Clinical Trials on Adults

Total 4018 results

University of California, San Diego

Not yet recruiting

Obstructive Sleep Apnea Treatment in Serious Mental Illness

Schizophrenia | Schizoaffective Disorder | Bipolar Disorder | Obstructive Sleep Apnea of Adult

United States
Hospices Civils de Lyon

Recruiting

NIRAPK : Study of the Relationship(s) Between Clinical, Biological and Pharmacokinetic Metrics and Toxicities When Niraparib is Used as Maintenance Treatment for Ovarian Cancer Patients. (NIRAPK)

Adult Patients With Platinum-sensitive, Relapsed, High Grade Serous Epithelial Ovarian Cancer

France
Beijing Anzhen Hospital

Recruiting

Vascular Responses After Percutaneous Coronary Intervention With Stenting In Patients With Obstructive Sleep Apnea (VISION)

Coronary Artery Disease | Obstructive Sleep Apnea of Adult

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

An Investigational Scan (Magnetic Resonance Elastography) in Detecting Treatment Response in Patients With Advanced Liver Cancer

Advanced Adult Hepatocellular Carcinoma | Stage III Hepatocellular Carcinoma AJCC v8 | Stage IIIA Hepatocellular Carcinoma AJCC v8 | Stage IV Hepatocellular Carcinoma AJCC v8 | Stage IVA Hepatocellular Carcinoma AJCC v8 | Stage IVB Hepatocellular Carcinoma AJCC v8 | Stage IIIB Hepatocellular Carcinoma...

United States
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Recruiting

CD19.CAR Allogeneic NKT for Patients With Relapsed or Refractory B-Cell Malignancies (ANCHOR)

Refractory B-Cell Non-Hodgkin Lymphoma | Relapsed Non Hodgkin Lymphoma | Relapsed Adult ALL | Relapsed CLL | Refractory B-Cell Small Lymphocytic Lymphoma

United States
National Cancer Institute (NCI)

Recruiting

Biospecimen Procurement for Center for Immuno-Oncology Immunotherapy Protocols

Lymphoma, Non-Hodgkin | Multiple Myeloma | Hodgkin Disease | Non-Small Cell Lung Cancer | Leukemia-Lymphoma, Adult T-Cell

United States
Cancer Research UK
AstraZeneca

Completed

A Phase I Trial of AZD3965 in Patients With Advanced Cancer

Adult Solid Tumor | Burkitt Lymphoma | Diffuse Large B Cell Lymphoma

United Kingdom
Bekasi City Public Hospital
University of Groningen

Completed

Usability Study of IeHS in Indonesia

Tuberculosis | Mobile Phone Use | Human Immunodeficiency Virus | Adult | Interpersonal Relations

Indonesia
National Cancer Institute (NCI)

Completed

Veliparib in Combination With Carboplatin and Paclitaxel in Treating Patients With Locally Advanced or Metastatic Solid Tumors

Stage IV Breast Cancer | Recurrent Breast Carcinoma | Stage IIIB Breast Cancer | Stage IIIC Breast Cancer | Estrogen Receptor Negative | Estrogen Receptor Positive | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative Breast Carcinoma | Male Breast Carcinoma | Adult Solid Neoplasm

United States
National Cancer Institute (NCI)

Completed

Suberoylanilide Hydroxamic Acid, Fluorouracil, Leucovorin, and Oxaliplatin in Treating Patients With Progressive Metastatic or Unresectable Colorectal Cancer or Other Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific | Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer | Stage III Colon Cancer | Stage III Rectal Cancer

United States
European Organisation for Research and Treatment...

Completed

NGR-TNF in Treating Patients With Advanced Solid Tumors

Kidney Cancer | Head and Neck Cancer | Colorectal Cancer | Unspecified Adult Solid Tumor, Protocol Specific

Germany, Netherlands
Yale University
Rheumatology Research Foundation

Recruiting

Rheumatology Patient Registry and Biorepository

Rheumatic Diseases | Rheumatoid Arthritis | Systemic Lupus Erythematosus | Systemic Sclerosis | Dermatomyositis | Polymyositis | Giant Cell Arteritis | Polymyalgia Rheumatica | Psoriatic Arthritis | Sjogren's Syndrome | Antiphospholipid Syndrome | Sarcoidosis | Lyme Disease | Ankylosing Spondylitis | Scleroderma | Reactive... and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Terminated

