Association between BVAB1 and high Nugent scores among women with bacterial vaginosis

Christina A Muzny, Imran R Sunesara, Michael E Griswold, Ranjit Kumar, Elliot J Lefkowitz, Leandro A Mena, Jane R Schwebke, David H Martin, Edwin Swiatlo, Christina A Muzny, Imran R Sunesara, Michael E Griswold, Ranjit Kumar, Elliot J Lefkowitz, Leandro A Mena, Jane R Schwebke, David H Martin, Edwin Swiatlo

Abstract

As part of a larger study using 454 pyrosequencing to investigate the vaginal microbiota of women with bacterial vaginosis (BV), we found an association between a novel BV-associated bacterium (BVAB1) and high Nugent scores and propose that BVAB1 is the curved Gram-negative rod traditionally identified as Mobiluncus spp. in vaginal Gram stains.

Keywords: BVAB1; Bacterial vaginosis; Mobiluncus; Nugent score.

Copyright © 2014 Elsevier Inc. All rights reserved.

Figures

Fig. 1
Fig. 1
Estimated mean plot for mean number of Mobiluncus spp. and BVAB1 reads/sample among the cohort of women (n = 112). Black solid diamond: Estimated mean with 95% CI; black solid circle: Estimated mean with 95% CI; hollow diamonds or circles represent sequence counts of BVAB1 and Mobiluncus spp. reads for each observation, respectively.

Source: PubMed

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