Clinical Trials on Alzheimer Disease 2 Due to Apoe4 Isoform in United States

Total 254 results

University of Kansas Medical Center
National Institute on Aging (NIA)

Completed

Dementia Risk and Dynamic Response to Exercise (DYNAMIC)

Healthy Aging | Alzheimer Disease 2 Due to Apoe4 Isoform

United States
Yu-Hsiang Wu
Vanderbilt University Medical Center; National Institute on Deafness and Other...

Recruiting

Hearing Aid and Individuals With Cognitive Disorders

Alzheimer Disease 2 Due to Apoe4 Isoform | Presbycusis, Bilateral

United States
Centers for Medicare and Medicaid Services/ Coverage...

Recruiting

Medicare Anti-Aβ mAb Coverage With Evidence Development (CED) Study

Mild Alzheimer's Disease | Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease

United States
APRINOIA Therapeutics, LLC

Active, not recruiting

Evaluation of [18F]APN-1607 PET Uptake in Alzheimer's Disease Patients Compared With Healthy Subjects

Healthy Volunteers | Alzheimer's Disease | Mild Cognitive Impairment Due to Alzheimer's Disease

United States
South London and Maudsley NHS Foundation Trust

Enrolling by invitation

UK Based Remote Brain Health Clinic (BHC) for Patients With Mild Cognitive Impairment (MCI) (BHC)

Mild Cognitive Impairment | Mild Cognitive Impairment Due to Alzheimer's Disease

United Kingdom
Medical College of Wisconsin
National Institute on Aging (NIA)

Completed

Network-Level Mechanisms for Preclinical Alzheimer's Disease Development

APOE 4

United States
Takeda
Zinfandel Pharmaceuticals Inc.

Terminated

Biomarker Qualification for Risk of Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease (AD) and Safety and Efficacy Evaluation of Pioglitazone in Delaying Its Onset (TOMMORROW)

Mild Cognitive Impairment Due to Alzheimer's Disease

United States, Germany, Switzerland, United Kingdom, Australia
Biogen

Recruiting

A Study to Learn About the Safety of BIIB080 and Whether it Can Improve Symptoms of Participants With Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild AD Dementia Between 50 to 80 Years of Age (CELIA)

Mild Cognitive Impairment Due to Alzheimer's Disease | Alzheimer's Disease Dementia

Belgium, United States, Australia, Italy, Spain, Denmark, United Kingdom, Czechia, France, Poland, Germany, Canada, Japan, Finland, Switzerland, Netherlands, Sweden
University of Texas Southwestern Medical Center

Completed

Clinical Trial of Lamotrigine to Reverse Cognitive Impairment in Chronic Corticosteroid-Treated Patients

Memory Impairment Due to Corticosteroid Use | Hypomania Due to Corticosteroid Use | Hippocampal Atrophy Due to Corticosteroid

United States
Orthocare Innovations, LLC
National Institute on Disability, Independent Living, and Rehabilitation...

Recruiting

mGain - sEMG-based Gamified Therapy for Improved Upper Limb Rehabilitation

Stroke | Upper Limb Amputation | Upper Limb Weakness Due to Central Neurologic Injury | Upper Limb Weakness Due to Peripheral Neurologic Injury | Upper Limb Weakness Due to Nerve Reconstruction | Upper Limb Weakness Due to Tendon Transfer Surgery

United States
Takeda

Terminated

AD-4833/TOMM40_303 Extension Study of the Safety and Efficacy of Pioglitazone to Slow Cognitive Decline in Participants With Mild Cognitive Impairment Due to Alzheimer Disease

Mild Cognitive Impairment Due to Alzheimer's Disease

United States, Australia, United Kingdom, Switzerland
Johns Hopkins University

Completed

CGM Use in Children With Type 2 Diabetes (IMPaCT2)

Type 2 Diabetes | Hyperglycemia Due to Type 2 Diabetes Mellitus

United States
Stanford University
Alkahest, Inc.

Completed

The PLasma for Alzheimer SymptoM Amelioration (PLASMA) Study (PLASMA)

Alzheimer's Disease | Mild-To-Moderate Alzheimer's Disease

United States
University of Arizona
National Cancer Institute (NCI)

Recruiting

SUV PDL1/PD1 in Sun Damaged & Sun Protected Human Skin of Participants

Other Skin Changes Due to Chronic Exposure to Nonionizing Radiation

United States
GemVax & Kael

Active, not recruiting

GV1001 Subcutaneous(SC) for the Treatment of Mild to Moderate Alzheimer's Disease (AD)

Mild to Moderate Alzheimer's Disease

Spain, United States, Netherlands, Poland
Mayo Clinic

Terminated

Prophylactic Ethanol Lock Therapy (ELT) in Patients on Home Parenteral Nutrition (ELT)

Catheter-related Bloodstream Infection (CRBSI) Nos | Bloodstream Infection Due to Central Venous Catheter | Bloodstream Infection Due to Hickman Catheter

