Clinical Trials on Anal Erosion in United Kingdom

Total 360 results

The Cleveland Clinic
Bard Ltd

Completed

Comparative Study Between Two Fecal Management Systems

Anal Erosion

United States
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Active, not recruiting

Cisplatin and Fluorouracil Compared With Carboplatin and Paclitaxel in Treating Patients With Inoperable Locally Recurrent or Metastatic Anal Cancer (InterAACT)

Anal Squamous Cell Carcinoma | Anal Basaloid Carcinoma | Anal Canal Cloacogenic Carcinoma | Metastatic Anal Canal Carcinoma | Recurrent Anal Canal Carcinoma | Stage IIIB Anal Canal Cancer | Stage IV Anal Canal Cancer

United States
University of Portsmouth

Not yet recruiting

The Effect of Chlorhexidine on the Oral Microbiome and Saliva in Dental Erosion

Dental Erosion

United Kingdom
National Cancer Institute (NCI)

Active, not recruiting

Nivolumab With or Without Ipilimumab in Treating Patients With Refractory Metastatic Anal Canal Cancer

Anal Canal Squamous Cell Carcinoma | Metastatic Anal Canal Carcinoma | Stage IV Anal Canal Cancer AJCC v6 and v7

United States, Canada
University of Portsmouth

Enrolling by invitation

The Effect of Nitrate Supplement on the Oral Microbiome and Saliva in Dental Erosion

Dental Erosion

United Kingdom
Oxford Pharmascience Ltd

Completed

Pilot Study of OXP005 to Assess Gastroduodenal Irritation

Gastroduodenal Erosions

United Kingdom
Oxford Pharmascience Ltd
Quotient Clinical

Completed

Pilot Study of OXP001(2) and Brufen in Healthy Subjects

Gastroduodenal Erosions

United Kingdom
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Recruiting

Lower-Dose Chemoradiation in Treating Patients With Early-Stage Anal Cancer, the DECREASE Study

Anal Basaloid Carcinoma | Anal Canal Cloacogenic Carcinoma | Anal Canal Squamous Cell Carcinoma | Anal Margin Squamous Cell Carcinoma | Stage I Anal Cancer AJCC v8 | Stage IIA Anal Cancer AJCC v8

United States
GlaxoSmithKline

Completed

In Vivo Investigation of Initial Stages of Enamel Erosion

Tooth Erosion

United Kingdom
Unilever R&D
University of Bristol Dental Hospital

Completed

Pilot Study Utilising an Impression Technique to Capture in Vivo Images of Teeth

Tooth Erosion

United Kingdom
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Terminated

HPV Vaccine Therapy in Interrupting Progression in Patients With High-Grade Vulvar or Anal Lesions

High Grade Anal Canal Intraepithelial Neoplasia | High Grade Vulvar Squamous Intraepithelial Lesion

United States
GlaxoSmithKline

Completed

Intra Oral Kinetics of Fluoride Containing Dentifrices

Tooth Erosion

United Kingdom
Colgate Palmolive

Completed

Investigate a Varnish to Protect From Erosive Toothwear

Tooth Erosion

United Kingdom
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Linear Energy Transfer (LET)-Optimized Intensity Modulated Proton Therapy (IMPT) as a Component of Definitive Chemoradiation for Newly Diagnosed Squamous Cell Carcinoma of the Anal Canal: a Feasibility Trial

Stage III Anal Cancer AJCC v8 | Anal Canal Squamous Cell Carcinoma | Stage IIB Anal Cancer AJCC v8 | Stage IIIA Anal Cancer AJCC v8 | Stage IIIB Anal Cancer AJCC v8 | Stage IIIC Anal Cancer AJCC v8 | Stage I Anal Cancer AJCC v8 | Stage II Anal Cancer AJCC v8 | Stage IIA Anal Cancer AJCC v8

United States
University of Leeds

Completed

Preliminary Clinical Study of Ultrasound to Measure Enamel Thickness (UMET)

Tooth Erosion

United Kingdom
London North West Healthcare NHS Trust

Recruiting

CArE for OAsI Study: Care Pathways and Anorectal Evaluation for OASI Associated Incontinence (CArE for OAsI)

Anal Incontinence | Faecal Incontinence | Follow-up | Biofeedback | Obstetric Anal Sphincter Injury | Urogynaecology | Urgency | Severe Perineal Trauma | Grade 3 Perineal Tear | Grade 4 Perineal Tear | Deferral Time | Pathways | Review | Endo-anal Ultrasound

United Kingdom
University College, London
University of California, Santa Cruz; Anna Freud National Centre for Children... and other collaborators

