Clinical Trials on Adenoviral Keratoconjunctivitis

Total 982 results

New York Medical College
Johns Hopkins University; University of Colorado, Denver; Children's Hospital... and other collaborators

Recruiting

Adenovirus-specific Cytotoxic T-lymphocytes for Refractory Adenovirus Infection

Primary Immune Deficiency Disorder | Adenovirus

United States
Fujian Cancer Hospital

Enrolling by invitation

An Exploratory Single-arm Study: PD-1 With Recombinant Human Adenovirus Type 5 Injection for Malignant Melanomas

Malignant Melanomas

China
Institut Català d'Oncologia

Completed

Phase I Endovenous Administration of Oncolytic Adenovirus ICOVIR-5 in Patients With Advanced or Metastatic Melanoma

Locally Advanced or Metastatic Melanoma

Spain
Sun Yat-sen University

Unknown

TACE Plus Recombinant Human Adenovirus for Hepatocellular Carcinoma

Hepatocellular Carcinoma

China
Federal University of São Paulo
Allergan

Completed

Safety Study of the Use of Topical Cyclosporine in the Treatment of Dry Eye Disease

Evaporative Dry Eye Disease | Primary Sjogren Syndrome | Secondary Sjogren Syndrome | Aqueous Deficient Dry Eye Disease

Brazil
Bedford Hospital NHS Trust
Moorfields Eye Hospital NHS Foundation Trust; University Hospitals Bristol... and other collaborators

Unknown

Treating Dry Eyes and Corneal Ulcers With Fingerprick Autologous Blood (FAB)

Dry Eyes | Sjogren's Disease With Dry Eyes | Persistent Corneal Epithelial Defects | Chronic Corneal Ulcers

United Kingdom
The First Affiliated Hospital with Nanjing Medical...
Academy Military Medical Science, China

Unknown

Safety Study of Adenovirus Hepatocyte Growth Factor to Treat Ischemic Heart Disease

Ischemic Heart Disease

China
Fundación Huésped
CanSino Biologics Inc.; Canadian Center for Vaccinology; Hospital Fernandez

Recruiting

Phase IIb Trial of Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector) (Ad5-nCoV) in Adults 18 Years of Age and Older. (COVID-19)

Covid19

Argentina
Taipei Veterans General Hospital, Taiwan

Withdrawn

Objective Measurement Methods for Autoimmune Disease and Dry Eye Syndrome

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Systemic Sclerosis | Dry Eye Syndrome | Sjögren's Syndrome | Ankylosing Spondylitis

Taiwan
Boston Sight
EYEdeal scanning, LTC

Completed

Pilot Study to Investigate the Feasibility, Reliability and Efficacy of Utilizing OCT to Automate PROSE Fitting

Dry Eye Syndromes | Keratoconjunctivitis Sicca | Keratoconus | Sjogren's Syndrome | Ocular Surface Disease | Ectasia | Pellucid Marginal Corneal Degeneration | Corneal Trauma | Corneal Scar

United States
Michael Pulsipher, MD

Active, not recruiting

Antiviral Cellular Therapy for Enhancing T-cell Reconstitution Before or After Hematopoietic Stem Cell Transplantation (ACES)

Cytomegalovirus Infections | EBV Infection | Adenovirus Infection

United States
Seoul National University Bundang Hospital
NewGenPharm Incoporation

Recruiting

An Exploratory Trial to Evaluate Efficacy and Safety for Combination Treatment of Adenovirus Double Suicide Gene Therapy

Pancreas Cancer

Korea, Republic of
AlloVir

Terminated

Study of Posoleucel (ALVR105,Viralym-M) for Multi-Virus Prevention in Patients Post-Allogeneic Hematopoietic Cell Transplant (Prevent)

BK Virus Infection | Epstein-Barr Virus Infections | Cytomegalovirus Infections | Adenovirus Infection | JC Virus Infection | Human Herpes Virus-6 Infection

