Clinical Trials on Access and Evaluation in United Kingdom

Total 161907 results

Mannkind Corporation

Completed

A Study Designed to Determine if the Drugs Albuterol (Salbutamol) and Fluticasone Have an Effect on the Pharmacokinetics of the Investigational Product Technosphere® Insulin Inhalation Powder in Healthy Volunteers

Diabetes Mellitus | Healthy Subjects

United Kingdom
University of Virginia
AstraZeneca

Completed

Determine the Safety/Efficacy of Ticagrelor for Maintaining Patency of Arterio-Venous Fistulae Created for Hemodialysis

End Stage Renal Disease | Vascular Access Patency

United States
Masonic Cancer Center, University of Minnesota

Recruiting

Hematopoietic Stem Cell Transplantation in the Treatment of Infant Leukemia

Myelodysplastic Syndromes | Leukemia | Previously Treated Myelodysplastic Syndrome | Secondary Acute Myeloid Leukemia | Childhood Acute Myeloid Leukemia in Remission | Childhood Acute Lymphoblastic Leukemia in Remission | Recurrent Childhood Acute Myeloid Leukemia | Secondary Myelodysplastic Syndrome and other conditions

United States
St. Louis University

Completed

Utility of Trimethoprim-sulfamethoxazole Use in Skin Abscess Management

Skin Diseases, Infectious

United States
National Institute of Allergy and Infectious Diseases...

Completed

Primary Prophylaxis of Cerebral Toxoplasmosis in HIV-Infected Patients

HIV Infections | Toxoplasmosis, Cerebral

United States
United States Naval Medical Center, San Diego

Completed

Auricular Acupuncture for The Treatment of Post-Tonsillectomy Pain

Obstructive Sleep Apnea | Peritonsillar Abscess | Recurrent Tonsillitis

United States
University of Washington
National Cancer Institute (NCI)

Completed

Early Allogeneic Hematopoietic Cell Transplantation in Treating Patients With Relapsed or Refractory High-Grade Myeloid Neoplasms

Previously Treated Myelodysplastic Syndrome | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Myelodysplastic Syndrome With Excess Blasts-2 | Myeloid Neoplasm | Chronic Myelomonocytic Leukemia-2 | Blasts 10 Percent or More of Bone Marrow Nucleated... and other conditions

United States
CryoLife, Inc.

Completed

Post-market, Prospective Evaluation of PHOTO-oxidized Bovine Pericardium in Vascular Surgery (PHOTO-V)

Vascular Diseases | Peripheral Arterial Disease | Carotid Artery Diseases | Abdominal Aortic Aneurism | Hemodialysis Access Failure (Disorder)

United States
Case Western Reserve University
National Eye Institute (NEI); Jaeb Center for Health Research

Completed

Cornea Preservation Time Study (CPTS)

Cornea Preservation Time | Endothelial Keratoplasty | Transplant Success | Endothelial Cell Density

United States
Imperial College London

Enrolling by invitation

Smart Watch Insights for Prevention of Exacerbations and Enhance Rehabilitation - Movement Study (SWIPER-MOVES)

Cardiovascular Diseases | Diabetes | Respiratory Disease | Non-Alcoholic Fatty Liver Disease

United Kingdom
University of Illinois at Urbana-Champaign
University of Houston; University of Puerto Rico; Iowa State University; California...

Unknown

Abriendo Caminos 2: Clearing the Path to Hispanic Health

Obesity | Childhood Obesity | Nutrient; Excess | Community Health Education

United States, Puerto Rico
Infectopharm Arzneimittel GmbH
INPADS GmbH; Dr. Oestreich + Partner GmbH

Recruiting

Fosfomycin i.v. for Treatment of Severely Infected Patients (FORTRESS)

Respiratory Tract Infections | Sepsis | Encephalitis | Bacterial Infections | Intraabdominal Infections | Bacteremia | Skin Diseases, Bacterial | Pneumonia, Bacterial | Urinary Tract Infections | Meningitis, Bacterial | Central Nervous System Bacterial Infections | Soft Tissue Infections | Endocarditis, Bacterial | Bone Diseases, Infectious and other conditions

