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Clinical Trials on Advanced KRAS G12D Mutant Solid Tumors in United Kingdom
Total 1032 results
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Ikena OncologyGilead SciencesTerminatedBreast Cancer | Head and Neck Cancer | Gynecologic Cancer | Colorectal Cancer | Pancreatic Cancer | Gastric Adenocarcinoma | Lung Adenocarcinoma | Advanced Solid TumorUnited States
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University of California, DavisNational Cancer Institute (NCI)RecruitingAnatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Advanced Malignant Solid Neoplasm | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage III Renal Cell Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8 | Clinical Stage III Cutaneous Melanoma... and other conditionsUnited States
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7 Hills Pharma, LLCRecruitingMelanoma | Kidney Cancer | Renal Cell Carcinoma | Hepatocellular Carcinoma | Colorectal Cancer | NSCLC | Non Small Cell Lung Cancer | Skin Cancer | Metastasis | Advanced Solid Tumor | Advanced Cancer | Renal Cell Cancer | Hepatocellular Cancer | Mismatch Repair Deficiency | Pleural Mesothelioma | MSI-High | Anaplastic Lymphoma... and other conditionsUnited States
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Epizyme, Inc.CompletedSolid Tumor | Mesothelioma | Rhabdoid Tumor | Hematologic Malignancy | Advanced Malignancies | Synovial Sarcoma | Renal Medullary Carcinoma | Diffuse Large B-Cell Lymphoma (DLBCL) | Follicular Lymphoma (FL) | Non-Hodgkin Lymphoma (NHL) | All Malignancies | Epithelioid Sarcoma (ES)Spain, United States
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SynthekineRecruitingRenal Cell Carcinoma | Cervical Cancer | Gastric Cancer | Non Small Cell Lung Cancer | Advanced Solid Tumor | Head and Neck Squamous Cell Carcinoma | Urothelial Carcinoma | Microsatellite Instability High | Malignant Melanoma | GastroEsophageal Cancer | Mismatch Repair DeficiencyUnited States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingAdvanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Metastatic Skin Squamous Cell Carcinoma | Unresectable Solid Neoplasm | Metastatic Kidney Medullary Carcinoma | Metastatic Penile Carcinoma | Small Cell Carcinoma | Metastatic Adrenal Gland Pheochromocytoma | Stage IV Penile Cancer... and other conditionsUnited States
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Fate TherapeuticsCompletedMelanoma | Renal Cell Carcinoma | Hepatocellular Carcinoma | Colorectal Cancer | Pancreatic Cancer | Non Small Cell Lung Cancer | Advanced Solid Tumors | HER2-positive Breast Cancer | Head and Neck Squamous Cell Carcinoma | HER2 Positive Gastric Cancer | EGFR Positive Solid TumorUnited States
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Tesaro, Inc.Active, not recruitingNeoplasms | Solid Tumor | Non Small Cell Lung Cancer | Metastatic Cancer | Advanced Cancer | Non Small Cell Lung Cancer Stage IIIB | Non Small Cell Lung Cancer MetastaticUnited States
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Sonnet BioTherapeuticsHoffmann-La RocheRecruitingAdvanced Solid Tumor | Platinum-resistant Ovarian CancerUnited States, Australia
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AbbVieRecruitingColorectal Cancer | Non-Small Cell Lung Cancer | Advanced Solid Tumors | Gastroesophageal AdenocarcinomaUnited States, Japan, Puerto Rico, Taiwan, Spain, Australia, France, Israel, Korea, Republic of, Poland
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Compass TherapeuticsIqvia Pty Ltd; Merck, Sharp & Dohme, LLC, Rahway, NJ USARecruitingMelanoma | Head and Neck Cancer | Small Cell Lung Cancer | Metastatic Cancer | Mesothelioma | Non-small Cell Lung Cancer | Locally Advanced Solid TumorUnited States
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AbbVieCompletedAdvanced Solid Tumors | Squamous Cell Carcinoma of the Head and Neck | Undifferentiated Pleomorphic Sarcoma | Carcinoma of the BreastUnited States, France, Spain
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Memorial Sloan Kettering Cancer CenterRecruitingMelanoma | Solid Tumor | Metastatic Cancer | Advanced Cancer | Head and Neck Squamous Cell Carcinoma | Kaposi Sarcoma | Merkel Cell Carcinoma | Angiosarcoma | Basal Cell Carcinoma | Extramammary Paget Disease | HNSCC | Refractory Cancer | Cutaneous Squamous Cell Carcinoma | BCC | Adnexal Carcinoma | BCC - Basal Cell Carcinoma and other conditionsUnited States
