Clinical Trials on Acute Graft Rejection

Total 19985 results

University of Pennsylvania
National Institute on Drug Abuse (NIDA)

Completed

Efficacy of Drug and Risk Counseling Among Methadone Patients in Jakarta, Indonesia (JAKPRO)

HIV Risk Behaviors | Heroin Injection | Retention in Methadone Treatment

Indonesia
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Tacrolimus and Methotrexate With or Without Sirolimus in Preventing Graft-Versus-Host Disease in Young Patients Undergoing Donor Stem Cell Transplant for Acute Lymphoblastic Leukemia in Complete Remission

Childhood Acute Lymphoblastic Leukemia in Remission | Graft Versus Host Disease | B-cell Childhood Acute Lymphoblastic Leukemia | L1 Childhood Acute Lymphoblastic Leukemia | L2 Childhood Acute Lymphoblastic Leukemia | T-cell Childhood Acute Lymphoblastic Leukemia

United States, Canada, Australia
Natera, Inc.

Recruiting

Study for the Prediction of Active Rejection in Organs Using Donor-derived Cell-free DNA Detection (SPARO)

Complications | Transplant Rejection | Allograft Rejection

United States
Brigham and Women's Hospital
Alexion Pharmaceuticals

Terminated

Efficacy and Safety of Eculizumab for Treatment of Antibody-mediated Rejection Following Renal Transplantation

Antibody-mediated Rejection | Humoral Rejection

United States
Novartis Pharmaceuticals

Completed

Efficacy, Tolerability and Safety of Early Introduction of Everolimus, Reduced Calcineurin Inhibitors and Early Steroid Elimination Compared to Standard CNI, Mycophenolate Mofetil and Steroid Regimen in Paediatric Renal Transplant Recipients

Prevention of Acute Rejection in Paediatric Recipients of a Renal Transplant

Germany, United Kingdom, France, Italy, United States, Hungary, Norway, Spain, Argentina, Brazil, Poland, Sweden, Turkey
Eitan Medical
Thomas Jefferson University

Recruiting

Sorrel 25R Injector - Sorrel Clinical Study Protocol

Injection Site Irritation | Injection Site Reaction | Injection Site

United States
Masonic Cancer Center, University of Minnesota

Terminated

Monitoring of Immune and Microbial Reconstitution in (HCT) and Novel Immunotherapies

Cytokine Release Syndrome | Immune and Microbial Reconstitution | Systemic Viral Infection | Acute-graft-versus-host Disease | Chronic Graft-versus-host-disease | Recurrent Malignancy | Allogenic Related Donors | Cell Therapy/Immunotherapy Patients

United States
First Affiliated Hospital Xi'an Jiaotong University

Not yet recruiting

Study on the Serum Metabolic Markers and Early Complications After Allo-HSCT： Cohort Study

Acute Graft Versus Host Disease | Acute Kidney Injury | Stem Cell Transplant Complications | Major Adverse Cardiac Events
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI)

Unknown

Antithymocyte Globulin and Cyclosporine in Preventing Graft-Versus-Host Disease in Patients Undergoing Chemotherapy With or Without Radiation Therapy Followed By Donor Stem Cell Transplant for Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia

Leukemia | Graft Versus Host Disease

United States
Hospices Civils de Lyon

Completed

Determination of Risk Factors of Postpartum Urinary Retention (PAUR)

Postpartum Acute Urinary Retention

France
University Hospital Inselspital, Berne

Completed

Effects of Thoracic Epidural Anesthesia on Lower Urinary Tract Function

Urodynamics | Acute Urinary Retention

Switzerland
Radboud University Medical Center
Universitaire Ziekenhuizen KU Leuven

Completed

Pharmacokinetics of Posaconazole (Noxafil®) as Prophylaxis for Invasive Fungal Infections (PIRAÑA)

Acute Graft Versus Host Disease | Allogeneic Stem Cell Transplant | Acute Myeloid Leucaemia | Myelo Dysplastic Syndrome

Belgium, Netherlands
Stanford University
Kaiser Foundation Research Institute

Completed

Genome Transplant Dynamics: Non-invasive Sequencing-based Diagnosis of Rejection (GTD)

Lung Transplant Rejection | Cardiac Transplant Rejection

United States
Duke University
Bristol-Myers Squibb

Withdrawn

Lung Transplant Plasmapheresis/Belatacept/Carfilzomib for Antibody Mediated Rejection and Desensitization

Lung Transplant Rejection | Antibody-mediated Rejection
Muş Alparlan University
Ataturk University

