Clinical Trials on Acute Coronary Syndrome in South Africa

Total 2250 results

LLS PedAL Initiative, LLC
National Cancer Institute (NCI); Children's Oncology Group

Recruiting

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome | Myeloid Leukemia Associated With Down Syndrome | Mixed Phenotype Acute Leukemia | Acute Myeloid Leukemia Post Cytotoxic Therapy | Myelodysplastic Syndrome Post Cytotoxic Therapy

United States, Canada, Australia, Puerto Rico, New Zealand
Cardiovascular Research Society, Greece

Completed

Remote Ischemic Preconditioning in ad Hoc Percutaneous Coronary Interventions

Coronary Artery Disease

Greece
PENTA Foundation

Active, not recruiting

Early Anti-Retroviral Treatment in HIV- Infected Children

HIV Infections

South Africa, Mali, Mozambique
Desmond Tutu HIV Foundation
National Institute of Mental Health (NIMH); University of Pennsylvania; National...

Recruiting

Improving HIV Testing, Linkage, and Retention in Care for Men Through U=U Messaging

HIV Infections | Treatment Adherence | Men

South Africa
Forma Therapeutics, Inc.

Completed

Open-label Study of FT-2102 With or Without Azacitidine or Cytarabine in Patients With AML or MDS With an IDH1 Mutation

Acute Myeloid Leukemia | Myelodysplastic Syndrome | Acute Myelogenous Leukemia

United States, Spain, Korea, Republic of, Australia, Canada, Germany, France, United Kingdom, Italy
National Cancer Institute (NCI)

Completed

Tipifarnib in Treating Patients With Acute Myeloid Leukemia in Remission

Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia in Remission | Myelodysplastic Syndrome With Excess Blasts | Adult Acute Monocytic Leukemia | Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11 and other conditions

United States, Israel, Peru
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Monoclonal Antibody Plus Chemotherapy in Treating Young Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndromes

Myelodysplastic Syndromes | Leukemia

United States, Canada, Australia
Gilead Sciences

Active, not recruiting

Study to Evaluate the Pharmacokinetics, Safety, and Antiviral Activity of the Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (E/C/F/TAF) Single Tablet Regimen (STR) in HIV-1 Infected Antiretroviral Treatment-Naive Adolescents and Virologically Suppressed Children

HIV Infections | Acquired Immune Deficiency Syndrome (AIDS)

United States, Thailand, Uganda, South Africa, Zimbabwe
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Prolonged Enoxaparin In Primary Percutaneous Coronary Intervention; A Pilot Pharmacodynamic Study (PENNY PCI)

Primary Percutaneous Coronary Intervention

United Kingdom
Cardiovascular Research Society, Greece

Completed

Spot Drug-Eluting Stenting for Long Coronary Stenoses

Angioplasty

Greece
Abbott Medical Devices

Completed

SPIRIT II: A Clinical Evaluation of the XIENCE V® Everolimus Eluting Coronary Stent System (SPIRIT II)

Coronary Artery Disease | Coronary Disease | Coronary Restenosis

Netherlands, Spain, Denmark, Germany, France, Austria, Belgium, India, Italy, New Zealand, Poland, South Africa, Switzerland
Cardiovascular Research Society, Greece

Completed

Neutrophil Gelatinase-associated Lipocalin Concentration in Coronary Artery Disease

Coronary Artery Disease | Atherosclerosis

Greece
National Cancer Institute (NCI)

Completed

Azacitidine With or Without Entinostat in Treating Patients With Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, or Acute Myeloid Leukemia

Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Chronic Myelomonocytic Leukemia | Previously Treated Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Secondary Acute Myeloid Leukemia | Untreated Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia... and other conditions

United States
Instituto Nacional de Ciencias Medicas y Nutricion...
University of Pennsylvania; University of Witwatersrand, South Africa; Case Western... and other collaborators

Unknown

Maraviroc (CCR5) Antagonism to Decrease the Incidence of the Immune Reconstitution Inflammatory Syndrome in HIV-Infected Patients (CADIRIS)

HIV Infections | HIV | Immune Reconstitution Inflammatory Syndrome

Mexico, United States, South Africa
The University of New South Wales

Completed

The Effect of Manuka Eye Drops on Tear Film Properties

Dry Eye Syndrome

Australia
The University of New South Wales

Completed

The Effect of Punctal Plugs on Tear Volume and Osmolality

Dry Eye Syndromes

Australia
University of California, San Francisco
Massachusetts General Hospital; Aga Khan University; University of Utah; Texas... and other collaborators

Completed

The Efficacy of the HIV/AIDS Symptom Management Manual

Acquired Immunodeficiency Syndrome | HIV

United States, Kenya, Puerto Rico, South Africa
National Institute of Allergy and Infectious Diseases...
National Institute on Drug Abuse (NIDA); Eunice Kennedy Shriver National Institute... and other collaborators

Completed

BufferGel and PRO 2000/5: Vaginal Gels to Prevent HIV Infection in Women

HIV Infections

United States, Malawi, South Africa, Zambia, Zimbabwe
Novartis Pharmaceuticals

Completed

A Phase Ib/IIb, Open-label, Multi-center, Study of Oral Panobinostat Administered With 5-Azacitidine (in Adult Patients With Myelodysplastic Syndromes (MDS), Chronic Myelomonocytic Leukemia (CMML), or Acute Myeloid Leukemia (AML).

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Chronic Myelomonocytic Leukemia

Belgium, Hungary, Spain, Germany, Canada, Switzerland, Thailand, Korea, Republic of, United Kingdom, Italy, Austria, Sweden, France, United States
International Partnership for Microbicides, Inc.

Completed

Trial to Assess the Continued Safety of and Adherence to a Vaginal Ring Containing Dapivirine in Women

Human Immunodeficiency Virus

Malawi, South Africa, Uganda, Zimbabwe
VA Office of Research and Development
The George Institute

Completed

Prevention of Serious Adverse Events Following Angiography (PRESERVE)

Coronary Artery Disease | Acute Renal Failure | Kidney Disease

United States, Australia, New Zealand, Malaysia
PENTA Foundation
Baylor College of Medicine; University Hospital Birmingham NHS Foundation Trust and other collaborators

Recruiting

DTG/3TC Fixed Dose Formulations for the Maintenance of Virological Suppression in Children With HIV Infection Aged 2 to <15 Years Old (D3 (Penta21))

HIV Infections

Spain, United Kingdom, Thailand, South Africa, Uganda
International Partnership for Microbicides, Inc.

Withdrawn

A Safety and Efficacy Trial of Dapivirine Vaginal Ring in Africa

HIV Infections

South Africa, Malawi, Rwanda, Zimbabwe
NeuroRx, Inc.

Recruiting

Inhaled ZYESAMI™ (Aviptadil Acetate) for the Treatment of Severe COVID-19 (AVICOVID-2)

SARS-CoV 2 | COVID | ARDS | Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS) | Dyspnea | ALI

United States
Gilead Sciences

Completed

Pharmacokinetics, Safety, and Efficacy of Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Disoproxil Fumarate Single Tablet Regimen (STR) in Adolescents

HIV Infections | Acquired Immunodeficiency Syndrome

United States, Thailand, South Africa
Center for International Blood and Marrow Transplant...
National Marrow Donor Program; Pediatric Blood and Marrow Transplant Consortium and other collaborators

Completed

Treosulfan/Fludarabine/Low Dose TBI as a Preparative Regimen for Children With AML/MDS Undergoing Allo HCT

Acute Myeloid Leukemia (AML) | Myelodysplastic Syndrome (MDS)

United States
HIV Vaccine Trials Network
National Institute of Allergy and Infectious Diseases (NIAID)

Not yet recruiting

Evaluating the Safety, Tolerability, and Pharmacokinetics of Monoclonal Antibodies in Healthy Participants (HVTN143)

HIV Infections

South Africa
BioCryst Pharmaceuticals

Terminated

A Long Term Safety Study of BCX9930 in Subjects With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Paroxysmal Nocturnal Hemoglobinuria | PNH

United Kingdom, Austria, South Africa
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Safety and Efficacy of Mipomersen in Patients With Severe Hypercholesterolemia on a Maximally Tolerated Lipid-Lowering Regimen and Who Are Not on Apheresis

Hypercholesterolemia | Coronary Heart Disease

South Africa, Germany, United States, United Kingdom, Canada, Czech Republic
National Institute of Allergy and Infectious Diseases...

Completed

Acute HIV Infection Observational Study

HIV Infections

United States, Malawi, South Africa, Tanzania, Uganda
GlaxoSmithKline

Completed

Eltrombopag Treatment of Thrombocytopenia in Subjects With Advanced Myelodysplastic Syndrome (MDS) or Secondary Acute Myeloid Leukemia After MDS (sAML/MDS)

Myelodysplastic Syndrome

Puerto Rico, United States, Taiwan, Germany, Denmark, Hong Kong, Korea, Republic of, France, United Kingdom, Italy, Brazil
Abbott Medical Devices

Completed

ABSORB EXTEND Clinical Investigation (ABSORB EXTEND)

Myocardial Ischemia | Coronary Artery Disease | Coronary Disease | Cardiovascular Disease | Coronary Restenosis | Coronary Artery Stenosis

Netherlands, Taiwan, China, New Zealand, Singapore, France, United Kingdom, Austria, Israel, Italy, Malaysia, India, Poland, Sweden, Spain, South Africa, Canada, Australia, Japan, Argentina, Brazil, Switzerland, Belgium, Denmark, Germany
Restem, LLC.

