New software for objective evaluation of brain glioblastoma resection degree
A L Krivoshapkin, G S Sergeev, A S Gaytan, V P Kurbatov, L E Kalneus, E G Tarantsev, A L Krivoshapkin, G S Sergeev, A S Gaytan, V P Kurbatov, L E Kalneus, E G Tarantsev
Abstract
The visual evaluation of the degree of GBM resection based upon postoperative enhanced MRI is still difficult. It is explained by intricate complex of tumor residual fragments, blood cells, hemostatic tissues and perifocal edema that located in the postoperative area. We introduce the new software-based method for postoperative MRI data's objective estimation. Five independent specialists had examined 16 patients' MRI data (including 12 GBM and 4 patients with noninfiltrative intracerebral tumors) and tested the method's specificity and sensitivity against the enhanced residual tumor (ERT). Our software determines the 100% sensitivity and specificity against hemostatic agent Surgicel, the high recurrence rate of results while estimating the volume of ERT (0,14 ± 0,02 cm³) and low considerable time (5,21 ± 0,14 min). The software was can be used both daily practice and research of malignant glioma management.
Source: PubMed