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NextCure, Inc.TerminatedBreast Cancer | Ovarian Cancer | Non-small Cell Lung Cancer | Advanced or Metastatic Solid TumorsUnited States
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Brown UniversityTaiho Oncology, Inc.RecruitingSoft Tissue Sarcoma | Advanced Breast Cancer | SCLC | Bladder Cancer | Endometrial Cancer | Treatment-Refractory Solid Tumors | Retinoblastoma DeficiencyUnited States
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Fusion Pharmaceuticals Inc.AstraZenecaNot yet recruitingAdvanced Solid Tumor | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Pancreatic Ductal Adenocarcinoma | Metastatic Colorectal CarcinomaUnited States, Canada
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MacroGenicsTerminatedMelanoma | Non Small Cell Lung Cancer | Squamous Cell Carcinoma of Head and Neck | Triple Negative Breast Cancer | Metastatic Castrate Resistant Prostate Cancer | Advanced Solid Tumor, AdultSpain, United States, Australia, Poland
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Elevation OncologyActive, not recruitingSarcoma | Kidney Cancer | Breast Cancer | Head and Neck Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Lung Cancer | Prostate Cancer | Cholangiocarcinoma | Bile Duct Cancer | Bladder Cancer | Metastatic Solid Tumor | Gallbladder Cancer | Uterine Cancer | Locally Advanced Solid TumorUnited States, Korea, Republic of, Australia, Canada
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National Cancer Institute (NCI)Active, not recruitingHIV Infection | Metastatic Renal Cell Carcinoma | Anatomic Stage III Breast Cancer AJCC v8 | Recurrent Ovarian Carcinoma | Metastatic Lung Non-Small Cell Carcinoma | Anatomic Stage IV Breast Cancer AJCC v8 | Metastatic Melanoma | Recurrent Head and Neck Carcinoma | Recurrent Renal Cell Carcinoma | Advanced... and other conditionsUnited States
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Children's Oncology GroupNational Cancer Institute (NCI); Incuron LLCRecruitingRefractory Lymphoma | Refractory Malignant Solid Neoplasm | Recurrent Lymphoma | Recurrent Malignant Solid Neoplasm | Recurrent Osteosarcoma | Refractory Osteosarcoma | Diffuse Midline Glioma, H3 K27M-Mutant | Recurrent Diffuse Intrinsic Pontine Glioma | Metastatic Malignant Neoplasm in the Central... and other conditionsUnited States
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BicycleTx LimitedRecruitingCarcinoma, Non-Small-Cell Lung | Triple Negative Breast Neoplasms | Advanced Solid Tumor | Ovarian Neoplasm | Urinary Bladder NeoplasmUnited States, United Kingdom, France, Spain, Italy, Canada
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)RecruitingPrognostic Stage IIIC Breast Cancer AJCC v8 | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Melanoma | Stage IV Lung Cancer AJCC v8 | Locally Advanced Malignant Solid Neoplasm | Locally... and other conditionsUnited States
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NeoImmuneTechMerck Sharp & Dohme LLCActive, not recruitingSmall Cell Lung Cancer | Pancreatic Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Triple Negative Breast Cancer | Microsatellite Stable Colorectal Cancer | Any Advanced Solid TumorsUnited States
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Valerio TherapeuticsRecruitingBreast Cancer | Prostate Cancer | Advanced or Metastatic Solid Tumors | Recurrent Ovarian CancerUnited States
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NextCure, Inc.TerminatedGastric Cancer | Ovarian Cancer | Colo-rectal Cancer | Advanced or Metastatic Solid TumorsUnited States
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BicycleTx LimitedRecruitingHead and Neck Cancer | Ovarian Cancer | Triple Negative Breast Cancer | Non-small Cell Lung Cancer | Advanced Solid Tumor Historically Known for High EphA2 Expression | Urothelial Cancer | Gastric/Upper Gastrointestinal CancerUnited States, Belgium, Korea, Republic of, Spain, United Kingdom
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Merck Sharp & Dohme LLCRecruitingCervical Cancer | Small Cell Lung Carcinoma | Neuroendocrine Tumor | Advanced Solid Tumors | Mesothelioma | Vulvar Cancer | Cholangiocarcinoma | Bile Duct Cancer | Endometrial Cancer | Advanced Cancer | Cervical Carcinoma | Endometrial Carcinoma | Thyroid Carcinoma | Thyroid Cancer | Anal Cancer | Colorectal Carcinoma | Carcinoid... and other conditionsCanada, France, Germany, Italy, Mexico, Netherlands, Poland, Russian Federation, Taiwan, United States, Brazil, Colombia, Israel, Korea, Republic of, Norway, Philippines, South Africa, Spain, Australia, Denmark, Chile, Portugal, Peru
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Taiho Oncology, Inc.RecruitingPancreatic Cancer | Esophageal Adenocarcinoma | Esophageal Squamous Cell Cancer | Locally Advanced Unresectable or Metastatic Solid Tumors Including Esophageal Cancer | Siewert Type 1 GEJ CancerUnited States, Spain, Germany, France
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M.D. Anderson Cancer CenterRecruitingStage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Advanced Malignant Solid Neoplasm | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage III Renal Cell Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Clinical Stage III Cutaneous Melanoma AJCC v8 and other conditionsUnited States
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Fox Chase Cancer CenterCompletedUnspecified Adult Solid Tumor, Protocol Specific | Advanced Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer | Recurrent Extrahepatic Bile Duct Cancer | Adult Primary Hepatocellular Carcinoma | Metastatic Extrahepatic Bile Duct Cancer | Stage D Adult Primary Liver Cancer (BCLC)United States
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Mayo ClinicNational Cancer Institute (NCI)RecruitingMetastatic Lung Non-Small Cell Carcinoma | Refractory Lung Non-Small Cell Carcinoma | Metastatic Melanoma | Stage IV Lung Cancer AJCC v8 | Unresectable Malignant Solid Neoplasm | Recurrent Head and Neck Squamous Cell Carcinoma | Metastatic Malignant Solid Neoplasm | Unresectable Melanoma | Clinical... and other conditionsUnited States
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Genzada Pharmaceuticals USA, Inc.Translational Drug DevelopmentActive, not recruitingSarcoma | Lymphoma | Breast Cancer | Gastric Cancer | Pancreatic Cancer | Solid Tumor | Cutaneous T-cell Lymphoma | Advanced Cancer | Head and Neck Squamous Cell Carcinoma | Colo-rectal Cancer | Cutaneous T Cell Lymphoma | Prostate Cancer Metastatic | Basal Cell Carcinoma | Solid Carcinoma | Solid Carcinoma of Stomach | Cancer of Stomach and other conditionsUnited States
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Revolution Medicines, Inc.RecruitingAdvanced Solid Tumors | Non-small Cell Lung Cancer (NSCLC) | Pancreatic Ductal Adenocarcinoma (PDAC) | Colorectal Cancer (CRC)United States
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NextCure, Inc.CompletedMelanoma | Breast Cancer | Lung Cancer | Cholangiocarcinoma | Endometrial Cancer | Head and Neck Squamous Cell Carcinoma | Urothelial Carcinoma | Advanced or Metastatic Solid Tumors | CRCUnited States
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MacroGenicsRecruitingRenal Cell Carcinoma | Advanced Solid Tumor | Epithelial Ovarian Cancer | Hepatocellular Cancer | Malignant Melanoma | Pancreatic Ductal Carcinoma | Castration-Resistant Prostatic CancerUnited States
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Revolution Medicines, Inc.RecruitingAdvanced Solid Tumors | Non-small Cell Lung Cancer (NSCLC) | Pancreatic Ductal Adenocarcinoma (PDAC) | Colorectal Cancer (CRC)United States
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BeiGeneActive, not recruitingNon Small Cell Lung Cancer | Advanced Solid Tumor | Head and Neck Squamous Cell Carcinoma (HNSCC) | Nasopharyngeal Carcinoma (NPC)Canada, Australia, New Zealand, Korea, Republic of, United States, Malaysia, Thailand
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Marengo Therapeutics, Inc.RecruitingNeoplasms | Urogenital Neoplasms | Neoplasms by Site | Carcinoma | Epstein-Barr Virus Infections | Advanced Solid Tumors | Vulvar Neoplasms | Vulvar Diseases | Abdominal Neoplasm | Lung Neoplasm | Papillomavirus Infection | Genital Neoplasm, FemaleUnited States, Canada
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Novita Pharmaceuticals, Inc.Translational Drug DevelopmentCompletedBreast Cancer | Lung Cancer | Prostate Cancer | Colon Cancer | Pancreas Cancer | Liver Cancer | Ovary Cancer | Esophagus Cancer | Advanced or Metastatic Treatment-refractory Solid Tumor MalignanciesUnited States
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Day One Biopharmaceuticals, Inc.RecruitingMelanoma | Colorectal Cancer | Solid Tumor | Non Small Cell Lung Cancer | Bladder Cancer | Thyroid Cancer, Papillary | Pilocytic Astrocytoma | Bladder Urothelial Carcinoma | Non-Small Cell Adenocarcinoma | MEK Mutation | RAS Mutation | Pancreatic Acinar Carcinoma | RAF Mutation | CRAF Gene Amplification | RAF1 Gene Amplification and other conditionsUnited States, Canada, Korea, Republic of, Spain, Australia, Belgium, France
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Fog Pharmaceuticals, Inc.RecruitingCancer | Gastric Cancer | Colorectal Cancer | Solid Tumor | Metastatic Cancer | Adenomatous Polyposis Coli | Non-small Cell Lung Cancer | Non-small Cell Lung Cancer Metastatic | Non-small Cell Carcinoma | Locally Advanced Solid Tumor | Non-small Cell Lung Cancer Stage IIIB | Gastroesophageal-junction Cancer | Non-Small... and other conditionsUnited States
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Wake Forest University Health SciencesCompletedUnspecified Childhood Solid Tumor, Protocol Specific | Pseudomyxoma Peritonei | Stage IV Ovarian Epithelial Cancer | Stage IV Ovarian Germ Cell Tumor | Ovarian Sarcoma | Recurrent Ovarian Epithelial Cancer | Stage IV Colon Cancer | Recurrent Colon Cancer | Carcinoma of the Appendix | Ovarian Stromal Cancer and other conditionsUnited States
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Daiichi SankyoMerck Sharp & Dohme LLCRecruitingMelanoma | Cervical Cancer | Head and Neck Cancer | Gastric Cancer | Esophageal Cancer | Prostate Cancer | Bladder Cancer | Advanced Solid Tumor | Endometrial Cancer | Ovarian Carcinoma | Pancreatic CarcinomaUnited States, Taiwan, Japan
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National Cancer Institute (NCI)Active, not recruitingHIV Infection | Hepatocellular Carcinoma | Non-Hodgkin Lymphoma | Metastatic Lung Non-Small Cell Carcinoma | Metastatic Melanoma | Kaposi Sarcoma | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Locally Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Unresectable... and other conditionsUnited States
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M.D. Anderson Cancer CenterActive, not recruitingMalignant Solid Neoplasm | Metastatic Lung Non-Small Cell Carcinoma | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Metastatic Melanoma | Stage III Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Unresectable Melanoma | Clinical Stage III Cutaneous... and other conditionsUnited States
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National Cancer Institute (NCI)Active, not recruitingStage III Cutaneous Melanoma AJCC v7 | Stage IV Cutaneous Melanoma AJCC v6 and v7 | Advanced Malignant Solid Neoplasm | Stage IIIC Cutaneous Melanoma AJCC v7 | Stage III Renal Cell Cancer AJCC v7 | Stage IV Renal Cell Cancer AJCC v7 | Stage IIIA Cutaneous Melanoma AJCC v7 | Stage IIIB Cutaneous Melanoma... and other conditionsUnited States
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Rahul AggarwalXynomic Pharmaceuticals, Inc.CompletedStage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Metastatic Melanoma | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Locally Advanced Melanoma | Metastatic Malignant Solid Neoplasm | Metastatic Urothelial... and other conditionsUnited States
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Revolution Medicines, Inc.Active, not recruitingAdvanced Solid Tumor | Pancreatic Ductal Adenocarcinoma | Non-Small Cell Lung Cancer (NSCLC) | Colorectal Cancer (CRC)United States, Spain, France, Korea, Republic of, Malaysia, Taiwan, Italy, Thailand, Australia, Czechia, Singapore, Poland, Serbia
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Mayo ClinicRecruitingMetastatic Renal Cell Carcinoma | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Anatomic Stage IIIC Breast Cancer AJCC v8 | Prognostic Stage III Breast Cancer AJCC v8 | Prognostic Stage IIIA Breast Cancer AJCC v8 and other conditionsUnited States
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PfizerTerminatedGastric Cancer | Non Small Cell Lung Cancer | Advanced Solid Tumors | Gastroesophageal Junction Cancer | Urothelial Cancer | Head and Neck Squamous Cell CarcinomasUnited States, Japan