Unknown

Testing Self-regulation Effects of a 'Smart Toy'

Emotion Regulation

United Kingdom
Cardiff University

Recruiting

Phase 1b/II Trial of Pembrolizumab Plus IMRT in Stage III/IV Carcinoma of Anus (CORINTH)

Anal Cancer Stage III A | Anal Cancer Stage III B

United Kingdom, Norway
Lewisham and Greenwich NHS Trust

Completed

Diagnosis of Obstetric Anal Sphincter Injuries (OASIs) Using Transperineal Ultrasound Scan (TPUS)

Obstetric Anal Sphincter Injury

United Kingdom
GlaxoSmithKline

Completed

Effect of Fluoride in a Dentifrice on Remineralization of Erosive Lesions

Enamel Erosion

United States
Massachusetts General Hospital
National Cancer Institute (NCI)

Unknown

Concurrent Chemoradiation + 5-FU + Mitomycin-C in Anal Carcinoma

Carcinoma of the Anal Canal

United States
London North West Healthcare NHS Trust

Completed

Primary Repair of Obstetric Anal Sphincter Injuries (OASIS) by Surgeons (PROS Study) (PROS)

Obstetric Anal Sphincter Injury

United Kingdom
Incyte Corporation

Completed

A Study of INCMGA00012 in Squamous Carcinoma of the Anal Canal Following Platinum-Based Chemotherapy (POD1UM-202)

Squamous Cell Carcinoma of Anal Canal

Spain, United Kingdom, United States, Germany, Belgium, France, Denmark, Italy, Norway
Laser Surgery Care
QIAGEN Gaithersburg, Inc

Completed

Hybrid Capture 2 Human Papiloma Virus (HPV) High-Risk Anal DNA Test

Anal Cancer | Anal Canal HPV Infection Diagnosis | Anal Dysplasia Diagnosis

United States
GlaxoSmithKline

Completed

Evaluation of Efficacy of Experimental Gel to Foam Dentifrices in Dental Erosion

Dental Erosion | Acid Wear

United States
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of Arkansas; The Emmes Company, LLC; AIDS and Cancer Specimen Resource

Active, not recruiting

Surgery in Treating Patients With Early Stage Anal Canal or Perianal Cancer and HIV Infection

HIV Infection | Anal Squamous Cell Carcinoma | Stage 0 Anal Canal Cancer | Stage I Anal Canal Cancer

United States
National Cancer Institute (NCI)

Recruiting

EA2176: Phase 3 Clinical Trial of Carboplatin and Paclitaxel +/- Nivolumab in Metastatic Anal Cancer Patients

Anal Canal Cloacogenic Carcinoma | Metastatic Anal Squamous Cell Carcinoma | Recurrent Anal Squamous Cell Carcinoma | Stage III Anal Cancer AJCC v8 | Stage IV Anal Cancer AJCC v8 | Unresectable Anal Squamous Cell Carcinoma | Anal Basaloid Squamous Cell Carcinoma

United States
National Cancer Institute (NCI)

Recruiting

Therapy Adapted for High Risk and Low Risk HIV-Associated Anal Cancer

HIV Infection | Anal Squamous Cell Carcinoma | Anal Canal Cloacogenic Carcinoma | Stage III Anal Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage II Rectal Cancer AJCC v8 | Anal Margin Squamous Cell Carcinoma | AIDS-Related Anal Carcinoma | Rectal Squamous Cell Carcinoma | Stage I Anal Cancer AJCC... and other conditions

United States
Ascopharm Groupe Novasco

Completed

Open, Multicentric Trial Evaluating the Efficacy and the Clinical Tolerance of PA0903 as Root Canal Sealer (PA0903)

Root Canal Obturation

France, United Kingdom
National Cancer Institute (NCI)
Canadian Cancer Trials Group

Active, not recruiting

Nivolumab After Combined Modality Therapy in Treating Patients With High Risk Stage II-IIIB Anal Cancer

Anal Canal Cloacogenic Carcinoma | Stage III Anal Cancer AJCC v8 | Anal Margin Squamous Cell Carcinoma | Stage IIB Anal Cancer AJCC v8 | Anal Basaloid Squamous Cell Carcinoma

United States, Canada
University of Surrey
FrieslandCampina

Completed

Prebiotics and Mental Health: Behavioural

Anxiety | Emotion Regulation

United Kingdom
King's College London
Stony Brook University; University of Oxford; Stanford University

Completed

Intervention Package to Promote Emotion Regulation Strategies in University Students

