Clinical Trials on Amputation; Traumatic, Hand, at Wrist Level

Total 424 results

Zimmer Biomet

Recruiting

Persona OsseoTi Keel Compatibility Study (Total Knee Arthroplasty)

Rheumatoid Arthritis | Osteoarthritis, Knee | Avascular Necrosis | Traumatic Arthritis | Varus Deformity | Valgus Deformity | Knee Pain Chronic | Polyarthritis | Flexion Deformity of Knee

United States
Rennes University Hospital

Terminated

Self-esteem and Neuro-urological Follow-up in Patients With Spina Bifida or Spinal Cord Injury (ESTIME)

Spina Bifida Aperta | Acquired Traumatic Spinal Cord Injury

France
Centre Oscar Lambret
CTD-CNO; Laboratoire PRISM

Active, not recruiting

Radical Fimbriectomy for Young BRCA Mutation Carriers (Fimbriectomy)

BRCA1 Mutation | BRCA2 Mutation | Hereditary Breast and Ovarian Cancer

France
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Terminated

Precision Medicine for Patients With Identified Actionable Mutations

Lymphoma | Multiple Myeloma | Solid Tumor | Malignant Neoplasm | Mutation Abnormality

United States
Asklepios Biopharmaceutical, Inc.

Recruiting

A Study to Evaluate the Safety of AB-1003 (Previously LION-101) in Subjects With Genetic Confirmation of LGMD2I/R9 (Part1)

Muscular Dystrophy | Limb Girdle Muscular Dystrophy | LGMD2I | LGMD | Limb-Girdle Muscular Dystrophy Type 2 | LGMD2 | FKRP | FKRP Mutation | Fukutin Related Protein

United States
Centre Hospitalier Universitaire, Amiens

Terminated

Validation and Standardization of a Battery Evaluation of the Socio-emotional Functions in Various Neurological Pathologies (GREFEXII)

Stroke | Parkinson Disease | Alzheimer Disease | Traumatic Brain Injury | Huntington Disease | Frontal Dementia

France
Allegheny Singer Research Institute (also known...
ElectroCore INC; Chuck Noll Foundation

Recruiting

Non-invasive Vagal Neurostimulation (nVNS) for Traumatic Brain Injury (TBI)-Induced Acute Respiratory Distress

Traumatic Brain Injury | Acute Respiratory Distress Syndrome | Acute Lung Injury | Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)

United States
Evangelismos Hospital

Recruiting

Intermediate Normal Versus High Normal Oxygen Levels in the Emergency Department for Severe Traumatic Brain Injury (INACHOS)

Traumatic Brain Injury | Acute Respiratory Distress Syndrome | Acute Respiratory Failure | Acute Brain Injury

Greece
DePuy International

Completed

A Randomised Single Centre Study to Compare the Long-term Wear Characteristics of Marathon™ and Enduron™ Polyethylene Cup Liners in Primary Total Hip Replacement

Osteoarthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Traumatic Femoral Fractures | Nonunion of Femoral Fractures

New Zealand
Hacettepe University

Unknown

Turkish Version of The Measure of Processes of Care (MPOC)

Cerebral Palsy | Muscular Dystrophies | Traumatic Brain Injury | Autism Spectrum Disorder | Down Syndrome | Disability Physical | Disability, Developmental
University Hospital, Antwerp
University Hospital, Ghent

Recruiting

Genome-wide Epistasis for Cardiovascular Severity in Marfan Study (GEMS)

Marfan Syndrome | FBN1 Mutation

Belgium
Ascentage Pharma Group Inc.
Merck Sharp & Dohme LLC

Recruiting

A Study of APG-115 in Combination With Pembrolizumab in Patients With Metastatic Melanomas or Advanced Solid Tumors

Melanoma | P53 Mutation | Uveal Melanoma | Cutaneous Melanoma | Mucosal Melanoma | Malignant Peripheral Nerve Sheath Tumors | MPNST | Unresectable or Metastatic Melanoma or Advanced Solid Tumors | MDM2 Gene Mutation

United States, Australia
Murdoch Childrens Research Institute
Royal Children's Hospital; Peter MacCallum Cancer Centre, Australia