Completed

Umbilical Cord Lining Stem Cells (ULSC) in Patients With COVID-19 ARDS (ULSC)

Covid19 | Corona Virus Infection | ARDS | SARS-CoV Infection | Coronavirus

United States
National Institute of Allergy and Infectious Diseases...

Active, not recruiting

Randomized, Open Label Safety Trial of Dapivirine Vaginal Ring and Oral TRUVADA® Use in Pregnancy

HIV Infections

South Africa, Uganda, Malawi, Zimbabwe
Robocath
European Cardiovascular Research Center

Recruiting

Change History and Adopt a Robotic SolutioN for anGioplasty procedurE (CHANGE)

Coronary Disease

France, Italy, Poland, South Africa, Belgium, Germany
Kirby Institute
Chelsea and Westminster NHS Foundation Trust

Completed

The Intensive Pharmacokinetics Sub-study of Encore1 (ENCORE1-PK)

HIV Infection

Argentina, South Africa, Thailand, United Kingdom
HIV Prevention Trials Network

Completed

The ADAPT Study: Use of Emtricitabine and Tenofovir Disoproxil Fumarate for Pre-Exposure Prophylaxis (PrEP) (ADAPT)

HIV Infections

United States, South Africa, Thailand
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety and Immune Response to an HIV Vaccine Boost Following the Administration of Two HIV Vaccines, in HIV-Uninfected, Healthy Adults (Study Extension to HVTN 073/SAAVI 102)

HIV Infections

United States, South Africa
Australian and New Zealand Intensive Care Research...

Terminated

A Multi-centre Trial of an Open Lung Strategy Including Permissive Hypercapnia, Alveolar Recruitment and Low Airway Pressure in Patients With Acute Respiratory Distress Syndrome (PHARLAP)

Acute Respiratory Distress Syndrome

Australia, Ireland, United Kingdom, New Zealand, Saudi Arabia
Infraredx
Royal Adelaide Hospital; South Australian Health and Medical Research Institute

Completed

In Vitro and In Vivo Comparison Between Intravascular Ultrasound (IVUS) Systems (SAVOIR2)

Coronary Artery Disease

Australia
National Institute of Allergy and Infectious Diseases...

Completed

Safety and Drug Detection Study of Dapivirine Vaginal Ring and Oral TRUVADA® in Breastfeeding Mother-Infant Pairs

HIV Infections

South Africa, Uganda, Malawi, Zimbabwe
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Safety and Effectiveness of Lopinavir/Ritonavir in Individuals Who Have Failed Prior HIV Therapy

HIV Infections

Malawi, South Africa, India, Tanzania, Thailand
University of Pennsylvania
National Heart, Lung, and Blood Institute (NHLBI); University Medical Center... and other collaborators

Enrolling by invitation

PROSpect: Prone and Oscillation Pediatric Clinical Trial

Acute Respiratory Distress Syndrome in Children

United States, Netherlands, Israel, Thailand, New Zealand, United Kingdom, Australia, Brazil, Canada, China, India, Italy, Malaysia, United Arab Emirates, Spain
Australian and New Zealand Intensive Care Research...
The Alfred

Not yet recruiting

Trial of ECMO to De-Sedate, Extubate Early and Mobilise in Hypoxic Respiratory Failure (REDEEM)

Pneumonia | Extracorporeal Membrane Oxygenation | Mechanical Ventilation Complication | Hypoxemia | COVID-19 Respiratory Infection | Acute Respiratory Distress Syndrome Due to COVID-19

Australia, Germany
Massachusetts General Hospital
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Active, not recruiting

Mechanisms of Cardiac Dysfunction in HIV and the Effect of Statins: A Cardiac MRI Study

HIV Infections

United States, South Africa
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety of and Adherence to a Vaginal Matrix Ring Containing Dapivirine and Oral Emtricitabine/Tenofovir Disoproxil Fumarate in an Adolescent and Young Adult Female Population

HIV Infections

South Africa, Uganda, Zimbabwe
International Partnership for Microbicides, Inc.

Withdrawn

A Safety and Efficacy Trial of Dapivirine Vaginal Ring in Africa

HIV Infections

South Africa, Kenya, Malawi
Onconova Therapeutics, Inc.

Completed

Phase II Part 2 Expansion of Oral Rigosertib in Combination With Azacitidine

Acute Myeloid Leukemia | Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome

United States, France
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Detection of Residual Disease in Children Receiving Therapy for Acute Myeloid Leukemia or Myelodysplastic Syndrome

Myelodysplastic Syndromes | Leukemia

United States, Australia, Canada
BioCryst Pharmaceuticals

Terminated

BCX9930 for the Treatment of PNH in Subjects Not Receiving Other Complement Inhibitor Therapy (REDEEM-2)

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Malaysia, South Africa, Korea, Republic of

Clinical Trials on Acute Coronary Syndrome in South Africa

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