Completed

Testing Different Methods of Intramuscular Injection

Satisfaction, Patient | Pain, Acute | Hematoma | Injection Fear | Injection Site Bruising

Turkey
Assistance Publique - Hôpitaux de Paris

Completed

Transgender, Silicone and Blood Smear (TSBS)

Injection; Complications, Sepsis | Injection Site Disorder | Injection Site Extravasation | Intentional Poisoning by Silicone

France
Gulsum Coskun

Active, not recruiting

Efficacy of Manuel Pressure and Local Cold Spray in Reducing Injection Pain in Pregnant Women

Pain, Acute | Injection Site | Injection Fear | Alloimmunisation in Pregnancy

Turkey
Medical University of Vienna

Recruiting

A Prospective Randomized Trial of ECP in Subclinical AMR (EXPORT-DSA)

Lung Transplant Rejection | Antibody-mediated Rejection

Austria
Rush University Medical Center
CareDx

Completed

Donor-Derived Cell-Free DNA for Surveillance in Simultaneous Pancreas and Kidney Transplant Recipients

Kidney Transplant Rejection | Pancreas Transplant Rejection

United States
Karolinska University Hospital
Sahlgrenska University Hospital, Sweden

Completed

Neuroinflammation and Cognitive Dysfunction After Orthopedic Surgery

Surgery | Acute Phase Reaction

Sweden
University of Rome Tor Vergata
University of Milan

Unknown

Erythrocyte-Mediated Drug Delivery for the Prevention of Stent Restenosis (TROY)

Atherosclerosis | Acute-Phase Reaction

Italy
Hikma Pharmaceuticals LLC

Completed

Generic Mycophenolate Mofetil Safety Study for Prophylaxis in de Novo Renal Transplant Patients in Jordan (MyOra-PASS)

Acute Transplant Rejection in Patients Receiving Allogeneic Renal Transplant

Jordan
CHU de Quebec-Universite Laval
Fédération des médecins résidents du Québec

Not yet recruiting

Prophylactic Use of Tamsulosin in the Prevention of Post-operative Urinary Retention in Men After Rectum Resection (R-POUR)

Colorectal Surgery | Urinary Retention | Post-operative Urinary Retention | Rectal Resection | Tamsulosin

Canada
Vanderbilt University Medical Center

Enrolling by invitation

Defining the Temporal Changes in the Acute Phase Response During Graded Exercise: A Prospective Study

Acute Phase Response

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Correlation Between Pre-transplant ICI Exposure and Post-transplant Graft Rejection

Hepatocellular Carcinoma | Graft Rejection | Immunotherapy | Immune Checkpoint Inhibitor

China
Washington University School of Medicine
Bristol-Myers Squibb; National Heart, Lung, and Blood Institute (NHLBI)

Completed

Belatacept Pilot Study in Lung Transplantation Immunosuppression in Lung Transplantation

Lung Transplant Rejection | Antibody-mediated Rejection

United States
Universitaire Ziekenhuizen KU Leuven
KU Leuven

Completed

Montelukast in Bronchiolitis Obliterans Syndrome (MLK002)

Bronchiolitis Obliterans | Graft Rejection | Lung Transplantation

Belgium
Hospital Vall d'Hebron

Completed

Human Microbiota and Liver Transplant

Infection | Intestinal Microbiota | Complication of Transplanted Liver | Acute Rejection of Liver Transplant

Spain
Molnlycke Health Care AB
Syntactx

Completed

Confirm the Safety and Performance of Avance Solo NPWT System (ASOLO-SW)

Acute Wound | Skin Graft | Skin Flap | Traumatic Wound | Dehiscence | Subacute Wound

Belgium, Italy, Germany, France
Massachusetts General Hospital
National Heart, Lung, and Blood Institute (NHLBI); Beth Israel Deaconess Medical... and other collaborators

Active, not recruiting

Circulating RNAs in Acute Congestive Heart Failure (CRUCiAL)

Heart Failure With Reduced Ejection Fraction | Heart Failure With Normal Ejection Fraction | Acute Congestive Heart Failure

United States
Neena Kapoor, M.D.