United States
Russell Swerdlow
Ausio Pharmaceuticals, LLC

Completed

S-Equol in Alzheimer's Disease 2 Trial (SEAD2)

Alzheimer Disease

United States
Pain Concern
The Thistle Foundation; Health and Social Care Alliance Scotland (the ALLIANCE) and other collaborators

Completed

Supporting Self-management of Chronic Pain

Chronic Pain | Chronic Pain Syndrome | Chronic Pain, Widespread | Chronic Pain Due to Trauma | Chronic Pain Due to Malignancy (Finding) | Chronic Pain Due to Injury | Chronic Pain Post-Procedural | Chronic Pain Hip

United Kingdom
Oryzon Genomics S.A.
Alzheimer's Drug Discovery Foundation

Completed

Testing the Safety and Preliminary Efficacy of the New Drug ORY-2001 in Mild to Moderate Alzheimer's Disease (ETHERAL-US)

Mild to Moderate Alzheimer's Disease

United States
Alkahest, Inc.

Completed

A Randomized Study to Assess the Safety of GRF6019 Infusions in Subjects With Mild to Moderate Alzheimer's Disease

Alzheimer Disease | Mild to Moderate Alzheimer Disease

United States
Research Foundation for Mental Hygiene, Inc.

Completed

HealthCall:Brief Intervention to Reduce Non-injecting Drug Use in HIV Primary Care Clinics

Mental and Behavioral Disorders Due to Harmful Drug Use

United States
DeviceFarm, Inc.
Symbio, LLC; Center for Dermatology Clinical Research, Inc.

Completed

Early Feasibility Study to Evaluate the Efficacy and Safety of the RenewalNail™ Plasma Treatment System in Patients With Mild to Moderate Onychomycosis (Fungal Nail)

Onychomycosis Due to Trichophyton Rubrum | Onychomycosis Due to Trichophyton Mentagrophytes

United States
The University of Texas Health Science Center,...
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Stem Cell Injection in Cancer Survivors (SENECA)

Cardiomyopathy Due to Anthracyclines

United States
AstraZeneca

Completed

A Two-part Multiple Dose Study to Assess the Safety and Effects of AZD3293 in Healthy Elderly and Alzheimer's Patients

Healthy Elderly Volunteers | Mild-to-moderate Alzheimer's Disease Patients

United States
Medivation, Inc.
Pfizer

Terminated

A Safety and Efficacy Study Evaluating Dimebon (Latrepirdine) in Patients With Moderate to Severe Alzheimer's Disease (CONTACT)

Moderate to Severe Alzheimer

Chile, United Kingdom
Ekso Bionics

Completed

Exoskeleton Treatment of Deconditioning Due to Limited Ambulation Caused by Illness or Injury

Debility Due to Disease

United States
The University of Texas Health Science Center,...
Otto Bock Healthcare Products GmbH

Completed

Clinical Algorithm for Post-Stroke Gait Training With C-Brace

Hemiparesis Due to Stroke | Hemiplegia Due to Stroke

United States
Cognito Therapeutics, Inc.

Recruiting

A Pivotal Study of Sensory Stimulation in Alzheimer's Disease (Hope Study, CA-0011) (Hope)

Cognitive Impairment | Dementia | Alzheimer Disease | Mild Cognitive Impairment | Cognitive Decline | Alzheimer Disease, Early Onset | Alzheimer Disease, Late Onset | MCI | Dementia Alzheimers | Mild Dementia | Dementia of Alzheimer Type | Cognitive Impairment, Mild | Alzheimer Disease 1 | Dementia, Mild | Alzheimer... and other conditions

United States
King's College London

Unknown

Donepezil and Memantine in Moderate to Severe Alzheimer's Disease (DOMINO-AD)

Moderate to Severe Alzheimer's Disease

United Kingdom
ProgenaBiome

Recruiting

A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Alzheimer's Disease

Alzheimer Disease | Alzheimer Disease, Early Onset | Alzheimer Disease, Late Onset | Alzheimer Disease 1 | Alzheimer Disease 2 | Alzheimer Disease 3 | Alzheimer Disease 4 | Alzheimer Disease 7 | Alzheimer Disease 17 | Alzheimer Disease 5 | Alzheimer Disease 6 | Alzheimer Disease 8 | Alzheimer Disease 10 | Alzheimer... and other conditions

United States
The University of Texas Health Science Center at...
National Institute on Aging (NIA)

Recruiting

Sex-specific Determinants of Early-phase Recovery From Skeletal Muscle Disuse (MAC)

Rehabilitation | Atrophy of Muscle Due to Disuse

United States
AriBio Co., Ltd.

Completed

Efficacy and Safety of 26-Week Treatment of AR1001 in Patients With Mild to Moderate Alzheimer's Disease

Mild to Moderate Alzheimer's Disease

United States
Medical College of Wisconsin

Recruiting

Botulinum Toxin A for the Treatment of Chemotherapy Induced Peripheral Neuropathy

Peripheral Neuropathy Due to Chemotherapy

United States
Emory University
Cepheid

Terminated

FMT for MDRO Colonization After Infection in Renal Transplant Recipients (PREMIX)

Infection Due to Resistant Organism

United States
U.S. Army Medical Research and Development Command
Uniformed Services University of the Health Sciences; Meiji Seika Pharma Co...

