- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT05910307
Synovial Sarcoma Registry / Biospecimen Repository
Synovial Sarcoma Registry and Biospecimen Repository
The purpose of this study is to collect and store data and samples for future research to attempt to improve outcomes for patients with synovial sarcoma. The future research will involve various types of genetic testing.
Participants will be asked to allow access to medical records and leftover tumor tissue and may be asked to give a blood or saliva sample. Participants will also be asked to completed questionnaires about their medical history and may be contacted every 6 to 12 months for updates for up to 10 years.
Study Overview
Status
Conditions
Detailed Description
This study will enroll patients with a diagnosis of Synovial Sarcoma.
Following consent, demographic, clinical, treatment and outcome data will be collected from an interview and/or online survey. This will include a request for contact information for the subject's treating hospitals/physicians and a release of records request to obtain medical records.
At approximately 6-12 month intervals for up to 10 years after initial diagnosis and/or relapse, subjects and/or their treating hospitals may be contacted to provide updates on treatment and outcomes.
Tumor samples may be collected from residual material obtained during clinically indicated procedures occurring before or after consent to this study. No additional material will be collected or procedures performed solely for the purpose of this study.
Blood may be collected at the participant's local institution at the time of a clinically indicated blood draw and/or saliva or a buccal swab may be collected as a germline sample and for analysis of circulating free DNA (cfDNA) and/or circulating tumor cells (CTCs).
Genetic testing may be performed on tumor and germline samples submitted by subjects. Results will only be returned if deemed clinically significant.
Study Type
Enrollment (Estimated)
Contacts and Locations
Study Contact
- Name: James Robinson
- Phone Number: 215-590-2053
- Email: robinsonj9@chop.edu
Study Contact Backup
- Name: Lauren Gutstein
- Phone Number: 267-425-2029
- Email: gutsteinl1@chop.edu
Study Locations
-
-
Pennsylvania
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Philadelphia, Pennsylvania, United States, 19104
- Recruiting
- Children's Hospital of Philadelphia
-
Contact:
- Lauren Gutstein
- Phone Number: 267-425-2029
- Email: gutsteinl1@chop.edu
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
- Child
- Adult
- Older Adult
Accepts Healthy Volunteers
Sampling Method
Study Population
Description
Inclusion Criteria:
- Males or females of any age
- Reported diagnosis of synovial sarcoma
- Informed consent from subject (aged ≥18 years) or parent/guardian
Exclusion Criteria:
- Individuals with sarcomas that do not fit the definition of those considered for this registry
- Individuals who are unwilling to participate
- Individuals who are unwilling or unable to provide written consent
Study Plan
How is the study designed?
Design Details
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Number of patients with synovial sarcoma
Time Frame: Up to 10 years
|
Number of patients with synovial sarcoma
|
Up to 10 years
|
Collaborators and Investigators
Investigators
- Principal Investigator: Theodore Laetsch, MD, Children's Hospital of Philadelphia
Publications and helpful links
Helpful Links
Study record dates
Study Major Dates
Study Start (Actual)
Primary Completion (Estimated)
Study Completion (Estimated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- 23-021012
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
IPD Plan Description
IPD Sharing Time Frame
IPD Sharing Access Criteria
IPD Sharing Supporting Information Type
- STUDY_PROTOCOL
- ICF
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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