Korea, Republic of, United States, Spain, France, Turkey, Australia, United Kingdom, Italy, Canada, Belgium
University College, London
Public Health England

Completed

Specific Respiratory Infections as Triggers of Acute Medical Events

Cardiovascular Diseases | Influenza, Human | Respiratory Syncytial Virus Infections | Adenovirus | Rhinovirus | Parainfluenza | Human Metapneumovirus Pneumonia

United Kingdom
AlloVir

Completed

Posoleucel (ALVR105, Formerly Viralym-M) for Multi-Virus Prevention in Patients Post-Allogeneic Hematopoietic Cell Transplant (Prevent)

BK Virus Infection | Epstein-Barr Virus Infections | Cytomegalovirus Infections | Adenovirus Infection | JC Virus Infection | Human Herpes Virus-6 Infection

United States
Centers for Disease Control and Prevention, China
Beijing Ditan Hospital; National Institutes for Food and Drug Control, China

Unknown

Clinical Trial of Recombinant Adenovirus Type 5 AIDS Vaccine

Acquired Immunodeficiency Syndrome

China
Fujian Cancer Hospital
Jiangsu Hengrui Pharmaceutical Co., Ltd.; SunWay Biotech Co., LTD.

Not yet recruiting

Recombinant Human Adenovirus Type 5 Injection Combined With PD-1 Monoclonal Antibody and Nab-paclitaxel in the Treatment of Patients With Liver Metastases From Malignant Melanoma

Liver Metastases | Malignant Melanoma
Benjamin Movsas, M.D.

Withdrawn

Oncolytic Adenovirus-Mediated Gene Therapy for Lung Cancer (NSCLC)

Non-small Cell Lung Cancer Stage I

United States
QIAGEN Gaithersburg, Inc

Completed

Collection and Testing of Respiratory Samples

Respiratory Syncytial Virus Infections | Influenza A | Rhinovirus | Influenza B | QIAGEN ResPlex II Advanced Panel | Infection Due to Human Parainfluenza Virus 1 | Parainfluenza Type 2 | Parainfluenza Type 3 | Parainfluenza Type 4 | Human Metapneumovirus A/B | Coxsackie Virus/Echovirus | Adenovirus Types B/C/E | Coronavirus Subtypes 229E and other conditions

United States
Tianjin Medical University Second Hospital

Recruiting

Oncolytic Adenovirus(H101) Combined With PD-1 Inhibitors in Patients With Advanced Malignant Pleural Mesothelioma

Malignant Pleural Mesothelioma, Advanced

China
Shanghai Fengxian District Central Hospital
Shanghai Yuansong Biotechnology Co., LTD

Recruiting

Safety and Efficacy of Recombinant Oncolytic Adenovirus L-IFN Injection in Relapsed/Refractory Solid Tumors Clinical Study (YSCH-01)

Melanoma | Breast Cancer | Head and Neck Cancer | Lung Cancer | Bladder Cancer | Cervical Carcinoma | Ovarian Carcinoma

China
Shenzhen Geno-Immune Medical Institute

Unknown

Antigen-specific Cytotoxic T Cells in the Treatment of Opportunistic Infections

Tuberculosis | CMV Infection | EBV Infection | Adenovirus Infection | Fungus Infection | Pathogen Infection | BKV Infection

China
CG Oncology, Inc.

Terminated

Efficacy Study of Recombinant Adenovirus for Non Muscle Invasive Bladder Cancer (BOND)

Carcinoma in Situ | Transitional Cell Carcinoma | Bladder Cancer | Carcinoma in Situ Concurrent With Papillary Tumors

United States
Erasmus Medical Center
Amsterdam UMC, location VUmc

Completed

Safety Study of Replication-competent Adenovirus (Delta-24-rgd) in Patients With Recurrent Glioblastoma