Germany, Austria, Greece, Italy, United Kingdom
Rhode Island Hospital

Completed

Soft Tissue Ultrasound of Infections

Abscess | Cellulitis | Soft Tissue Infections

United States
National Cancer Institute (NCI)

Recruiting

Venetoclax in Combination With ASTX727 for the Treatment of Chronic Myelomonocytic Leukemia and Other Myelodysplastic Syndrome/Myeloproliferative Neoplasm

Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome | Myelodysplastic Syndrome With Excess Blasts | Myeloproliferative Neoplasm

United States, Canada
University of Washington
National Institute on Aging (NIA)

Recruiting

Promoting Goals-of-Care Discussions for Patients With Memory Problems and Their Caregivers (PICSI-M)

Liver Cirrhosis | Quality of Life | Neoplasm Metastasis | Pulmonary Disease, Chronic Obstructive | Peripheral Vascular Diseases | Dementia | Kidney Failure, Chronic | Chronic Disease | Lung Diseases, Interstitial | Health Communication | Lung Neoplasm | Heart Failure，Congestive | Patient Care | Health Care Quality... and other conditions

United States
Vascular Therapies, Inc.

Recruiting

A Study Testing the Use of a Perivascular Sirolimus Formulation (Sirogen) in ESRD Patients Undergoing AV Fistula Surgery (ACCESS2)

End Stage Renal Disease | ESRD | End Stage Kidney Disease | Arteriovenous Fistula | Vascular Access Complication | Chronic Kidney Failure | Complication of Hemodialysis | Complication of Renal Dialysis

United States, United Kingdom
CardioKine Inc.
Biogen; Cardiokine Biopharma, LLC

Completed

International, Multicenter Study of a Twenty-eight Week, Open-label, Titrated Oral Lixivaptan Administration in Patients With Chronic Hyponatremia: Extension to Studies CK-LX3401, 3405, and 3430

Hyponatremia With Excess Extracellular Fluid Volume | Hyponatremia With Normal Extracellular Fluid Volume

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Yttrium-90 Anti-CD45 Monoclonal Antibody BC8 Followed by Donor Stem Cell Transplant in Treating Patients With High-Risk AML, ALL, or MDS

Chronic Myelomonocytic Leukemia | Previously Treated Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Secondary Acute Myeloid Leukemia | Recurrent Adult Acute Lymphoblastic Leukemia | Refractory Anemia With Excess Blasts

United States
M.D. Anderson Cancer Center

Recruiting

A Phase II Study of Cladribine and Low Dose Cytarabine in Combination With Venetoclax, Alternating With Azacitidine and Venetoclax, in Patients With Higher-risk Myeloproliferative Chronic Myelomonocytic Leukemia or Higher-risk Myelodysplastic Syndromes With Excess Blasts

Myelodysplastic Syndromes | Myeloproliferative Chronic Myelomonocytic Leukemia

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Fludarabine Phosphate, Cytarabine, Filgrastim-sndz, Gemtuzumab Ozogamicin, and Idarubicin Hydrochloride in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Untreated Adult Acute Myeloid Leukemia | Myelodysplastic Syndrome With Excess Blasts | High Risk Myelodysplastic Syndrome | de Novo Myelodysplastic Syndrome | Acute Myeloid Leukemia With t(8;21); (q22; q22.1); RUNX1-RUNX1T1 | Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11 | Acute Myeloid... and other conditions

United States
National Cancer Institute (NCI)

Completed

PS-341 in Treating Patients With Refractory or Relapsed Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myeloid Leukemia in Blast Phase, or Myelodysplastic Syndrome

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Promyelocytic Leukemia (M3) | Previously Treated Myelodysplastic Syndromes | Recurrent Adult Acute Lymphoblastic Leukemia | Relapsing Chronic Myelogenous Leukemia | Refractory Anemia With Excess Blasts | Blastic Phase Chronic Myelogenous Leukemia and other conditions