Not yet recruiting

A Trial of Targeted Therapies for Patients With Slow-Flow or Fast-Flow Vascular Malformations (TARGET-VM)

Arteriovenous Malformations | Vascular Malformations | MAP2K1 Gene Mutation | PIK3CA-related Overgrowth Spectrum | Vascular Anomalies | Lymphangioma | Lymphatic Malformation | KRAS G12D | Venous Malformation | Vascular Anomaly | KRAS G12C | PI3K Gene Mutation | Slow-Flow Vascular Malformation | Fast-Flow Vascular... and other conditions

Australia
Masonic Cancer Center, University of Minnesota

Recruiting

MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies

Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | AML | Acute Leukemia | Neurofibromatosis 1 | Hematologic Malignancy | Myelodysplasia | Minimal Residual Disease | Chromosome Abnormality | Monosomy 7 | Remission | Somatic Mutation | Cytogenetic Abnormality | TP53 | Fetal Hemoglobin | Intrachromosomal Amplification of Chromosome... and other conditions

United States
Diabetica Solutions Inc.
National Institutes of Health (NIH)

Completed

Shear and Pressure Reducing Insoles for the Diabetic Foot (GlideSoft)

Diabetes | Amputation | Neuropathy | Foot Deformity | Ulceration

United States
Zimmer Biomet

Recruiting

Cemented vs Cementless Persona Keel RCT

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Traumatic Arthritis | Varus Deformity | Valgus Deformity | Knee Pain Chronic | Polyarthritis | Flexion Deformity of Knee

United States
Zimmer Biomet

Active, not recruiting

Persona Total Knee Arthroplasty Outcomes Study

Osteoarthritis | Rheumatoid Arthritis | Traumatic Arthritis | Knee Pain Chronic | Polyarthritis | Avascular Necrosis of the Femoral Condyle | Moderate Varus, Valgus or Flexion Deformities

United States
MicroPort Orthopedics Inc.

Active, not recruiting

Post Market Clinical Follow-Up Study for EVOLUTION® BIOFOAM® Tibia and EVOLUTION® CS/CR Porous Femur

Knee Osteoarthritis | Avascular Necrosis | Degenerative Joint Disease of Knee | Rheumatoid Arthritis of Knee | Correction of Functional Deformity | Traumatic Arthritis of Knee

United States
Region Skane

Recruiting

BioMEL- Diagnostic and Prognostic Factors in Melanoma. (BioMEL)

Melanoma | Mutation | Image | Dysplastic Nevi | Melanoma in Situ | Mole (Dermatology)

Sweden
Eloxx Pharmaceuticals, Inc.

Terminated

A Phase 2 Study of ELX-02 in Patients With Nephropathic Cystinosis

Genetic Disease | Cystinosis | Nonsense Mutation

Canada
McGill University

Not yet recruiting

Examining Capacity Building of Youth With Physical Disabilities to Pursue Participation Following the PREP Intervention.

Cerebral Palsy | Amputation | Spinal Cord Injuries | Spina Bifida | Musculoskeletal Disorder | Juvenile Arthritis

Canada
McGill University
Canadian Institutes of Health Research (CIHR); McMaster University; Drexel University

Not yet recruiting

Downstream Effects of Personalized 'Top-down' Participation-based Interventions Among Youth With Physical Disabilities

Cerebral Palsy | Amputation | Spinal Cord Injuries | Spina Bifida | Musculoskeletal Disorder | Juvenile Arthritis

Canada
OMNI Medical Services, LLC
OMNI Medical Services Inc

Recruiting

Outcomes Mandate National Integration With Cannabis as Medicine (OMNI-Can)

Depression | COVID-19 | Epilepsy | Multiple Sclerosis | Glaucoma | Cancer | Covid19 | Chronic Pain | Parkinson Disease | Inflammatory Bowel Diseases | Hepatitis C | Insomnia | HIV/AIDS | Amyotrophic Lateral Sclerosis | Fibromyalgia | Anxiety | Bipolar Disorder | Seizures | Crohn Disease | Traumatic Brain Injury | Ulcerative Colitis | Sickle... and other conditions

United States
DePuy International

Completed

A Study to Assess the Long-term Performance of SmartSet® HV and SmartSet® GHV Bone Cements in Primary Total Hip Replacement

