Clinical Trials on Acute Malaria

Total 16872 results

Kwame Nkrumah University of Science and Technology
Malaria Capacity Development Consortium

Completed

Efficacy,Safety and Tolerability of Dihydroartemisinin-Piperaquine for Uncomplicated Malaria in Pregnancy in Ghana (DHAPPQ/MIP)

Pregnancy Complicated by Malaria as Antepartum Condition

Ghana
National Institute of Malariology, Parasitology...
Institute of Tropical Medicine, Belgium

Unknown

P. Falciparum Resistance to Artemisinin in Vietnam

Drug Resistant Malaria Due to Plasmodium Falciparum

Vietnam
Groupe de Recherche Action en Sante
Institut National de la Santé Et de la Recherche Médicale, France; European...

Active, not recruiting

Follow-up of Immunological Pattern and Pregnancy Outcomes in Women Previously Received Placental Malaria Vaccine (PRIMVACLongT)

Malaria in Pregnancy

Burkina Faso
Liverpool School of Tropical Medicine
Indonesia-MoH; Gadjah Mada University; Yayasan Pengembangan Kesehatan dan Masyarakat...

Completed

Intermittent Preventive Treatment With Dihydroartemisinin-piperaquine in Papua, Indonesia (STOPMiP-2)

Malaria in Pregnancy

Indonesia
National Malaria Control Programme, Madagascar
Sanofi; Population Services International; Institut Pasteur de Madagascar; Reggio... and other collaborators

Completed

ACT for the Home Management in Malagasy Children

Fever | Suspected Malaria

France
University of Kinshasa
Novartis; European and Developing Countries Clinical Trials Partnership (EDCTP)

Completed

Comparison of ISTp- PYRAMAX-US-RDT to IPTp-SP to Prevent Malaria in Pregnant Women in DRC (ULTRAPYRAPREG) (ULTRAPYRAPREG)

Malaria in Pregnancy

Congo, The Democratic Republic of the
Institute of Tropical Medicine, Belgium
KU Leuven; Institut National de Recherche Biomédicale. Kinshasa, République... and other collaborators

Completed

Clinical Decision Support in Non-typhoidal Salmonella Bloodstream Infections in Children (DeNTS)

Bloodstream Infection | Malaria,Falciparum | Severe Malaria | Salmonella Bacteremia

Belgium
Medicines for Malaria Venture
GlaxoSmithKline; ICON plc; QIMR Berghofer Medical Research Institute; Swiss BioQuant... and other collaborators

Completed

Phase 1b MMV367 PK/PD and Safety in Healthy Adult Volunteers Experimentally Infected With Blood Stage P. Falciparum

Pathologic Processes | Infections | Systemic Inflammatory Response Syndrome | Inflammation | Vector Borne Diseases | Parasitic Diseases | Protozoan Infections | Malaria | Parasitemia | Malaria,Falciparum | Anti-Infective Agents | Antimalarials

Australia
Institut Pasteur
Institut Pasteur de Bangui

Completed

Efficacy of Antifolates Against Malaria in HIV-infected Pregnant Women and the Emergence of Induced Resistance in Plasmodium Falciparum (MACOMBA)

HIV Infection | Malaria in Pregnancy

Central African Republic
Duke University

Completed

Novel mHealth Platform to Ensure Quality of Community-based Malaria Diagnosis

Quality Assurance of Malaria Diagnosis

Kenya
The Mentor Initiative
Ministry of Health, Liberia

Completed

Liberia Insecticide Treated Durable Wall Linings Study: Protocol for a Cluster Randomised Trial (DL)

Anemia | Malaria, Falciparum

Liberia
Centers for Disease Control and Prevention
Ministry of Health and Population, Malawi

Completed

Prevention of Malaria During Pregnancy Using Intermittent Preventive Treatment With Sulfadoxine-Pyrimethamine: Malawi

HIV Infections | Malaria, Falciparum

Malawi
University of Copenhagen
London School of Hygiene and Tropical Medicine; National Institute for Medical...

Completed

Interactions Between Artemether-lumefantrine and Antiretrovirals in HIV-patients With Uncomplicated Malaria in Tanzania (InterACT)

HIV Infections | Malaria, Falciparum

Tanzania
Ministry of Health and Medical Services, Solomon...
World Health Organization

Terminated

A Randomized Controlled Trial for Intermittent Preventive Treatment in Pregnancy With Fansidar in Solomon Islands (IPTpRCT)

Malaria | Malaria in Pregnancy

Solomon Islands
Swiss Tropical & Public Health Institute
London School of Hygiene and Tropical Medicine; Hospital Clinic of Barcelona; Ifakara Health Research and Development Centre and other collaborators

Unknown

The Community Effectiveness of IPTi in Southern Tanzania

Anemia | Malaria, Falciparum

Tanzania
Claude Bernard University

Unknown

Randomized Trial of Erythropoietin During Cerebral Malaria (EPOMAL)

