Clinical Trials on Actinomycetales Infections

Total 56526 results

GlaxoSmithKline

Completed

Safety and Immunogenicity of GSK Biological's Candidate Tuberculosis Vaccine Mtb72F/AS02 in Healthy PPD-negative Adults.

Tuberculosis (TB)

Belgium
Thomas Schon
Karolinska University Hospital; University Hospital, Linkoeping

Completed

The Role of Therapeutic Drug Monitoring in Tuberculosis - a Pilot Study

Active Tuberculosis

Sweden
University of Oxford
Imaxio

Completed

Phase I Trial Evaluating Safety and Immunogenicity of MVA85A-IMX313 Compared to MVA85A in BCG Vaccinated Adults

Tuberculosis (TB)

United Kingdom
Pfizer

Completed

Bioequivalence Study Comparing Rifampicin In A Fixed-Dose Combination (Rifampicin+Isoniazid, Myrin© 2) And The Reference Drug (Rifampicin, Rimactane®)

Tuberculosis

Philippines
Mayo Clinic

Completed

Mycobacterium Avium Intracellulare Complex (MAC) Study (MAC)

Mycobacterium Avium Intracellulare Complex (MAC)

United States
Radboud University Medical Center

Recruiting

A Prospective, Multicenter, Single-arm MAC-PD Cohort: a NTM-NET and ESGMYC Collaborative Study (MAC-PD cohort)

Mycobacterium Avium Complex Pulmonary Disease

Korea, Republic of, United States, Croatia, Japan, Netherlands
National Hospital Organization Minami Kyoto Hospital

Completed

Energy Metabolism for the Patients With Pulmonary Mycobacterium Avium Complex

Emaciation | Energy Metabolism | Pulmonary MAC

Japan
Paratek Pharmaceuticals Inc

Active, not recruiting

Oral Omadacycline vs. Placebo in Adults With NTM Pulmonary Disease Caused by Mycobacterium Abscessus Complex (MABc)

Mycobacterium Infections, Nontuberculous | Nontuberculous Mycobacterial Lung Disease | Mycobacterium Abscessus Infection | Nontuberculous Mycobacterial Pulmonary Infection

United States
Shanghai Pulmonary Hospital, Shanghai, China
Karolinska Institutet; Fudan University; University of Sydney; Shanghai Municipal...

Recruiting

Drug Exposure and Minimum Inhibitory Concentration in the Treatment of MAC Lung Disease

Gram-Positive Bacterial Infections | Mycobacterium Infections | Mycobacterium Avium-Intracellulare Infection | Mycobacterium Avium Complex

China
Tuberculosis Research Centre, India
National Institutes of Health (NIH)

Recruiting

Comorbidities and Coinfections in Latent TB (COMBINE-TB)

Malnutrition | Latent Tuberculosis | Diabete Mellitus | Helminth Infection

India
University of California, San Francisco
Johns Hopkins University; National Institute of Allergy and Infectious Diseases... and other collaborators

Recruiting

Rapid Research in Diagnostics Development for TB Network (R2D2 Kids) and Assessing Diagnostics At POC for TB in Children (ADAPT for Kids)

Tuberculosis | Diagnostics | Global Health

Mozambique, South Africa, Uganda
Makerere University

Recruiting

Pharmacogenetics-guided Isoniazid Dosing in TB-HIV (PHINX)

Tuberculosis

Uganda
Boston University
Harvard Medical School (HMS and HSDM); University of Colorado, Denver; National... and other collaborators

Recruiting

Efficacy and Tolerability of Bedaquiline, Delamanid, Levofloxacin, Linezolid, and Clofazimine to Treat MDR-TB (DRAMATIC)

Tuberculosis, Multidrug-Resistant

Philippines, Vietnam
Cornell University
Arogyavaram Medical Centre

Not yet recruiting

Vitamin D Supplementation and TB

Tuberculosis | Immunity | Vitamin D

United States, India
Boston Medical Center
Boston University; National Institute of Allergy and Infectious Diseases (NIAID) and other collaborators

Enrolling by invitation

Transmission of Tuberculosis Among Illicit Drug Use Linkages (TOTAL)

Tuberculosis | Illicit Drug Use

South Africa
Centre for the AIDS Programme of Research in South...