Iodine I 131 Monoclonal Antibody BC8, Fludarabine Phosphate, Cyclophosphamide, Total-Body Irradiation and Donor Bone Marrow Transplant in Treating Patients With Advanced Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or High-Risk Myelodysplastic Syndrome

Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Chronic Myelomonocytic Leukemia | Previously Treated Myelodysplastic Syndrome | Adult Acute Myeloid Leukemia in Remission | Adult Acute Lymphoblastic Leukemia in Remission | Refractory Anemia With Excess Blasts | Refractory... and other conditions

United States
University Hospital Southampton NHS Foundation...
University of Southampton

Active, not recruiting

HORIZONS: Understanding the Impact of Cancer Diagnosis and Treatment on Everyday Life

Cervical Cancer | Fallopian Tube Neoplasms | Ovarian Cancer | Fallopian Tube Cancer | Breast Neoplasm | Endometrial Neoplasms | Vulvar Cancer | Vulvar Neoplasms | Endometrial Cancer | Diffuse Large B Cell Lymphoma | Ovarian Neoplasm | Breast Cancer Female | Primary Peritoneal Carcinoma | NonHodgkin Lymphoma | Cervical... and other conditions

United Kingdom
National Cancer Institute (NCI)

Completed

Monoclonal Antibody Therapy in Treating Patients With Chronic Lymphocytic Leukemia, Lymphocytic Lymphoma, Acute Lymphoblastic Leukemia, or Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Marginal Zone Lymphoma | Splenic Marginal Zone Lymphoma | Recurrent Adult Acute Lymphoblastic Leukemia | Recurrent Small Lymphocytic... and other conditions

United States
Acerand Therapeutics (Shanghai) Limited

Recruiting

Study of ACE-86225106 to Treat Patients With Advanced Solid Tumors

Breast Cancer | Ovarian Cancer | Prostate Cancer | BRCA1 Mutation | BRCA2 Mutation | Solid Tumor, Adult

China
Gruppo Italiano Malattie EMatologiche dell'Adulto

Recruiting

Retrospective Observational Study on Infective Complications and Outcome of Patients With ALL Treated With INO (INO-FIRST)

Infections | Bacterial Infections | Fungal Infection | Acute Lymphoblastic Leukemia | Acute Lymphoblastic Leukemia, in Relapse | Viral Infection | Acute Lymphoblastic Leukemia, Adult

Italy
Oliver Cornely, MD
German Federal Ministry of Education and Research; ZKS Köln

Recruiting

Immunogenicity of COVID-19 Vaccination in Autologous HSCT or CAR-T Cells Recipients (A-COV-V)

COVID-19 | Non Hodgkin Lymphoma | Hodgkin Lymphoma, Adult

Germany
Ana Broseta Lleó
Hospital General Universitario de Valencia

Recruiting

LUS to Assess Lung Injury After Lung Resection (THORUS)

Postoperative Complications | Lung Cancer | Lung Injury | Lung Injury, Ventilator Induced | Lung Neoplasm | Thoracic | Adult ALL | Lung Inflammation | Lung Ischemia/Hypoxia | Postoperative Respiratory Complication

Spain
National Cancer Institute (NCI)

Recruiting

Tissue Collection for Studies of Lymph Cancer

Lymphoma, Non-Hodgkin | Multiple Myeloma | Hodgkin Disease | Leukemia-Lymphoma, Adult T-Cell | Lymphomatoid Granulomatosis

United States, Jamaica
National Cancer Institute (NCI)

Active, not recruiting

GDC-0449 and Erlotinib Hydrochloride With or Without Gemcitabine Hydrochloride in Treating Patients With Metastatic Pancreatic Cancer or Solid Tumors That Cannot Be Removed by Surgery

Pancreatic Ductal Adenocarcinoma | Recurrent Pancreatic Carcinoma | Stage IV Pancreatic Cancer AJCC v6 and v7 | Pancreatic Acinar Cell Carcinoma | Adult Solid Neoplasm

United States
King Chulalongkorn Memorial Hospital

Completed

Treatment Outcome Between Mycobacterium Abscessus Infection in Chronic Lung Disease and Acquired Interferon-gamma Autoantibody Syndrome

Mycobacterium Abscessus Infection | Nontuberculous Mycobacterial Pulmonary Infection | Adult-Onset Immunodeficiency With Acquired Anti-Interferon-Gamma Autoantibodies

Thailand
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Withdrawn

Buparlisib, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Advanced Solid Tumors