Cerebral Malaria

Mali
Makerere University
Ministry of Health, Uganda; Sanofi-Synthelabo

Unknown

Efficacy of Intrarectal Versus Intravenous Quinine for the Treatment of Childhood Cerebral Malaria

Cerebral Malaria

Uganda
Makerere University

Unknown

Mannitol as Adjunct Therapy for Childhood Cerebral Malaria

Cerebral Malaria

Uganda
University of Oxford
Mahidol University

Not yet recruiting

A Safety, Immunogenicity and Efficacy Study of PvRII/Matrix-M in Healthy Thai Adults Living in Thailand ( MIST3 ) (MIST3)

Plasmodium Vivax Infection | Malaria Vaccine

Thailand
ORIYOMI OMOTOYOSI AKINYOTU
University of Ibadan

Completed

A Comparative Study of Mefloquine and S-P as Prophylaxis Against Malaria in Pregnant HIV + Patients

Malaria in Pregnant HIV + Patients

Nigeria
Institut de Recherche pour le Developpement
Saint Antoine University Hospital; Ministry of Health, Benin; Sidaction; National... and other collaborators

Completed

Prevention of Pregnancy-associated Malaria in HIV-infected Women: Cotrimoxazole Prophylaxis Versus Mefloquine (PACOME)

HIV Infections | Malaria in Pregnancy

Benin
University Health Network, Toronto
University of Toronto; Makerere University

Completed

Inhaled Nitric Oxide for the Adjunctive Therapy of Severe Malaria: a Randomized Controlled Trial

Severe Malaria

Uganda
Institute of Tropical Medicine, Belgium
Tropical Diseases Research Centre, Zambia

Completed

Establishing Effectiveness of Daily Co-trimoxazole Prophylaxis For Prevention of Malaria in Pregnancy

HIV Infections | Malaria in Pregnancy

Zambia
London School of Hygiene and Tropical Medicine
University of Nairobi

Completed

Study of the Impact of Intermittent Preventive Treatment in Schools on Malaria, Anaemia and Education.

Malaria, Falciparum

Kenya
International Rescue Committee
Duke University

Completed

Impact of a Parenting Program in Liberia to Improve Parenting, Education, and Health Outcomes for Children in Liberia

Parenting Behavior | Pre-academic and Developmental Skills | Malaria Prevention

Liberia
Medical Research Council Unit, The Gambia

Completed

Chloroquine and Post Malaria Anaemia Study (CQ-PMA)

Malaria Anaemia
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Recruiting

Efficacy, Safety, and PK of M5717 in Combination With Pyronaridine as Chemoprevention in Adults and Adolescents With Asymptomatic Plasmodium Falciparum Infection (CAPTURE-2)

Malaria Infection

Kenya, Burkina Faso, Gambia, Zambia
University of Rochester
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Enteral Levetiracetam For Seizure Control In Pediatric Cerebral Malaria (LVT1)

Epilepsy | Seizure | Cerebral Malaria

Malawi
Radboud University Medical Center
Clinical Research Unit of Nanoro

Unknown

Non-specific Effects of Vaccination on Mortality and Morbidity (NOVAC)

Vaccine Reaction | Anemia | Malaria,Falciparum | Salmonella Bacteraemia

Burkina Faso
Duke University
National Institute of Allergy and Infectious Diseases (NIAID)

Recruiting

Improving Neonatal Health Through Rapid Malaria Testing in Early Pregnancy With High-Sensitivity Diagnostics (INTREPiD)

Pregnancy | Preterm Birth | Gestational Age and Weight Conditions | Malaria in Pregnancy | Stillbirth | Low Birthweight | Malaria,Falciparum | Neonatal Health | Malaria in Childbirth

Congo, The Democratic Republic of the, Kenya
University of Utah
National Institute of Allergy and Infectious Diseases (NIAID); Duke University and other collaborators

Completed

Hyperphenylalaninemia in Cerebral Malaria

Plasmodium Falciparum Malaria

Tanzania
Liverpool School of Tropical Medicine
London School of Hygiene and Tropical Medicine; University of Copenhagen; University... and other collaborators

Completed

Improving PRegnancy Outcomes With Intermittent preVEntive Treatment in Africa (IMPROVE)

Pregnancy | Malaria | Malaria in Pregnancy

Kenya, Malawi, Tanzania
GlaxoSmithKline
PATH; Iqvia Pty Ltd; AMP (Agence de Médecine Préventive) (in French); RAFT (Réseau... and other collaborators

Completed

A Surveillance Study of Diseases Specified as Adverse Events of Special Interest, of Other Adverse Events Leading to Hospitalisation or Death, and of Meningitis in Children in Africa Prior to Implementation of the RTS,S/AS01E Candidate Vaccine

Malaria | Malaria Vaccines

Ghana, Burkina Faso, Kenya
University of Zimbabwe
National Institute of Health Research, Zimbabwe

Completed

Worm Infestation and Child Health in Zimbabwe (Zimworms)

Integrated Control of Malaria and Polyparasitism

Zimbabwe
London School of Hygiene and Tropical Medicine
HealthNet TPO; Health Protection and Research Organisation; Medical Emergency...

