Clinical Trials on Acute-On-Chronic Liver Failure

Total 8804 results

Amgen

Completed

Study of the Pharmacokinetics and Safety of Carfilzomib in Patients With Multiple Myeloma and Renal Disease

End-stage Renal Disease | Relapsed Multiple Myeloma

United States, Australia, Canada
Brenda Cooper, MD

Completed

Phase I Trial of Universal Donor NK Cell Therapy in Combination With ALT803

Soft Tissue Sarcoma | Acute Myeloid Leukemia | Hodgkin Lymphoma | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Non Hodgkin Lymphoma | Chronic Myeloid Leukemia | Myelodysplastic Syndrome | Plasma Cell Myeloma | Rhabdomyosarcoma | Colon Carcinoma | Adenocarcinoma of Rectum | Myeloproliferative Syndromes and other conditions

United States
US Department of Veterans Affairs

Completed

Hepatitis C Self-Management

Hepatitis C | Chronic Disease

United States
University of Saskatchewan

Not yet recruiting

Irreversible Electroporation (NanoKnife ®) and Immunotherapy for the Treatment of Stage IV Colorectal Cancer

Liver Metastasis Colon Cancer
Memorial Sloan Kettering Cancer Center

Completed

Utility of Intra-operative Image Guidance System for Missing Metastases

Colorectal Cancer | Metastatic to the Liver
Complejo Hospitalario Universitario de Albacete
University of Warwick; University Hospitals Coventry and Warwickshire NHS Trust and other collaborators

Not yet recruiting

An Integrated Solution for Sustainable Care for Multimorbid Elderly Patients With Dementia (CAREPATH)

Behavioral Symptoms | Coronary Artery Disease | Heart Failure | Stroke | Hypertension | Diabetes | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Malnutrition | Asthma | Dementia | Alzheimer Disease | Frailty | Sarcopenia | Comorbidities and Coexisting Conditions

Spain
Biocad

Completed

An Open-label Randomized Multicenter Phase III Clinical Study Comparing Safety and Efficacy of Algeron (Cepeginterferon Alfa-2b) and and PegIntron (Peginterferon Alfa-2b) in Combination With Ribavirin as Combined Treatment of Chronic Hepatitis C in Human Immunodeficiency Virus-1 Infected Patients

Hepatitis | Hepatitis C | Hepatitis C/ Human Immunodeficiency Virus Coinfection

Russian Federation
Jinling Hospital, China

Unknown

Ulcerative Colitis Endoscopic Index of Severity and Fecal Calprotectin to Predict the Reaction to Corticosteroids of Acute Severe Ulcerative Colitis

Acute Severe Colitis (ASC)

China
University of California, San Diego
RF Surgical Systems, Inc.

Completed

RF Surgical Sponge-Detecting System on the Function of Pacemakers and Implantable Cardioverter Defibrillators (RF)

Heart Failure | Cardiac Arrhythmia | Cardiomyopathy | Chronic Thromboembolic Pulmonary Hypertension

United States
VA Office of Research and Development

Recruiting

Remote Ischemic Preconditioning for Renal and Cardiac Protection in Congestive Heart Failure (RICH) Trial (RICH)

Heart Failure | Acute Kidney Injury | Percutaneous Coronary Intervention | Contrast Induced Nephropathy | Coronary Angiography

United States
University of Minnesota
Fairview Health Services

Completed

Mindfulness & Stress Management Study for Cardiac Patients

Myocardial Infarction | Heart Diseases | Heart Failure | Coronary Artery Bypass | Chronic Stable Angina | Angioplasty

United States
Solve ME/CFS Initiative

Recruiting

Solve Together: A Data Collection Platform for the Collection of Patient and Control Health Information to Support Future Research That Will Accelerate Understanding of the Causes of and Possible Treatments for ME/CFS and Other Chronic Diseases, Including Post-viral Illnesses

ME/CFS | Post-Acute COVID-19 Syndrome

United States
Odense University Hospital
Sygehus Lillebaelt; Svendborg Hospital; Hospital of South West Jutland

Completed

The Value of Laparoscopic Ultrasound in Patients Undergoing Laparoscopic Resection for Cancer of the Colon or Rectum

Colon Cancer | Liver Metastases | Rectum Cancer

Denmark
University of Valladolid

Recruiting

Characterization of Long Covid Pain in Primary Care

Musculoskeletal Pain | Chronic Pain | Long COVID

Spain
Pfizer
Medivation, Inc.

