Correction: Zheng, L., et al. PBN11-8, a Cytotoxic Polypeptide Purified from Marine Bacillus, Suppresses Invasion and Migration of Human Hepatocellular Carcinoma Cells by Targeting Focal Adhesion Kinase Pathways. Polymers 2018, 10, 1043
Lanhong Zheng, Xiangjie Zhu, Kangli Yang, Meihong Zhu, Ammad Ahmad Farooqi, Daole Kang, Mi Sun, Yixin Xu, Xiukun Lin, Yingang Feng, Fangfang Liang, Fuming Zhang, Robert J Linhardt, Lanhong Zheng, Xiangjie Zhu, Kangli Yang, Meihong Zhu, Ammad Ahmad Farooqi, Daole Kang, Mi Sun, Yixin Xu, Xiukun Lin, Yingang Feng, Fangfang Liang, Fuming Zhang, Robert J Linhardt
Abstract
The authors wish to make a change to the published paper [...].
Figures
PBN11-8 displays potent cytotoxicity to cancer cells. (a) Cells were treated with certain concentrations of PBN11-8. The cell inhibitory rate was determined by MTT assay as described in the experimental section. The IC50 values were 1.56, 1.80, 1.57 and 1.73 µg/mL for BEL-7402, 786-0, HepG2 and Panc-28 cells, respectively. The IC50 values were 11.79 and 14.72 µg/mL for HK2 and L02 cells, respectively. (b) Cells were cultured in a 96-well plate and treated with 4 µg/mL PBN11-8 for each cell line for 0, 12, 24, and 48 h to study the time dependent analysis. Cell viability was analyzed by MTT assay. (c) The results of the crystal violet adhesion assay in BEL-7402 cells induced by 1, 2, 4 µg/mL of PBN11-8 for 12 h. (d) The results of the crystal violet adhesion assay in BEL-7402 cells induced by 2 µg/mL of PBN11-8 for 12, 24 and 48 h. (e,f) The quantitative evaluations of the crystal violet adhesion assay. The data represent the mean ± SD of three independent experiments. * p < 0.05 vs. control; and ** p < 0.01 vs. control.
References
- Zheng L., Zhu X., Yang K., Zhu M., Farooqi A.A., Kang D., Sun M., Xu Y., Lin X., Feng Y., et al. PBN11-8, a Cytotoxic Polypeptide Purified from Marine Bacillus, Suppresses Invasion and Migration of Human Hepatocel-lular Carcinoma Cells by Targeting Focal Adhesion Kinase Pathways. Polymers. 2018;10:1043. doi: 10.3390/polym10091043.
Source: PubMed