No longer available

Arbekacin Treatment of Adult Patients With Infections Caused by Multidrug-resistant Bacteria

Infection Due to Resistant Organism

United States
University of Florida
Novartis Pharmaceuticals

Completed

Induction Related BK Viremia in Renal Transplant Patients (BK)

Transplantation Infection | Disease Due to BK Polyomavirus | Disorder Related to Transplantation

United States
Cognition Therapeutics
National Institute on Aging (NIA)

Active, not recruiting

A Study to Evaluate the Safety and Efficacy of CT1812 in Subjects With Mild to Moderate Alzheimer's Disease.

Mild to Moderate Alzheimer's Disease

United States, Australia, Netherlands, Czechia, Spain
Eisai Inc.
Pfizer

Completed

The Effectiveness And Safety Of Donepezil Hydrochloride (E2020) In Subjects With Mild To Severe Alzheimer's Disease Residing In An Assisted Living Facility

Mild to Severe Alzheimer's Disease

United States
Aggredyne, Inc.

Completed

AggreGuide 325 mg. Aspirin Study for Aspirin Induced Platelet Dysfunction

Platelet Dysfunction Due to Aspirin Ingestion

United States
Midwestern Regional Medical Center

Withdrawn

Stromal Vascular Fraction for Treatment of Xerostomia

Xerostomia Due to Radiotherapy (Disorder)

United States
Genelex Corporation

Completed

Drug & Gene Interaction Risk Analysis With & Without Genetic Testing Among Patients Undergoing MTM

Drug Metabolism, Poor, CYP2D6-RELATED | Drug Metabolism, Poor, CYP2C19-RELATED | Cytochrome P450 CYP2D6 Enzyme Deficiency | Cytochrome P450 CYP2C9 Enzyme Deficiency | Cytochrome P450 CYP2C19 Enzyme Deficiency | Poor Metabolizer Due to Cytochrome P450 CYP2D6 Variant | CYP2D6 Polymorphism | Ultrarapid... and other conditions

United States
Echosense Ltd.

Completed

Changes in Doppler Signals From the Lung Due to Cardiac Resynchronization in Heart Failure Patients

Change in LDS Signals Due to Cardiac Synchronization Therapy

United States
Wake Forest University Health Sciences

Completed

Effects of Intramuscular (IM) Oxytocin on Pupil Diameter and Heart Rate Variability (HRV)

Chronic Pain Due to Injury

United States
ALK-Abelló A/S

Active, not recruiting

House Dust Mite Allergy Trial In Children (MATIC)

Allergic Rhinitis Due to Dermatophagoides Farinae | Allergic Rhinitis Due to Dermatophagoides Pteronyssinus | Allergic Rhinitis Due to House Dust Mite

Spain, Russian Federation, United States, Poland, Bulgaria, Canada, France, Germany, Lithuania, Slovakia, Ukraine
University of Kansas Medical Center

Recruiting

Pulmonary Hypertension Biorepository and Registry (PHBR)

Pulmonary Arterial Hypertension | Pulmonary Hypertension | Chronic Thromboembolic Pulmonary Hypertension | Pulmonary Hypertension Due to Left Heart Disease | Pulmonary Hypertension, Primary, 4 | Pulmonary Hypertension, Primary, 2 | Pulmonary Hypertension, Primary, 3 | Pulmonary Hypertension, Primary and other conditions

United States
ICON Bioscience Inc

Terminated

Efficacy and Safety Study of IBI-10090 in Patients Undergoing Cataract Surgery

Inflammatory Reaction Due to Ocular Lens Prosthesis

United States
ALK-Abelló A/S

Completed

Mite Asthma Pediatric Immunotherapy Trial (MAPIT)

Allergic Rhinitis Due to House Dust Mite | Allergic Asthma Due to Dermatophagoides Farinae | Allergic Asthma Due to Dermatophagoides Pteronyssinus

Poland, United Kingdom, Spain, United States, Russian Federation, Hungary, France, Bulgaria, Germany
Eisenhower Army Medical Center

Unknown

Comparison of Two Different Alveolar Ridge Preservation Techniques

Loss of Teeth Due to Extraction

United States
Neumedicines Inc.
Department of Health and Human Services

Completed

Safety and Tolerability of HemaMax™ (rHuIL-12) as Radiation Countermeasure

Hematopoietic Syndrome Due to Acute Radiation Syndrome

United States
Aridis Pharmaceuticals, Inc.

Completed

Safety, Pharmacokinetics and Efficacy of KBSA301 in Severe Pneumonia (S. Aureus)

Pneumonia Due to Staphylococcus Aureus

United States, Belgium, France, Spain

Clinical Trials on Alzheimer Disease 2 Due to Apoe4 Isoform in United States

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