Completed

Study of BMN 673, a PARP Inhibitor, in Patients With Advanced Hematological Malignancies

Acute Myeloid Leukemia | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Myelodysplastic Syndrome

United Kingdom, United States
Novartis Pharmaceuticals

Withdrawn

Canakinumab in the Treatment of Gouty Arthritis Flare(s) and Prevention of New Flares in Patients With Chronic Kidney Disease

Acute Gouty Arthritis
Stanford University
Novartis

Completed

Phase 1 Nilotinib in Steroid Dependent/Refractory Chronic Graft Versus Host Disease

Lymphoma, Non-Hodgkin | Lymphoma, T-Cell, Peripheral | Bone Marrow Transplant Failure

United States, Canada
Gao Tao

Completed

Indicators Predicting Surgery in Acute Severe Ulcerative Colitis(ASUC)

Surgery | Ulcerative Colitis Acute
University College, London

Completed

Body Mass Index and Initial Presentations of Cardiovascular Diseases (CALIBER)

Heart Failure | Stroke | Peripheral Arterial Disease | Acute Myocardial Infarction | Abdominal Aortic Aneurysm | Angina

United Kingdom
University of Southern California
National Cancer Institute (NCI)

Completed

High Definition Single Cell Analysis in Colorectal Cancer

Stage IV Colorectal Cancer | Metastatic Carcinoma in the Liver

United States
Sun Yat-sen University

Terminated

FUDR/Oxaliplatin HAI Plus Irinotecan vs. FOLFOXIRI Chemotherapy in Treating Initially Unresectable CRCLM

Metastatic Colorectal Cancer | Liver Metastases

China
University Hospital, Clermont-Ferrand
Ministry of Health, France; French Society of Hematology

Recruiting

Faecal Microbiota Transplantation After Allogeneic Stem Cell Transplantation (TMF-Allo)

Lymphoma, Non-Hodgkin | Myelodysplastic Syndromes | Hodgkin Lymphoma | Chronic Lymphocytic Leukemia | Myeloma | Acute Leukemia in Remission | Myeloproliferative Syndrome

France
University of South Florida

Withdrawn

Using Continuous Positive Airway Pressure to Reduce the Incidence of Acute Kidney Injury in Hospitalized Patients With Chronic Kidney Disease

Obstructive Sleep Apnea | Chronic Kidney Disease

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Arsenic Trioxide and Imatinib Mesylate in Treating Patients With Accelerated Phase or Blastic Phase Chronic Myelogenous Leukemia or Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Leukemia

United States
Nanfang Hospital of Southern Medical University

Recruiting

Induced-T Cell Like NK Cells for B Cell Malignancies

B Cell Lymphoma | B-cell Acute Lymphoblastic Leukemia | B Cell Leukemia | B-cell Lymphoma Refractory | B-cell Lymphoma Recurrent

China
Dana-Farber Cancer Institute
Brigham and Women's Hospital

Completed

GM-CSF Vaccinations After Allogeneic Blood Stem Cell Transplantation in Patients With Advanced Myeloid Malignancies

Refractory Acute Myeloid Leukemia | Myelodysplastic Syndrome RAEB-I or RAEB-II | Refractory CML Myeloid Blast Crisis

United States
Assistance Publique - Hôpitaux de Paris
Action, France

Unknown

Impact of COVID19 Outbreak in Cardiac Acute Care (CCU-COVID19)

