Clinical Trials on Age-Related Cognitive Decline

Total 2072 results

University Hospital, Angers
University of Angers, Angers

Unknown

Neuropsychological Assessment of Children and Adolescents With Turner Syndrome (ENEAST)

Isolated Growth Hormone Deficiency | Turner Syndrome | Pediatrics | Social Cognition | Cognitive Functions
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Terminated

Ph I Study of Lithium During Whole Brain Radiotherapy For Patients With Brain Metastases

Solid Tumor | Brain and Central Nervous System Tumors | Neurotoxicity | Cognitive/Functional Effects

United States
Galina Velikova
The Leeds Teaching Hospitals NHS Trust; European Organisation for Research...

Completed

Long Term Implications of Rare Brain Tumours'

Quality of Life | Cognitive Impairment | Health-related Quality of Life | Long-term Effects of Cancer Treatment | WHO Grade II Oligodendroglial Tumor | WHO Grade III Oligodendroglial Tumor

Netherlands, United Kingdom
University of California, San Francisco
National Cancer Institute (NCI)

Completed

Effects of Chemotherapy on the Brain in Women With Newly Diagnosed Early-Stage Breast Cancer

Breast Cancer | Fatigue | Neurotoxicity | Cognitive/Functional Effects | Psychosocial Effects of Cancer and Its Treatment | Long-term Effects Secondary to Cancer Therapy in Adults | Chemotherapeutic Agent Toxicity

United States
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Withdrawn

BBBD Followed By Methotrexate and Carboplatin With or Without Trastuzumab in Treating Women With Breast Cancer That Has Spread to the Brain

Breast Cancer | Brain and Central Nervous System Tumors | Cognitive/Functional Effects | Psychosocial Effects of Cancer and Its Treatment | Drug/Agent Toxicity by Tissue/Organ
Assiut University

Not yet recruiting

Fetal Clavicular Measurement to Predict Fetal Macrosomia

Shoulder Dystocia | Macrosomia, Fetal | Large for Gestational Age
Fondation Ophtalmologique Adolphe de Rothschild

Completed

Assessment of Age-related Hearing Loss in HIV-1 Patients (HELO)

HIV Seropositivity

France
Duke University
University of Edinburgh in Scotland; Tan Tock Seng Hospital in Singapore; Queens...

Recruiting

Retinal Imaging in Neurodegenerative Disease

Multiple Sclerosis | Parkinson's Disease | Traumatic Brain Injury | Down Syndrome | Mild Cognitive Impairment | Frontotemporal Dementia | Huntington Disease | Amyotrophic Lateral Sclerosis (ALS) | Alzheimer's Disease | Concussion | Post-Traumatic Stress Disorder | Neuro-Degenerative Disease | Lewy Body Dementia | Normal... and other conditions

United States
Queen Mary University of London

Completed

ESTEEM - Effect of Simple, Targeted Diet in Pregnant Women With Metabolic Risk Factors on Pregnancy Outcomes (ESTEEM)

Obesity | Insulin Resistance | Gestational Diabetes | High Blood Pressure | Pre-eclampsia | Stillbirth | Small for Gestational Age | Raised Lipids

United Kingdom
Columbia University
National Institute on Minority Health and Health Disparities (NIMHD); National...

Active, not recruiting

Northern Manhattan Study of Metabolism and Mind (NOMEM)

Diabetes | Metabolic Syndrome | Depressive Symptoms | Pre-diabetes | Cognition - Other

United States
Washington University School of Medicine

Recruiting

Amygdala Memory Enhancement

Brain Diseases | Epilepsy | Cognitive Impairment | Traumatic Brain Injury | Post Traumatic Stress Disorder | Memory Disorders

United States
University of South Florida
National Cancer Institute (NCI)

Completed

Modafinil in Treating Children With Memory and Attention Problems Caused by Cancer Treatment for a Brain Tumor

Fatigue | Brain and Central Nervous System Tumors | Neurotoxicity | Cognitive/Functional Effects | Psychosocial Effects of Cancer and Its Treatment

United States
University of California, Los Angeles
United States Department of Defense

Not yet recruiting

Personalized Brain Stimulation to Treat Chronic Concussive Symptoms

Depression | Anxiety | Dizziness | Headache | Post-Concussion Syndrome | Cognitive Symptom | Post-traumatic Stress Disorder | Dysautonomia | Mild Traumatic Brain Injury | Head Injury | Concussion, Brain | Irritability; Syndrome