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Traumatic Femoral Fractures | Nonunion of Femoral Fractures

Slovakia
DePuy International

Terminated

A Single Centre Study to Assess the Long-term Performance of the Pinnacle™ Cup With a Ceramic-on-ceramic Bearing in Primary Total Hip Replacement

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Traumatic Femoral Fractures | Nonunion of Femoral Fractures

Czech Republic
DePuy International

Terminated

A Two Centre Study to Assess the Long-term Performance of the Pinnacle™ Cup With a Metal-on-Metal Bearing in Primary Total Hip Replacement

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Traumatic Femoral Fractures | Nonunion of Femoral Fractures

United Kingdom, Italy
DePuy International

Terminated

A Multi-centre Study to Assess the Long-term Performance of the Summit™ Hip in Primary Total Hip Replacement

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Traumatic Femoral Fractures | Nonunion of Femoral Fractures

China, Hong Kong, Italy, Korea, Republic of, New Zealand
DePuy International

Withdrawn

A Multi-centre Study to Assess the Long-term Performance of the Pinnacle™ Cup With a Polyethylene-on-metal Bearing in Primary Total Hip Replacement

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Traumatic Femoral Fractures | Nonunion of Femoral Fractures
DePuy International

Terminated

A Two Centre Study to Assess the Stability and Long-term Performance of the C-Stem™ AMT in a Total Primary Hip Replacement

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Traumatic Femoral Fractures | Nonunion of Femoral Fractures

United Kingdom
DePuy International

Terminated

A Randomised Single Centre Study to Compare the Long-term Performance of 4 Designs of the DePuy Ultima LX Stem in Primary Total Hip Replacement

Osteoarthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Traumatic Femoral Fractures | Nonunion of Femoral Fractures | Collagen Disorder

United Kingdom
DePuy Orthopaedics

Recruiting

Actis Total Hip System 2 Year Follow-up (Actis14014)

Osteoarthritis | Rheumatoid Arthritis | Congenital Hip Dysplasia | Traumatic Arthritis | Avascular Necrosis of the Femoral Head | Acute Traumatic Fracture of the Femoral Head or Neck | Certain Cases of Ankylosis | Non-union of Femoral Neck Fractures | Certain High Sub-Capital & Femoral Neck Fractures...

United States
Medacta International SA

Recruiting

The Medacta International SMS Post-Marketing Surveillance Study

Arthrosis | Congenital Hip Dysplasia | Traumatic Arthritis | Rheumatoid Polyarthritis | Avascular Necrosis of the Femoral Head

Austria, Italy, Switzerland, United Kingdom
Medacta International SA

Recruiting

The Medacta Quadra-P Anteverted Study

Arthrosis | Congenital Hip Dysplasia | Traumatic Arthritis | Rheumatoid Polyarthritis | Avascular Necrosis of the Femoral Head

Italy
Medacta International SA

Active, not recruiting

The Medacta International AMIStem-P Post-Marketing Surveillance Study

Arthrosis | Congenital Hip Dysplasia | Traumatic Arthritis | Rheumatoid Polyarthritis | Avascular Necrosis of the Femoral Head

France
Zimmer Biomet

Active, not recruiting

Persona Ti-Nidium Post-Market Clinical Follow-up (TKA)

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Patellofemoral Osteoarthritis | Traumatic Arthritis | Varus Deformity | Valgus Deformity | Knee Pain Chronic | Polyarthritis | Flexion Deformity of the Knee

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Embolization of the Middle Meningeal Artery for the Prevention of Chronic Subdural Hematoma Recurrence in High Risk Patients (EMPROTECT) (EMPROTECT)

Chronic Subdural Hematoma | at Risk of Post-operative Recurrence | Burr-hole Surgery

France
University of Washington
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Power Over Pain (POP) Study (POP)

Multiple Sclerosis | Low Back Pain | Chronic Pain | Muscular Dystrophies | Spinal Cord Injury | Other and Unspecified Amputation Stump Complications

United States
Aspira Women's Health

Terminated

Multifactorial Risk Assessment for Breast & Ovarian Cancer Risk Detection (OVA360)

Hereditary Breast and Ovarian Cancer | Adnexal Mass | Germline BRCA1 Gene Mutation | Germline BRCA2 Gene Mutation

United States
Johns Hopkins University
National Cancer Institute (NCI); National Institutes of Health (NIH); ChiRhoClin...