Stage IIIA Non-Small Cell Lung Cancer | Stage IIIB Non-Small Cell Lung Cancer | Recurrent Non-Small Cell Lung Carcinoma | Stage IV Non-Small Cell Lung Cancer | Adult Solid Neoplasm

United States
Università degli Studi di Ferrara

Completed

PEEP-induced Changed in RRI as Physiological Background of Ventilator-induced Kidney Injury (PRE-VIKI)

Acute Kidney Injury | Respiratory Distress Syndrome, Adult | Respiration, Artificial

Italy
Beijing Anzhen Hospital

Completed

OSA-ACS Project: Association of OSA and CPAP Therapy With Outcomes in ACS Patients

Acute Coronary Syndrome | Obstructive Sleep Apnea of Adult

China
University of Roma La Sapienza

Terminated

Pancreatic Cancer Can be Detected by Adrenomedullin in New Onset Diabetes Patients (PaCANOD)

Diabetes Complications | Diabetes Mellitus, Adult-Onset | Carcinoma, Pancreatic Ductal | Pancreatic Neoplasm

Italy
National Cancer Institute (NCI)

Completed

Flavopiridol in Treating Patients With Refractory Cancer

Lymphoma | Small Intestine Cancer | Prostate Cancer | Unspecified Adult Solid Tumor, Protocol Specific

United States
University Hospital, Angers

Terminated

Hyperoxia and Hypertonic Saline in Septic Shock (Hyper2S)

Septic Shock | Adult Respiratory Distress Syndrome

France
National Cancer Institute (NCI)

Completed

Selumetinib and Cetuximab in Treating Patients With Refractory Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific | Recurrent Colon Cancer | Recurrent Rectal Cancer | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer | Stage IVB Rectal Cancer

United States
Memorial Sloan Kettering Cancer Center

Recruiting

A Study of 19-28z/IL-18 in People With Acute Lymphoblastic Leukemia (ALL)

Refractory Acute Lymphoblastic Leukemia | Philadelphia-Negative ALL | Philadelphia-Positive ALL | Refractory Acute Lymphoblastic Leukemia (ALL) | Relapsed ALL, Adult | Refractory Acute Lymphoid Leukemia in Relapse

United States
Ohio State University Comprehensive Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

The RIOT Trial: Re-Defining Frailty and Improving Outcomes With Prehabilitation for Pancreatic, Liver, or Gastric Cancer (RIOT)

Malignant Solid Neoplasm | Gastric Carcinoma | Pancreatic Carcinoma | Adult Liver Carcinoma

United States
Stony Brook University
FDA Office of Orphan Products Development; State University of New York

Completed

Phase I Study of Vasoactive Intestinal Peptide in Patients With Acute Respiratory Distress Syndrome and Sepsis

Sepsis | Respiratory Distress Syndrome | Respiratory Distress Syndrome, Adult

United States
I.M. Sechenov First Moscow State Medical University

Completed

Periodontal Disease in Patients With Obstructive Sleep Apnea

Periodontal Diseases | Obstructive Sleep Apnea of Adult | Periodontal Pocket | Periodontal Attachment Loss

Russian Federation
Bicetre Hospital

Unknown

Effects of Extravascular Lung Water on Prone Position Efficacy in Patients With ARDS

Acute Respiratory Distress Syndrome | Acute Respiratory Distress Syndrome in Adult or Child
University of Oxford

Unknown

Measuring Heart and Lung Function in Critical Care

Critical Illness | Respiratory Distress Syndrome, Adult | Mechanical Ventilation Complication | Haemodynamic Instability | Gas Exchange Impairment

United Kingdom
Karolinska University Hospital

Completed

Pulmonary Pathophysiology and Inflammatory Response in Patients Treated With Ecmo for Severe Respiratory Failure

Respiratory Distress Syndrome, Adult | Respiratory Distress Syndrome, Child

Sweden
FDA Office of Orphan Products Development

Completed

Etanercept for Non-Infectious Lung Injury Following Bone Marrow Transplantation

Pneumonia | Bronchiolitis Obliterans | Respiratory Distress Syndrome, Adult

United States
University of Washington
National Heart, Lung, and Blood Institute (NHLBI); American Thoracic Society; American Society for Parenteral and Enteral Nutrition and other collaborators

Completed

A Phase II Randomized Trial of Fish Oil in Patients With Acute Lung Injury (ALI)

Acute Respiratory Distress Syndrome | Acute Lung Injury | Respiratory Distress Syndrome, Adult

United States, Canada
Kırıkkale University
TC Erciyes University

Not yet recruiting

OSA Risk Level in Dental Patients and Correlation With Complications After General Anesthesia

Postoperative Complications | Obstructive Sleep Apnea of Adult | Obstructive Sleep Apnea Risk Management | Dental Caries Under General Anesthesia
National University Hospital, Singapore

Recruiting

CARTALL: Chimeric-Antigen Receptor (CAR) T-Cell Therapy for Relapsed/ Refractory T-Lineage Acute Lymphoblastic Leukaemia

Lymphoblastic Leukemia, Acute, Childhood | Lymphoblastic Leukemia | Lymphoblastic Leukemia, Acute Adult | Lymphoblastic Leukemia in Children | CAR | CAR T-Cell-Related Encephalopathy Syndrome | Refractory Leukemia

Singapore
National University Hospital, Singapore

Recruiting

ALaCART-B: Acute Leukemia and Chimeric Antigen Receptor-T Cell Therapy for B-lymphoblastic Leukemia. (ALaCART)

Lymphoblastic Leukemia, Acute, Childhood | Lymphoblastic Leukemia | Lymphoblastic Leukemia, Acute Adult | Lymphoblastic Leukemia in Children | CAR | CAR T-Cell-Related Encephalopathy Syndrome

Singapore
MacroGenics

Active, not recruiting

MGD019 DART® Protein in Unresectable/Metastatic Cancer

Colorectal Cancer | Advanced Cancer | Prostate Cancer Metastatic | Cutaneous Melanoma | Solid Tumor, Adult | Squamous Cell Non Small Cell Lung Cancer

United States, Spain, Bulgaria, Poland, Ukraine
University of Nebraska
National Cancer Institute (NCI)

Completed

Capecitabine, Epirubicin, and Carboplatin in Treating Patients With Progressive, Unresectable, or Metastatic Cancer

Gastric Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Liver Cancer | Gallbladder Cancer | Extrahepatic Bile Duct Cancer

United States
Novo Nordisk A/S

Completed

Investigation of Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Multiple Doses of Somapacitan in Subjects With Various Degrees of Impaired Renal Function Compared to Subjects With Normal Renal Function

Growth Hormone Disorder | Growth Hormone Deficiency in Children | Adult Growth Hormone Deficiency

Germany
Mayo Clinic

Completed

Sirolimus and Vismodegib in Treating Patients With Solid Tumors or Pancreatic Cancer That is Metastatic or Cannot Be Removed By Surgery

Unspecified Adult Solid Tumor, Protocol Specific | Acinar Cell Adenocarcinoma of the Pancreas | Duct Cell Adenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage IV Pancreatic Cancer

United States
Albert Einstein College of Medicine
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Early Insulin and Development of ARDS

Hyperglycemia | Sepsis | Respiratory Distress Syndrome, Adult

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Withdrawn

Docetaxel and St. John's Wort in Treating Patients With Solid Tumors That Cannot Be Removed By Surgery

Adult Solid Tumor | Breast Cancer | Head and Neck Cancer | Kidney and Urinary Cancer | Male Reproductive Cancer | Thorax and Respiratory Cancer
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Epoetin Alfa in Treating Patients With Anemia Who Are Undergoing Chemotherapy for Cancer

Lymphoma | Leukemia | Anemia | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous Condition | Lymphoproliferative Disorder

United States
Aga Khan University
Medical Research Council, Pakistan

Completed

Inhaled Prostacyclin for Adult Respiratory Distress Syndrome (ARDS) and Pulmonary Hypertension

Pulmonary Hypertension | Adult Respiratory Distress Syndrome
Rigshospitalet, Denmark
Copenhagen University Hospital - Rigshospitalet, Department of Occupational... and other collaborators

Recruiting

The SaVe Project-Sarcopenia and Vertigo in Aging Patients With Colorectal Cancer (SaVe)

Cancer | Colorectal Cancer | Chemotherapy | Exercise | Sarcopenia | Vertigo | Rehabilitation | Elderly | Older Adults | Resistance Training | Geriatric | Chemotherapy-induced Peripheral Neuropathy | Vestibular Rehabilitation | Oncologic Complications | Comprehensive Geriatric Assessment | Frail | Postural Stability | Balance... and other conditions

Denmark

Clinical Trials on Adults

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Tanzania

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations