Clinical Trials on Advanced HCC Treated by Systemic Immunotherapy

Total 9383 results

Valérie LAURENT

Completed

CT Perfusion Parameters for Advanced HCC Treated by Systemic Immunotherapy

Advanced HCC Treated by Systemic Immunotherapy

France
West China Hospital

Recruiting

Combination of Sintilimab and Stereotactic Body Radiotherapy in Advanced Metastatic HCC

Immunotherapy | SBRT | Stage IV HCC

China
Sun Yat-sen University

Not yet recruiting

Sintilimab Plus Bevacizumab as Adjuvant Therapy in HCC Patients at High Risk of Recurrence After Curative Resection (DaDaLi)

HCC | Immunotherapy | Adjuvant Therapy

China
Hannover Medical School

Completed

Elimination of CD4+CD25+ Regulatory T Cells in Patients With Hepatocellular Carcinoma

Advanced HCC

Germany
Egyptian Liver Hospital

Completed

Clinical Impacts of Achieving SVR in Patients With Advanced Hepatic Fibrosis Related to Chronic HCV Treated With Direct Acting Antivirals

HCC in Chronic HCV Patients With Advanced Liver Fibrosis
Guangzhou FineImmune Biotechnology Co., LTD.

Recruiting

Phase I Clinical Study of Tumor-associated Lymph Node T Cell Therapy for Advanced Solid Tumors (TAL-T)

Advanced Solid Tumor | Immunotherapy | Tumor Associated Lymph Node T Cell

China
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Study to Evaluate SHR-1210 in Combination With Apatinib as First-Line Therapy in Patients With Advanced HCC

Locally Advanced or Metastatic and Unresectable HCC

United States, Spain, China, Taiwan, Belgium, Korea, Republic of, Italy, Hong Kong, Russian Federation, Ukraine, Turkey, Poland, Germany
Shen Lin

Recruiting

Prospectively Predict the Efficacy of Treatment of Gastrointestinal Tumors Based on Peripheral Multi-omics Liquid Biopsy

Immunotherapy | Advanced Gastric Adenocarcinoma

China
Shanghai International Medical Center

Unknown

Precision Cell Immunotherapy Combined With Chemotherapy in Advanced Gastric Cancer

Chemotherapy | Advanced Malignancies | Precision Cell Immunotherapy

China
Shanghai Juncell Therapeutics
Shanghai 10th People's Hospital

Recruiting

Study on TIL for the Treatment of Advanced Hepatobiliary-Pancreatic Cancers

Treatment Side Effects | Effects of Immunotherapy | Advanced Liver Cancers | Tumor Infiltrating Lymphocyte | Advanced Pancreatic Cancers

China
Ningbo Cancer Hospital

Unknown

Precision Cell Immunotherapy Combined With TACE in Advanced Liver Cancer

Advanced Liver Cancer | Precision Cell Immunotherapy | Transcatheter Arterial Chemoembolization

China
Jiangsu Alphamab Biopharmaceuticals Co., Ltd
Sunshine Lake Pharma Co., Ltd.

Terminated

KN046 Combined With Ningatinib in the Treatment of Advanced Hepatocellular Carcinoma

Advanced HCC

China
Lin Chen

Completed

Prospectively Predict the Immunotherapy Response of Gastric Cancer Based on Circulating Exosomal LncRNA-GC1 Biopsy

Immunotherapy | Advanced Gastric Carcinoma

China
Betta Pharmaceuticals Co., Ltd.

Not yet recruiting

A Phase 1 Study of BPI-371153 in Subjects With Advanced Solid Tumors or Relapsed/Refractory Lymphoma

Lymphoma | HCC | NSCLC | Advanced Solid Tumor

China
Shanghai Junshi Bioscience Co., Ltd.

Active, not recruiting

Evaluate the Safety and Efficacy of Toripalimab Combined With Bevacizumab Versus Sorafenib Therapy for HCC

Advanced Hepatocellular Carcinoma (HCC)

China, Singapore
Astellas Pharma Inc

Terminated

A Randomized, Placebo-controlled, Double-blind Phase 2 Study With OSI-906 in Patients With Advanced HCC

Advanced Hepatocellular Carcinoma (HCC)

Korea, Republic of, Belgium, United States, Hong Kong, Singapore, Taiwan, Germany, Spain, France, Italy
Genentech, Inc.

Recruiting

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7502175 as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors

Melanoma | Cervical Cancer | HCC | Gastric Cancer | Esophageal Cancer | NSCLC | Urothelial Carcinoma | HNSCC | Locally Advanced or Metastatic Solid Tumors | TNBC | Clear Cell RCC

Korea, Republic of, Netherlands, Spain, United States, Australia, Canada, Belgium
Zhejiang Haichang Biotech Co., Ltd.

Not yet recruiting

Phase 2 Study of WGI-0301 in Combination With Sorafenib for Advanced HCC

Advanced Hepatocellular Carcinoma (HCC)
Peking University Cancer Hospital & Institute

Recruiting

The Comparison Between HepaSphere Drug-eluting Bead Transarterial Chemoembolization Combined With Hepatic Arterial Infusion Chemotherapy in Advanced Hepatocellular Carcinoma

Advanced Hepatocellular Carcinoma (HCC)

China
Shanghai Junshi Bioscience Co., Ltd.

Active, not recruiting

Phase III Study of Toripalimab（JS001） Combined With Lenvatinib for Advanced HCC

Advanced Hepatocellular Carcinoma (HCC)

Italy, Poland, Singapore, United States, China, Ukraine
Shanghai Juncell Therapeutics

Recruiting

A Phase I Study on Autologous Tumor Infiltrating Lymphocytes Injection (GC101 TIL) for the Treatment of Advanced Malignant Solid Tumors (MIZAR-001)

Advanced Solid Tumor | Efficacy | Immunotherapy | Adverse Drug Event | Safety | Tumor Infiltrating Lymphocytes

China
Ningbo Cancer Hospital

Unknown

Precision Cell Immunotherapy Combined With Chemotherapy in Advanced Gastric Cancer

Chemotherapy | Advanced Gastric Cancer | Precision Cell Immunotherapy

China
Sidney Kimmel Cancer Center at Thomas Jefferson...
Pfizer

Active, not recruiting

A Clinical Research Study to Determine Whether PD 0332991 May Be Effective in Treating Patients With Liver Cancer

HCC | Advanced Hepatocellular Carcinoma | Liver Cancer

United States
Zai Lab (Shanghai) Co., Ltd.

Terminated

MGD013 Monotherapy and Combination With Brivanib Dose Escalation and Expansion Study in Advanced Liver Cancer Patients

Advanced Hepatocellular Carcinoma (HCC)

China
Beijing Shenogen Biomedical Co., Ltd
The First Affiliated Hospital with Nanjing Medical University; Guilin Medical... and other collaborators

Unknown

The Phase III Study of Icaritin Versus HUACHANSU PIAN in Hepatocellular Carcinoma Subjects

Advanced HBV-Related Hepatocellular Carcinoma (HCC)

China
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

A Phase III Clinical Trial of AK105 Injection Combined With Anlotinib Hydrochloride Capsules Versus Sorafenib in Subjects With Advanced Hepatocellular Carcinoma (HCC)

Advanced Hepatocellular Carcinoma (HCC)

China
Jiangsu HengRui Medicine Co., Ltd.

Terminated

A Study of Camrelizumab Combined With Rivoceranib Mesylate Versus Investigator's Choice of Regimen in Treatment of Patients With Advanced Hepatocellular Carcinoma (HCC)

Advanced Hepatocellular Carcinoma (HCC)

China
Abramson Cancer Center of the University of Pennsylvania

Completed

Galunisertib (LY2157299) Plus Stereotactic Body Radiotherapy (SBRT) in Advanced Hepatocellular Carcinoma (HCC)

ADVANCED HEPATOCELLULAR CARCINOMA (HCC)

United States
Shanghai Junshi Bioscience Co., Ltd.

Active, not recruiting

A Single-arm, Open-label, Multi-center Phase II Clinical Study to Evaluate the Safety and Efficacy of Toripalimab Injection (JS001) Combined With Bevacizumab as the First-line Therapy for Advanced Hepatocellular Carcinoma (HCC)

Advanced Hepatocellular Carcinoma (HCC)

China
Shin Kong Wu Ho-Su Memorial Hospital

Completed

The Safety and Maximum Tolerated Dose of Axitinib in Combination With Radiotherapy for HCC

Advanced Hepatocellular Carcinoma (HCC)

Taiwan
Shenzhen SiBiono GeneTech Co.,Ltd

Unknown

Trans-catheter Arterial Embolization Combined With p53 Gene Therapy for Treatment of Advanced Hepatocellular Carcinoma

Advanced Hepatocellular Carcinoma (HCC)

China
Chugai Pharmaceutical

Completed

A Phase I Study of GC33 in Advanced or Metastatic Liver Cancer (Hepatocellular Carcinoma)

Advanced or Metastatic HCC

United States
Bispebjerg Hospital

Unknown

Laser Immunotherapy With and Without Topical Anti-PD1 in Basal Cell Carcinomas

Immune Response | Immunotherapy | BCC - Basal Cell Carcinoma | Ablative Fractionated Laser

Denmark
Hospices Civils de Lyon

Unknown

ASIA Study : French Register of Inflammatory Eye Disease (ASIA)

Patients Treated for Cancer by Immunotherapy

France
Shanghai Juncell Therapeutics
Shanghai 10th People's Hospital

Recruiting

Study on TIL for the Treatment of Advanced Breast Cancer

Breast Cancer | Advanced Breast Cancer | Treatment Side Effects | Effects of Immunotherapy

China
Daiichi Sankyo, Inc.

Terminated

An Open Study Assessing the Safety and Tolerability of U3-1784

Advanced Solid Tumors | Hepatocellular Cancer (HCC)

United Kingdom
AIPING ZHOU

Not yet recruiting

SOX Combined With Sintilimab and Trastuzumab Versus SOX Regimen in the Perioperative Treatment of HER2-positive Locally Advanced Gastric Adenocarcinoma

Immunotherapy | Sintilimab | Locally Advanced Solid Tumor | Oxaliplatin | HER2-positive | Gastric or Gastroesophageal Junction Adenocarcinoma | S-1

China
Jiangsu HengRui Medicine Co., Ltd.

Suspended

Safety, Tolerability and Pharmacokinetics/Pharmacodynamics (PK/PD) of SHR-1603 in Subjects With Advanced Malignancies

Neoplasms by Histologic Type | Lymphoma | Hematologic Neoplasms | Advanced Cancer | Immunotherapy | Physiological Effects of Drugs

China
Azienda Ospedaliera Specializzata in Gastroenterologia...
Dr. Raffaele Cozzolongo; Dr. Palma Aurelia Iacovazzi; Dr. Vito Giannuzzi; Dr. Francesco... and other collaborators

Recruiting

Use of Blood Biomarkers for the Early Diagnosis of Hepatocellular Carcinoma (HCC) (GALAD)

HCC | NAFLD | HBV | Cirrhosis, Liver | HCV

Italy
Fujian Medical University

Not yet recruiting

Study Evaluating Neoadjuvant Immunotherapy Increasing CD8+ Cell Infiltration in Advance Gastric Adenocarcinoma

Advanced Gastric Carcinoma | Neoadjuvant Immunotherapy | CD8+ Tumor Infiltrating Lymphocytes
Ningbo Cancer Hospital

Unknown

Precision Cell Immunotherapy Combined With Chemotherapy in Advanced Lung Cancer

Chemotherapy | Advanced Lung Cancer | Precision Cell Immunotherapy

China
Hubei Cancer Hospital

Recruiting

Primary Tumor Radiotherapy Omitting CTV for Patients With Advanced NSCLC Responded to Immunotherapy and Chemotherapy

Radiotherapy | Immunotherapy | Advanced Non-Small Cell Squamous Lung Cancer

China
Icahn School of Medicine at Mount Sinai

Completed

Post Sustained Virological Response (SVR) Hepatocellular Carcinoma (HCC) Screening

HCC | Hepatocellular Carcinoma | Hepatitis C | HCV

United States
Leiden University Medical Center
Mirada Medical

Completed

Intraprocedural Assessment of Ablation Margins Using Computed Tomography Co-registration in Primary Liver Tumor Treatment With Percutaneous Ablation (IAMCOMPLETE)

HCC

Netherlands
Indiana University
BTG International Inc.

Terminated

A Study to Assess the Effect of Y-90 Therapy on Non-target/Background Liver

HCC | Liver Cancer

United States
BeiGene

Completed

Study of BGB-A317 in Participants With Previously Treated Unresectable HCC

Hepatocellular Carcinoma (HCC)

Spain, China, Taiwan, Germany, Italy, United Kingdom, France, Poland
Michael Dill
University of Cologne; German Cancer Research Center; Heidelberg University; Universitätsmedizin... and other collaborators

Not yet recruiting

Fecal Microbiota Transfer in Liver Cancer to Overcome Resistance to Atezolizumab/Bevacizumab (FLORA) (FLORA)

Immunotherapy

Germany
Gustave Roussy, Cancer Campus, Grand Paris

Unknown

Randomized Trial Of Platelet Transfusion Policies After Blood Stem Cells Transplantation In Young Children: Reduction Of Number Of Single Platelet Concentrate Donors Per Child

Children Treated With High-Dose Chemotherapy (HDC) Followed by Haematopoietic Stem Cell Transplantation (HSCT)

France
Lei Li

Completed

Immunotherapy for Recurrent Cervical Cancer Refractory to Platinum-based Chemotherapy

Chemotherapy | Recurrent Cervical Carcinoma | Immunotherapy | Anti-PD-1 Antibody | Persistent Advanced Cervical Carcinoma

China
The University of Hong Kong
Education University of Hong Kong

Recruiting

Artificial Intelligence vs. LIRADS in Diagnosing HCC on CT

HCC | Liver Cancer

Hong Kong

Clinical Trials on Advanced HCC Treated by Systemic Immunotherapy

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