-maintained patients. Mt Sinai J Med. 2000;67:412–422.
    1. BC Centre on Substance Use and BC Ministry of Health: A guideline for the clinical management of opioid use disorder. June 5, 2017. .
    1. Ciccarone D. Fentanyl in the US heroin supply: a rapidly changing risk environment. Int J Drug Policy. 2017;46:107–111. doi: 10.1016/j.drugpo.2017.06.010.
    1. Marshall BDL, Krieger MS, Yedinak JL, Ogera P, Banerjee P, Alexander-Scott NE, Rich JD, Green TC. Epidemiology of fentanyl-involved drug overdose deaths: a geospatial retrospective study in Rhode Island, USA. Int J Drug Policy. 2017;46:130–135. doi: 10.1016/j.drugpo.2017.05.029.
    1. Voon P, Callon C, Nguyen P, Dobrer S, Montaner J, Wood E, Kerr T. Self-management of pain among people who inject drugs in Vancouver. Pain Manag. 2014;4:27–35. doi: 10.2217/pmt.13.62.
    1. Voon P, Callon C, Nguyen P, Dobrer S, Montaner JS, Wood E, Kerr T. Denial of prescription analgesia among people who inject drugs in a Canadian setting. Drug Alcohol Rev. 2015;34:221–228. doi: 10.1111/dar.12226.
    1. Ti L, Voon P, Dobrer S, Montaner J, Wood E, Kerr T. Denial of pain medication by health care providers predicts in-hospital illicit drug use among individuals who use illicit drugs. Pain Res Manag. 2015;20:84–88. doi: 10.1155/2015/868746.
    1. Young AM, Havens JR, Leukefeld CG. Route of administration for illicit prescription opioids: a comparison of rural and urban drug users. Harm Reduct J. 2010;7:24. doi: 10.1186/1477-7517-7-24.
    1. Kitzinger J. Qualitative research. Introducing focus groups. BMJ. 1995;311:299–302. doi: 10.1136/bmj.311.7000.299.
    1. Smithson J. Using and analysing focus groups: limitations and possibilities. Int J Soc Res Methodol. 2000;3:103–119. doi: 10.1080/136455700405172.
    1. Chou R, Turner JA, Devine EB, Hansen RN, Sullivan SD, Blazina I, Dana T, Bougatsos C, Deyo RA. The effectiveness and risks of long-term opioid therapy for chronic pain: a systematic review for a National Institutes of Health Pathways to Prevention Workshop. Ann Intern Med. 2015;162:276–286. doi: 10.7326/M14-2559.
    1. Fink DS, Schleimer JP, Sarvet A, Grover KK, Delcher C, Castillo-Carniglia A, Kim JH, Rivera-Aguirre AE, Henry SG, Martins SS, Cerda M. Association between prescription drug monitoring programs and nonfatal and fatal drug overdoses: a systematic review. Ann Intern Med. 2018;168:783–790. doi: 10.7326/M17-3074.
    1. Bradford AC, Bradford WD, Abraham A, Bagwell Adams G. Association between US state medical cannabis laws and opioid prescribing in the Medicare part D population. JAMA Intern Med. 2018;178:667–672. doi: 10.1001/jamainternmed.2018.0266.
    1. Wen H, Hockenberry JM. association of medical and adult-use marijuana laws with opioid prescribing for Medicaid enrollees. JAMA Intern Med. 2018;178:673–679. doi: 10.1001/jamainternmed.2018.1007.
    1. Katz MH. Opioid prescribing for chronic pain: not for the faint of heart. JAMA Intern Med. 2016;176:599–601. doi: 10.1001/jamainternmed.2016.0664.

Source: PubMed

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