Clinical Trials on ASS Deficiency

Total 10120 results

University Hospital Inselspital, Berne
Merck Sharp & Dohme LLC; Pfizer

Completed

Prevalence of Sexually Transmitted Infections (STIs) in HIV-infected Patients (CTNG)

HIV Infections | Herpes Simplex | Chlamydia Trachomatis | Neisseria Gonorrhoeae

Switzerland
NeurogesX

Completed

Tolerability of Three Local Anesthetic Formulations in Conjunction With NGX-4010 for the Treatment of Neuropathic Pain

HIV Infections | Pain | Diabetes Mellitus | Diabetic Neuropathies | Peripheral Nervous System Diseases | Neuralgia | Herpes Zoster | Polyneuropathies

United States
Peking University Third Hospital
Peking University; The First Affiliated Hospital of Anhui Medical University; First Affiliated Hospital, Sun Yat-Sen University and other collaborators

Recruiting

Multicenter Prospective Cohort Study of Twin Maternal-Child Dyads in China (ChiTwiMC)

Pre-Eclampsia | High Risk Pregnancy | Twin Pregnancy, Antepartum Condition or Complication | Pre-Term | Twin Dichorionic Diamniotic Placenta | Twin to Twin Transfusion as Antepartum Condition | Twin Placenta | Twin Monochorionic Diamniotic Placenta

China
Jordi Gol i Gurina Foundation

Not yet recruiting

Extraordinarily Fun Training Project in Compulsory Secondary Education - Sexually Transmitted Infections (FEDE-ITS)

Gonorrhea | Chlamydia Infections | Human Immunodeficiency Virus (HIV) | Human Papillomavirus (HPV) | Syphilis Infection | Gender Equity

Spain
Institut de Recherche pour le Developpement
Expertise France-L'Initiative; French National Research Institute for Sustainable...

Recruiting

User-friendly HIV Testing and Counseling Services

HIV Infections | Hepatitis C | Hepatitis B, Chronic | Sexually Transmitted Infection

Thailand
Paul Szabolcs

Recruiting

Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC (PRO-RIC)

Congenital Bone Marrow Failure Syndromes | Inflammatory Conditions | Primary Immunodeficiency (PID) | Inherited Metabolic Disorders (IMD) | Hereditary Anemias

United States
University of California, San Francisco

Completed

Study of Melphalan Drug Exposure in Pediatric Hematopoietic Stem Cell Transplant Patients

Sickle Cell Disease | Hemoglobinopathies | Thalassemia | Hematologic Malignancies | Immunodeficiencies | Fanconi's Anemia | Nonmalignant Diseases | Genetic Inborn Errors of Metabolism

United States
AbbVie

Completed

Efficacy and Safety of Glecaprevir/Pibrentasvir (ABT-493/ABT-530) in Treatment-Naive and Treatment-Experienced Asian Adults With Chronic Hepatitis C Virus Genotype (GT) 1 to GT6 Infection With Compensated Cirrhosis and With or Without Human Immunodeficiency Virus Co-Infection (VOYAGE-2)

Hepatitis C Virus (HCV)

China, Korea, Republic of
Oregon Health and Science University

Terminated

Dietary Cholesterol and Defects in Cholesterol Synthesis in Mevalonate Kinase Deficiency

Immune System Diseases | Lipid Metabolism, Inborn Errors | Mevalonic Aciduria | Mevalonate Kinase Deficiency | Periodic Fever Syndromes, Hereditary

United States
Lei Li

Unknown

MSI in Circulatory DNA of Endometrial Cancer

Lynch Syndrome | Endometrial Cancer | Microsatellite Instability | Circulating Tumor Cell

China
Centre Hospitalier Universitaire Dijon

Completed

Research Into the Molecular Bases of a New Phenotype Combining Premature White Hair, Polycystic Kidney Disease, Aortic Dilation/Dissection and Lymphopenia (BCL-2)

New Phenotype (Combining Premature White Hair, Polycystic Kidney Disease, Aortic Dilation/Dissection and Lymphopenia)

France
PETHEMA Foundation

Completed

LINFOTARGAM: Treatment With Chemotherapy Plus Rituximab and Highly Active Antiretroviral Therapy in Patients With Diffuse Large B Cell Lymphoma and Infection With the Human Immunodeficiency Virus (HIV) (LINFOTARGAM)

HIV Infections | Diffuse Large B Cell Lymphoma

Spain
National Cancer Institute (NCI)

Completed

The Effect of Oral Candidiasis on the Speech Production, Feeding Skills, and Self-Concept of Children and Adolescents With Symptomatic HIV Infection