Not yet recruiting

TCRαβ/CD19 Depletion of Stem Cell Grafts for Transplant

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Hematologic Malignancy | Graft Vs Host Disease | Graft-versus-host-disease | Non-hematologic Malignancy
Juan Francisco Delgado Jimenez
Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III

Active, not recruiting

MuLtimodality EvaluatiOn of aNtibody mEdiated Damage in Heart Transplantation (LEONE-HT) (LEONE-HT)

Antibody-mediated Rejection | Heart Transplant Rejection | Transplant Failure

Spain
Assistance Publique - Hôpitaux de Paris
Janssen, LP

Completed

Desensitization in Kidney Allograft Using Daratumumab (DARDAR)

Kidney Transplant Rejection | Antibody-mediated Rejection | Allosensitization

France
Imperial College Healthcare NHS Trust

Completed

Standard Versus Prolonged-release Tacrolimus Monotherapy After Alemtuzumab Induction in Kidney Transplantation (TAESR)

Graft Rejection | End-stage Renal Failure

United Kingdom
University of Florida
Dentsply Implants Manufacturing GmbH

Withdrawn

The Healing of Soft Tissue Augmentation by Acellular Dermal Matrix and Autogenous Subepithelial Connective Tissue Graft

Gingival Recession, Generalized | Graft Reaction
Medical University of Vienna
Medical University Innsbruck

Completed

Bortezomib in Late Antibody-mediated Kidney Transplant Rejection (BORTEJECT)

Antibody-mediated Rejection | Late Rejection of Renal Transplant

Austria
Technische Universität Dresden

Completed

Enhanced Perioperative Mobilization (EPM) Trial (EPMIII)

Liver Resection | Colorectal Resection | Pancreatic Resection | Gastric Resection

Germany
Institute for Clinical and Experimental Medicine

Active, not recruiting

Immunological Safety and Effectiveness of the First Booster Dose of mRNA Vaccines Against COVID-19 in Kidney Transplant Recipients.

COVID-19 | Kidney Diseases | Vaccine Adverse Reaction | Kidney Transplant; Complications | Rejection Acute Renal | Rejection Chronic Renal

Czechia
Sanofi

Completed

Alfuzosin for Treating Acute Urinary Retention

Acute Urinary Retention

China
Cairo University

Completed

Acute Phase Reactant in Non-COVID-19 Bacterial Pneumonia

Pneumonia | Acute-Phase Reaction

Egypt
Charite University, Berlin, Germany

Active, not recruiting

Donor-derived Cell-free DNA for Early Diagnosis of Antibody-mediated Rejection (cfDNA-DSA)

Kidney Transplant Rejection | Antibody-mediated Rejection | Kidney Transplant Failure

Germany
Columbia University
Veloxis Pharmaceuticals

Active, not recruiting

Envarsus on the Effect of Total Tacrolimus Dose/Trough Level Ratio on Renal Function (eGFR) in Kidney Transplantation

Renal Transplant Rejection | Kidney Transplant Failure and Rejection

United States
Eye & ENT Hospital of Fudan University

Completed

Dexmedetomidine Combined With Hydromorphone in Tonsillectomy and Adenoidectomy

Agitated; State, Acute Reaction to Stress

China
Biologische Heilmittel Heel GmbH

Completed

Neuronal Correlates of Neurexan® Action in Mildly to Moderately Stressed Probands (NEURIM)

Acute Stress Reaction

Germany
Biologische Heilmittel Heel GmbH

Completed

Explorative Efficacy Profile of Neurexan® in an Experimental Acute Stress Setting in Healthy Subjects (NEUPRO-DB)

Acute Stress Reaction

Germany
Biologische Heilmittel Heel GmbH

Completed

Explorative Open Label Study of Efficacy Profile of Neurexan® in Experimental Acute Stress Setting in Healthy Subjects (NEUPRO-OL)

Acute Stress Reaction

Germany
Vanderbilt University Medical Center

Enrolling by invitation

Disorders of the Acute Phase Response Following Trauma and Invasive Surgery

Acute Phase Response

United States
Imperial College London
Cambridge University Hospitals NHS Foundation Trust; National Institute for... and other collaborators

Active, not recruiting

Transplant Antibody-Mediated Rejection: Guiding Effective Treatments (TAR:GET-1)

Kidney Transplant Rejection | Antibody-mediated Rejection

United Kingdom
New York Hospital Queens
New York State Department of Health

Unknown

Confusion in the Elderly After Colon Surgery

Inflammation | Delirium | Confusion | Surgery | Acute Phase Reaction

United States
University of Wisconsin, Madison
Bristol-Myers Squibb

Withdrawn

Belatacept in Kidney Transplantation of Moderately Sensitized Patients (BelatPilot)

End Stage Renal Disease | Antibody Mediated Rejection

United States

Clinical Trials on Acute Graft Rejection

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