The Syndrome We Agreed to Call Bronchiolitis

Fernando P Polack, Renato T Stein, Adnan Custovic, Fernando P Polack, Renato T Stein, Adnan Custovic

Abstract

We are ignoring evidence suggesting that the diagnosis of bronchiolitis encompasses several diseases with distinct underlying mechanisms, considerable heterogeneity in treatment responses, and ultimately different therapeutic targets. Understanding this heterogeneity may be the only way to deliver appropriate, stratified treatments.

Keywords: bronchiolitis; endotypes; machine learning; respiratory syncytial virus.

© The Author(s) 2019. Published by Oxford University Press for the Infectious Diseases Society of America.

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Source: PubMed

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