HIV Infections | Speech Disorders | Candidiasis, Oral | Eating Disorders

United States
AIO-Studien-gGmbH
Novartis Pharmaceuticals; Assign Data Management and Biostatistics GmbH

Completed

Safety and Tolerability of Everolimus as Second-line Treatment in Poorly Differentiated Neuroendocrine Carcinoma / Neuroendocrine Carcinoma G3 (WHO 2010) and Neuroendocrine Tumor G3 - an Investigator Initiated Phase II Study (EVINEC)

Neuroendocrine Carcinoma, Grade 3 | Poorly Differentiated Malignant Neuroendocrine Carcinoma | Neuroendocrine Carcinoma, Grade 1 [Well-differentiated Neuroendocrine Carcinoma] That Switched to G3 | Neuroendocrine Carcinoma, Grade 2 [Moderately Differentiated Neuroendocrine Carcinoma]... and other conditions

Germany
Eline C. B. Eskes

Recruiting

Magnetic Resonance Spectroscopy in Acid Sphingomyelinase Deficiency (MONACO)

Asmd, Visceral Type

Netherlands
Louisiana State University Health Sciences Center...
Merck Sharp & Dohme LLC

Recruiting

Immunogenicity of Gardasil-9 HPV Vaccine in People Living With HIV (AGO-Gard)

Cervical Intraepithelial Neoplasia | Human Immunodeficiency Virus | Anal Intraepithelial Neoplasia | Papillomavirus Infection | Papillomavirus Vaccines | Serology | Oral Cavity Infection

United States
Thomas Benfield

Recruiting

Changes in Weight, Body Composition and Metabolic Parameters After Discontinuing Dolutegravir or Tenofovir Disproxil (AVERTAS-2)

HIV Infections | Obesity | Renal Insufficiency | Osteoporosis | Hiv | Weight Gain | HIV Lipodystrophy

Denmark
University Hospital, Essen

Recruiting

HIV-HEART Aging Study (HIVH)

Myocardial Infarction | HIV Infections | Heart Failure | Coronary Disease | Aging | Weight Gain | HIV Encephalopathy

Germany
ANRS, Emerging Infectious Diseases
University Hospital, Geneva; University of Bordeaux; International Agency for... and other collaborators

Recruiting

Evaluation of Triage Options After HPV Testing for Cervical Cancer Screening Among HIV-infected Women (AIMA-CC)

HIV Infections | HPV - Anogenital Human Papilloma Virus Infection

Burkina Faso, Cambodia, Côte D'Ivoire
Gynecologic Oncology Group
National Cancer Institute (NCI)

Not yet recruiting

Biomarkers in Samples From Patients With Endometrial Cancer

Lynch Syndrome | Recurrent Uterine Corpus Carcinoma | Stage I Uterine Corpus Cancer | Stage II Uterine Corpus Cancer | Stage III Uterine Corpus Cancer | Stage IV Uterine Corpus Cancer

United States
National Human Genome Research Institute (NHGRI)

Recruiting

Clinical and Basic Investigations Into Hermansky-Pudlak Syndrome

Hermansky-Pudlak Syndrome (HPS)

United States
SPP Pharmaclon Ltd.
North-Western State Medical University named after I.I.Mechnikov

Completed

Study of Interferon-Gamma in the Complex Treatment of Patients Infected With HIV and Tuberculosis (MSPB_TB)

RNA Virus Infections | Lentivirus Infections | Tuberculosis, Pulmonary | Human Immunodeficiency Virus | HIV Coinfection | Aids/Hiv Problem

Russian Federation
University of California, San Diego
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Obstructive Sleep Apnea Endotypes and Impact on Phenotypes of People Living With HIV (PLWH/OSA)

Obstructive Sleep Apnea | Human Immunodeficiency Virus

United States
CENTOGENE GmbH Rostock

Withdrawn

Biomarker for Cystinosis Disease: BioCystinosis (BioCystinosis) (BioCystinosis)

Hypophosphatemia | Photophobia | Renal Fanconi Syndrome

Germany, India, Sri Lanka
National Cancer Institute (NCI)

Terminated

A Phase II Trial of the DNA Methyl Transferase Inhibitor, Guadecitabine (SGI-110), in Children and Adults With Wild Type GIST,Pheochromocytoma and Paraganglioma Associated With Succinate Dehydrogenase Deficiency and HLRCC-associated Kidney Cancer

Carcinoma, Renal Cell | Gastrointestinal Stromal Tumors | Pheochromocytoma | Paraganglioma | Renal Neoplasms

United States
Baxalta now part of Shire

Completed

Safety and Efficacy Study of a 10% Intravenous Immune Globulin Solution in Subjects With Primary Immunodeficiency Disorders