Recruiting

The Cancer of the Pancreas Screening-5 CAPS5)Study (CAPS5)

Lynch Syndrome | Pancreas Cancer | Gene Mutation | Peutz-Jeghers Syndrome (PJS) | Germline Mutation Carrier

United States
Khondrion BV
Julius Clinical; ProPharma Group; Europees Fonds voor Regionale Ontwikkeling... and other collaborators

Active, not recruiting

The KHENERGYC Study

Mitochondrial Diseases | MELAS | Mitochondrial DNA tRNALeu(UUR) m.3243A<G Mutation | Subacute Necrotizing Encephalomyelopathy

Netherlands
University of Alabama at Birmingham
Lakeshore Foundation; YMCA of Greater Birmingham

Active, not recruiting

Movement-2-Music: Lakeshore Examination of Activity, Disability, and Exercise Response Study (M2M LEADERS)

Stroke | Multiple Sclerosis | Cerebral Palsy | Parkinson Disease | Traumatic Brain Injury | Spinal Cord Injuries | Spina Bifida

United States
DePuy International

Terminated

A Randomised Multi-centre Study to Compare the Long-term Performance of the Future Hip to 3 Other Implants in Primary Total Hip Replacement

Osteoarthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Traumatic Femoral Fractures | Nonunion of Femoral Fractures | Perthes Disease

Austria, Germany, Italy
Corin

Active, not recruiting

Corin MiniHip and Trinity Cup Clinical Surveillance Study

Developmental Dysplasia of the Hip | Osteoarthritis, Hip | Total Hip Arthroplasty | Avascular Necrosis of the Femoral Head | Rheumatoid Arthritis of Hip | Traumatic Arthritis of Hip
Corin

Withdrawn

A Comparison of Two Surgical Techniques Using the Unity Knee™ Total Knee System

Rheumatoid Arthritis | Osteoarthritis, Knee | Post-Traumatic Osteoarthritis of Knee | Varus Deformity, Not Elsewhere Classified, Knee | Valgus Deformity, Not Elsewhere Classified, Knee | Flexion Deformity, Knee | Fracture of Distal End of Femur | Fracture of Upper End of Tibia
Assistance Publique - Hôpitaux de Paris

Completed

Osteoporosis in RETT Syndrome (OSRETT)

RETT Syndrome With Proven MECP2 Mutation

France
Khondrion BV
Drug Research Unit Ghent, Belgium

Completed

A Dose-escalating Clinical Trial With KH176

Mitochondrial Disease | MELAS | Leigh Syndrome | LHON | Mitochondrial DNA tRNALeu(UUR) m.3243A<G Mutation

Belgium
National Institute of Allergy and Infectious Diseases...

Terminated

Biochemical Response to Interferon-Gamma in Subjects With Specific Gene Mutation in Chronic Granulomatous Disease

IFN-Gamma Therapy | CGD Gene Mutation | CGD Response to IFNg | CGD - Chronic Granulomatous Disease | Immunodeficiency Disease

United States
University of Kansas

Completed

A Randomized Exercise Trial for Wheelchair Users

Stroke | Multiple Sclerosis | Cerebral Palsy | Arthritis | Muscular Dystrophy | Amputation | Spinal Cord Injury | Spina Bifida

United States
Zimmer Biomet

Active, not recruiting

PMCF Study on the Safety and Performance of the Zimmer® Maxera™ Acetabular System in Total Hip Arthroplasty

Avascular Necrosis | Inflammatory Arthritis | Osteoarthritis, Hip | Congenital Hip Dysplasia | Post-traumatic; Arthrosis | Rheumatoid Arthritis With Adequate Bone Quality

Netherlands, Finland, Belgium, France, Spain, Australia, Canada, United Kingdom
Zimmer Biomet

Active, not recruiting

Vivacit-E Post-market Follow-up Study

Osteoarthritis | Congenital Hip Dysplasia | Post-traumatic; Arthrosis | Avascular Necrosis of Bone of Hip

United States

Clinical Trials on Amputation; Traumatic, Hand, at Wrist Level

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Zambia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations