Clinical Trials on Advanced/Metastatic Unresectable Malignant Pleural Mesothelioma

Total 826 results

Jiangsu Simcere Pharmaceutical Co., Ltd.
Shanghai Xianxiang Medical Technology Co., Ltd.; Simcere Zaiming

Recruiting

A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Preliminary Antitumor Activity of SIM0237 in Adult Participants With Advanced Solid Tumors

Locally Advanced Unresectable or Metastatic Solid Tumor

United States, China
Innovent Biologics (Suzhou) Co. Ltd.

Recruiting

A First-in-human Study of IBI343 in Subjects With Locally Advanced Unresectable or Metastatic Solid Tumors

Locally Advanced Unresectable or Metastatic Solid Tumors

Australia
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Recruiting

Study of M1774 in Combination With DNA Damage Response Inhibitor or Immune Checkpoint Inhibitor (DDRiver Solid Tumors 320)

Metastatic or Locally Advanced Unresectable Solid Tumors

United States, Canada, Spain
Takeda
Takeda Development Center Americas, Inc.

Recruiting

First-in-Human Study of TAK-280 in Participants With Unresectable Locally Advanced or Metastatic Cancer

Unresectable Locally Advanced or Metastatic Cancer

Spain, United States, Australia, Canada
Hangzhou Sumgen Biotech Co., Ltd.

Recruiting

SG1906 for CLDN18.2-Positive Solid Tumors (CSG-1906-101)

Locally Advanced Unresectable or Metastatic Solid Tumors

China
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Active, not recruiting

Tuvusertib (M1774) in Participants With Metastatic or Locally Advanced Unresectable Solid Tumors (DDRiver Solid Tumors 301)

Metastatic or Locally Advanced Unresectable Solid Tumors

United States, China, Spain, Japan, United Kingdom
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Terminated

First in Human Study of M1069 in Advanced Solid Tumors

Metastatic or Locally Advanced Unresectable Solid Tumors

United States, Canada
GlycoNex, Inc.

Terminated

Study of GNX102 in Patients With Advanced Solid Tumors

Solid Tumor | Metastatic Cancer | Advanced Cancer | Unresectable Solid Neoplasm

United States, Taiwan
University of Chicago
National Cancer Institute (NCI)

Completed

Erlotinib Hydrochloride in Treating Patients With Malignant Peritoneal Mesothelioma

Malignant Peritoneal Mesothelioma

United States
Fox Chase Cancer Center
National Cancer Institute (NCI)

Completed

Cisplatin, Interferon Alfa, Surgery, and Radiation Therapy in Treating Patients With Malignant Pleural Mesothelioma

Malignant Mesothelioma

United States
Azienda Ospedaliera Universitaria Senese

Unknown

A Clinical Study With Tremelimumab as Monotherapy in Malignant Mesothelioma

Malignant Mesothelioma

Italy
Swiss Group for Clinical Cancer Research

Completed

Combination Chemotherapy Before Surgery in Treating Patients With Mesothelioma of the Lung

Malignant Mesothelioma

Switzerland
University Medical Center Groningen

Active, not recruiting

ImmunoPET With an Anti-CD8 Imaging Agent

Metastatic Cancer | Unresectable Malignant Neoplasm

Netherlands
National Cancer Institute (NCI)

Not yet recruiting

Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)

Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm
Mayo Clinic
National Cancer Institute (NCI)

Completed

Ribociclib and Gemcitabine Hydrochloride in Treating Patients With Advanced or Metastatic Solid Tumors

Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
PrECOG, LLC.
AstraZeneca

Completed

Phase II MEDI4736 in Combination With Chemotherapy for First-Line Treatment of Unresectable Mesothelioma (PrE0505)

Mesothelioma | Pleural Mesothelioma

United States
Memorial Sloan Kettering Cancer Center
University of Pennsylvania; Dana-Farber Cancer Institute; Novartis Pharmaceuticals