Primary Immunodeficiency Diseases (PID) | Immune Thrombocytopenic Purpura (ITP) | Kawasaki Syndrome

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Fludarabine Phosphate, Cyclophosphamide, and Total-Body Irradiation Followed by Donor Bone Marrow Transplant, Mycophenolate Mofetil, and Cyclosporine in Treating Patients With Fanconi Anemia

Previously Treated Myelodysplastic Syndrome | Fanconi Anemia | de Novo Myelodysplastic Syndrome | Acute Myeloid Leukemia in Remission

United States, Brazil
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Retrovirus Epidemiology Donor Study-II (REDS-II)

HIV Infections | Acquired Immunodeficiency Syndrome | Retroviridae Infections | Hepatitis B | Hepatitis, Viral, Human | Blood Transfusion | HIV-1 | Blood Donors | Hepacivirus | HIV-2 | HTLV-I | HTLV-II | West Nile Virus
Xiaofan Zhu

Available

Use Massive Parallel Sequencing and Exome Capture Technology to Sequence the Exome of Fanconi Anemia Children and Their Patents

Fanconi Anemia | Autosomal or Sex Linked Recessive Genetic Disease | Bone Marrow Hematopoiesis Failure, Multiple Congenital Abnormalities, and Susceptibility to Neoplastic Diseases. | Hematopoiesis Maintainance.

China
NeurogesX

Terminated

An Open-Label Extension Study of NGX-4010 for the Treatment of Neuropathic Pain

HIV Infections | Pain | Diabetes Mellitus | Diabetic Neuropathies | Peripheral Nervous System Diseases | Neuralgia | Herpes Zoster | Polyneuropathies
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Unknown

NK Cells in Cord Blood Transplantation

Recurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Secondary Acute Myeloid Leukemia | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Recurrent Small Lymphocytic Lymphoma | Refractory Chronic Lymphocytic Leukemia | Recurrent Non-Hodgkin Lymphoma | Refractory Non-Hodgkin Lymphoma | Recurrent Acute Lymphoblastic Leukemia and other conditions

United States
National Taiwan University Hospital

Unknown

The Role of Apoptosis Associated Markers in Pathogenesis of Pulmonary Tuberculosis

To Compare the Serum Apoptosis-associated Markers Between Patients With Active TB and Patients With LTBI | To Evaluate the Efficiency of Apoptosis-associated Markers to Differentiate Potential of Active TB From LTBI

Taiwan
Cambridge Health Alliance
The Thoracic Foundation; Alturix

Not yet recruiting

NAC for Attenuation of COVID-19 Symptomatology (NACinCOVID2)

Covid19 | Oxidative Stress | SARS-CoV2 Infection | COVID-19 Pneumonia | SARS-CoV-2 Acute Respiratory Disease | COVID-19 Respiratory Infection | SARS-Associated Coronavirus as Cause of Disease Classified Elsewhere | COVID-19 Lower Respiratory Infection

United States
University Hospital, Bonn

Unknown

Incidence and Effects of Sleep Apnea on Intracerebral Aneurysms (IESA)

Comorbidities | Sleep Apnea (Defined as Apnea Hypopnea Index > 5/h) | Intracranial Aneurysm Size | Blood Pressure Medication | Complications (Subarachnoid Hemorrhage)

Germany
Latin American Cooperative Oncology Group

Recruiting

A Global Record of Patients With Anal Squamous Cell Carcinoma With and Without HIV Infection (ACTION HIV)

HIV Infections | Anal Squamous Cell Carcinoma

Brazil
National Medical Research Center for Rehabilitation...
Pirogov Russian National Research Medical University; DNKOM LLC; The Orenburg...

Recruiting

Study of Efficacy and Safety of the Plasmapheresis Method With Albumin Compensation Compared With the Plasmapheresis Method Without Albumin Compensation for Aging Biomarkers Correction in Men and Women Aged 40 to 55 Years Old

Cardiovascular Diseases | Nervous System Diseases | Urologic Diseases | Diabetes | Neuromuscular Diseases | Hypercholesterolemia | Gout | Hyperbilirubinemia | Hyper IgE Syndrome | Hyper-LDL-cholesterolemia | Hyper Beta Lipoproteinemia | Hyper Eosinophilic Syndrome

Russian Federation
Foundation for Professional Development (Pty) Ltd
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Recruiting

Clinical Study of STI Screening to Prevent Adverse Birth and New-born Outcomes

HIV/AIDS | Pregnancy | Cost-effectiveness | Antenatal Care | Chlamydia Trachomatis | Vaginal Microbiome | Birth Outcomes | Sexually Transmitted Infection | Neisseria Gonorrhoeae | Trichomonas Vaginalis