United States
Galderma R&D

Completed

Evaluate Effectiveness of Epiduo® Gel in Reducing Antibiotic Sensitive & Resistant Strains of Propionibacterium (P)Acnes

P Acnes Colonization

United States
The Cleveland Clinic

Completed

Effectiveness of Creatine in Preventing Muscle Aching From Cholesterol-Lowering Statin Drugs

Hypercholesterolemia | Weakness | Cramps | Aches

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Randomized Prospective Study of Pyrimethamine Therapy for Prevention of Toxoplasmic Encephalitis in HIV-Infected Individuals With Serologic Evidence of Latent Toxoplasma Gondii Infection

HIV Infections | Toxoplasmosis, Cerebral

United States
Lucy Holmes, MD
Women & Children's Hospital of Buffalo; New York State Department of Health

Completed

Evaluation of 3 Versus 10 Days of Antibiotics in Skin Abscesses After Surgical Drainage

Abscess | Skin Disease, Bacterial

United States
Vanderbilt University Medical Center
UCB Pharma

Completed

Study to Look at Benefit of Surgical Drainage Before Beginning Medical Therapy for Crohns Perianal Fistulas

Fistula | Abscess | Crohns Disease

United States
National Cancer Institute (NCI)

Completed

BMS-214662 in Treating Patients With Acute Leukemia, Myelodysplastic Syndrome, or Chronic Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Promyelocytic Leukemia (M3) | Childhood Myelodysplastic Syndromes | Previously Treated Myelodysplastic Syndromes | Recurrent Adult Acute Lymphoblastic Leukemia | Recurrent Childhood Acute Lymphoblastic Leukemia | Recurrent Childhood Acute Myeloid... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Hu8F4 in Treating Patients With Advanced Hematologic Malignancies

Hematopoietic and Lymphoid Cell Neoplasm | Myelofibrosis | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Secondary Acute Myeloid Leukemia | Recurrent Acute Myeloid Leukemia | Recurrent Chronic Myelomonocytic Leukemia | Refractory Chronic Myelomonocytic Leukemia | High Risk... and other conditions

United States
The Touro College and University System
University of Vienna; Osato Research Institute; University of Mauritius; Mauritius... and other collaborators

Completed

Molecular and Clinical Effects of Green Tea and Fermented Papaya Preparation on Diabetes and Cardiovascular Diseases

Assess the Effect of Green Tea on Diabetes | Assess the Effect of Fermented Papaya Pretration on Diabetes | Effects of Green Tea and FPP on C-reactive Proteins | Effects of Green Tea and FPP of Lipid Profiles in Diabetes | Effect of Green Tea and FPP on Atheroma Formation

Austria, Mauritius, United States
University of Leeds
Merck Sharp & Dohme LLC; Celgene; Amgen

Unknown

Use of Thalidomide, Lenalidomide, Carfilzomib, Bortezomib and Vorinostat in the Initial Treatment of Newly Diagnosed Multiple Myeloma Patients (Myeloma XI)

Multiple Myeloma

United Kingdom
University of Manchester

Completed

A Self-management Intervention for Adult Patients With Hearing Difficulties to Promote Hearing Aid Use and Benefit

Written Information | Written Info and Hearing Aid Reminder | Written Info and Planning on Hearing Aid Use | All Materials

United Kingdom
Melinta Therapeutics, Inc.

Completed

Oritavancin Versus IV Vancomycin for the Treatment of Participants With Acute Bacterial Skin and Skin Structure Infection (SOLO I) (SOLO I)

Abscess | Cellulitis | Wound Infection | Systemic Inflammation

United States
Melinta Therapeutics, Inc.