Brain Tumor | Recurring Glioblastoma

Netherlands
Lawson Health Research Institute

Completed

Ocular Manifestations in Rheumatic Diseases

Uveitis | Macular Edema | Retinal Vein Occlusion | Retinitis | Orbital Diseases | Optic Neuritis | Keratoconjunctivitis Sicca | Conjunctivitis | Blindness | Xerophthalmia | Papilledema | Iridocyclitis | Retinal Artery Occlusion | Amaurosis Fugax | Scleritis | Eye Hemorrhage | Chorioretinitis | Choroid Hemorrhage
Alcon Research

Completed

AONDA Therapeutic Indication Study I

Keratoconjunctivitis | Corneal Edema | Corneal Ulcer | Bullous Keratopathy | Bell Palsy | Corneal Dystrophy | Entropion | Filamentary Keratitis | Corneal Erosion | Foreign Body in Cornea | Sicca Syndrome; Keratoconjunctivitis (Etiology)

United States
DNAtrix, Inc.
Merck Sharp & Dohme LLC

Completed

Combination Adenovirus + Pembrolizumab to Trigger Immune Virus Effects (CAPTIVE)

Nervous System Diseases | Glioma | Glioblastoma | Neuroectodermal Tumors | Brain Cancer | Gliosarcoma | Brain Neoplasm | Malignant Brain Tumor | Neoplasm, Neuroepithelial | Neoplasm by Histologic Type | Neoplasm, Nerve Tissue

United States, Canada
Murdoch Childrens Research Institute
Royal Children's Hospital; Monash Health

Recruiting

Intranasal Steroid as Medical Therapy For Sleep-Disordered Breathing in Children (MIST+)

Snoring | Tonsillar Hypertrophy | Sleep Disorder; Breathing-Related | Obstructive Sleep Apnea of Child | Sleep Disorders in Children | Adenoidal Disorder

Australia
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Study Assessing the Feasibility, Safety and Efficacy of Genetically Engineered Glucocorticoid Receptor Knock Out Virus Specific CTL Lines for Viral Infections in Immunosuppressed Cancer Patients

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | BK Virus Infection | Symptomatic COVID-19 Infection Laboratory-Confirmed | Adenovirus Infection | Cytomegaloviral Infection | JC Virus Infection

United States
DiaSorin Molecular LLC

Not yet recruiting

LIAISON NES Influenza (FLU) A/B, Respiratory Syncytial Virus (RSV), & Coronavirus Disease 2019 (COVID-19) in Symptomatic Patients in Australia

Coronavirus Disease 2019 | Influenza A | Respiratory Syncytial Virus (RSV) | Adenovirus | Influenza Type B | Enterovirus | Mycoplasma Pneumonia | Bordetella Parapertussis Infection | Chlamydia Pneumonia | Para Influenza | Bordetella Pertussis Infection, Respiratory

Australia
TILT Biotherapeutics Ltd.
Merck Sharp & Dohme LLC

Recruiting

Oncolytic Adenovirus Coding for TNFa and IL2 (TILT-123) With Pembrolizumab or Pembrolizumab and Pegylated Liposomal Doxorubicin as Treatment for Ovarian Cancer. (PROTA)

Platinum-resistant Ovarian Cancer | Platinum-Resistant Fallopian Tube Carcinoma | Platinum-Resistant Primary Peritoneal Carcinoma | Platinum-Refractory Fallopian Tube Carcinoma | Platinum-Refractory Primary Peritoneal Carcinoma | Platinum-refractory Ovarian Carcinoma | Platinum-Sensitive Ovarian... and other conditions

United States, Finland
Daniel Benjamin
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care (PTN_POPS)

Heart Failure | Epilepsy | Pain | Pneumonia | Sepsis | Inflammation | Hypertension | Chronic Kidney Diseases | Hemophilia | Schizophrenia | Central Nervous System Infections | Nosocomial Pneumonia | Insomnia | Anxiety | Bipolar Disorder | Neutropenia | Staphylococcal Infections | Bradycardia | Seizures | Urinary Tract Infections | Pulmonary... and other conditions

United States, Canada, United Kingdom, Israel, Singapore

Clinical Trials on Adenoviral Keratoconjunctivitis

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