South Africa
National Cancer Institute (NCI)

Recruiting

Molecular Characterization of Viral-associated Tumors, Tumors Occurring in the Setting of HIV or Other Immune Disorders and Castleman Disease

Kaposi's Sarcoma | Human Immunodeficiency Virus | Castleman's Disease | Viral-Associated Cancer

United States
Massachusetts General Hospital

Recruiting

Kisspeptin Administration in the Adult

PCOS | Kallmann Syndrome | Hypogonadotropic Hypogonadism | Polycystic Ovarian Syndrome | Hyperprolactinemia | GnRH Deficiency

United States
AbbVie

Completed

A Study to Evaluate the Efficacy and Safety of Experimental Drugs ABT- 493/ABT-530 in Adults With Chronic Hepatitis C Virus Genotype 1-6 Infection and Human Immunodeficiency Virus -1 Coinfection (EXPEDITION-2) (EXPEDITION-2)

Hepatitis C Virus Infection | Chronic Hepatitis C | Human Immunodeficiency Virus Infection | Compensated Cirrhosis and Non-cirrhotics
AbbVie

Completed

A Multipart, Open-label Study to Evaluate the Safety and Efficacy of ABT-450/r/ABT-267 With and Without ABT-333 Coadministered With and Without Ribavirin in Adult With Genotype 1 or 4 Hepatitis C Virus (HCV) Infection and Human Immunodeficiency Virus, Type 1 Coinfection (TURQUOISE-I)

Hepatitis C Virus Infection | Chronic Hepatitis C | Human Immunodeficiency Virus Infection | Compensated Cirrhosis and Non-cirrhotics
Kirby Institute
National Institute of Allergy and Infectious Diseases (NIAID); ViiV Healthcare and other collaborators

Withdrawn

Inflammation and Co-Infections in D²EFT (i2-D²EFT)

Cytomegalovirus Infections | Human Papilloma Virus | HIV-infection/Aids | Human Herpesvirus 4 Infections | Human Herpesvirus 8 Infection
Vanderbilt University
National Heart, Lung, and Blood Institute (NHLBI); University of South Florida and other collaborators

Completed

A Longitudinal Study of Hermansky-Pudlak Syndrome Pulmonary Fibrosis

Hermansky Pudlak Syndrome

United States
Jesse Roman
Genentech, Inc.

Unknown

Efficacy and Safety of Pirfenidone Treatment in HPS-ILD (PEARL)

Interstitial Lung Disease | Hermansky Pudlak Syndrome

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...

Withdrawn

Medical Treatment of Colitis in Patients With Hermansky-Pudlak Syndrome

Colitis | Cytokines | Hermanski-Pudlak Syndrome | Lymphocytes | Drug Evaluation

United States
University Hospital, Basel, Switzerland
Bristol-Myers Squibb; Swiss National Science Foundation

Completed

Cardiovascular Risk Factor Management in HIV Infection

HIV Infection | Dyslipidemia | Coronary Heart Disease | Diabetes Mellitus, Non-Insulin-Dependent

Switzerland
National Human Genome Research Institute (NHGRI)

Terminated

Pilot Study of a Multi-Drug Regimen for Severe Pulmonary Fibrosis in Hermansky-Pudlak Syndrome

Pulmonary Fibrosis | Metabolic Disease | Oculocutaneous Albinism | Hermansky-Pudlak Syndrome (HPS) | Platelet Storage Pool Deficiency

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Personalized NK Cell Therapy in CBT

Recurrent Hodgkin Lymphoma | Chronic Myelomonocytic Leukemia | Previously Treated Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Secondary Acute Myeloid Leukemia | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Myelodysplastic Syndrome... and other conditions

United States
National Institute of Respiratory Diseases, Mexico
Hospital General Dr. Manuel Gea González; National Institute of Medical Sciences... and other collaborators

Not yet recruiting

Point of Care Tests to Identify Opportunistic Infections in Advanced HIV Patients in Mexico City (PREVALIOCDMX)

Acquired Immunodeficiency Syndrome | Cryptococcal Meningitis | Tuberculosis Infection | Histoplasmosis AIDS

Mexico
SphinCS Lyso Gemeinnutzige UG (Haftungsbeschrankt)

Recruiting

Registry Gangliosidoses

Gangliosidoses | Galactosialidosis | Sialidosis | GM1 Gangliosidosis | Tay-Sachs Disease | Sandhoff Disease | Morquio B Disease | Gm2-Gangliosidosis, Variant B1 | GM2 Activator Deficiency

Germany

Clinical Trials on ASS Deficiency

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Uzbekistan

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations