Climatic influences on cardiovascular diseases

Maurizio Giuseppe Abrignani, Alberto Lombardo, Annabella Braschi, Nicolò Renda, Vincenzo Abrignani, Maurizio Giuseppe Abrignani, Alberto Lombardo, Annabella Braschi, Nicolò Renda, Vincenzo Abrignani

Abstract

Classical risk factors only partially account for variations in cardiovascular disease incidence; therefore, also other so far unknown features, among which meteorological factors, may influence heart diseases (mainly coronary heart diseases, but also heart failure, arrhythmias, aortic dissection and stroke) rates. The most studied phenomenon is ambient temperature. The relation between mortality, as well as cardiovascular diseases incidence, and temperature appears graphically as a ''U'' shape. Exposure to cold, heat and heat waves is associated with an increased risk of acute coronary syndromes. Other climatic variables, such as humidity, atmospheric pressure, sunlight hours, wind strength and direction and rain/snow precipitations have been hypothesized as related to fatal and non-fatal cardiovascular diseases incidence. Main limitation of these studies is the unavailability of data on individual exposure to weather parameters. Effects of weather may vary depending on other factors, such as population disease profile and age structure. Climatic stress may increase direct and indirect risks to human health via different, complex pathophysiological pathways and exogenous and endogenous mechanisms. These data have attracted growing interest because of the recent earth's climate change, with consequent increasing ambient temperatures and climatic fluctuations. This review evaluates the evidence base for cardiac health consequences of climate conditions, and it also explores potential further implications.

Keywords: Angina pectoris; Cardiovascular diseases; Climate; Meteorology; Myocardial infarction; Weather.

Conflict of interest statement

Conflict-of-interest statement: All authors have nothing to disclose.

©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.

References

    1. Cold exposure and winter mortality from ischaemic heart disease, cerebrovascular disease, respiratory disease, and all causes in warm and cold regions of Europe. The Eurowinter Group. Lancet. 1997;349:1341–1346.
    1. Gemmell I, McLoone P, Boddy FA, Dickinson GJ, Watt GC. Seasonal variation in mortality in Scotland. Int J Epidemiol. 2000;29:274–279.
    1. Enquselassie F, Dobson AJ, Alexander HM, Steele PL. Seasons, temperature and coronary disease. Int J Epidemiol. 1993;22:632–636.
    1. Curriero FC, Heiner KS, Samet JM, Zeger SL, Strug L, Patz JA. Temperature and mortality in 11 cities of the eastern United States. Am J Epidemiol. 2002;155:80–87.
    1. Aylin P, Morris S, Wakefield J, Grossinho A, Jarup L, Elliott P. Temperature, housing, deprivation and their relationship to excess winter mortality in Great Britain, 1986-1996. Int J Epidemiol. 2001;30:1100–1108.
    1. Yang J, Zhou M, Ou CQ, Yin P, Li M, Tong S, Gasparrini A, Liu X, Li J, Cao L, Wu H, Liu Q. Seasonal variations of temperature-related mortality burden from cardiovascular disease and myocardial infarction in China. Environ Pollut. 2017;224:400–406.
    1. Gómez-Acebo I, Llorca J, Rodríguez-Cundín P, Dierssen-Sotos T. Extreme temperatures and mortality in the North of Spain. Int J Public Health. 2012;57:305–313.
    1. Zafeiratou S, Analitis A, Founda D, Giannakopoulos C, Varotsos KV, Sismanidis P, Keramitsoglou I, Katsouyanni K. Spatial Variability in the Effect of High Ambient Temperature on Mortality: An Analysis at Municipality Level within the Greater Athens Area. Int J Environ Res Public Health. 2019;16
    1. Zeng Y, Gu D, Purser J, Hoenig H, Christakis N. Associations of environmental factors with elderly health and mortality in China. Am J Public Health. 2010;100:298–305.
    1. Chen H, Wang J, Li Q, Yagouti A, Lavigne E, Foty R, Burnett RT, Villeneuve PJ, Cakmak S, Copes R. Assessment of the effect of cold and hot temperatures on mortality in Ontario, Canada: a population-based study. CMAJ Open. 2016;4:E48–E58.
    1. Chung Y, Lim YH, Honda Y, Guo YL, Hashizume M, Bell ML, Chen BY, Kim H. Mortality related to extreme temperature for 15 cities in northeast Asia. Epidemiology. 2015;26:255–262.
    1. Chan EY, Goggins WB, Kim JJ, Griffiths SM. A study of intracity variation of temperature-related mortality and socioeconomic status among the Chinese population in Hong Kong. J Epidemiol Community Health. 2012;66:322–327.
    1. Can G, Şahin Ü, Sayılı U, Dubé M, Kara B, Acar HC, İnan B, Aksu Sayman Ö, Lebel G, Bustinza R, Küçükali H, Güven U, Gosselin P. Excess Mortality in Istanbul during Extreme Heat Waves between 2013 and 2017. Int J Environ Res Public Health. 2019;16
    1. Fu SH, Gasparrini A, Rodriguez PS, Jha P. Mortality attributable to hot and cold ambient temperatures in India: a nationally representative case-crossover study. PLoS Med. 2018;15:e1002619.