Heart Failure | Acute Coronary Syndrome | COVID

France
Tri-Service General Hospital

Active, not recruiting

Study on Post-Acute COVID-19 Syndrome in Improvement of COVID-19 Rehabilitated Patients by Respiratory Training

COVID-19, Post-Acute COVID-19 Syndrome, Dyspnea, Incentive Spirometer

Taiwan
University of Lorraine

Completed

Laparoscopic Cholecystectomy Using Airseal in Children (VBAS)

Cholecystitis, Acute | Child, Only | Cholecystitis, Chronic | Gall Stones (& [Calculus - Gall Bladder]) | Pancreatitis Due to Gallstones

France
Charite University, Berlin, Germany

Completed

Longitudinal Cohort Study - for the Treatment of Acute Postoperative Pain and Postoperative Delirium, Postoperative Cognitive Dysfunctions, and Chronic Pain.

Pain | Delirium | Postoperative Cognitive Dysfunction

Germany
Genzyme, a Sanofi Company
European Society for Blood and Marrow Transplantation

Completed

Analysis of Data Collected in the European Group for Blood and Marrow Transplantation (EBMT) Registry for Off-Label Transplant Use of Plerixafor

Lymphoma | Acute Leukemia | Myelodysplastic Syndrome | Solid Tumors | Myeloproliferative Neoplasm | Chronic Leukemia | Plasma Cell Disorders
Massachusetts General Hospital

Recruiting

Open Lung Strategy, Gas Distribution and Right Heart Function in ARDS Patients

Respiratory Distress Syndrome | Mechanical Ventilation Complication | Right Ventricular Dysfunction | ARDS, Human | Right Heart Failure | Lung Injury, Acute | Alveolar Edema

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); The Wayne D. Kuni and Joan E. Kuni Foundation

Completed

Fludarabine Phosphate, Cyclophosphamide, Total-Body Irradiation, and Donor Bone Marrow Transplant Followed by Donor Natural Killer Cell Therapy, Mycophenolate Mofetil, and Tacrolimus in Treating Patients With Hematologic Cancer

Diffuse Large B-Cell Lymphoma | Acute Myeloid Leukemia | Refractory Hodgkin Lymphoma | Previously Treated Myelodysplastic Syndrome | Recurrent Mantle Cell Lymphoma | Waldenstrom Macroglobulinemia | Acute Lymphoblastic Leukemia | Refractory Plasma Cell Myeloma | Recurrent Small Lymphocytic Lymphoma | Refractory... and other conditions

United States
University Health Network, Toronto
Oslo University Hospital

Completed

Study of Decidual Stromal Cells to Treat COVID-19 Respiratory Failure

COVID-19 | Acute Respiratory Distress Syndrome

Canada
Cynata Therapeutics Limited
Cerebral Palsy Alliance

Completed

The MEseNchymal coviD-19 Trial: MSCs in Adults With Respiratory Failure Due to COVID-19 or Another Underlying Cause (MEND)

Covid19 | Acute Respiratory Distress Syndrome

Australia
University of Zurich

Unknown

Effects of OXY111A in Primary and Secondary Hepato-Pancreato-Biliary Neoplasm (OXY1A)

Colorectal Neoplasms | Pancreatic Neoplasms | Cholangiocarcinoma | Hepatocellular Cancer

Switzerland
Russian Federation of Anesthesiologists and Reanimatologists
Kuban State Medical University

Recruiting

The Role of Concomitant Diseases in Postoperative Complications Risk Stratification. (STOPRISK)

Stroke | Epilepsy | Diabetes | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Neuromuscular Diseases | Parkinson's Disease | Anemia | Coronary Heart Disease | Chronic Heart Failure | Alzheimer's Disease | Bronchial Asthma | Heart Rhythm Disorders

Russian Federation
New York Medical College

Unknown

Trial of Cladribine, Cytarabine, Mitoxantrone, Filgrastim (CLAG-M) in Relapsed Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia | Lymphoblastic Lymphoma | Chronic Myelogenous Leukemia | Burkitts Leukemia/Lymphoma