United States
Mount Sinai Hospital, Canada
Cambridge University Hospitals NHS Foundation Trust; University of Cambridge; Jaeb Center for Health Research and other collaborators

Completed

Continuous Glucose Monitoring in Women With Type 1 Diabetes in Pregnancy Trial (CONCEPTT)

Type 1 Diabetics Who Are Pregnant or Planning Pregnancy

Canada, United Kingdom, Spain, United States, Ireland, Italy
Scripps Translational Science Institute
Cue Health

Recruiting

ImmunoCARE: Rapid, Accurate COVID Testing to Reduce Hospitalization of Immunocompromised Individuals

HIV Infections | Lymphoma | Leukemia | Cancer | Multiple Myeloma | Immunosuppression | Immunodeficiency | Transplant | Graft Versus Host Disease | Age-Related Immunodeficiency

United States
Centre Hospitalier Régional Metz-Thionville

Recruiting

Long-term Quality of Life and Prognostic Factors in Severe COVID-19 Patients and Their Relatives (QUALICOVID)

COVID-19 | Quality of Life | Cognitive Impairment | Posttraumatic Stress Disorder | Social Behavior

France
First Affiliated Hospital Xi'an Jiaotong University
Second Affiliated Hospital of Wenzhou Medical University

Completed

Imaging Biomarkers of Mild Traumatic Brain Injury: a Longitudinal Cohort Study

Posttraumatic Stress Disorder | Mild Traumatic Brain Injury | Cognitive Impairments | Affective and Somatic Complaints

China
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Donepezil in Treating Young Patients With Primary Brain Tumors Previously Treated With Radiation Therapy to the Brain

Brain and Central Nervous System Tumors | Neurotoxicity | Radiation Toxicity | Cognitive/Functional Effects | Long-term Effects Secondary to Cancer Therapy in Children | Psychosocial Effects of Cancer and Its Treatment

United States
King Abdullah International Medical Research Center

Completed

Effect of Tahneek on Hypoglycemia in Newborn Infants (THIN)

Intrauterine Growth Restriction | Premature Infant | Infant, Small for Gestational Age | Neonatal Hypoglycemia | Macrosomia, Fetal | Neonatal; Hypoglycemia, Diabetes, Maternal

Saudi Arabia
University of Colorado, Denver

Completed

Fit After Baby: Increasing Postpartum Weight Loss in Women at Increased Risk for Cardiometabolic Disease (FAB)

Cardiovascular Diseases | Diabetes | Preterm Birth | Overweight and Obesity | Preeclampsia | Gestational Diabetes | Small for Gestational Age at Delivery | Gestational Hypertension

United States
Turku University Hospital
University of Turku

Completed

Nutrition and Pregnancy Intervention Study

Liver Diseases | Obesity | Pregnancy | Neurodevelopmental Disorders | Type2 Diabetes | Adiposity | Cardiovascular Risk Factor | Gestational Diabetes Mellitus | Eating Behavior | Cognitive Developmental Disorders

Finland
Assistance Publique - Hôpitaux de Paris

Recruiting

Drug Reactions Sampling (COLLECTIONTOXIDERMIES)

Erythema Multiforme | Stevens-Johnson Syndrome | Lyell Syndrome | Drug Reactions | AGEP | DRESS | Bullous Dermatosis Caused by Drug Treatment (Disorder) | Maculopapular Exanthem

France
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Natural History of Brain Function, Quality of Life, and Seizure Control in Patients With Brain Tumor Who Have Undergone Surgery

Neurotoxicity | Cognitive/Functional Effects | Psychosocial Effects of Cancer and Its Treatment | Adult Diffuse Astrocytoma | Adult Mixed Glioma | Adult Oligodendroglioma | Seizure

United States, Canada
Children's Cancer and Leukaemia Group

Active, not recruiting

Observing Young Patients With Ependymoma Undergoing Standard Combination Chemotherapy

Brain and Central Nervous System Tumors | Ototoxicity | Cognitive/Functional Effects | Long-term Effects Secondary to Cancer Therapy in Children

United Kingdom
Yonsei University

Completed

Does Low Dose of Dexamethasone Enhance Analgesic Quality of Caudal Analgesia in Children Undergoing Orchiopexy?