Completed

Oritavancin Versus IV Vancomycin for the Treatment of Patients With Acute Bacterial Skin and Skin Structure Infection (SOLO II)

Abscess | Cellulitis | Wound Infection | Systemic Inflammation

United States
Brentwood Biomedical Research Institute

Completed

Rapid Identification of Key Pathogens in Wound Infection by Molecular Means

Postoperative Wound Infection | Traumatic Wound Infection | Closed Soft Tissue Abscess

United States
University of Oxford

Completed

A Study Investigating Ways to Make Local Anaesthetic Hand Surgery Less Painful - Reducing Tourniquet Associated Pain (ReTAP)

Hand Injuries/Disease Requiring Surgery to the Hand

United Kingdom
Imperial College London
National Institute for Health Research, United Kingdom

Completed

Splinting to Treat Hand Osteoarthritis (SPLINTOA)

Hand Osteoarthritis

United Kingdom
Chelsea and Westminster NHS Foundation Trust

Unknown

The Effects of Electronic Cigarettes on the Microcirculation of the Hand

Hand Injuries | Elective Hand Surgery

United Kingdom
Prexton Therapeutics

Completed

A Phase I, Double Blind, Placebo Controlled, First in Human, Single and Multiple Ascending Oral Dose, Safety, Tolerability and Pharmacokinetic Study in Healthy Male and Female Subjects

Parkinson's Disease

United Kingdom
Mid Cheshire Hospitals NHS Foundation Trust

Withdrawn

Surgical Versus Conservative Treatment of Acute Mallet Fingers; a Randomised Controlled Trial

Finger Injury

United Kingdom
Imperial College Healthcare NHS Trust

Completed

Standard Versus Prolonged-release Tacrolimus Monotherapy After Alemtuzumab Induction in Kidney Transplantation (TAESR)

Graft Rejection | End-stage Renal Failure

United Kingdom
Hull University Teaching Hospitals NHS Trust
University of Hull

Completed

A Study of Routine Versus Selective Use of Ultrasound Scanning Prior to Haemodialysis Fistula Surgery

Surgery | End Stage Renal Failure

United Kingdom
Moorfields Eye Hospital NHS Foundation Trust

Completed

Dual Wavelength OCT

Retinal Degeneration | Diabetic Retinopathy | Retinal Dystrophies | AMD

United Kingdom
St George's, University of London
Rosetrees Trust

Completed

Pain Management in Osteoarthritis Using the Centrally Acting Analgesics Duloxetine and Pregabalin (DUPRO)

Hand Osteoarthritis

United Kingdom
Cambridge University Hospitals NHS Foundation Trust

Completed

Trial Comparing the Incidence of Steal Syndrome in the Two Types of anTEcubitaL Fossa Arteriovenous fistuLa AVF (STEAL)

Steal Syndrome | Arteriovenous Fistulas | Renal Failure, End-Stage

United Kingdom
University of Manchester

Unknown

Supporting Family Carers to People Living With Symptoms of Dementia at Home up to the End of Life

Family Caregivers

United Kingdom
Imperial College London
National Institute for Health Research, United Kingdom; Imperial College Healthcare...

Withdrawn

MRI Assessment of Myocardial Fibrosis Associated With Monocyte Phenotype in End Stage Renal Failure (CM3)

Myocardial Fibrosis | Heart Failure | End Stage Renal Failure on Dialysis | Chronic Kidney Disease Stage V | Chronic Kidney Disease, Stage IV (Severe)

United Kingdom
King's College Hospital NHS Trust
King's College London

Completed

Glycaemic Response to Oral Nutrition Support During Haemodialysis (GRO-HD)

Diabetes | Chronic Kidney Disease | End Stage Renal Failure on Dialysis

United Kingdom
Emma Aitken

Unknown

A Trial of Interrupted vs Continuous Suturing Techniques for Radiocephalic Fistulae

End Stage Renal Failure

United Kingdom
Imperial College Healthcare NHS Trust
National Institute for Health Research, United Kingdom

Completed

Effects of Oral Sodium Bicarbonate Supplementation in Haemodialysis Patients (BicHD) (BicHD)

End-stage Renal Disease

United Kingdom
Eunice Kennedy Shriver National Institute of Child...

Recruiting

Safety and Efficacy of Pegvisomant in Children With Growth Hormone Excess

Pituitary Disease

United States

Clinical Trials on Access and Evaluation in United Kingdom

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