United States
Novartis Pharmaceuticals

Recruiting

Phase I/II Study of Rapcabtagene Autoleucel in CLL, 3L+ DLBCL, ALL and 1L HR LBCL

Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Diffuse Large B-cell Lymphoma | Small Lymphocytic Lymphoma | Large B-cell Lymphoma

Japan, Australia, Germany, Italy, Spain, France, Austria, United States
VA Office of Research and Development
John D. Dingell VA Medical Center

Recruiting

Predictors of Post-COVID Clinical and Cognitive Consequences (SCLC)

Obstructive Sleep Apnea | Post Acute Sequelae of SARS CoV 2 Infection

United States
Chinese University of Hong Kong

Terminated

Prevalence and Clinical Course of Chronic Hep B Infection in IBD and Rheumatologic Disease

Rheumatic Diseases | Hepatitis B, Chronic | Crohn Disease | Ulcerative Colitis | Inflammatory Bowel Disease

Hong Kong
Services Institute of Medical Sciences, Pakistan
Getz Pharma

Completed

The Role Of Nitazoxanide, Interferon Alfa And Ribavirin In Treatment Of Hepatitis C Infected Type 2 Diabetic Patients (HEP-C-FM)

Hepatitis C, Chronic | DIABETES MELLITUS Type 2

Pakistan
University of Pennsylvania
National Institutes of Health (NIH); Medical College of Wisconsin

Enrolling by invitation

Evaluating a Comprehensive Multimodal Outpatient Rehabilitation Program for PASC Program to Improve Functioning of Persons Suffering From Post-COVID-19 Syndrome: A Randomized Controlled Trial

Cognitive Impairment | Dyspnea | Long COVID | Long Covid19 | Post-Acute COVID-19 | Post-Acute COVID-19 Infection | Post-Acute COVID-19 Syndrome | Orthostasis

United States
University of Aarhus

Recruiting

Comparison of Gastrointestinal Motility in Healthy Children and Children With Constipation

Constipation | Childhood Acute Lymphoblastic Leukemia | Neurofibromatosis 1 | Chronic Constipation With Overflow

Denmark
University of Freiburg

Active, not recruiting

Analysis of Intestinal Defensin Expression in Acute GVHD

Ulcerative Colitis | GVHD,Acute | Morbus Crohn

Germany
University of Maryland, Baltimore

Completed

HCV Treatment Immune Response With Grazoprevir/Elbasvir Before or After Renal Transplant

Renal Insufficiency, Chronic | Hepatitis C | Disorder of Transplanted Kidney

United States
Ottawa Hospital Research Institute
Gilead Sciences; CIHR Canadian HIV Trials Network

Completed

HIV Drug Switch Followed by HCV Therapy in HIV-HCV Co-Infection (CTN289)

Hepatitis C, Chronic | Human Immunodeficiency Virus

Canada
George Washington University

Completed

The Effect of HIV Tat Protein on HCV Replication in an In-vitro Model System

Hepatitis C, Chronic | Human Immunodeficiency Virus (HIV)

United States
Nkarta Inc.

Recruiting

NKX019, Intravenous Allogeneic Chimeric Antigen Receptor Natural Killer Cells (CAR NK), in Adults With B-cell Cancers

Lymphoma, Non-Hodgkin | Waldenstrom Macroglobulinemia | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | B-cell Acute Lymphoblastic Leukemia | Small Lymphocytic Lymphoma | Large B-cell Lymphoma | Indolent Lymphoma | Aggressive Lymphoma | Large-cell Lymphoma

United States, Australia
National Cancer Institute (NCI)

Terminated

Cetuximab and/or Dasatinib in Patients With Colorectal Cancer and Liver Metastases That Can Be Removed by Surgery

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Liver Metastases | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer

United States

Clinical Trials on Acute-On-Chronic Liver Failure

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