Terminated

The Individualized M(X) Drug-resistant TB Treatment Strategy Study (InDEX)

Tuberculosis, Multidrug-Resistant

South Africa
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

High-Dose Isoniazid Among Adult Patients With Different Genetic Variants of INH-Resistant Tuberculosis (TB)

Tuberculosis

Haiti, South Africa
Green Cross Corporation

Completed

A Study of GC3107(BCG Vaccine) in Healthy Infants

Tuberculosis | BCG Vaccination Reaction

Korea, Republic of
Otsuka Pharmaceutical Development & Commercialization...

Completed

A Trial to Evaluate Safety, Tolerability, and Efficacy of Orally Administered OPC-67683

Tuberculosis, Multidrug-Resistant

Korea, Republic of, China, Estonia, Latvia, Peru, Philippines
Liverpool School of Tropical Medicine
London School of Hygiene and Tropical Medicine; University of Liverpool; Malawi-Liverpool-Wellcome...

Terminated

Male Partner-assisted Contact Tracing for HIV and Tuberculosis in Malawi (mPATCH-TB)

Tuberculosis

Malawi
Aeras
Sanofi Pasteur, a Sanofi Company; Statens Serum Institut; HIV Vaccine Trials...

Completed

Safety and Immunogenicity Study of BCG, H4:IC31, and H56:IC31 Revaccination in Healthy Adolescents

Tuberculosis

South Africa
University Medical Center Groningen

Unknown

Feasibility of Centralized Therapeutic Drug Monitoring of Fluoroquinolones in Multi-Drug Resistant Tuberculosis Patients (PERFECT)

Tuberculosis, Multidrug-Resistant

Sweden, United Kingdom, Australia, Belarus, Brazil, Greece, Italy, Latvia, Mexico, Netherlands, Portugal, South Africa, Tanzania
GlaxoSmithKline

Completed

Safety and Immunogenicity of a Candidate Tuberculosis (TB) Vaccine in HIV-positive Adults.

Tuberculosis

Switzerland
Serum Institute of India Pvt. Ltd.
University of Stellenbosch; South African Tuberculosis Vaccine Initiative; Vakzine... and other collaborators

Completed

Study to Evaluate the Safety and Immunogenicity of VPM1002 in Comparison With BCG in HIV-exposed/-Unexposed Newborn Infants in South Africa

Tuberculosis

South Africa
Aeras
National Institute of Allergy and Infectious Diseases (NIAID); Sanofi Pasteur... and other collaborators

Completed

Phase 1/II, Safety and Immunogenicity Study of AERAS-404 in BCG-Primed Infants (C-015-404)

Tuberculosis

South Africa
Brigham and Women's Hospital
National Institute of Allergy and Infectious Diseases (NIAID); Bill and Melinda... and other collaborators

Completed

Operational Assessment of Laboratory Information System for MDR-TB in Lima, Peru

Tuberculosis, Multidrug-Resistant

Peru
Johns Hopkins University

Completed

Chepetsa TB - Reducing TB Among HIV-Infected Malawians

Tuberculosis

Malawi
Aeras
University of Oxford; University of Cape Town

Completed

A Study of MVA85A in Healthy Infants

Tuberculosis

South Africa
All India Institute of Medical Sciences, New Delhi
Sanjay Gandhi Postgraduate Institute of Medical Sciences; Christian Medical...

Completed

Treatment Duration for Abdominal Tuberculosis (RNTCP-DOTS)

Tuberculosis

India
Statens Serum Institut

Completed

A Trial of the C-Tb Skin Test, When Given Intradermally to Adult Patients Recently Diagnosed With Active Tuberculosis (TB) (TESEC-04)

Tuberculosis

South Africa
University of California, San Diego
National Institute of Allergy and Infectious Diseases (NIAID); National Institutes...

Completed

Global Consortium for Drug-resistant Tuberculosis Diagnostics (GCDD)

Tuberculosis | Tuberculosis, Multidrug-Resistant

India, Moldova, Republic of, South Africa
Aeras

Completed

A Study to Evaluate Safety and Immunogenicity of AERAS-402

Tuberculosis

India
Aeras
Statens Serum Institut

Completed

A Phase I Study to Evaluate Safety and Immunogenicity of AERAS 404 Administered in Adults

Tuberculosis

Finland
Asan Medical Center

Completed

Isoniazid (INH) Treatment Based on ELISPOT Assay

Kidney Transplant Recipient

Korea, Republic of
University of Cape Town

Completed

Utility of Sputum Induction and Novel Technologies to Improve TB Diagnosis in a High HIV Prevalence Primary Care Setting (SINET)

