Minimally invasive ablation of a toxic thyroid nodule by high-intensity focused ultrasound

O Esnault, A Rouxel, E Le Nestour, G Gheron, L Leenhardt, O Esnault, A Rouxel, E Le Nestour, G Gheron, L Leenhardt

Abstract

HIFU is used in the treatment of cancer (prostate, breast) and uterine fibroma but not yet in TNs. This case report describes the first successful ablation of a toxic TN with HIFU. TSH and radioiodine scan normalization were achieved without complications and maintained for 18 months. HIFU treatment is a minimally invasive technique that may be an effective safe alternative to radioiodine or surgery in patients with toxic TNs.

Figures

Fig 1.
Fig 1.
Top, Transversal sonography scan shows a 9 × 8 mm solid isoechoic right isthmolobar nodule. Middle, Longitudinal power Doppler sonography shows hypervascularization before HIFU treatment. Bottom, Hot right isthmolobar nodule with near-total suppression of extranodular iodine uptake is shown by the 123I thyroid scan.
Fig 2.
Fig 2.
Recovery of extranodular iodine uptake 18 months after HIFU is shown by the 123I thyroid scan.

Source: PubMed

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