    1. Guo Y, Gasparrini A, Armstrong BG, Tawatsupa B, Tobias A, Lavigne E, Coelho MSZS, Pan X, Kim H, Hashizume M, Honda Y, Guo YL, Wu CF, Zanobetti A, Schwartz JD, Bell ML, Scortichini M, Michelozzi P, Punnasiri K, Li S, Tian L, Garcia SDO, Seposo X, Overcenco A, Zeka A, Goodman P, Dang TN, Dung DV, Mayvaneh F, Saldiva PHN, Williams G, Tong S. Heat Wave and Mortality: A Multicountry, Multicommunity Study. Environ Health Perspect. 2017;125:087006.
    1. Oray NC, Oray D, Aksay E, Atilla R, Bayram B. The impact of a heat wave on mortality in the emergency department. Medicine (Baltimore) 2018;97:e13815.
    1. Gómez-Acebo I, Llorca J, Dierssen T. Cold-related mortality due to cardiovascular diseases, respiratory diseases and cancer: a case-crossover study. Public Health. 2013;127:252–258.
    1. Fernández-Raga M, Tomás C, Fraile R. Human mortality seasonality in Castile-León, Spain, between 1980 and 1998: the influence of temperature, pressure and humidity. Int J Biometeorol. 2010;54:379–392.
    1. McMichael AJ, Wilkinson P, Kovats RS, Pattenden S, Hajat S, Armstrong B, Vajanapoom N, Niciu EM, Mahomed H, Kingkeow C, Kosnik M, O'Neill MS, Romieu I, Ramirez-Aguilar M, Barreto ML, Gouveia N, Nikiforov B. International study of temperature, heat and urban mortality: the 'ISOTHURM' project. Int J Epidemiol. 2008;37:1121–1131.
    1. Rabczenko D, Wojtyniak B, Kuchcik M, Szymalski W, Seroka W, Żmudzka E. Association between high temperaturę and mortality of Warsaw inhabitants, 2008-2013. Przegl Epidemiol. 2016;70:629–640.
    1. Bell ML, O'Neill MS, Ranjit N, Borja-Aburto VH, Cifuentes LA, Gouveia NC. Vulnerability to heat-related mortality in Latin America: a case-crossover study in Sao Paulo, Brazil, Santiago, Chile and Mexico City, Mexico. Int J Epidemiol. 2008;37:796–804.
    1. Gasparrini A, Guo Y, Hashizume M, Lavigne E, Tobias A, Zanobetti A, Schwartz JD, Leone M, Michelozzi P, Kan H, Tong S, Honda Y, Kim H, Armstrong BG. Changes in Susceptibility to Heat During the Summer: A Multicountry Analysis. Am J Epidemiol. 2016;183:1027–1036.
    1. Guo Y, Punnasiri K, Tong S. Effects of temperature on mortality in Chiang Mai city, Thailand: a time series study. Environ Health. 2012;11:36.
    1. Oudin Åström D, Schifano P, Asta F, Lallo A, Michelozzi P, Rocklöv J, Forsberg B. The effect of heat waves on mortality in susceptible groups: a cohort study of a mediterranean and a northern European City. Environ Health. 2015;14:30.
    1. Argaud L, Ferry T, Le QH, Marfisi A, Ciorba D, Achache P, Ducluzeau R, Robert D. Short- and long-term outcomes of heatstroke following the 2003 heat wave in Lyon, France. Arch Intern Med. 2007;167:2177–2183.
    1. Analitis A, De' Donato F, Scortichini M, Lanki T, Basagana X, Ballester F, Astrom C, Paldy A, Pascal M, Gasparrini A, Michelozzi P, Katsouyanni K. Synergistic Effects of Ambient Temperature and Air Pollution on Health in Europe: Results from the PHASE Project. Int J Environ Res Public Health. 2018;15
    1. Gasparrini A, Guo Y, Hashizume M, Lavigne E, Zanobetti A, Schwartz J, Tobias A, Tong S, Rocklöv J, Forsberg B, Leone M, De Sario M, Bell ML, Guo YL, Wu CF, Kan H, Yi SM, de Sousa Zanotti Stagliorio Coelho M, Saldiva PH, Honda Y, Kim H, Armstrong B. Mortality risk attributable to high and low ambient temperature: a multicountry observational study. Lancet. 2015;386:369–375.
    1. Linares C, Díaz J. Impact of high temperatures on hospital admissions: comparative analysis with previous studies about mortality (Madrid) Eur J Public Health. 2008;18:317–322.
    1. Rocklöv J, Ebi K, Forsberg B. Mortality related to temperature and persistent extreme temperatures: a study of cause-specific and age-stratified mortality. Occup Environ Med. 2011;68:531–536.