Patients With Cryptorchism Who Are Planning to Undergo Orchiopexy

Korea, Republic of
Sun Yat-sen University

Unknown

Biomarkers of Common Eye Diseases

Uveitis | Diabetic Retinopathy | Age-related Macular Degeneration | Polypoidal Choroidal Vasculopathy | Behçet Disease | VKH Syndrome

China
Brigham and Women's Hospital

Completed

The Role of Mineralocorticoid Receptors in Vascular Function

Apparent Mineralocorticoid Excess (AME)

United States
Dong-A ST Co., Ltd.

Recruiting

Long-term Safety and Effectiveness of Growtropin®-II Treatment in Children With Short Stature

Growth Hormone Deficiency | Turner Syndrome | Small for Gestational Age | Idiopathic Short Stature

Korea, Republic of
Baylor University

Completed

Prophylactic Dextrose Gel for Newborns at High-risk for Hypoglycemia

Hypoglycemia | Premature Birth of Newborn | Intrauterine Growth Restriction | Fetal Macrosomia | Infant, Small for Gestational Age | Neonatal Hypoglycemia | Complication of Prematurity

United States
Merck KGaA, Darmstadt, Germany

Completed

Evaluation of Convenience and Compliance of the Easypod™ Electronic Self-injector

Growth Hormone Deficiency | Chronic Renal Failure | Turner Syndrome | Small for Gestational Age
The University of Texas Health Science Center at...

Completed

Metabolism of Low Carbohydrate and Ketogenic Diet

Diabetic Kidney Disease | Weight Loss | Cognitive Function | Type2 Diabetes | Diabetic Control

United States
National Medical Research Center for Rehabilitation...
Pirogov Russian National Research Medical University; DNKOM LLC; The Orenburg...

Recruiting

Study of Efficacy and Safety of the Plasmapheresis Method With Albumin Compensation Compared With the Plasmapheresis Method Without Albumin Compensation for Aging Biomarkers Correction in Men and Women Aged 40 to 55 Years Old

Cardiovascular Diseases | Nervous System Diseases | Urologic Diseases | Diabetes | Neuromuscular Diseases | Hypercholesterolemia | Gout | Hyperbilirubinemia | Hyper IgE Syndrome | Hyper-LDL-cholesterolemia | Hyper Beta Lipoproteinemia | Hyper Eosinophilic Syndrome

Russian Federation
Xiamen Amoytop Biotech Co., Ltd.
Tongji Hospital

Completed

A Trial of YPEG-rhGH in Children With Short Stature

Turner Syndrome | Small for Gestational Age | Idiopathic Short Stature

China
Centre Hospitalier Universitaire de Besancon
Novartis Pharmaceuticals; National Cancer Institute, France; National Research... and other collaborators

Terminated

Multicenter Prospective Cohort of Informal Caregivers in Burgundy and Franche-Comté (ICE)

Breast Cancer | Ischemic Stroke | Parkinson Disease | Age-related Macular Degeneration | Colorectal Cancer | Alzheimer Disease | Prostate Cancer | Hemorrhagic Stroke | Cardiac Disease

France
Royal Marsden NHS Foundation Trust

Unknown

Feasibility of Frailty Assessment and Implementation of Interventions in Women Over 70 With Epithelial Ovarian Cancer (FAIR-O)

Quality of Life | Ovarian Cancer | Chemotherapy | Tolerance | Aged
National Institute of Mental Health (NIMH)

Terminated

PET Evaluation of Brain Peripheral Benzodiazepine Receptors Using [11C]PBR28 in HIV-Seropositive Patients With (MCMD)

HIV Infections | Healthy | AIDS Dementia Complex | AIDS-Related Dementia Complex | HIV-Associated Cognitive Motor Complex | HIV-Dementia | AIDS Encephalopathy

United States
LG Life Sciences

Completed

Evaluation of the Ease of Use, Preference, and Safety of EutropinPen Inj.

Growth Hormone Deficiency | Chronic Renal Failure | Turner Syndrome | Infant, Small for Gestational Age | Short Stature, Idiopathic

Korea, Republic of
LG Chem

Recruiting

Long-term Safety and Effectiveness of Growth Hormone With GHD, TS, CRF, SGA , ISS and PWS in Children (LGS)

Growth Hormone Deficiency | Chronic Renal Failure | Turner Syndrome | Small for Gestational Age | Idiopathic Short Stature

Korea, Republic of
Novo Nordisk A/S

Completed

Safety and Efficacy of Long-term Somatropin Treatment in Children (GrowthWIN II)

Turner Syndrome | Growth Hormone Disorder | Growth Hormone Deficiency in Children | Genetic Disorder | Foetal Growth Problem | Small for Gestational Age | Growth Disorder | Idiopathic Short Stature

Germany
Luye Pharma Group Ltd.

Recruiting

Safety, Tolerability and Pharmacokinetic of Multiple-ascending Doses of LPM3770164 in Healthy Subjects

Tardive Dyskinesia | Huntington Disease

China
Luye Pharma Group Ltd.

Completed

A Dose-escalation Study to Evaluate the Safety, Tolerability and Pharmacokinetic of LPM3770164 in Healthy Subjects

Tardive Dyskinesia | Huntington Disease

China
Amsterdam UMC, location VUmc

Completed

GH and Cardiovascular Risk Factors

Cardiovascular Diseases | Physical Activity | Metabolic Syndrome | Growth Hormone Deficiency | Cognition

Netherlands
Novo Nordisk A/S

Completed

Norditropin NordiFlex® Device Compared to the Device Previously Used by Patients or Parents

Chronic Kidney Disease | Turner Syndrome | Chronic Renal Insufficiency | Growth Hormone Disorder | Growth Hormone Deficiency in Children | Genetic Disorder | Delivery Systems | Foetal Growth Problem | Small for Gestational Age

France
Novo Nordisk A/S

Completed

Usability and Tolerability of the Norditropin NordiFlex® Injection Device in Children Never Previously Treated With Growth Hormone

Chronic Kidney Disease | Turner Syndrome | Chronic Renal Insufficiency | Growth Hormone Disorder | Growth Hormone Deficiency in Children | Genetic Disorder | Delivery Systems | Foetal Growth Problem | Small for Gestational Age

France
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Brain Function in Young Patients Receiving Methotrexate for Acute Lymphoblastic Leukemia

Untreated Childhood Acute Lymphoblastic Leukemia | Childhood T Acute Lymphoblastic Leukemia | Neurotoxicity Syndrome | Childhood B Acute Lymphoblastic Leukemia | Cognitive Side Effects of Cancer Therapy | Psychological Impact of Cancer | Long-Term Effects Secondary to Cancer Therapy in Children

United States, Canada, Australia, New Zealand
Gdansk University of Physical Education and Sport
Pomeranian Medical University Szczecin; Medical University of Gdansk; University...

Recruiting

HIIT vs MICT During Pregnancy and Health and Birth Outcomes in Mothers and Children (HIIT MAMA)

Depression | Back Pain | Urinary Incontinence | Pregnancy | Anxiety | Body Composition | Cognitive Function | Pelvic Floor Disorders | Noncommunicable Diseases | Physical Fitness | Metabolism | Postpartum | Health Status | Pregnancy Induced Hypertension | Pain Threshold | Childbirth | Diabetes Mellitus, Gestational | Biomecha...

Poland
Universitaire Ziekenhuizen KU Leuven
University Hospital, Ghent; Gasthuis Zusters Antwerpen

Recruiting

Neurocognition After Radiotherapy in CNS- and Skull-base Tumors (NARCiS)

Glioma | Pituitary Adenoma | Brain Tumor | Magnetic Resonance Imaging | Meningioma | Cognition

Belgium
Okuvision GmbH

Completed

Transcorneal Electrical Stimulation Therapy for Retinal Disease

Primary Open Angle Glaucoma | Retinal Vein Occlusion | Retinitis Pigmentosa | Retinal Artery Occlusion | Dry Age Related Macular Degeneration | Hereditary Macular Degeneration | Macula Off | Treated Retina Detachment | Non-Arthritic-Anterior-Ischemic Optic-Neuropathy | Hereditary Autosomal Dominant Optic... and other conditions
AbbVie

No longer available

Expanded Access to Veliparib

High Grade Serous Ovarian Cancer | Solid Tumors With Documented BRCA, BARD, or PALB or Other Acceptable DNA Mutations or Anomalies That Are Scientifically Sound | Triple Negative Breast Cancer (TNBC) | Patients Requiring Veliparib Suspension Formulation
QuantalX Neuroscience

Completed

DELPHI in Subjects at Risk for Stroke and Dementia

Smoking | Stroke | Hypertension | Sleep Disorder | Cognitive Impairment | Atrial Fibrillation | Transient Ischemic Attack | Dyslipidemias | Familial Alzheimer Disease | Diabete Mellitus | Overweight and Obesity | Cardiac Disease

United States, Israel

Clinical Trials on Age-Related Cognitive Decline

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CROs in Ecuador

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