Completed

Everolimus (RAD001) for the Treatment of Malignant Pleural Mesothelioma With Merlin/NF2 Loss as a Biomarker to Predict Sensitivity

Malignant Pleural Mesothelioma

United States
Mayo Clinic

Recruiting

Chemotherapy Followed by Surgery and Neoadjuvant Hemothoracic Intensity Modified Radiation Therapy (IMRT) for Patients With Malignant Pleural Mesothelioma

Mesothelioma | Solitary Fibrous Tumor of the Pleura

United States
National Cancer Institute (NCI)

Recruiting

Chemotherapy With or Without Immunotherapy for Peritoneal Mesothelioma

Peritoneal Malignant Mesothelioma

United States
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S9810: Gemcitabine Plus Cisplatin in Treating Patients With Malignant Mesothelioma of the Pleura That Cannot Be Removed by Surgery

Malignant Mesothelioma

United States
National Cancer Institute (NCI)

Terminated

Tumor Cell Vaccines With ISCOMATRIX Adjuvant and Celecoxib in Patients Undergoing Resection of Lung and Esophageal Cancers and Malignant Pleural Mesotheliomas

Esophageal Cancer | Thymoma | Lung Cancer | Thoracic Sarcomas | Mesolthelioma

United States
University Hospital, Antwerp
Kom Op Tegen Kanker; Stichting tegen Kanker

Active, not recruiting

Autologous Dendritic Cell Vaccination in Mesothelioma (MESODEC)

Malignant Pleural Mesothelioma

Belgium
Armando Santoro, MD

Completed

Study of the Combination of Tivantinib Plus Pemetrexed and Carboplatin

Nonsquamous Nonsmall Cell Neoplasm of Lung | Malignant Pleural Mesothelioma

Italy
Sellas Life Sciences Group
United States Department of Defense

Completed

WT-1 Analog Peptide Vaccine in Malignant Pleural Mesothelioma After Combined Modality Therapy

Malignant Pleural Mesothelioma

United States
Mayo Clinic

Recruiting

Staging Procedures to Diagnose Malignant Pleural Mesothelioma

Mesothelioma | Solitary Fibrous Tumor of the Pleura

United States
University of Chicago
AstraZeneca

Recruiting

Olaparib in Patients With HRD Malignant Mesothelioma

Mesothelioma | Homologous Recombination Deficiency

United States
Ankara University
Ankara Yildirim Beyazıt University; Saglik Bilimleri Universitesi; Liv Hospital...

Recruiting

Evaluation of Response by FLT PET in Mesothelioma (FLT-MM)

Chemotherapy Effect | Pleural Mesothelioma | Treatment Response

Turkey
Astellas Pharma Inc

Completed

Study of ASP1948, Targeting an Immune Modulatory Receptor, in Japanese Patients With Advanced Solid Tumors

Locally Advanced (Unresectable) or Metastatic Solid Tumor Malignancies

Japan
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Preference of Room Setting and Waiting Time in Patients With Advanced, Locally Advanced, or Metastatic Cancer and Their Caregivers Who Are Seen in the Outpatient Supportive/Palliative Care Center

Metastatic Malignant Neoplasm | Caregiver | Advanced Malignant Neoplasm | Locally Advanced Malignant Neoplasm

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI); North Central Cancer Treatment Group

Completed

Bleomycin, Doxycycline, or Talc in Treating Patients With Malignant Pleural Effusions

Metastatic Cancer
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Eastern Cooperative Oncology Group; Radiation... and other collaborators

Completed

Talc in Treating Patients With Malignant Pleural Effusion

Metastatic Cancer

United States, Canada
National Cancer Institute (NCI)

Not yet recruiting

Testing the Combination of the Anticancer Drugs Trastuzumab Deruxtecan (DS-8201a) and Azenosertib (ZN-c3) in Patients With Stomach or Other Solid Tumors