Anxiety | Emotion Regulation

United Kingdom
Imperial College London

Recruiting

Anal Cancer Risk In Women

Anal Cancer | Human Papilloma Virus | Anal Intraepithelial Neoplasia | Genital Neoplasm | Genital Cancer

United Kingdom
University of Oxford
Medical Research Council; P1vital Products Limited

Completed

Effects of a Single Dose of Bright Light Treatment on Measures of Affective Information Processing

Emotion | Bright Light Treatment | Facial Expression Recognition

United Kingdom
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

4-Point Therapy Response Score With PET/CT for Anal Squamous Cell Cancer

Anal Squamous Cell Carcinoma | Stage III Anal Cancer AJCC v8 | Stage IIB Anal Cancer AJCC v8 | Stage IIIA Anal Cancer AJCC v8 | Stage IIIB Anal Cancer AJCC v8 | Stage IIIC Anal Cancer AJCC v8 | Stage I Anal Cancer AJCC v8 | Stage II Anal Cancer AJCC v8 | Stage IIA Anal Cancer AJCC v8 | Stage 0 Anal Cancer...

United States
Imperial College London

Recruiting

Anal Intraepithelial Neoplasia and Anal Squamous Cell Carcinoma

Anal Cancer | Anal Squamous Intraepithelial Neoplasia

United Kingdom
King's College London
Guy's and St Thomas' NHS Foundation Trust

Unknown

Prevalence of Bacteria Following Endodontic Treatment

Root Canal Infection

United Kingdom
University of Surrey
FrieslandCampina

Recruiting

The Role of the Microbiota-gut-brain Axis in Brain Development and Mental Health

Anxiety | Gamma-Aminobutyric Acid | Glutamate | Emotion Regulation Abilities

United Kingdom
Croydon Health Services NHS Trust

Completed

The Effect of Perineal Wound Infection on the Anal Sphincter

Anal Sphincter Injury | Obstetric Trauma | Perineal Infection | Perineum; Injury

United Kingdom
University of Oxford
National Health and Medical Research Council, Australia; Monash University; Oxford... and other collaborators

Unknown

Gut-brain Axis, Brain Function, and Behaviour.

Anxiety | Magnetic Resonance Imaging | Decision Making | Cortisol | Humans | Emotion | Prebiotics

United Kingdom
King's College London
National Health Service, United Kingdom

Enrolling by invitation

Impact of an Enhanced Sterile Protocol on Root Canal Treatment Outcome

Endodontic Disease | Root Canal Infection | Root Canal Treatment

United Kingdom
University of Edinburgh
NHS Lothian

Completed

Pain Following Root Canal Treatment (PfRCT)

Assessment of Pain After Root Canal Treatment

United Kingdom
King's College London
University of Nottingham; University of Oxford; Stanford University; University... and other collaborators

Recruiting

Purrble With LGBTQ+ Youth Who Have Self-harmful Thoughts

Self Harm | Emotion Regulation

United Kingdom
S.L.A. Pharma AG

Completed

Diltiazem Hydrochloride Cream for Anal Fissure

Chronic Anal Fissure

United Kingdom, Spain, Bulgaria, Germany, Lithuania, Romania
King's College London
Procter and Gamble

Completed

Impact of Dietary Advice on the Progression of Tooth Wear (DAI)

Erosive Tooth Wear

United Kingdom
Procter and Gamble

Completed

Meta-analysis of Stannous Fluoride and the Effects on Enamel Erosion

Enamel Erosion

United States
Cambridge University Hospitals NHS Foundation Trust
The Christie NHS Foundation Trust; Bowel Disease Research Foundation

Unknown

Functional Outcomes Following Anal Cancer Treatment (FOFACT)

Anal Cancer

United Kingdom
Incyte Corporation

Active, not recruiting

Carboplatin-paclitaxel With Retifanlimab or Placebo in Participants With Locally Advanced or Metastatic Squamous Cell Anal Carcinoma (POD1UM-303/InterAACT 2).

Squamous Cell Carcinoma of the Anal Canal

United States, Italy, Spain, United Kingdom, Australia, France, Germany, Sweden, Japan, Norway, Belgium, Denmark, Puerto Rico
London North West Healthcare NHS Trust

Completed

The Impact of 3D Anal Fistula Models on Patient Understanding and Decision Making (3DAF)

Fistula in Ano | Ano Fistula

United Kingdom
PLx Pharma
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Completed

Clinical Trial Evaluating Gastrointestinal Damage Following Administration PL3100 or Naproxen in At-Risk Adults

Erosion | Gastroduodenal Ulcerations

United States

Clinical Trials on Anal Erosion in United Kingdom

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