Completed

Cluster Randomised Trial of Malaria RDTs Used by CHWs in Afghanistan

Pneumonia | Fever | Malaria | Acute Febrile Illness

Afghanistan
University of Rochester
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

A Safety and Feasibility Study of Enteral LVT vs. Standard of Care for Seizure Control in Pediatric CM (LVT2)

Epilepsy | Seizure | Cerebral Malaria

Malawi
University of Oxford

Completed

Study to Compare the Triple ACT AL+AQ With the ACT AL in Cambodia and Vietnam (TACT-CV)

Malaria, Falciparum

Cambodia, Vietnam
London School of Hygiene and Tropical Medicine
DBL -Institute for Health Research and Development

Completed

Relationships Between the Use of Antimalarial Drugs in Pregnancy and Plasmodium Falciparum Resistance

Birth Weight | Malaria in Pregnancy | Anaemia

Burkina Faso
Groupe de Recherche Action en Sante
European Vaccine Initiative

Recruiting

Malaria Burden in Pregnant Women and the Incidence of Pregnancy in a Cohort of Nulligravida (EPI-PAM)

Maternal Malaria During Pregnancy - Baby Not Yet Delivered

Burkina Faso
Noguchi Memorial Institute for Medical Research
Ghana National Malaria Control Programme; Communities

Completed

Determining the Impact of Scaling up Mass Testing, Treatment and Tracking on Malaria Prevalence in Ghana (DetI-MTTT)

Malaria Asymptomatic Parasitaemia

Ghana
Noguchi Memorial Institute for Medical Research
World Health Organization

Completed

Impact of Scaling up Mass Testing, Treatment and Tracking on Malaria Prevalence Among Children

Malaria | Malaria, Asymptomatic Parasitaemia

Ghana
Foundation for Innovative New Diagnostics, Switzerland
Universidad de Antioquia

Completed

Clinical Performance of the HRP2 HS-RDT for Malaria Diagnosis in Pregnant Women (HSRDT MiP)

Diagnoses Disease | Plasmodium Falciparum | Pregnancy Malaria

Colombia
University of Bamenda
Ministry of Science and Technology of the People´s Republic of China; National...

Completed

Antimalaria Drugs Susceptibility Testing for an Effective Management of Infected Patients in Sub-Sahara Africa

Drug Resistant Malaria Due to Plasmodium Falciparum

Cameroon
Liverpool School of Tropical Medicine
University of Copenhagen; University of Toronto; Centers for Disease Control... and other collaborators

Completed

Improving PRegnancy Outcomes With PReVEntive Therapy in Africa-2 (IMPROVE-2) (IMPROVE-2)

Pregnancy; HIV; Malaria

Kenya
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Enhancing Preventive Therapy of Malaria In Children With Sickle Cell Anemia in East Africa (EPiTOMISE) (EPiTOMISE)

Malaria,Falciparum

Kenya
Centre de Recherche Médicale de Lambaréné
Institute of Tropical Medicine, University of Tuebingen

Not yet recruiting

A Crossover Bioavailability Clinical Trial of Parenteral Pyronaridine and Artesunate

Severe Malarial Treatment

Gabon
Department of Medical Research, Lower Myanmar
National Malaria Control Program, Myanmar

Completed

Drug Resistance Among Asymptomatic Infection

Asymptomatic Infections | Drug Resistant Malaria | Migrant Workers

Myanmar
Sanaria Inc.
Centre de Recherche Médicale de Lambaréné; Institute of Tropical Medicine,...

Completed

Effect of Plasmodium Falciparum Exposure and Sickle Cell Trait on Infection Rates and Kinetics After IV Administration of PfSPZ Challenge

Malaria | Plasmodium Falciparum Malaria

Gabon
Johns Hopkins Bloomberg School of Public Health
Johns Hopkins University; University of Maryland; University of California, San... and other collaborators

Recruiting

Platelet-Directed Whole Blood Transfusion Strategy for Malaria (PLATFORM)

Thrombocytopenia | Severe Malaria

United States, Zambia
Liverpool School of Tropical Medicine
London School of Hygiene and Tropical Medicine; University of Bergen; Kamuzu... and other collaborators

Completed

Acceptability and Feasibility in the Context of the IMPROVE Trial in Kenya

Malaria in Pregnancy | Adherence, Treatment

Kenya

Clinical Trials on Acute Malaria

Sponsors and Collaborators

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Drug Interventions

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CROs in Armenia

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