    1. Rocklöv J, Forsberg B, Ebi K, Bellander T. Susceptibility to mortality related to temperature and heat and cold wave duration in the population of Stockholm County, Sweden. Glob Health Action. 2014;7:22737.
    1. Achebak H, Devolder D, Ballester J. Heat-related mortality trends under recent climate warming in Spain: A 36-year observational study. PLoS Med. 2018;15:e1002617.
    1. Ragettli MS, Vicedo-Cabrera AM, Schindler C, Röösli M. Exploring the association between heat and mortality in Switzerland between 1995 and 2013. Environ Res. 2017;158:703–709.
    1. Bobb JF, Peng RD, Bell ML, Dominici F. Heat-related mortality and adaptation to heat in the United States. Environ Health Perspect. 2014;122:811–816.
    1. Xu Y, Dadvand P, Barrera-Gómez J, Sartini C, Marí-Dell'Olmo M, Borrell C, Medina-Ramón M, Sunyer J, Basagaña X. Differences on the effect of heat waves on mortality by sociodemographic and urban landscape characteristics. J Epidemiol Community Health. 2013;67:519–525.
    1. Zhang Y, Li C, Feng R, Zhu Y, Wu K, Tan X, Ma L. The Short-Term Effect of Ambient Temperature on Mortality in Wuhan, China: A Time-Series Study Using a Distributed Lag Non-Linear Model. Int J Environ Res Public Health. 2016;13
    1. Zhu G, Zhu Y, Wang Z, Meng W, Wang X, Feng J, Li J, Xiao Y, Shi F, Wang S. The association between ambient temperature and mortality of the coronavirus disease 2019 (COVID-19) in Wuhan, China: a time-series analysis. BMC Public Health. 2021;21:117.
    1. Marchant B, Ranjadayalan K, Stevenson R, Wilkinson P, Timmis AD. Circadian and seasonal factors in the pathogenesis of acute myocardial infarction: the influence of environmental temperature. Br Heart J. 1993;69:385–387.
    1. Wilkinson P, Pattenden S, Armstrong B, Fletcher A, Kovats RS, Mangtani P, McMichael AJ. Vulnerability to winter mortality in elderly people in Britain: population based study. BMJ. 2004;329:647.
    1. Meal AG, Pringle M, Hammersley V. Time changes in new cases of ischaemic heart disease in general practice. Fam Pract. 2000;17:394–400.
    1. Pell JP, Cobbe SM. Seasonal variations in coronary heart disease. QJM. 1999;92:689–696.
    1. Michelozzi P, Accetta G, De Sario M, D'Ippoliti D, Marino C, Baccini M, Biggeri A, Anderson HR, Katsouyanni K, Ballester F, Bisanti L, Cadum E, Forsberg B, Forastiere F, Goodman PG, Hojs A, Kirchmayer U, Medina S, Paldy A, Schindler C, Sunyer J, Perucci CA PHEWE Collaborative Group. High temperature and hospitalizations for cardiovascular and respiratory causes in 12 European cities. Am J Respir Crit Care Med. 2009;179:383–389.
    1. Tian Z, Li S, Zhang J, Guo Y. The characteristic of heat wave effects on coronary heart disease mortality in Beijing, China: a time series study. PLoS One. 2013;8:e77321.
    1. Crawford VL, McCann M, Stout RW. Changes in seasonal deaths from myocardial infarction. QJM. 2003;96:45–52.
    1. Gyllerup S, Lanke J, Lindholm LH, Schersten B. Cold climate is an important factor in explaining regional differences in coronary mortality even if serum cholesterol and other established risk factors are taken into account. Scott Med J. 1993;38:169–172.
    1. Gerber Y, Jacobsen SJ, Killian JM, Weston SA, Roger VL. Seasonality and daily weather conditions in relation to myocardial infarction and sudden cardiac death in Olmsted County, Minnesota, 1979 to 2002. J Am Coll Cardiol. 2006;48:287–292.
    1. Zhang Y, Peng M, Wang L, Yu C. Association of diurnal temperature range with daily mortality in England and Wales: A nationwide time-series study. Sci Total Environ. 2018;619-620:291–300.
    1. Wang X, Li G, Liu L, Westerdahl D, Jin X, Pan X. Effects of Extreme Temperatures on Cause-Specific Cardiovascular Mortality in China. Int J Environ Res Public Health. 2015;12:16136–16156.
    1. Dilaveris P, Synetos A, Giannopoulos G, Gialafos E, Pantazis A, Stefanadis C. CLimate Impacts on Myocardial infarction deaths in the Athens TErritory: the CLIMATE study. Heart. 2006;92:1747–1751.
    1. Wichmann J, Rosengren A, Sjöberg K, Barregard L, Sallsten G. Association between ambient temperature and acute myocardial infarction hospitalisations in Gothenburg, Sweden: 1985-2010. PLoS One. 2013;8:e62059.
    1. Yin Q, Wang J. The association between consecutive days' heat wave and cardiovascular disease mortality in Beijing, China. BMC Public Health. 2017;17:223.
    1. Chen K, Wolf K, Breitner S, Gasparrini A, Stafoggia M, Samoli E, Andersen ZJ, Bero-Bedada G, Bellander T, Hennig F, Jacquemin B, Pekkanen J, Hampel R, Cyrys J, Peters A, Schneider A UF&HEALTH Study Group. Two-way effect modifications of air pollution and air temperature on total natural and cardiovascular mortality in eight European urban areas. Environ Int. 2018;116:186–196.
    1. Vaneckova P, Bambrick H. Cause-specific hospital admissions on hot days in Sydney, Australia. PLoS One. 2013;8:e55459.
    1. Chan EY, Goggins WB, Yue JS, Lee P. Hospital admissions as a function of temperature, other weather phenomena and pollution levels in an urban setting in China. Bull World Health Organ. 2013;91:576–584.
    1. Goldie J, Sherwood SC, Green D, Alexander L. Temperature and Humidity Effects on Hospital Morbidity in Darwin, Australia. Ann Glob Health. 2015;81:333–341.
    1. van Loenhout JAF, Delbiso TD, Kiriliouk A, Rodriguez-Llanes JM, Segers J, Guha-Sapir D. Heat and emergency room admissions in the Netherlands. BMC Public Health. 2018;18:108.
    1. Mastrangelo G, Hajat S, Fadda E, Buja A, Fedeli U, Spolaore P. Contrasting patterns of hospital admissions and mortality during heat waves: are deaths from circulatory disease a real excess or an artifact? Med Hypotheses. 2006;66:1025–1028.
    1. Tian Y, Liu H, Si Y, Cao Y, Song J, Li M, Wu Y, Wang X, Xiang X, Juan J, Chen L, Wei C, Gao P, Hu Y. Association between temperature variability and daily hospital admissions for cause-specific cardiovascular disease in urban China: A national time-series study. PLoS Med. 2019;16:e1002738.
    1. Ponjoan A, Blanch J, Alves-Cabratosa L, Martí-Lluch R, Comas-Cufí M, Parramon D, Del Mar Garcia-Gil M, Ramos R, Petersen I. Effects of extreme temperatures on cardiovascular emergency hospitalizations in a Mediterranean region: a self-controlled case series study. Environ Health. 2017;16:32.
    1. Ebi KL, Exuzides KA, Lau E, Kelsh M, Barnston A. Weather changes associated with hospitalizations for cardiovascular diseases and stroke in California, 1983-1998. Int J Biometeorol. 2004;49:48–58.
    1. Shiue I, Perkins DR, Bearman N. Relationships of physiologically equivalent temperature and hospital admissions due to I30-I51 other forms of heart disease in Germany in 2009-2011. Environ Sci Pollut Res Int. 2016;23:6343–6352.
    1. Yitshak-Sade M, Bobb JF, Schwartz JD, Kloog I, Zanobetti A. The association between short and long-term exposure to PM2.5 and temperature and hospital admissions in New England and the synergistic effect of the short-term exposures. Sci Total Environ. 2018;639:868–875.
    1. de Miguel-Díez J, Jiménez-García R, López de Andrés A, Hernández-Barrera V, Carrasco-Garrido P, Monreal M, Jiménez D, Jara-Palomares L, Álvaro-Meca A. Analysis of environmental risk factors for pulmonary embolism: A case-crossover study (2001-2013) Eur J Intern Med. 2016;31:55–61.
    1. Bhaskaran K, Hajat S, Haines A, Herrett E, Wilkinson P, Smeeth L. Short term effects of temperature on risk of myocardial infarction in England and Wales: time series regression analysis of the Myocardial Ischaemia National Audit Project (MINAP) registry. BMJ. 2010;341:c3823.
    1. Wolf K, Schneider A, Breitner S, von Klot S, Meisinger C, Cyrys J, Hymer H, Wichmann HE, Peters A Cooperative Health Research in the Region of Augsburg Study Group. Air temperature and the occurrence of myocardial infarction in Augsburg, Germany. Circulation. 2009;120:735–742.
    1. Misailidou M, Pitsavos C, Panagiotakos DB, Chrysohoou C, Stefanadis C. Short-term effects of atmospheric temperature and humidity on morbidity from acute coronary syndromes in free of air pollution rural Greece. Eur J Cardiovasc Prev Rehabil. 2006;13:846–848.
    1. García-Lledó A, Rodríguez-Martín S, Tobías A, Alonso-Martín J, Ansede-Cascudo JC, de Abajo FJ. Heat waves, ambient temperature, and risk of myocardial infarction: an ecological study in the Community of Madrid. Rev Esp Cardiol (Engl Ed) 2020;73:300–306.
    1. Lin S, Soim A, Gleason KA, Hwang SA. Association Between Low Temperature During Winter Season and Hospitalizations for Ischemic Heart Diseases in New York State. J Environ Health. 2016;78:66–74.
    1. Ravljen M, Bilban M, Kajfež-Bogataj L, Hovelja T, Vavpotič D. Influence of daily individual meteorological parameters on the incidence of acute coronary syndrome. Int J Environ Res Public Health. 2014;11:11616–11626.
    1. Chang CL, Shipley M, Marmot M, Poulter N. Lower ambient temperature was associated with an increased risk of hospitalization for stroke and acute myocardial infarction in young women. J Clin Epidemiol. 2004;57:749–757.
    1. Madrigano J, Mittleman MA, Baccarelli A, Goldberg R, Melly S, von Klot S, Schwartz J. Temperature, myocardial infarction, and mortality: effect modification by individual- and area-level characteristics. Epidemiology. 2013;24:439–446.
    1. Hori A, Hashizume M, Tsuda Y, Tsukahara T, Nomiyama T. Effects of weather variability and air pollutants on emergency admissions for cardiovascular and cerebrovascular diseases. Int J Environ Health Res. 2012;22:416–430.
    1. Mohammad MA, Koul S, Rylance R, Fröbert O, Alfredsson J, Sahlén A, Witt N, Jernberg T, Muller J, Erlinge D. Association of Weather With Day-to-Day Incidence of Myocardial Infarction: A SWEDEHEART Nationwide Observational Study. JAMA Cardiol. 2018;3:1081–1089.
    1. Danet S, Richard F, Montaye M, Beauchant S, Lemaire B, Graux C, Cottel D, Marécaux N, Amouyel P. Unhealthy effects of atmospheric temperature and pressure on the occurrence of myocardial infarction and coronary deaths. A 10-year survey: the Lille-World Health Organization MONICA project (Monitoring trends and determinants in cardiovascular disease) Circulation. 1999;100:E1–E7.
    1. Abrignani MG, Corrao S, Biondo GB, Renda N, Braschi A, Novo G, Di Girolamo A, Braschi GB, Novo S. Influence of climatic variables on acute myocardial infarction hospital admissions. Int J Cardiol. 2009;137:123–129.
    1. Sharif Nia H, Chan YH, Froelicher ES, Pahlevan Sharif S, Yaghoobzadeh A, Jafari A, Goudarzian AH, Pourkia R, Haghdoost AA, Arefinia F, Nazari R. Weather fluctuations: predictive factors in the prevalence of acute coronary syndrome. Health Promot Perspect. 2019;9:123–130.
    1. Messner T, Lundberg V, Wikström B. A temperature rise is associated with an increase in the number of acute myocardial infarctions in the subarctic area. Int J Circumpolar Health. 2002;61:201–207.
    1. Bayentin L, El Adlouni S, Ouarda TB, Gosselin P, Doyon B, Chebana F. Spatial variability of climate effects on ischemic heart disease hospitalization rates for the period 1989-2006 in Quebec, Canada. Int J Health Geogr. 2010;9:5.
    1. Mirić D, Rumboldt Z. The impact of meteorological factors on the onset of myocardial infarction in the coastal region of middle Dalmatia. G Ital Cardiol. 1993;23:655–660.
    1. Bhaskaran K, Hajat S, Haines A, Herrett E, Wilkinson P, Smeeth L. Effects of ambient temperature on the incidence of myocardial infarction. Heart. 2009;95:1760–1769.
    1. Nastos PT, Giaouzaki KN, Kampanis NA, Matzarakis A. Acute coronary syndromes related to bio-climate in a Mediterranean area. The case of Ierapetra, Crete Island, Greece. Int J Environ Health Res. 2013;23:76–90.
    1. Sun Z, Chen C, Xu D, Li T. Effects of ambient temperature on myocardial infarction: A systematic review and meta-analysis. Environ Pollut. 2018;241:1106–1114.
    1. Abrignani MG, Corrao S, Biondo GB, Lombardo RM, Di Girolamo P, Braschi A, Di Girolamo A, Novo S. Effects of ambient temperature, humidity, and other meteorological variables on hospital admissions for angina pectoris. Eur J Prev Cardiol. 2012;19:342–348.
    1. Bijelović S, Dragić N, Bijelović M, Kovačević M, Jevtić M, Ninkovic Mrđenovački O. Impact of climate conditions on hospital admissions for subcategories of cardiovascular diseases. Med Pr. 2017;68:189–197.
    1. Cheng TO. Myocardial infarction and the weather: a significant positive correlation between the onset of heart infarct and 28 KHz atmospherics--a pilot study. Clin Cardiol. 1985;8:510.
    1. Vencloviene J, Babarskiene R, Dobozinskas P, Siurkaite V. Effects of weather conditions on emergency ambulance calls for acute coronary syndromes. Int J Biometeorol. 2015;59:1083–1093.
    1. Goerre S, Egli C, Gerber S, Defila C, Minder C, Richner H, Meier B. Impact of weather and climate on the incidence of acute coronary syndromes. Int J Cardiol. 2007;118:36–40.
