Percutaneous Left Atrial Appendage Closure With the LAmbre Device for Stroke Prevention in Atrial Fibrillation: A Prospective, Multicenter Clinical Study
He Huang, Yu Liu, Yawei Xu, Zulu Wang, Yigang Li, Kejiang Cao, Shu Zhang, Yanzong Yang, Xinchun Yang, Dejia Huang, Bo Yu, Xi Su, Liqun Wu, Congxin Huang, He Huang, Yu Liu, Yawei Xu, Zulu Wang, Yigang Li, Kejiang Cao, Shu Zhang, Yanzong Yang, Xinchun Yang, Dejia Huang, Bo Yu, Xi Su, Liqun Wu, Congxin Huang
Abstract
Objectives: The authors sought to assess the clinical outcomes of left atrial appendage (LAA) closure with the LAmbre closure system in patients with nonvalvular atrial fibrillation (NVAF).
Background: Over 90% of thrombi are located in the LAA in NVAF patients.
Methods: A prospective, multicenter study was conducted in 153 NVAF patients with CHADS2 score ≥1.
Results: The LAA was successfully occluded in 152 patients. Serious complications occurred in 5 patients. During the 12-month follow-up, ischemic stroke occurred in 2 patients, 1 patient had incomplete LAA sealing, and there was no device embolization.
Conclusions: LAA closure with the LAmbre device shows encouraging results for stroke prevention.
Keywords: LAmbre; atrial fibrillation; left atrial appendage closure; stroke.
Copyright © 2017. Published by Elsevier Inc.
Source: PubMed