Clinical Trials on Advanced Sarcoma

Total 8036 results

Maria Sklodowska-Curie National Research Institute...
Immutep S.A.S.

Recruiting

Pembrolizumab in Combination With Eftilagimod Alpha and Radiotherapy in Neoadjuvant Treatment of Patients With Soft Tissue Sarcoma - EFTISARC-NEO Trial (EFTISARC-NEO)

Immunotherapy | Sarcoma,Soft Tissue | Radiation Therapy | Neoadjuvant

Poland
Presage Biosciences
Northwell Health; Oregon Health and Science University; University of Washington and other collaborators

Completed

Precise Local Injection of Anti-cancer Drugs Using Presage's CIVO Device in Soft Tissue Sarcoma

Soft Tissue Sarcoma Adult

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Individualized Prehabilitation for Enhancing Recovery and Surgical Outcomes in Patients Undergoing Radiotherapy and Surgery for Soft Tissue Sarcoma

Soft Tissue Sarcoma | Stage I Soft Tissue Sarcoma of the Trunk and Extremities | Stage II Soft Tissue Sarcoma of the Trunk and Extremities | Stage III Soft Tissue Sarcoma of the Trunk and Extremities

United States
National Cancer Institute (NCI)

Active, not recruiting

Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery

Leiomyosarcoma | Fibrosarcoma | Liposarcoma | Mesenchymal Chondrosarcoma | Stage III Soft Tissue Sarcoma AJCC v7 | Stage IV Soft Tissue Sarcoma AJCC v7 | Malignant Peripheral Nerve Sheath Tumor | PEComa | Synovial Sarcoma | Epithelioid Sarcoma | Alveolar Soft Part Sarcoma | Undifferentiated High Grade Pleomorphic... and other conditions

United States, Canada, Puerto Rico
University Hospital Muenster

Completed

Study in Localized and Disseminated Ewing Sarcoma (EWING2008)

Ewing's Sarcoma

Germany
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

68Ga-FAPi-46 PET/CT Scan in Imaging Patients With Sarcoma

Sarcoma | Metastatic Sarcoma | Recurrent Sarcoma

United States
Samsung Medical Center

Recruiting

Response Based Treatment for Children With Unresectable Localized Soft Tissue Sarcoma

Unresectable Localized Soft Tissue Sarcoma

Korea, Republic of
Advenchen Laboratories, LLC

Available

Catequentinib in Patients Who Have Completed an Advenchen Study (A Compassionate Use Trial)

Gynecologic Cancer | Sarcoma,Soft Tissue
Affiliated Hospital to Academy of Military Medical...

Unknown

DCs Vaccine Combined With Cytokine-induced Killer Cells in Patients With High-risk Soft Tissue Sarcoma

High-risk Soft Tissue Sarcoma

China
St. Jude Children's Research Hospital
Tennessee Physical Therapy Association

Completed

Effects of Preoperative Physical Therapy in Patients With Lower Extremity Malignancy

Osteosarcoma | Rhabdomyosarcoma | Synovial Sarcoma | Ewing's Sarcoma | Malignant Peripheral Nerve Sheath Sarcoma | Malignant Fibrous Histiocytoma of the Bone | Chondrosarcoma of the Bone

United States
National Cancer Institute (NCI)

Completed

CCI-779 in Treating Patients With Soft Tissue Sarcoma or Gastrointestinal Stromal Tumor

Gastrointestinal Stromal Tumor | Recurrent Adult Soft Tissue Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage IV Adult Soft Tissue Sarcoma | Stage I Adult Soft Tissue Sarcoma | Stage II Adult Soft Tissue Sarcoma

United States
Italian Sarcoma Group

Completed

Protocol for the Treatment of Metastatic Ewing Sarcoma (EW-2)

Ewing's Sarcoma (ES)

Italy
Vasgene Therapeutics, Inc

Recruiting

A Study of sEphB4-HSA in Kaposi Sarcoma

Kaposi Sarcoma

United States
Pfizer

Completed

Study Of CP-751,871 In Patients With Ewing's Sarcoma Family Of Tumors

Ewing's Sarcoma Family of Tumors

Spain, France, United States, Italy, Australia, Germany, United Kingdom, Israel, Canada, Brazil, Chile
Roswell Park Cancer Institute

Recruiting

Pulmonary Suffusion in Controlling Minimal Residual Disease in Patients With Sarcoma or Colorectal Metastases

Colorectal Cancer | Metastatic Unresectable Sarcoma | Metastatic Malignant Neoplasm in the Lung | Resectable Sarcoma | Metastatic Soft Tissue Sarcoma | Metastatic Bone Sarcoma

United States
National Cancer Institute (NCI)

Recruiting

Nivolumab and Ipilimumab in Treating Patients With HIV Associated Relapsed or Refractory Classical Hodgkin Lymphoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

HIV Infection | Advanced Malignant Solid Neoplasm | Kaposi Sarcoma | Lung Carcinoma | Metastatic Malignant Solid Neoplasm | Unresectable Solid Neoplasm | Anal Carcinoma | Recurrent Classic Hodgkin Lymphoma | Refractory Classic Hodgkin Lymphoma

United States, Australia
Intensity Therapeutics, Inc.
Premier Research Group plc

Not yet recruiting

A Study to Investigate Efficacy & Safety of INT230-6 Compared to US Standard of Care in Adults With Soft Tissue Sarcomas (INVINCIBLE-3) (INVINCIBLE-3)

Sarcoma,Soft Tissue
Genor Biopharma Co., Ltd.

Recruiting

Clinical Trial in Chinese Patients of Elapsed/Metastatic/Unresectable Alveolar Soft Part Sarcoma(GB226)

Alveolar Soft Part Sarcoma

China
University of Louisville
Solving Kids' Cancer

Completed

Decitabine Followed by a Cancer Antigen Vaccine for Patients With Neuroblastoma and Sarcoma

Neuroblastoma | Osteogenic Sarcoma | Rhabdomyosarcoma | Synovial Sarcoma | Ewings Sarcoma

United States
Dana-Farber Cancer Institute
1 Million 4 Anna Foundation; Carson Sarcoma Foundation; Teaming up to Fight Childhood... and other collaborators

Completed

Palbociclib + Ganitumab In Ewing Sarcoma

Ewing Sarcoma | Ewing's Sarcoma Recurrent

United States
Parirenyatwa Hospital
University of Colorado, Denver; GlaxoSmithKline; Abbott

Completed

A Pilot Study Of the Effects of Highly Active Antiretroviral Therapy on Kaposi's Sarcoma in Zimbabwe

AIDS-related Kaposi's Sarcoma

Zimbabwe
National Cancer Institute (NCI)

Completed

Paclitaxel Compared With Doxorubicin in Treating Patients With Advanced AIDS-Related Kaposi's Sarcoma

AIDS-related Kaposi Sarcoma

United States
National Cancer Institute (NCI)

Completed

Bortezomib in Treating Patients With Relapsed or Refractory AIDS-Related Kaposi Sarcoma

HIV Infection | Recurrent Kaposi Sarcoma | AIDS-Related Kaposi Sarcoma

United States
AIDS Malignancy Consortium
National Cancer Institute (NCI); The Emmes Company, LLC

Withdrawn

Gamma Secretase Inhibitor PF-03084014 in Treating Patients With AIDS-Associated Kaposi Sarcoma

HIV Infection | AIDS-related Kaposi Sarcoma | Recurrent Kaposi Sarcoma
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of Arkansas; The Emmes Company, LLC; Vasgene Therapeutics, Inc

Recruiting

sEphB4-HSA in Treating Patients With Kaposi Sarcoma

Skin Kaposi Sarcoma

United States
Alona Zer
Bristol-Myers Squibb

Unknown

Nivolumab and Ipilimumab in Classical Kaposi Sarcoma (CKS)

Classic Kaposi Sarcoma

Israel
Massachusetts General Hospital

Completed

Olaparib in Adults With Recurrent/Metastatic Ewing's Sarcoma

Ewing's Sarcoma

United States
Memorial Sloan Kettering Cancer Center

Recruiting

Irinotecan and Temozolomide in Combination With Existing High Dose Alkylator Based Chemotherapy for Treatment of Patients With Newly Diagnosed Ewing Sarcoma

Newly Diagnosed Ewing Sarcoma

United States
Sarcoma Alliance for Research through Collaboration
Merck Sharp & Dohme LLC; Stand Up To Cancer

Active, not recruiting

A Randomized Trial of Pembrolizumab & Radiotherapy Versus Radiotherapy in High-Risk Soft Tissue Sarcoma of the Extremity (SU2C-SARC032)

Soft Tissue Sarcoma of the Extremity

United States, Australia, Canada, Italy
Institut Claudius Regaud

Recruiting

Multimodal Immune Characterization of RAre Soft Tissue Sarcoma - MIRAS Project From SARRA (SARcome RAre) Project of the French Sarcoma Group (MIRAS)

Soft Tissue Sarcoma | Perivascular Epithelioid Cell Neoplasms | Epithelioid Sarcoma | Alveolar Soft Part Sarcoma | Desmoplastic Small Round Cell Tumor | Clear Cell Sarcoma | Sclerosing Epithelioid Fibrosarcoma | Low Grade Fibromyxoid Sarcoma | Malignant Solitary Fibrous Tumors | Epithelioid Hemangioendothelioma

France
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Recruiting

Efficacy and Safety of TQB2450 Injection Combined With Chemotherapy ± Anlotinib Hydrochloride Capsules for Advanced Endometrial Cancer or Sarcoma of Uterus.

Advanced Endometrial Cancer | Sarcoma of Uterus

China
National Cancer Institute (NCI)

Active, not recruiting

Phase II Study of Cediranib (AZD2171) in Patients With Alveolar Soft Part Sarcoma

Sarcoma, Alveolar Soft Part

United States
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Terminated

A Study of Mitoxantrone Hydrochloride Liposome Injection in Subjects With Advanced Bone and Soft Tissue Sarcoma

Unresectable or Metastatic Bone and Soft Tissue Sarcoma

China
Children's Hospital of Philadelphia

Recruiting

Synovial Sarcoma Registry / Biospecimen Repository

Synovial Sarcoma

United States
Fujun Zhang

Recruiting

Brachytherapy (Iodine-125 Seeds) and Fluzoparib Combination Therapy for Advanced Unresectable Soft Tissue Sarcoma (RAFAS-001)

Sarcoma,Soft Tissue | Brachytherapy | Poly(ADP-ribose) Polymerase Inhibitors

China
Universitaire Ziekenhuizen KU Leuven

Recruiting

Assessment of the Functional Outcome and Quality of Life in Sarcoma Patients (QOLSarcoma)

Soft Tissue Sarcoma | Bone Sarcoma

Belgium
Jonsson Comprehensive Cancer Center
Sarcoma Alliance for Research through Collaboration; Radiological Society of... and other collaborators

Recruiting

Phase II Study of 5-Day Hypofractionated Preoperative Radiation Therapy for Soft Tissue Sarcomas: Expansion Cohort

Recurrent Adult Soft Tissue Sarcoma

United States
Takara Bio Inc.

Completed

Study of TBI-1301 (NY-ESO-1 T Cell Receptor Gene Transduced Autologous T Lymphocytes) in Patients With Synovial Sarcoma

Synovial Sarcoma

Japan
Washington University School of Medicine

Terminated

DHEA in Synovial Sarcoma Patients

Synovial Sarcoma | Sarcoma, Synovial

United States
Medical College of Wisconsin

Completed

(SBRT) and (ART) for Pulmonary Metastases From Soft Tissue Sarcomas

Stage IV Adult Soft Tissue Sarcoma | Sarcoma,Soft Tissue

United States
National Cancer Institute (NCI)

Completed

A Pilot Study of Autologous T-Cell Transplantation With Vaccine Driven Expansion of Anti-Tumor Effectors After Cytoreductive Therapy in Metastatic Pediatric Sarcomas

Rhabdomyosarcoma | Ewing's Sarcoma

United States
AIDS Malignancy Consortium
National Cancer Institute (NCI)

Not yet recruiting

A Study of Propranolol to Treat Kaposi Sarcoma

Kaposi Sarcoma

Uganda, Argentina, Kenya, Mexico, Malawi, Zimbabwe, Brazil, South Africa
Massachusetts General Hospital
National Institutes of Health (NIH); Infectious Diseases Institute, Uganda

Completed

Smartphone Confocal Microscopy for Diagnosing Kaposi's Sarcoma

Kaposi Sarcoma

Uganda
Mayo Clinic

Recruiting

Comparing Carbon Ion Therapy, Surgery, and Proton Therapy for Management of Pelvic Sarcomas Involving the Bone

Ewing Sarcoma of Bone | Chondrosarcoma | Chordoma | Bone Sarcoma | Pelvic Rhabdomyosarcoma

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Combination of Belinostat and SGI-110 (Guadecitabine) or ASTX727 for the Treatment of Unresectable and Metastatic Conventional Chondrosarcoma

Metastatic Primary Central Chondrosarcoma | Unresectable Primary Central Chondrosarcoma | Locally Advanced Unresectable Primary Central Chondrosarcoma

United States
OHSU Knight Cancer Institute
Bayer; Oregon Health and Science University

Completed

Sorafenib Tosylate, Combination Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With High-Risk Stage IIB-IV Soft Tissue Sarcoma

Pleomorphic Rhabdomyosarcoma | Stage III Adult Soft Tissue Sarcoma AJCC v7 | Stage IV Adult Soft Tissue Sarcoma AJCC v7 | Stage IIB Adult Soft Tissue Sarcoma AJCC v7

United States
China Association of Osteosarcoma Chemotherapy

Unknown

A Clinical Trial on Efficacy and Safety for Lobaplatin and Gemcitabine in Combination With Docetaxel in the Second-line Treatments on Advanced Osteosarcoma

Lobaplatin and Gemcitabine in Combination, Second-line Treatments on Advanced Osteosarcoma
AIDS Malignancy Consortium
National Cancer Institute (NCI)

Not yet recruiting

Paclitaxel and Pegylated Liposomal Doxorubicin for Treatment of HIV-related Kaposi Sarcoma

Kaposi Sarcoma | HIV-1-infection | AIDS-related Kaposi Sarcoma
Yonsei University

Recruiting

Pemetrexed, Cisplatin With Soft Tissue Sarcoma (ALBATROSS)

Sarcoma,Soft Tissue

Korea, Republic of
Liaoning Tumor Hospital & Institute
China-Japan Friendship Hospital; First Hospital of China Medical University; Second... and other collaborators

Unknown

Anlotinib Hydrochloride Combined With Epirubicin and Ifosfamide for Soft Tissue Sarcoma Patients (ALTER-S005)

Sarcoma, Soft Tissue

China

Clinical Trials on Advanced Sarcoma

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Drug Interventions

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CROs in Romania

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