Locally Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Clinical Stage III Gastric Cancer AJCC v8 | Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Clinical Stage IV Gastric Cancer AJCC v8 | Clinical Stage... and other conditions
Sanofi
Merck Sharp & Dohme LLC

Active, not recruiting

A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With Lung Cancer or Mesothelioma (Pegathor Lung 202)

Non-small Cell Lung Cancer | Pleural Mesothelioma

Chile, Korea, Republic of, Japan, Poland, Spain, United States, Argentina, Australia, France, Italy, Taiwan
SCRI Development Innovations, LLC
Novartis Pharmaceuticals

Completed

A Study of the Hsp90 Inhibitor AUY922 Plus Capecitabine for the Treatment of Patients With Advanced Solid Tumors

Metastatic or Unresectable Solid Tumor Malignancy

United States
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Completed

Biomarkers to Detect Mesothelioma Early in Patients Exposed to Asbestos or Vermiculite

Malignant Mesothelioma | Pulmonary Complications

United States
Erasmus Medical Center

Recruiting

Intraperitoneal Paclitaxel for Patients With Primary Malignant Peritoneal Mesothelioma (INTERACT MESO)

Peritoneal Malignant Mesothelioma

Netherlands
KU Leuven

Not yet recruiting

IP3R Modulation by Cancer Genes in Mesothelioma

Malignant Mesothelioma
Swiss Group for Clinical Cancer Research

Completed

Pemetrexed Disodium and Cisplatin Followed by Surgery With or Without Radiation Therapy in Treating Patients With Malignant Pleural Mesothelioma

Malignant Mesothelioma

Switzerland, Germany
Oshadi Drug Administration

Suspended

Safety and Efficacy of Oshadi D and Oshadi R for Malignant Mesothelioma Treatment

Mesothelioma

Israel
Louisiana State University Health Sciences Center...

Unknown

Vaccine Therapy and Ganciclovir in Treating Patients With Mesothelioma

Malignant Mesothelioma

United States
Medical Research Council

Completed

Active Symptom Control With or Without Chemotherapy in Treating Patients With Malignant Pleural Mesothelioma

Malignant Mesothelioma

United Kingdom
Azienda Ospedaliera Universitaria Senese
MedImmune LLC

Unknown

The Anti-CTLA-4 Monoclonal Antibody Tremelimumab in Malignant Mesothelioma

Malignant Mesothelioma

Italy
AstraZeneca

Completed

An Open-label, Phase II Trial of ZD1839 (IRESSA) in Patients With Malignant Mesothelioma

Mesothelioma
Institute of Cancer Research, United Kingdom

Unknown

Combination Chemotherapy With or Without Surgery and Radiation Therapy in Treating Patients With Mesothelioma That Can Be Removed By Surgery

Malignant Mesothelioma

United Kingdom
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Pemetrexed Disodium/Observation in Treating Patients W/ Malignant Pleural Mesothelioma w/Out Progressive Disease After 1st Line Chemotherapy

Malignant Mesothelioma

United States
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S0722: Everolimus in Treating Patients With Pleural Malignant Mesothelioma That Cannot Be Removed By Surgery

Malignant Mesothelioma

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Gemcitabine and Epirubicin in Treating Patients With Malignant Mesothelioma

Malignant Mesothelioma

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Capecitabine in Treating Patients With Malignant Mesothelioma

Malignant Mesothelioma

United States
Cancer Trials Ireland

Completed

Bortezomib in Treating Patients With Malignant Pleural Mesothelioma

Malignant Mesothelioma

United Kingdom, Ireland, Belgium, Netherlands
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Cisplatin With or Without Pemetrexed Disodium in Treating Patients With Malignant Mesothelioma of the Pleura That Cannot be Removed by Surgery

Malignant Mesothelioma

United States

Clinical Trials on Advanced/Metastatic Unresectable Malignant Pleural Mesothelioma

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