Prognostic value of a modified surprise question designed for use in the emergency department setting

Samir A Haydar, Tania D Strout, Alicia G Bond, Paul Kj Han, Samir A Haydar, Tania D Strout, Alicia G Bond, Paul Kj Han

Abstract

Objective: Few reliable and valid prognostic tools are available to help emergency physicians identify patients who might benefit from early palliative approaches. We sought to determine if responses to a modified version of the surprise question, "Would you be surprised if this patient died in the next 30 days" could predict in-hospital mortality and resource utilization for hospitalized emergency department patients.

Methods: For this observational study, emergency physicians responded to the modified surprise question with each admission over a five-month study period. Logistic regression analyses were completed and standard test characteristics evaluated.

Results: 6,122 visits were evaluated. Emergency physicians responded negatively to the modified surprise question in 918 (15.1%). Test characteristics for in-hospital mortality were: sensitivity 32%, specificity 85%, positive predictive value 6%, negative predictive value 98%. The risk of intensive care unit use (relative risk [RR], 1.87; 95% confidence interval [CI], 1.45 to 2.40), use of 'comfort measures' orders (RR, 3.43; 95% CI, 2.81 to 4.18), palliative-care consultation (RR, 3.06; 95% CI, 2.62 to 3.56), and in-hospital mortality (RR, 2.18; 95% CI, 1.72 to 2.76) were greater for patients with negative responses.

Conclusion: The modified surprise question is a simple trigger for palliative care needs, accurately identifying those at greater risk for in-hospital mortality and resource utilization. With a negative predictive value of 98%, affirmative responses to the modified surprise question provide reassurance that in-hospital death is unlikely.

Keywords: Emergency service, hospital; Palliative medicine; Surprise question; Terminal care.

Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

References

    1. Grudzen CR, Richardson LD, Johnson PN, et al. Emergency department-initiated palliative care in advanced cancer: a randomized clinical trial. JAMA Oncol. 2016 Jan 14; doi: 10.1001/jamaoncol.2015.5252.
    1. Delgado-Guay MO, Kim YJ, Shin SH, et al. Avoidable and unavoidable visits to the emergency department among patients with advanced cancer receiving outpatient palliative care. J Pain Symptom Manage. 2015;49:497–504.
    1. George N, Phillips E, Zaurova M, Song C, Lamba S, Grudzen C. Palliative care screening and assessment in the emergency department: a systematic review. J Pain Symptom Manage. 2016;51:108–19.
    1. Wu FM, Newman JM, Lasher A, Brody AA. Effects of initiating palliative care consultation in the emergency department on inpatient length of stay. J Palliat Med. 2013;16:1362–7.
    1. Kistler EA, Sean Morrison R, Richardson LD, Ortiz JM, Grudzen CR. Emergency department-triggered palliative care in advanced cancer: proof of concept. Acad Emerg Med. 2015;22:237–9.
    1. George N, Barrett N, McPeake L, Goett R, Anderson K, Baird J. Content validation of a novel screening tool to identify emergency department patients with significant palliative care needs. Acad Emerg Med. 2015;22:823–37.
    1. Rhee J, Clayton JM. The ‘surprise’ question may improve the accuracy of GPs in identifying death in patients with advanced stage IV solid-cell cancer. Evid Based Med. 2015;20:71.
    1. Hamano J, Morita T, Inoue S, et al. Surprise questions for survival prediction in patients with advanced cancer: a multicenter prospective cohort study. Oncologist. 2015;20:839–44.
    1. Feyi K, Klinger S, Pharro G, et al. Predicting palliative care needs and mortality in end stage renal disease: use of an at-risk register. BMJ Support Palliat Care. 2015;5:19–25.
    1. O’Callaghan A, Laking G, Frey R, Robinson J, Gott M. Can we predict which hospitalised patients are in their last year of life? A prospective cross-sectional study of the Gold Standards Framework Prognostic Indicator Guidance as a screening tool in the acute hospital setting. Palliat Med. 2014;28:1046–52.
    1. Green SB. How many subjects does it take to do a regression analysis. Multivariate Behav Res. 1991;26:499–510.
    1. Cohen J, Cohen P. Applied multiple regression/correlation analysis for the behavioral sciences. Hillsdale, NJ: Erlbaum; 1975.
    1. Temel JS, Greer JA, Muzikansky A, et al. Early palliative care for patients with metastatic non-small-cell lung cancer. N Engl J Med. 2010;363:733–42.
    1. Knott DA, Hiestand BC. If not us, then who? Palliative care referral from the emergency department. Acad Emerg Med. 2015;22:227–8.
    1. Bowman J, George N, Barrett N, Anderson K, Dove-Maguire K, Baird J. Acceptability and reliability of a novel palliative care screening tool among emergency department providers. Acad Emerg Med. 2016;23:694–702.

Source: PubMed

3
Subscribe