Clinical Trials on Advanced or Metastatic Paraganglioma/ Pheochromocytoma

Total 1813 results

National Cancer Institute (NCI)

Recruiting

Testing the Addition of an Anticancer Drug, Olaparib, to the Usual Chemotherapy (Temozolomide) for Advanced Neuroendocrine Cancer

Metastatic Adrenal Gland Pheochromocytoma | Metastatic Paraganglioma | Unresectable Adrenal Gland Pheochromocytoma | Unresectable Paraganglioma | Advanced Adrenal Gland Pheochromocytoma | Advanced Paraganglioma | Stage III Adrenal Gland Pheochromocytoma and Sympathetic Paraganglioma AJCC v8 | Stage...

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Cabozantinib S-malate in Treating Patients With Metastatic Pheochromocytomas or Paragangliomas That Cannot Be Removed by Surgery

Metastatic Adrenal Gland Pheochromocytoma | Locally Advanced Paraganglioma | Metastatic Paraganglioma | Unresectable Adrenal Gland Pheochromocytoma | Unresectable Paraganglioma | Regional Adrenal Gland Pheochromocytoma

United States
Nanjing First Hospital, Nanjing Medical University

Recruiting

A Prospective Phase II Efficacy and Safety Study of Anlotinib in Metastatic or Locally Advanced Pheochromocytoma/ Paraganglioma : Open-label Single-arm, Exploratory Trial (EASOAIPPGL)

Advanced or Metastatic Paraganglioma/ Pheochromocytoma

China
Abramson Cancer Center of the University of Pennsylvania

Completed

Dovitinib in Neuroendocrine Tumors

Unresectable Paraganglioma | Recurrent Pheochromocytoma | Advanced Metastatic Paraganglioma | Advanced Metastatic Pheochromocytoma | Recurrent Paraganglioma | Unresectable Pheochromocytoma

United States
Assistance Publique Hopitaux De Marseille

Completed

Comparison of Diagnostic Performances of 68Ga-DOTATATE PET-CT and 18F-FDOPA PET-CT in Paragangliomas and Pheochromocytomas Evaluation (DOTATATE)

Paragangliomas | Pheochromocytomas

France
Peking Union Medical College Hospital

Recruiting

The Efficacy and Safety of Anlotinib in Patients With Metastatic Pheochromocytoma or Paraganglioma

Paraganglioma, Extra-Adrenal | Malignant Adrenal Gland Pheochromocytoma | Malignant Paraganglioma | Pheochromocytoma, Metastatic | Paraganglioma, Malignant

China
Peking Union Medical College Hospital

Recruiting

Prediction and Evaluation of Anlotinib Treatment Response Using Contrast Enhanced Ultrasound PPGL Patients

Ultrasonography | Pheochromocytoma, Metastatic | Paraganglioma, Malignant | Pheochromocytoma Malignant

China
National Cancer Institute (NCI)

Terminated

Pazopanib Hydrochloride in Treating Patients With Advanced or Progressive Malignant Pheochromocytoma or Paraganglioma

Paraganglioma | Metastatic Adrenal Gland Pheochromocytoma | Recurrent Adrenal Gland Pheochromocytoma | Extra-Adrenal Paraganglioma

United States, Singapore, Hong Kong
Mayo Clinic
National Cancer Institute (NCI)

Completed

Lenvatinib in Treating Patients With Metastatic or Advanced Pheochromocytoma or Paraganglioma That Cannot Be Removed by Surgery

Metastatic Adrenal Gland Pheochromocytoma | Malignant Adrenal Gland Pheochromocytoma | Malignant Paraganglioma

United States
Peking Union Medical College Hospital

Recruiting

The Efficacy and Safety of Penpulimab in the Treatment of Metastatic PPGL Patients Who Fail to Other Systemic Treatment

Pheochromocytoma, Metastatic | Paraganglioma, Malignant | Pheochromocytoma Malignant

China
Peking Union Medical College Hospital

Completed

The Efficacy and Safety of Temozolomide in Patients With MPPGL (MPPGL)

Pheochromocytoma, Metastatic | Paraganglioma, Malignant | Pheochromocytoma Malignant

China
University College, London
AstraZeneca; Cancer Research UK

Withdrawn

Phase I Trial of Vandetanib Combined With 131I-mIBG to Treat Patients With Advanced Phaeochromocytoma and Paraganglioma (VIBRaNT)

Paraganglioma | Phaeochromocytoma

United Kingdom
Istanbul University

Completed

Magnesium and Dexmedetomidine in Pheochromocytoma

Hemodynamic Instability | Phaeochromocytoma Crisis
Gustave Roussy, Cancer Campus, Grand Paris
National Cancer Institute, France; European Network for the Study of Adrenal...

Completed

First International Randomized Study in Malignant Progressive Pheochromocytoma and Paraganglioma (FIRSTMAPPP)

Malignant Progressive Pheochromocytoma and Paraganglioma (PPGL)

Italy, France, Germany, Netherlands
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Radioactive Drug (177Lu-DOTATATE) for the Treatment of Locally Advanced, Metastatic, or Unresectable Rare Endocrine Cancers

Metastatic Adrenal Gland Pheochromocytoma | Stage III Thyroid Gland Medullary Carcinoma AJCC v8 | Stage IV Thyroid Gland Medullary Carcinoma AJCC v8 | Locally Advanced Adrenal Gland Pheochromocytoma | Locally Advanced Paraganglioma | Metastatic Paraganglioma | Metastatic Parathyroid Gland Carcinoma and other conditions

United States
University of Texas Southwestern Medical Center

No longer available

131I-Metaiodobenzylguanidine (131I-MIBG) Therapy for Relapsed/Refractory Neuroblastoma

Relapsed Neuroblastoma | Metastatic Pheochromocytoma

United States
Masonic Cancer Center, University of Minnesota

Suspended

MIBG for Refractory Neuroblastoma and Pheochromocytoma

Relapsed Neuroblastoma | Metastatic Pheochromocytoma

United States
John Maris

Available

131-I-MIBG Therapy for Refractory Neuroblastoma, Expanded Access Protocol

Neuroblastoma | Childhood Metastatic Pheochromocytoma

United States
Kunwu Yan,MM

Completed

Study of Alpha-blockers Alone During Preoperative Preparation in Patients With Pheochromocytoma

Hemodynamic | Adrenal Pheochromocytoma
Rigshospitalet, Denmark

Not yet recruiting

Development of a Predictive Model for the Risk of Metastatic Disease in PPGLs, a Retrospective Cohort Study (PPGL-Pred)

Head and Neck Cancer | Genetic Predisposition to Disease | Neuroendocrine Tumors | Pheochromocytoma | Paraganglioma | Pathology | Somatic Mutation

Denmark
National Cancer Institute (NCI)

Recruiting

Testing the Combination of Anti-Cancer Drugs Talazoparib and Temozolomide in Patients With Advanced Stage Rare Cancers, RARE 2 Trial

Malignant Solid Neoplasm | Adrenal Gland Pheochromocytoma | Paraganglioma | Hematopoietic and Lymphatic System Neoplasm

United States
Jiangsu Simcere Pharmaceutical Co., Ltd.

Unknown

Study of Metatinib Tromethamine Tablet

Advanced or Metastatic Gastric Cancer | Advanced or Metastatic CRC | Advanced or Metastatic Liver Cancer | Advanced or Metastatic Non Squamous NSCLC

China
Seoul National University Hospital

Completed

RAD001 in Pheochromocytoma or Nonfunctioning Carcinoid (PheoCarcRAD001)

Pheochromocytoma | Extra-adrenal Paraganglioma | Non-functioning Carcinoid

Korea, Republic of
Peking Union Medical College Hospital

Recruiting

A Study on the Safety and Effectiveness of Anlotinib for Neoadjuvant Treatment of PPGL

Pheochromocytoma | Paraganglioma

China
Yonsei University

Completed

Dexmedetomidine Infusion During Laparoscopic Adrenalectomy

Pheochromocytoma

Korea, Republic of
Asan Medical Center

Terminated

F-18 FDOPA PET/CT Versus I-123 MIBG Scintigraphy With SPECT/CT for the Diagnosis of Pheochromocytoma and Paraganglioma

Pheochromocytoma | Paraganglioma

Korea, Republic of
Molecular Insight Pharmaceuticals, Inc.

Approved for marketing

Expanded Access Program of Ultratrace Iobenguane I131 for Malignant Relapsed/Refractory Pheochromocytoma/Paraganglioma

Pheochromocytoma | Paraganglioma

United States
University of California, San Francisco

Completed

A Phase II Study of 131I- Metaiodobenzylguanidine (MIBG) for Treatment of Metastatic or Unresectable Pheochromocytoma and Related Tumors

Pheochromocytoma | Paraganglioma

United States
University Medical Center Groningen
Radboud University Medical Center; Maastricht University Medical Center; UMC... and other collaborators

Completed

Phenoxybenzamine Versus Doxazosin in PCC Patients (PRESCRIPT)

Pheochromocytoma

Netherlands
Vascular Biogenics Ltd. operating as VBL Therapeutics

Unknown

A Phase I Study to Assess the Safety and Distribution of VB-111 in Patients With Advanced Metastatic Cancer

Advanced and/or Metastatic Solid Organ Cancer

United States
Istituto Scientifico Romagnolo per lo Studio e...

Not yet recruiting

"Receptor Radionuclide Therapy With 177Lu-DOTATOC (LUFOR)

Neuroendocrine Tumors | Pheochromocytoma | Paraganglioma
Antonio Fojo
Ipsen

Recruiting

LAnreotide in Metastatic Pheochromocytoma / PARAganglioma (LAMPARA) (LAMPARA)

Pheochromocytoma | Paraganglioma

United States
University of Avignon
Assistance Publique Hopitaux De Marseille; Centre Hospitalier Henri Duffaut...

Terminated

Infrared Thermography Associated With Cutaneous Microcirculation for Detection of Brown-adipose Tissue (MICROBAT) (MICROBAT)

Pheochromocytoma | Paraganglioma

France
University of California, Los Angeles

Completed

Preoperative Alpha Blockade for Pheochromocytoma

Pheochromocytoma | Paraganglioma

United States
Jagiellonian University

Completed

Selective Versus Nonselective Alpha-blockade Prior to Pheochromocytoma Resection - Systematic Review and Meta-analysis

Pheochromocytoma

Poland
Sue O'Dorisio
Advanced Accelerator Applications

Withdrawn

Dosimetry Guided PRRT With 177Lu-DOTATATE in Children and Adolescents

Neuroendocrine Tumors | Pheochromocytoma | Paraganglioma

United States
University of California, San Francisco

Approved for marketing

Compassionate Use of 131I-MIBG for Patients With Malignant Pheochromocytoma

Pheochromocytoma | Paraganglioma

United States
Molecular Insight Pharmaceuticals, Inc.

Unknown

A Study Evaluating Ultratrace Iobenguane I131 in Patients With Malignant Relapsed/Refractory Pheochromocytoma/Paraganglioma

Pheochromocytoma | Paraganglioma

United States
Medical University of Vienna

Completed

Non-invasive Evaluation of Fluid Status and Cardiac Output During Operative Treatment of Pheochromcytoma

Pheochromocytoma

Austria
Akeso

Not yet recruiting

A Study to Evaluate the Safety, Pharmacokinetics, and Antitumor Activity of AK114

Metastasis | Advanced or Metastatic Solid Tumors | Malignancy

Australia
Zagazig University

Completed

Intraoperative Hemodynamic Instability in Adrenalectomy for Pheochromocytoma.

adrenalDisease
Hospices Civils de Lyon

Unknown

Surgeon-Anesthesiologist Collaboration (CCAP)

Pheochromocytoma | Collaboration

France
Peking Union Medical College Hospital

Recruiting

Prediction of Myocardial Injury After Laparoscopic Pheochromocytoma/ParaGangLioma Resection (MI-PPGL)

PGL

China
Millennium Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Relative Bioavailability, Effect of Food, and Gastric Potential Hydrogen (pH) Modification on the Pharmacokinetics of TAK-117 (MLN1117) in Healthy Participants

Neoplasm, Advanced or Metastatic
Shanghai Miracogen Inc.

Recruiting

A Study of MRG002 in Patients With HER2-Positive Advanced Solid Tumors and Locally Advanced or Metastatic Gastric/Gastroesophageal Junction (GEJ) Cancer

Advanced Solid Tumors | Advanced or Metastatic Gastric Cancer | Advanced or Metastatic Gastroesophageal Junction Cancer

United States
Memorial Sloan Kettering Cancer Center

Completed

Use of a Video Decision Tool to Improve Informed Decision-Making in Hospitalized Patients Considering Palliative Radiation Therapy

Metastatic Cancer or Locally Advanced | Patients Receiving Palliative Radiation

United States
Suzhou Kanova Biopharmaceutical Co., LTD

Not yet recruiting

Phase I of XKH002 Injection in Patients

Advanced or Metastatic Solid Tumors
Incendia Therapeutics

Recruiting

A First-in-human Study of PRTH-101 Monotherapy +/- Pembrolizumab in Subjects With Advanced Malignancies

Advanced or Metastatic Solid Tumors

United States
Takeda
Takeda Development Center Americas, Inc.

Recruiting

First-in-Human Study of TAK-280 in Participants With Unresectable Locally Advanced or Metastatic Cancer

Unresectable Locally Advanced or Metastatic Cancer

Spain, United States, Australia, Canada
Letolab

Not yet recruiting

Phase II Clinical Study of LTC004 in Patients With mCRC

Locally Advanced or Metastatic CRC

Clinical Trials on Advanced or Metastatic Paraganglioma/ Pheochromocytoma

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