Clinical Trials on Anal Fissures

Total 1036 results

Ventrus Biosciences, Inc

Unknown

An Open-Label, Single- and Multi-Dose Pharmacokinetic (PK) Study of Oral Diltiazem and Topical Diltiazem Hydrochloride

Adult Subjects With Anal Fissures.

United States
Ventrus Biosciences, Inc

Completed

Efficacy and Safety Study With Diltiazem Hydrochloride Cream to Treat Anal Fissures

Chronic Anal Fissures

United States
University of Palermo

Completed

Oligo-antigenic Diet in the Treatment of Chronic Anal Fissures.

Anal Fissures Treatment and Oligoantigenic Diet

Italy
Solvay Pharmaceuticals

Terminated

Trial to Evaluate Effect of Lactulose on Hard Stools in Patients With Hemorrhoids or Anal Fissures

Hemorrhoids | Anal Fissures

Spain
State Scientific Centre of Coloproctology, Russian...

Recruiting

Surgical Treatment of a Chronic Anal Fissure (STCAF)

Chronic Anal Fissure

Russian Federation
Istanbul Medipol University Hospital

Completed

Effect of Additional Topical Diltiazem on Botulinum Toxin Injection for Chronic Anal Fissure

Anal Fissure Chronic

Turkey
Treviso Regional Hospital

Completed

Efficacy and Safety of Propionibacterium Extract Gel Versus 0.4% Glyceryl Trinitrate Ointment in the Treatment of Chronic Anal Fissure: a Randomised Controlled Trial

Anal Fissure | Anal Fissure Chronic

Italy
Mansoura University

Completed

Transcutaneous Posterior Tibial Nerve Stimulation for Treatment of Chronic Anal Fissure

Chronic Anal Fissure
Hvidovre University Hospital

Unknown

Ultrasound Guided Lateral Sphincterotomy: Long Term Results

Focus: Anal Incontinence After Lateral Sphincterotomy for Chronic Anal Fissure

Denmark
Mansoura University

Unknown

Postero-lateral Internal Sphincterotomy vs Botulinum Toxin Injection in the Treatment of Chronic Anal Fissure

Chronic Anal Fissure

Egypt
Bispebjerg Hospital
Sacomed

Terminated

Treatment Of Chronic Anal Fissure (TOCA)

Chronic Anal Fissure

Denmark
Region Skane

Completed

Percutaneous Tibial Nerve Stimulation - an Alternative Treatment Option for Chronic Therapy Resistant Anal Fissure

Chronic Anal Fissure
S.L.A. Pharma AG

Completed

Diltiazem Hydrochloride Cream for Anal Fissure

Chronic Anal Fissure

United Kingdom, Spain, Bulgaria, Germany, Lithuania, Romania
Zagazig University

Completed

High Dose Multiple Site Injection of Botox Versus Lateral Sphincterotomy in Chronic Analfissure (professor)

Chronic Anal Fissure

Egypt
University of Nineveh

Completed

Outcomes of the Use of CO2 (Carbon Dioxide) Laser in the Treatment of Chronic Anal Fissure

Chronic Anal Fissure
Mansoura University

Completed

Conventional Lateral Internal Sphincterotomy, V-Y Anoplasty and Tailored Lateral Internal Sphincterotomy With V-YF in Treatment of Chronic Anal Fissure(CAF) (CAF)

Chronic Anal Fissure

Egypt
Hospital General Universitario Elche

Completed

Perianal Versus Endoanal Application of Glyceryl Trinitrate 0.4% Ointment for Chronic Anal Fissure

Chronic Anal Fissure

Spain
KTO Karatay University
Istanbul Medipol University Hospital

Completed

Short Term Results of Platelet-rich Plasma in the Treatment of Chronic Anal Fissure

PRP | Anal Fissure Chronic

Turkey
RDD Pharma Ltd

Completed

An Open Label Study to Examine the Effect of Coated Nifedipine Suppository on Anal Fissure Pain and Healing in Human Subjects

Chronic Anal Fissure

Israel
amr bayoumi salama
Cairo University

Enrolling by invitation

Effect of Shock Waves Therapy on Chronic Anal Fissure

Chronic Anal Fissure

Egypt
Sheba Medical Center

Not yet recruiting

Effectiveness of Anal Enlargement by Dilators as a Therapeutic Physical Tool in Acute Anal Fissure

Acute Anal Fissure
RDD Pharma Ltd

Completed

The Effect of Intra-anal Nifedipine, Used As Add-on to Conservative Therapy, on Pain in Patients With Anal Fissure

Chronic Anal Fissure

Bulgaria, Moldova, Republic of, Poland, Romania
State Scientific Centre of Coloproctology, Russian...

Recruiting

Botulinum Toxin Type A in the Treatment of Chronic Anal Fissure (BTATCAF)

Chronic Anal Fissure

Russian Federation
University of Roma La Sapienza

Completed

Pain and Bleeding in Subjects With Acute Anal Fissure: Comparative Evaluation of Three Treatments (PBSAAF)

Acute Anal Fissure

Italy
Hadassah Medical Organization

Unknown

Treatment of Anal Fissure by Activated Human Macrophages

Interventional Study | Biological Therapy for Chronic Anal Fissure | Treatment by Biological Factors - Activated Macrophages

Israel
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Active, not recruiting

Cisplatin and Fluorouracil Compared With Carboplatin and Paclitaxel in Treating Patients With Inoperable Locally Recurrent or Metastatic Anal Cancer (InterAACT)

