Clinical Trials on Advanced Multiple Sclerosis in Belgium

Total 696 results

Marie D'hooghe

Completed

The Effect of Covid-19 on the Disease Course of Multiple Sclerosis :Belgian Lessons Learned From Rocky I to Rocky IV (TofCoMS)

COVID-19

Belgium
Biogen

Completed

Open-Label Study to Assess the Effect of Long-Term Prolonged-Release Fampridine (BIIB041) on Quality of Life as Reported by Participants With Multiple Sclerosis (ENABLE)

Multiple Sclerosis

France, Italy, United Kingdom, Germany, Australia, Belgium, Netherlands, Portugal, Denmark
Biogen

Terminated

Efficacy and Safety of BIIB033 (Opicinumab) as an Add-on Therapy to Disease-Modifying Therapies (DMTs) in Relapsing Multiple Sclerosis (MS) (AFFINITY)

Multiple Sclerosis

United States, Italy, Spain, Belgium, Germany, Switzerland, Australia, Hungary, France, Poland, United Kingdom, Czechia, Israel, Canada, Netherlands
Hoffmann-La Roche

Active, not recruiting

A Rollover Study to Evaluate the Long-Term Safety and Efficacy of Ocrelizumab In Patients With Multiple Sclerosis (OLERO)

Multiple Sclerosis

United States, Spain, Austria, Czechia, Italy, Hungary, Australia, Portugal, Serbia, Canada, Germany, United Kingdom, Poland, Romania, Croatia, Israel, Belgium, Bulgaria, Estonia, Switzerland, Mexico, Lithuania, New Zealand, France, Slo... and more
GRIN Therapeutics, Inc.

Recruiting

A Study of Radiprodil on Safety, Tolerability, Pharmacokinetics, and Effect on Seizures and Behavioral Symptoms in Patients With TSC or FCD Type II

Tuberous Sclerosis Complex | Focal Cortical Dysplasia

Spain, United Kingdom, Australia, Belgium, Canada, Italy, Poland
University Hospital, Ghent
University Ghent; Het Lezerscollectief

Completed

Evaluation of Bibliotherapy by Students and Patients With Cancer

Acute Leukemia | Advanced Solid Tumor

Belgium
Exscientia AI Limited
GT Apeiron LLC

Recruiting

Study to Assess GTAEXS617 in Patients With Advanced Solid Tumors (ELUCIDATE)

Advanced Solid Tumor

United Kingdom, Belgium
Merck KGaA, Darmstadt, Germany

Completed

Evaluation of Quality of Life (QoL) in Subjects With Highly Active Relapsing Multiple Sclerosis (MS) (CLARIFY MS)

Multiple Sclerosis

Hungary, Belgium, Portugal, Slovakia, France, Finland, Poland, Denmark, Czechia, Spain, United Kingdom, Italy, Austria, Greece, Lithuania, Netherlands, Norway, Sweden
Biogen

Completed

Avonex-evaluation of Quality of Life and Convenience in Belgian Participants - The AVAIL Study (AVAIL)

Multiple Sclerosis

Belgium
Bristol-Myers Squibb

Completed

An Investigational Immunotherapy Study of BMS-986310 Administered Alone and in Combination With Nivolumab in Patients With Advanced Solid Tumors

Advanced Cancer

United States, Belgium, Canada
Lupin Ltd.

Completed

A Study of LNP3794 in Subjects With NRAS/KRAS Mutated Advanced or Metastatic Refractory Solid Tumors

NRAS/KRAS Mutated Advanced or Metastatic Refractory Solid Tumors

United Kingdom, Netherlands, Belgium
Université Catholique de Louvain

Recruiting

Emotions and Cognitions in Pediatric Chronic Physical Conditions (EmCog)

Multiple Chronic Conditions

Belgium
Allergan

Completed

Safety and Efficacy Study of OnabotulinumtoxinA for the Treatment of Urinary Incontinence Due to Neurogenic Detrusor Overactivity (NDO) in Non-Catheterizing Patients With Multiple Sclerosis (MS)

Multiple Sclerosis | Urinary Incontinence | Neurogenic Bladder

France, Poland, Portugal, Belgium, Canada, Russian Federation, Czechia, United States
QurAlis Corporation

Recruiting

A Study Evaluating the Safety and Tolerability of QRL-201 in ALS

Amyotrophic Lateral Sclerosis

Canada, Germany, Netherlands, Ireland, United Kingdom, Belgium
Teva Pharmaceutical Industries, Ltd.