    1. Baker-Blocker A. Winter weather and cardiovascular mortality in Minneapolis-St. Paul. Am J Public Health. 1982;72:261–265.
    1. Auger N, Potter BJ, Smargiassi A, Bilodeau-Bertrand M, Paris C, Kosatsky T. Association between quantity and duration of snowfall and risk of myocardial infarction. CMAJ. 2017;189:E235–E242.
    1. Gebhard C, Gebhard CE, Stähli BE, Maafi F, Bertrand MJ, Wildi K, Fortier A, Galvan Onandia Z, Toma A, Zhang ZW, Smith DC, Spagnoli V, Ly HQ. Weather and risk of ST-elevation myocardial infarction revisited: Impact on young women. PLoS One. 2018;13:e0195602.
    1. Morabito M, Modesti PA, Cecchi L, Crisci A, Orlandini S, Maracchi G, Gensini GF. Relationships between weather and myocardial infarction: a biometeorological approach. Int J Cardiol. 2005;105:288–293.
    1. Morabito M, Crisci A, Grifoni D, Orlandini S, Cecchi L, Bacci L, Modesti PA, Gensini GF, Maracchi G. Winter air-mass-based synoptic climatological approach and hospital admissions for myocardial infarction in Florence, Italy. Environ Res. 2006;102:52–60.
    1. Messner T, Lundberg V, Wikström B. The Arctic Oscillation and incidence of acute myocardial infarction. J Intern Med. 2003;253:666–670.
    1. Stewart S, Moholdt TT, Burrell LM, Sliwa K, Mocumbi AO, McMurray JJ, Keates AK, Hawley JA. Winter Peaks in Heart Failure: An Inevitable or Preventable Consequence of Seasonal Vulnerability? Card Fail Rev. 2019;5:83–85.
    1. Escolar V, Lozano A, Larburu N, Kerexeta J, Álvarez R, Juez B, Echebarria A, Azcona A, Artola G. Impact of environmental factors on heart failure decompensations. ESC Heart Fail. 2019;6:1226–1232.
    1. Ryti NR, Mäkikyrö EM, Antikainen H, Junttila MJ, Hookana E, Ikäheimo TM, Kortelainen ML, Huikuri HV, Jaakkola JJ. Cold spells and ischaemic sudden cardiac death: effect modification by prior diagnosis of ischaemic heart disease and cardioprotective medication. Sci Rep. 2017;7:41060.
    1. Chung FP, Li HR, Chong E, Pan CH, Lin YJ, Chang SL, Lo LW, Hu YF, Tuan TC, Chao TF, Liao JN, Lin WY, Shaw KP, Chen SA. Seasonal variation in the frequency of sudden cardiac death and ventricular tachyarrhythmia in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy: the effect of meteorological factors. Heart Rhythm. 2013;10:1859–1866.
    1. Benouaich V, Soler P, Gourraud PA, Lopez S, Rousseau H, Marcheix B. Impact of meteorological conditions on the occurrence of acute type A aortic dissections. Interact Cardiovasc Thorac Surg. 2010;10:403–406.
    1. Kordzadeh A, Askari A, Panayiotopoulos Y. Atmospheric pressure and infra-renal abdominal aortic aneurysm rupture: a single observational study and a comprehensive review of literature. Int J Surg. 2013;11:458–462.
    1. Low RB, Bielory L, Qureshi AI, Dunn V, Stuhlmiller DF, Dickey DA. The relation of stroke admissions to recent weather, airborne allergens, air pollution, seasons, upper respiratory infections, and asthma incidence, September 11, 2001, and day of the week. Stroke. 2006;37:951–957.
    1. Dawson J, Weir C, Wright F, Bryden C, Aslanyan S, Lees K, Bird W, Walters M. Associations between meteorological variables and acute stroke hospital admissions in the west of Scotland. Acta Neurol Scand. 2008;117:85–89.
    1. Matsumoto M, Ishikawa S, Kajii E. Cumulative effects of weather on stroke incidence: a multi-community cohort study in Japan. J Epidemiol. 2010;20:136–142.
    1. Royé D, Zarrabeitia MT, Riancho J, Santurtún A. A time series analysis of the relationship between apparent temperature, air pollutants and ischemic stroke in Madrid, Spain. Environ Res. 2019;173:349–358.
    1. Ravljen M, Bajrović F, Vavpotič D. A time series analysis of the relationship between ambient temperature and ischaemic stroke in the Ljubljana area: immediate, delayed and cumulative effects. BMC Neurol. 2021;21:23.
    1. Wang X, Cao Y, Hong D, Zheng D, Richtering S, Sandset EC, Leong TH, Arima H, Islam S, Salam A, Anderson C, Robinson T, Hackett ML. Ambient Temperature and Stroke Occurrence: A Systematic Review and Meta-Analysis. Int J Environ Res Public Health. 2016;13
    1. Webb L, Bambrick H, Tait P, Green D, Alexander L. Effect of ambient temperature on Australian northern territory public hospital admissions for cardiovascular disease among indigenous and non-indigenous populations. Int J Environ Res Public Health. 2014;11:1942–1959.
    1. Kwon BY, Lee E, Lee S, Heo S, Jo K, Kim J, Park MS. Vulnerabilities to Temperature Effects on Acute Myocardial Infarction Hospital Admissions in South Korea. Int J Environ Res Public Health. 2015;12:14571–14588.
    1. Hajat S, Kovats RS, Lachowycz K. Heat-related and cold-related deaths in England and Wales: who is at risk? Occup Environ Med. 2007;64:93–100.
    1. Wong HT, Lai PC. Weather inference and daily demand for emergency ambulance services. Emerg Med J. 2012;29:60–64.
    1. Grech V, Aquilina O, Pace J. Gender differences in seasonality of acute myocardial infarction admissions and mortality in a population-based study. J Epidemiol Community Health. 2001;55:147–148.
    1. Zheng S, Wang M, Li B, Wang S, He S, Yin L, Shang K, Li T. Gender, Age and Season as Modifiers of the Effects of Diurnal Temperature Range on Emergency Room Admissions for Cause-Specific Cardiovascular Disease among the Elderly in Beijing. Int J Environ Res Public Health. 2016;13
    1. Radišauskas R, Bernotienė G, Bacevičienė M, Ustinavičienė R, Kirvaitienė J, Krančiukaitė-Butylkinienė D. Trends of myocardial infarction morbidity and its associations with weather conditions. Medicina (Kaunas) 2014;50:182–189.
    1. Medina-Ramón M, Zanobetti A, Cavanagh DP, Schwartz J. Extreme temperatures and mortality: assessing effect modification by personal characteristics and specific cause of death in a multi-city case-only analysis. Environ Health Perspect. 2006;114:1331–1336.
    1. Vandentorren S, Bretin P, Zeghnoun A, Mandereau-Bruno L, Croisier A, Cochet C, Ribéron J, Siberan I, Declercq B, Ledrans M. August 2003 heat wave in France: risk factors for death of elderly people living at home. Eur J Public Health. 2006;16:583–591.
    1. Foroni M, Salvioli G, Rielli R, Goldoni CA, Orlandi G, Zauli Sajani S, Guerzoni A, Maccaferri C, Daya G, Mussi C. A retrospective study on heat-related mortality in an elderly population during the 2003 heat wave in Modena, Italy: the Argento Project. J Gerontol A Biol Sci Med Sci. 2007;62:647–651.
    1. Bouchama A, Dehbi M, Mohamed G, Matthies F, Shoukri M, Menne B. Prognostic factors in heat wave related deaths: a meta-analysis. Arch Intern Med. 2007;167:2170–2176.
    1. Kaiser R, Le Tertre A, Schwartz J, Gotway CA, Daley WR, Rubin CH. The effect of the 1995 heat wave in Chicago on all-cause and cause-specific mortality. Am J Public Health. 2007;97 Suppl 1:S158–S162.
    1. Marí-Dell'Olmo M, Tobías A, Gómez-Gutiérrez A, Rodríguez-Sanz M, García de Olalla P, Camprubí E, Gasparrini A, Borrell C. Social inequalities in the association between temperature and mortality in a South European context. Int J Public Health. 2019;64:27–37.
    1. Crawford VL, McNerlan SE, Stout RW. Seasonal changes in platelets, fibrinogen and factor VII in elderly people. Age Ageing. 2003;32:661–665.
    1. Ockene IS, Chiriboga DE, Stanek EJ 3rd, Harmatz MG, Nicolosi R, Saperia G, Well AD, Freedson P, Merriam PA, Reed G, Ma Y, Matthews CE, Hebert JR. Seasonal variation in serum cholesterol levels: treatment implications and possible mechanisms. Arch Intern Med. 2004;164:863–870.
    1. Sher L. Seasonal distribution of myocardial infarction and seasonal mood changes. J Am Coll Cardiol. 1999;33:2088–2089.
    1. Kloner RA, Poole WK, Perritt RL. When throughout the year is coronary death most likely to occur? Circulation. 1999;100:1630–1634.
    1. Houdas Y, Deklunder G, Lecroart JL. Cold exposure and ischemic heart disease. Int J Sports Med. 1992;13 Suppl 1:S179–S181.
    1. Giaconi S, Ghione S, Palombo C, Genovesi-Ebert A, Marabotti C, Fommei E, Donato L. Seasonal influences on blood pressure in high normal to mild hypertensive range. Hypertension. 1989;14:22–27.
    1. Marchant B, Donaldson G, Mridha K, Scarborough M, Timmis AD. Mechanisms of cold intolerance in patients with angina. J Am Coll Cardiol. 1994;23:630–636.
    1. Cheng X, Su H. Effects of climatic temperature stress on cardiovascular diseases. Eur J Intern Med. 2010;21:164–167.
    1. De Lorenzo F, Kadziola Z, Mukherjee M, Saba N, Kakkar VV. Haemodynamic responses and changes of haemostatic risk factors in cold-adapted humans. QJM. 1999;92:509–513.
    1. Ikäheimo TM. Cardiovascular diseases, cold exposure and exercise. Temperature (Austin) 2018;5:123–146.
    1. Edwards DG, Gauthier AL, Hayman MA, Lang JT, Kenefick RW. Acute effects of cold exposure on central aortic wave reflection. J Appl Physiol (1985) 2006;100:1210–1214.
    1. Widlansky ME, Vita JA, Keyes MJ, Larson MG, Hamburg NM, Levy D, Mitchell GF, Osypiuk EW, Vasan RS, Benjamin EJ. Relation of season and temperature to endothelium-dependent flow-mediated vasodilation in subjects without clinical evidence of cardiovascular disease (from the Framingham Heart Study) Am J Cardiol. 2007;100:518–523.
    1. Hiramatsu K, Yamada T, Katakura M. Acute effects of cold on blood pressure, renin-angiotensin-aldosterone system, catecholamines and adrenal steroids in man. Clin Exp Pharmacol Physiol. 1984;11:171–179.
    1. Hampel R, Breitner S, Rückerl R, Frampton MW, Koenig W, Phipps RP, Wichmann HE, Peters A, Schneider A. Air temperature and inflammatory and coagulation responses in men with coronary or pulmonary disease during the winter season. Occup Environ Med. 2010;67:408–416.
    1. Elwood PC, Beswick A, O'Brien JR, Renaud S, Fifield R, Limb ES, Bainton D. Temperature and risk factors for ischaemic heart disease in the Caerphilly prospective study. Br Heart J. 1993;70:520–523.
    1. Modesti PA, Morabito M, Bertolozzi I, Massetti L, Panci G, Lumachi C, Giglio A, Bilo G, Caldara G, Lonati L, Orlandini S, Maracchi G, Mancia G, Gensini GF, Parati G. Weather-related changes in 24-hour blood pressure profile: effects of age and implications for hypertension management. Hypertension. 2006;47:155–161.
    1. Hassi J, Rintamäki H, Ruskoaho H, Leppäluoto J, Vuolteenaho O. Plasma levels of endothelin-1 and atrial natriuretic peptide in men during a 2-hour stay in a cold room. Acta Physiol Scand. 1991;142:481–485.
    1. Kolar J, Bhatnagar SK, Hudak A, Smid J, al-Yusuf AR. The effect of a hot dry climate on the haemorrheology of healthy males and patients with acute myocardial infarction. J Trop Med Hyg. 1988;91:77–82.
    1. Gronlund CJ, Sheppard L, Adar SD, O'Neill MS, Auchincloss A, Madrigano J, Kaufman J, Diez Roux AV. Vulnerability to the Cardiovascular Effects of Ambient Heat in Six US Cities: Results from the Multi-Ethnic Study of Atherosclerosis (MESA) Epidemiology. 2018;29:756–764.
    1. Ren C, O'Neill MS, Park SK, Sparrow D, Vokonas P, Schwartz J. Ambient temperature, air pollution, and heart rate variability in an aging population. Am J Epidemiol. 2011;173:1013–1021.
    1. Scragg R, Jackson R, Holdaway IM, Lim T, Beaglehole R. Myocardial infarction is inversely associated with plasma 25-hydroxyvitamin D3 levels: a community-based study. Int J Epidemiol. 1990;19:559–563.
    1. Ren C, Williams GM, Mengersen K, Morawska L, Tong S. Temperature enhanced effects of ozone on cardiovascular mortality in 95 large US communities, 1987-2000: Assessment using the NMMAPS data. Arch Environ Occup Health. 2009;64:177–184.
    1. Burkart K, Canário P, Breitner S, Schneider A, Scherber K, Andrade H, Alcoforado MJ, Endlicher W. Interactive short-term effects of equivalent temperature and air pollution on human mortality in Berlin and Lisbon. Environ Pollut. 2013;183:54–63.
    1. Willers SM, Jonker MF, Klok L, Keuken MP, Odink J, van den Elshout S, Sabel CE, Mackenbach JP, Burdorf A. High resolution exposure modelling of heat and air pollution and the impact on mortality. Environ Int. 2016;89-90:102–109.
    1. Scortichini M, De Sario M, de'Donato FK, Davoli M, Michelozzi P, Stafoggia M. Short-Term Effects of Heat on Mortality and Effect Modification by Air Pollution in 25 Italian Cities. Int J Environ Res Public Health. 2018;15
    1. Qin RX, Xiao C, Zhu Y, Li J, Yang J, Gu S, Xia J, Su B, Liu Q, Woodward A. The interactive effects between high temperature and air pollution on mortality: A time-series analysis in Hefei, China. Sci Total Environ. 2017;575:1530–1537.
    1. Faergeman O. Climate change and preventive medicine. Eur J Cardiovasc Prev Rehabil. 2007;14:726–729.

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