Anal Squamous Cell Carcinoma | Anal Basaloid Carcinoma | Anal Canal Cloacogenic Carcinoma | Metastatic Anal Canal Carcinoma | Recurrent Anal Canal Carcinoma | Stage IIIB Anal Canal Cancer | Stage IV Anal Canal Cancer

United States
Sun Yat-sen University

Enrolling by invitation

PD-1 Blockade Combined With Chemotherapy Followed by Concurrent Immunoradiotherapy for Locally Advanced SCCA Patients

Anal Canal Cancer | Anal Squamous Cell Carcinoma | Anal Cancer | Anal Canal Cancer Stage I | Anal Canal Cancer Stage II | Anal Canal Cancer Stage III

China
Dieter Hahnloser

Completed

Monocentric Feasibility Study for a New Medical Device for the Treatment of Anal Fissure With Botulinum Toxin

Anal Fissure

Switzerland
Ipsen

Completed

Efficacy Study of Dysport® in the Treatment of Anal Fissure.

Anal Fissure

Czechia, Poland, Romania, Tunisia
Onze Lieve Vrouwe Gasthuis

Completed

Comparison of Treatment Success of Botox Injection in the Internal Sphincter Versus Isosorbidedinitrate Ointment in Patients With an Anal Fissure

Anal Fissure

Netherlands
Biolab Sanus Farmaceutica

Withdrawn

PK, PD and Safety Comparative Trial of Isosorbide Mononitrate Gel in Healthy Participants and With Anal Fissure

Anal Fissure
Pamukkale University

Unknown

Sungurtekin Technique vs. Closed Lateral Internal Sphincterotomy Technique

Anal Fissure
Clinical Centre of Serbia

Completed

A Novel Method for Chronic Anal Fissure Treatment

Anal Fissure
National Cancer Institute (NCI)

Active, not recruiting

Nivolumab With or Without Ipilimumab in Treating Patients With Refractory Metastatic Anal Canal Cancer

Anal Canal Squamous Cell Carcinoma | Metastatic Anal Canal Carcinoma | Stage IV Anal Canal Cancer AJCC v6 and v7

United States, Canada
American University of Beirut Medical Center

Recruiting

Comparative Evaluation of MEBO Ointment and Topical Diltiazem Ointment in the Treatment of Acute Anal Fissure (MEBO)

Anal Fissure

Lebanon
Mansoura University

Completed

Topical Minoxidil Versus Topical Glyceryl Trinitrate in Treatment of Chronic Anal Fissure

Anal Fissure

Egypt
Mansoura University

Completed

Posterolateral Versus Lateral Internal Anal Sphincterotomy for Chronic Anal Fissure

Anal Fissure

Egypt
SB Istanbul Education and Research Hospital

Unknown

The Importance of Lateral Internal Sphincterotomy Incision: Parallel or Vertical

Anal Fissure

Turkey
RDD Pharma Ltd

Terminated

An Open Label Multi-Dose Study to Examine the Effect of Coated Nifedipine Suppository on Anal Fissure Pain and Healing

Anal Fissure

Israel
Forest Laboratories

Withdrawn

Pharmacokinetic,Safety and Exploratory Efficacy of RECTIV® in Adolescents With Chronic Anal Fissure

Anal Fissure

United States
Nepal Mediciti Hospital

Recruiting

Pudendal Nerve Block With Bupivacaine Alone and Bupivacaine With Methylene Blue for Postoperative Analgesia

Hemorrhoids | Perianal Abscess | Perianal Fistula | Pilonidal Sinus | Anal Fissure and Fistula | Perianal Skin Tags

Nepal
Hospital General Universitario Elche

Completed

Application of Vitamin E on Anal Fissure

Pain

Spain
Hospital General Universitario Elche

Completed

Glyceryl Trinitrate Ointment vs Posterior Tibial Nerve Stimulation in the Treatment of Anal Fissure

Pain
Mats Bågesund
Linkoeping University

Completed

Sealing of Occlusal Dentin Caries in Primary Molars. (SealCar)

Dental Caries in Children | Caries; Dentin | Fissure Sealants | Fissure, Dental | Glass Ionomer Cement
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Recruiting

Lower-Dose Chemoradiation in Treating Patients With Early-Stage Anal Cancer, the DECREASE Study

Anal Basaloid Carcinoma | Anal Canal Cloacogenic Carcinoma | Anal Canal Squamous Cell Carcinoma | Anal Margin Squamous Cell Carcinoma | Stage I Anal Cancer AJCC v8 | Stage IIA Anal Cancer AJCC v8

United States
State Scientific Centre of Coloproctology, Russian...
St. Petersburg State Pavlov Medical University; Astrakhan State Medical University and other collaborators

Recruiting

Complex Treatment of a Chronic Anal Fissure

Fissure in Ano

Russian Federation
Mansoura University

Completed

Topical vs Oral Metronidazole After Benign Anorectal Surgery

Anal Fistula | Hemorrhoids | Anal Fissure

Egypt
Aga Khan University

Completed

Retention of Bonded Amalgam Sealants Versus Resin-based Sealants

Fissure, Dental | Incipient Enamel Caries

Pakistan
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

Chemoradiotherapy Combined With or Without PD-1 Blockade in Anal Canal Squamous Carcinoma Patients

Anal Canal Cancer | Anal Squamous Cell Carcinoma | Anal Cancer | Anal Canal Cancer Stage III

China
All India Institute of Medical Sciences, Bhubaneswar

Completed

Efficacy of Polyethylene Glycol vs Lactulose With Isabgol in Acute Fissure-in-Ano: PEGASIS Trial (PEGASIS)

Constipation | Anal Fissure

India

Clinical Trials on Anal Fissures

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