Completed

Clinical Trial of Glatiramer Acetate in Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis

Belgium, France, Germany, Israel, Italy, United Kingdom
Eli Lilly and Company

Completed

A Study of LY3434172, a PD-1 and PD-L1 Bispecific Antibody, in Advanced Cancer

Advanced Cancer

Belgium, United States, Korea, Republic of, Australia, France
Xenothera SAS

Recruiting

FIH XON7 in Advanced/Metastatic Solid Tumors (FIPO23)

Metastatic Cancer | Advanced Solid Tumor

France, Belgium
Stichting TRICALS Foundation
Research Foundation Flanders; Stichting ALS Nederland; Fight MND; MNDA; Thierry Latran... and other collaborators

Recruiting

Platform Trial to Assess the Efficacy of Multiple Drugs in Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis

Belgium, Netherlands, United Kingdom, Sweden, Spain, Australia
Hoffmann-La Roche

Completed

Safety Extension Study of TRO19622 in ALS

Amyotrophic Lateral Sclerosis

Belgium, France, Germany, Spain, United Kingdom
T-knife GmbH

Terminated

A Phase 1/ 2, First-in-Human, Open-Label, Accelerated-Titration, Two-Part Clinical Trial of TK-8001 in Patients With HLA-A*02:01 Genotype and Advanced-Stage/ Metastatic MAGE-A1+ Solid Tumors (IMAG1NE)

Advanced Solid Tumors

Germany, Belgium, Spain, Netherlands, United Kingdom
University Hospital, Ghent

Completed

High Dose Simplified Folfiri in Advanced Colorectal Cancer: a Multicentre Phase II Study

Advanced Colorectal Cancer

Belgium
Novartis Pharmaceuticals

Completed

A Placebo-controlled Study of Efficacy & Safety of 2 Trough-ranges of Everolimus as Adjunctive Therapy in Patients With Tuberous Sclerosis Complex (TSC) & Refractory Partial-onset Seizures (EXIST-3)

Tuberous Sclerosis Complex-associated Refractory Seizures

United States, Colombia, Belgium, France, Japan, Taiwan, Turkey, Spain, Thailand, Korea, Republic of, Australia, Hungary, United Kingdom, Canada, Norway, Germany, Italy, Russian Federation, Denmark, Argentina, Netherlands, Greece, P... and more
Humanitas Mirasole SpA
KU Leuven; UMC Utrecht; University of Sheffield; Istituto Superiore di Sanità; University... and other collaborators

Active, not recruiting

Safety and Efficacy of TUDCA as add-on Treatment in Patients Affected by ALS (TUDCA-ALS)

Amyotrophic Lateral Sclerosis (ALS)

United Kingdom, Germany, France, Netherlands, Belgium, Ireland, Italy
Hoffmann-La Roche
European Commission

Completed

Safety and Efficacy of TRO19622 as add-on Therapy to Riluzole Versus Placebo in Treatment of Patients Suffering From ALS (MITOTARGET)

Amyotrophic Lateral Sclerosis

Belgium, France, Germany, Spain, United Kingdom
Janssen Research & Development, LLC

No longer available

Pre-Approval Access Single Patient Request for Talquetamab in Relapsed or Refractory Multiple Myeloma

Relapsed or Refractory Multiple Myeloma

Belgium, Iceland, Portugal, Slovenia
Amgen

Completed

Study of AMG 256 in Adult Subjects With Advanced Solid Tumors

Advanced Solid Tumors

United States, Belgium, Spain, Australia
Novartis Pharmaceuticals

Completed

Study Evaluating TCH346 and Placebo Administered Once Daily in Patients With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis

United States, Belgium, Canada, France, Germany, Italy, Netherlands, Switzerland, United Kingdom
Ono Pharmaceutical Co. Ltd

Completed

A Phase II Multi-centre, Extension Study to Investigate the Long Term Safety of ONO-2506PO in Patients Diagnosed With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis (ALS)

Belgium, France, Germany, Italy, Netherlands, Switzerland, United Kingdom
Galapagos NV

Terminated

A Clinical Study to Test Long Term Safety of GLPG1690 for Patients With Systemic Sclerosis

Systemic Sclerosis

Spain, United States, Belgium, United Kingdom, Italy
Clavis Pharma

Completed

A Study of CP-4126 in Patients With Advanced Pancreatic Cancer

Advanced Adenocarcinoma of Pancreas

Norway, Belgium
Vrije Universiteit Brussel
King's College London; University of Copenhagen; Erasmus Medical Center; University... and other collaborators

Active, not recruiting

International Study to Evaluate Two Programs of Support for Patients With Advanced Cancer and Their Families (DIAdIC)

Advanced Cancer

Belgium, Netherlands, Denmark, Ireland, United Kingdom, Italy
European Lung Cancer Working Party

Completed

Bronchoscopy Assisted by Electromagnetic Navigation (EMN) in the Diagnosis of Small Pulmonary Nodules

Pulmonary Nodule Cm

Belgium
Academisch Medisch Centrum - Universiteit van Amsterdam...

Unknown

Short-term Stenting Versus Balloon Dilatation for Dominant Strictures in Primary Sclerosing Cholangitis

Primary Sclerosing Cholangitis

Belgium, Netherlands, Norway, Sweden
Pfizer

Completed

A Phase 2 Trial of Filanesib in Relapsed/Refractory Multiple Myeloma (AfFIRM)

Advanced Multiple Myeloma

Germany, United States, Spain, United Kingdom, Belgium, Canada, France, Greece
AL-S Pharma

Recruiting

A Study to Evaluate, Safety, Tolerability, Pharmacodynamic (PD) Markers and Pharmacokinetics (PK) of AP-101 in Participants With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis

Korea, Republic of, United States, Canada, Germany, Sweden, Belgium
Astellas Pharma Inc

Completed

Clinical Study of Solifenacin Succinate in Patients With Bladder Symptoms Due to Spinal Cord Injury or Multiple Sclerosis (SONIC)

Multiple Sclerosis | Spinal Cord Diseases | Neurogenic Bladder

Australia, France, Belgium, Germany, Netherlands, Italy, Spain, United Kingdom, Hungary, Czechia, Russian Federation
Erasme University Hospital

Completed

Added Value of Cone Beam CT Guidance to Electromagnetic Navigation Bronchoscopy for the Diagnosis of Pulmonary Nodule.

Lung Cancer | Pulmonary Disease

Belgium
Novartis Pharmaceuticals

Active, not recruiting

Roll-over Study to Collect and Assess Long-term Safety of Everolimus in Patients With TSC and Refractory Seizures Who Have Completed the EXIST-3 Study [CRAD001M2304] and Who Are Benefitting From Continued Treatment

Tuberous Sclerosis Complex

United States, Spain, Belgium, Taiwan, Turkey, Australia, Korea, Republic of, Thailand, France, Hungary, United Kingdom, Italy, Japan, Canada, Russian Federation, Poland, Mexico, Colombia
Pfizer

Terminated

Study Of Bosutinib With Capecitabine In Solid Tumors And Locally Advanced Or Metastatic Breast Cancer

Advanced Breast Cancer (Parts 1 and 2) | Advanced Pancreatic Cancer (Part 1) | Advanced Colorectal Cancer (Part 1) | Advanced Cholangiocarcinoma (Part 1) | Advanced Glioblastoma Multiforme (Part 1)

United States, Spain, Hong Kong, Belgium, Australia, France
Cliniques universitaires Saint-Luc- Université...

Completed

"Overlap Syndrome and PSC: Evaluating Role of Gut Microflora and Its Identification With Antibiotics in Children"

Primary Sclerosing Cholangitis | Autoimmune Hepatitis | Overlap Syndrome

Belgium
Jean-Luc Van Laethem
Celgene Corporation

Completed

Effect on Tumor Perfusion of a Chemotherapy Combining Gemcitabine and Nab-paclitaxel (Abraxane) in Pancreatic Cancer (NEOPAX-001)

Pancreatic Adenocarcinoma Resectable | Pancreatic Adenocarcinoma Metastatic | Pancreatic Adenocarcinoma Locally Advanced

Belgium
Erasme University Hospital

Recruiting

Added Value of a Small Camera (Iriscope) in the Endoscopic Diagnosis of Peripheral Lung Nodules and Masses

Pulmonary Nodule, Solitary

Belgium
Brugmann University Hospital

Not yet recruiting

Perioperative Transfusion Strategies in Adult Congenital Heart Disease Patients Undergoing Cardiac Surgery

Cardiac Surgery | Congenital Heart Disease | Blood Transfusion | Morbidity, Multiple

Belgium
Ono Pharmaceutical Co. Ltd

Completed

Placebo Controlled Study of ONO2506PO in the Presence of Riluzole in Patients With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis (ALS)

Belgium, France, Austria, Germany, Italy, Netherlands, Switzerland, United Kingdom
Erasme University Hospital

Unknown

High-Dose Chemotherapy and Stem Cell Transplant in Treating Patients With Newly Diagnosed Stage I, Stage II, or Stage III Multiple Myeloma

Multiple Myeloma and Plasma Cell Neoplasm

Belgium, Poland
Galapagos NV

Completed

A Clinical Study to Test How Effective and Safe GLPG1690 is for Participants With Systemic Sclerosis (NOVESA)

Systemic Sclerosis

United States, Belgium, Spain, Germany, United Kingdom, Italy
Bristol-Myers Squibb

Terminated

A Study of BMS-986148 in Patients With Select Advanced Solid Tumors

Advanced Cancer

United States, Netherlands, Australia, Belgium, Canada, Italy, United Kingdom
Gesynta Pharma AB
Ergomed

Completed

A Study to Investigate Safety of GS-248 and Efficacy on Raynauds' Phenomenon in Systemic Sclerosis

Systemic Sclerosis

United Kingdom, Poland, Belgium, Netherlands
ElmediX

Recruiting

Safety Study of Whole Body Hyperthermia for Advanced Cancer (MATTERS)

Advanced Cancer | Pancreatic Cancer Metastatic

Belgium
SOTIO Biotech AG

Recruiting

A Study to Assess Safety and Efficacy of SOT201 in Patients With Advanced/Metastatic Cancer

Advanced Solid Tumor | Metastatic Solid Tumor

United States, Spain, Czechia, Belgium, France

Clinical Trials on Advanced Multiple Sclerosis in Belgium

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CROs in Denmark

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