Clinical characteristics of patients with diabetic polyneuropathy: the role of clinical and electromyographic evaluation and the effect of the various types on the quality of life

N Ovayolu, E Akarsu, E Madenci, S Torun, O Ucan, M Yilmaz, N Ovayolu, E Akarsu, E Madenci, S Torun, O Ucan, M Yilmaz

Abstract

Objective: This study was performed to identify the relationship between the quality of life and polyneuropathy which is one of the complications of diabetes.

Methods: Total 111 patients with diabetes mellitus were taken into the study as type 1 and type 2. Patients were accepted having polyneuropathy according to their electroneuromyography (ENMG) results. To evaluate the quality of life in the patients Short Form 36 (SF-36) and World Health Organization Quality of Life Questionnaire abbreviated version (WHOQOL-BREF) were used.

Results: Clinical polyneuropathy was found in 46% of the patients, while polineuropathy was found in 63% of the patients with evaluation ENMG. The patients with polyneuropathy had poor quality of life according to SF-36 and WHOQOL-BREF (p < 0.001). The mean quality of life scores of patients who had sensoriomotor and mix polyneuropathy, were lower than sensory type and axonal polyneuropathy.

Conclusion: Diabetic polyneuropathy influences the quality of life in a negative way. The quality of life scores of patients who had polyneuropathy continuing with mixed pathogenesis and sensoriomotor type, become worse for this reason, even if the patients do not have any clinical polyneuropathy, this being evaluated with ENMG.

References

    1. Scheen AJ. Diabetes mellitus: from clinical knowledge to public health concern. J Soc Biol. 2007;201:133–40.
    1. Boulton AJ. Diabetic neuropathy: classification, measurement and treatment. Curr Opin Endocrinol Diabetes Obes. 2007;14:141–5.
    1. Pastore C, Izura V, Geijo-Barrientos E, Dominguez JR. A comparison of electrophysiological tests for the early diagnosis of diabetic neuropathy. Muscle Nerve. 1999;22:1667–73.
    1. Wilson J, Chawla J, Fisher M. Sensitivity and specificity of electrodiagnostic criteria for CIDP using ROC curves: comparison to patients with diabetic and MGUS associated neuropathies. J Neurol Sci. 2005;231:19–28.
    1. Vinik A, Ullal J, Parson HK, Casellini CM. Diabetic neuropathies: clinical manifestations and current treatment options. Nat Clin Pract Endocrinol Metab. 2006;2:269–81.
    1. Vinik AI, Freeman R, Erbas T. Diabetic autonomic neuropathy. Semin Neurol. 2003;23:365–72.
    1. Jasik M. Therapy of diabetic neuropathy. Przegl Lek. 2003;60:167–9.
    1. Rubin RR, Peyrot M. Quality of life and diabetes. Diabetes Metab Res Rev. 1999;15:205–18.
    1. Acaray A, Pınar R. Quality of life in Turkish hemodialysis patients. Int Urol Nephrol. 2005;37:595–602.
    1. Zangaro GA, Hull MM. Diabetic neuropathy: pathophysiology and prevention of foot ulcers. Clin Nurse Spec. 1999;13:57–65.
    1. Jerums G, MacIsaac RJ. Treatment of microalbuminuria in patients with type 2 diabetes mellitus. Treat Endocrinol. 2002;1:163–73.
    1. Ware JE, Sherbourne DC. The MOS 36 item short-form health survey (SF-36) Med Care. 1992;30:473–83.
    1. Pınar R. A new aspect of health-related research: quality of life, evaluation of reliability and validity of a quality of life survey in patients with chronic diseases. Hemsirelik Bulteni. 1995;9:85–95.
    1. Bowling A. Measuring Health. A Review of Quality of Life Measurement Scales. 2nd edn. Philadelphia, PA: Open University Press; 1997. pp. 57–60.
    1. Jacobson AM, Groot M, Samson JA. The evaluation of two measures of quality of life in patient with type I and type II diabetes. Diabetes Care. 1994;17:267–74.
    1. Anderson RM, Fitzgerald JT, Wisdom K, Davis WK, Hiss RG. A comparison of global versus disease-specific quality of life measure in patients with NIDDM. Diabetes Care. 1997;20:299–305.
    1. Leung KF, Tay M, Cheng SSW, Lin F. Hong-Kong Chinese Version World Health Organization Quality of Life Measure Abbreviated Version. WHOQOLBREF (HK) Hong Kong: Hong Kong Hospital Authority; 1997.
    1. Fidaner H, Elbi H, Fidaner C, Eser SY, Eser E. WHOQOL-100 ve WHOQOL-BREF’in Psikometrik Özellikleri. 3P Dergisi. 1999;7:23–40.
    1. Oh SJ. In: Clinical Electromyography. Nerve Conduction Studies. Normal Values for Common Nerve Conduction Tests. 2nd edn. Oh SJ, editor. Baltimore, MD: Lippincott, Williams & Wilkins; 1993. pp. 84–104. Edited by.
    1. De Pablos PL, Martinez J, Martinez MP, Doreste JA. Prevalence of micro- and macroalbuminuria in a Canadian population of type 2 diabetic patients. Relationship with blood pressure, lipid profile, obesity and metabolic control. Diabetes Metab. 1998;24:337–43.
    1. Gimbel JS, Richards P, Portenoy RK. Controlled-release oxycodone for pain in diabetic neuropathy: a Randomized Controlled Trial. Neurology. 2003;60:927–34.
    1. Park TS, Park JH, Baek HS. Can diabetic neuropathy be prevented. Diabetes Res Clin Pract. 2004;66:53–6.
    1. Kastenbaur T, Irsigler P, Sauseng S, Grimm A, Prager R. The prevalence of symptoms of sensorimotor and autonomic neuropathy in type 1 and type 2 diabetic subjects. J Diabetes Complications. 2004;18:27–31.
    1. Boulton AJM. Management of diabetic peripheral neuropathy. Clin Diabetes. 2005;23:9–15.
    1. Veglio M, Sivieri R. Prevalence of neuropathy in IDDM patients in Piemonte, Italy. The neuropathy study group of the Italian society for the study of diabetes, Piemonte Affiliate. Diabetes Care. 1993;16:456–61.
    1. Cabezas-Cerrato J. The prevalence of clinical diabetic polyneuropathy in Spain: a study in primary care and hospital clinic groups. Neuropathy Spanish Study Group of the Spanish Diabetes Society. Diabetologia. 1998;41:1263–9.
    1. Apostolou T, Gokal R. Neuropathy and quality of life in diabetic continuous ambulatory peritoneal dialysis patients. Perit Dial Int. 1999;19:S242–7.
    1. Barbosa AP, Medine JL, Ramos EP, Barros HP. Prevalence and risk factors of clinical diabetic polyneuropathy in a Portuguese primary health population. Diabetes Metab. 2001;27:496–502. 4 part 1.
    1. Daousi C, MacFarlane IA, Woodward A, Nurmikko TJ, Bundred PE, Benbow SJ. Chronic painful peripheral neuropathy in an urban community: a controlled comparison of people with and without diabetes. Diabet Med. 2004;21:976–82.
    1. Preston DC, Shapiro BE. Electromyography and Neuromuscular Disorders Polyneuropathy. Boston, MA: Butterworth-Heinemann; 1998. pp. 355–89.
    1. Lloyd A, Sawyer W, Hopkinson P. Impact of long-term complications on quality of life in patients with type 2 diabetes not using insulin. Value Health. 2001;4:392–400.
    1. Saperstein DS, Katz JS, Amato AA, Barohn RJ. Clinical spectrum of chronic acquired demyelinating polyneuropathies. Muscle Nerve. 2001;24:311–24.
    1. Larsson D, Lager I, Nilsson PM. Socio-economic characteristics and quality of life in diabetes mellitus relation to metabolic control. Scand J Public Health. 1999;27:101–5.
    1. Caldwell EM, Baxter J, Mitchell CM, Shetterly SM, Hamman RF. The Association of non-insulin dependent diabetes mellitus with perceived quality of life in a Biethnic Population: the San Luis Valley Diabetes Study. Am J Public Health. 1998;88:1225–9.
    1. Vileikyte L, Peyrot M, Bundy C, et al. The development and validation of a neuropathy- and foot ulcer-specific quality of life instrument. Diabetes Care. 2003;26:2549–55.
    1. Teunissen LL, Eurelings NC, Notermans NC, Hop JW, Gijn JV. Quality of life patients with axonal polyneuropathy. J Neurol. 2000;247:195–9.
    1. Perkins BA, Olaleye D, Bril V. Carpal tunnel syndrome in patients with diabetic polyneuropathy. Diabetes Care. 2002;25:565–9.
    1. Testa MA, Simonson DC, Turner RR. Valuing quality of life and improvements in glycemic control in people with type 2 diabetes. Diabetes Care. 1998;21:C44–52.
    1. Ozer E, Sengül A, Gedik S, et al. Diabetes Education: A Chance to Improve Well-Being of Turkish People With Type 2 Diabetes. Paris: 18. International Diabetes Federation Congress; 2003. August 24–29.
    1. Milenkoviç T, Percan V, Petrovski G, Markoviç Temelkova S, Stefanovska Balabanova G. Quality of Life in Diabetic Patients After 5-Day Structured Teaching Program. Paris: 18. International Diabetes Fedaration Congress; 2003. August 24–29.
    1. Suguna N, Neelima G, Yugandhar K, Satyanarayana K, Rao PV. Association Among SF36 Quality of Life Measures and Glycemic Control in Asian Indians With Diabetes. Paris: 18. International Diabetes Fedaration Congress; 2003. August 24–29.
    1. Vivian EM, Kleppinger E. Evaluating the Quality of Life of Veterans With Type II Diabetes Mellitus. Paris: 18. International Diabetes Fedaration Congress; 2003. August 24–29.
    1. Salman S, Sengül A, Ozer E, et al. Post-Earthquake Glycemic Control and Quality of Life: Investigation in Type 1 Diabetics after Great Marmara Earthquake. Paris: 18. International Diabetes Federation Congress; 2003. August 24–29.
    1. Cameron NE, Eaton SE, Cotter MA, Tesfaye S. Vascular factors and metabolic interactions in the pathogenesis of diabetic neuropathy. Diabetologia. 2001;44:1973–88.
    1. Van de Poll-Franse LV, Valk GD, Render CM, Heine RJ, Van Eijk JT. Longitudinal assessment of the development of diabetic polyneuropathy and associated risk factors. Diabet Med. 2002;19:771–6.

Source: PubMed

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