Tuberculosis

South Africa
Dignitas International
University of Toronto; Ministry of Health and Population, Malawi

Completed

A Knowledge Translation Intervention for TB/HIV Treatment Adherence, in Zomba District, Malawi

Tuberculosis

Malawi
Harvard School of Public Health (HSPH)
Muhimbili University of Health and Allied Sciences

Completed

Nutrition, Immunology and Epidemiology of Tuberculosis

Tuberculosis

United States
Centers for Disease Control and Prevention
US Department of Veterans Affairs

Completed

TBTC Study 25PK: Intensive Pharmacokinetic Study of Three Doses of Rifapentine and 25-Desacetyl Rifapentine

Tuberculosis

United States, Canada
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Study of a Single Dose of Pretomanid Added to an Optimized Background Regimen in Children With Rifampicin-Resistant Tuberculosis

Tuberculosis | Rifampicin Resistant Tuberculosis

Brazil, India, South Africa, Tanzania, Thailand
University of Cape Town
University of Stellenbosch; University of Cape Town Lung Institute; Ospedale... and other collaborators

Not yet recruiting

Test to Treat TB: Impact of Sputum Sequencing-guided Individualised Therapy on Outcomes in Drug-resistant Tuberculosis (T3-RCT)

Tuberculosis, Multidrug-Resistant

South Africa
Foundation for Innovative New Diagnostics, Switzerland
Universidad Peruana Cayetano Heredia; Kenya Medical Research Institute; V. N.... and other collaborators

Active, not recruiting

Bioneer IRONqPCR ™ RFIA Kit Kit Clinical Evaluation

Tuberculosis, Multidrug-Resistant

Kenya, Peru, Ukraine
Foundation for Innovative New Diagnostics, Switzerland

Completed

Clinical Evaluation of tNGS for Diagnosis of DR-TB (Seq&Treat)

Tuberculosis, Multidrug-Resistant

Georgia, India, South Africa
Western University of Health Sciences

Completed

Topical Absorption of Glutathione-cyclodextrin Complex in Healthy Human Subjects Improves Immune Response Against Mycobacterium Infection

Glutathione-cyclodextrin Complex Absorption

United States
Boston University
National Institute of Allergy and Infectious Diseases (NIAID); Centers for... and other collaborators

Completed

Efficacy and Safety of Levofloxacin for the Treatment of MDR-TB (Opti-Q)

Tuberculosis, Multidrug-Resistant

South Africa, Peru
Makerere University

Completed

Safety and Efficacy of High Dose Rifampicin in Tuberculosis (TB)-HIV Co-infected Patients on Efavirenz- or Dolutegravir-based Antiretroviral Therapy (SAEFRIF)

Tuberculosis

Uganda
Dissou AFFOLABI
London School of Hygiene and Tropical Medicine; World Health Organization; Institute... and other collaborators

Completed

DIAgnostics for Multidrug Resistant Tuberculosis in Africa (DIAMA)

Tuberculosis, Multidrug-Resistant

Belgium, Benin, Cameroon, Congo, The Democratic Republic of the, Ethiopia, Guinea, Mali, Nigeria, Rwanda, Senegal
Partners in Health
Harvard Medical School (HMS and HSDM); Epicentre; Interactive Research and Development and other collaborators

Completed

Expand New Drugs for TB [endTB]

Tuberculosis, Multidrug-Resistant

Georgia, Armenia, Bangladesh, Belarus, Ethiopia, Indonesia, Kazakhstan, Kenya, Kyrgyzstan, Lesotho, Myanmar, Pakistan, Peru, South Africa
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating PK, Tolerability, and Safety of Rifapentine and Isoniazid in Pregnant and Postpartum Women

Tuberculosis

Haiti, Kenya, Thailand, Malawi, Zimbabwe
National Institute of Allergy and Infectious Diseases...

Completed

A Cluster-Randomized Trial of DOTS vs DOTS Plus Active Case Finding

Mycobacterium Tuberculosis

Brazil
GlaxoSmithKline

Completed

Safety and Immunogenicity Study of a Candidate Tuberculosis Vaccine in Human Immunodeficiency Virus (HIV)-Positive Adults

Tuberculosis

India

Clinical Trials on Actinomycetales Infections

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Cyprus

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations