Clinical Trials on Anal Incontinence

Total 2270 results

Hvidovre University Hospital

Unknown

Ultrasound Guided Lateral Sphincterotomy: Long Term Results

Focus: Anal Incontinence After Lateral Sphincterotomy for Chronic Anal Fissure

Denmark
Groupe Hospitalier Paris Saint Joseph

Completed

Pelvic-perineal Disorders in Women With Sphincter Tears (PAPOASI)

Obstetrical Perineal Injury and Anal Incontinence

France
Assistance Publique Hopitaux De Marseille

Completed

Does Body Position Influence Pressure Recording by High-resolution Manometry ?

Anal Incontinence or Constipation

France
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Active, not recruiting

Cisplatin and Fluorouracil Compared With Carboplatin and Paclitaxel in Treating Patients With Inoperable Locally Recurrent or Metastatic Anal Cancer (InterAACT)

Anal Squamous Cell Carcinoma | Anal Basaloid Carcinoma | Anal Canal Cloacogenic Carcinoma | Metastatic Anal Canal Carcinoma | Recurrent Anal Canal Carcinoma | Stage IIIB Anal Canal Cancer | Stage IV Anal Canal Cancer

United States
Emory University

Completed

Reducing Perinatal Anal Incontinence Through Early Pelvic Floor Muscle Training: a Prospective Pilot Study

Perinatal and Postpartum Anal Incontinence

United States
Sun Yat-sen University

Enrolling by invitation

PD-1 Blockade Combined With Chemotherapy Followed by Concurrent Immunoradiotherapy for Locally Advanced SCCA Patients

Anal Canal Cancer | Anal Squamous Cell Carcinoma | Anal Cancer | Anal Canal Cancer Stage I | Anal Canal Cancer Stage II | Anal Canal Cancer Stage III

China
University Hospital, Angers

Not yet recruiting

Anal Incontinence After Obstetrical Anal Sphincter Injury (INCONT-LOSA)

Anal Sphincter Injury | Anal Incontinence | Obstetric Trauma
Region Skane

Terminated

Treatment of Anal Incontinence With Intersphincteric Implants

Fecal Incontinence | Anal Incontinence

Sweden
San Diego State University
University of California, San Diego

Completed

Physical Therapy for Anal Incontinence

Fecal Incontinence | Anal Incontinence

United States
Karolinska Institutet

Completed

Polyacrylamide Hydrogel Injection Treatment for Anal Incontinence

Anal Incontinence
National Cancer Institute (NCI)

Active, not recruiting

Nivolumab With or Without Ipilimumab in Treating Patients With Refractory Metastatic Anal Canal Cancer

Anal Canal Squamous Cell Carcinoma | Metastatic Anal Canal Carcinoma | Stage IV Anal Canal Cancer AJCC v6 and v7

United States, Canada
Massarat Zutshi
Cook Group Incorporated

Terminated

Comparison of the Efficacy of a Biological Implant to Reinforce Overlapping Sphincter Repair Versus Overlapping Sphincter Repair Alone

Fecal Incontinence | Anal Incontinence

United States
Nantes University Hospital

Suspended

Medical and Economic Evaluation of a Magnetic Anal Sphincter for Patients With Severe Anal Incontinence (MOS STIC)

Fecal Incontinence | Anal Incontinence

France
Herlev Hospital

Unknown

Treatment of Fecal Incontinence by Injection of Autologous Muscle Fibers Into the Anal Sphincter

Fecal Incontinence | Anal Incontinence

Denmark
University Hospital, Rouen

Completed

Does the Negativation of the Glucose Hydrogen Breath Test Come Along With a Reduction of the Symptoms of Gaz Incontinence ?

Anal Incontinence

France
London North West Healthcare NHS Trust

Recruiting

CArE for OAsI Study: Care Pathways and Anorectal Evaluation for OASI Associated Incontinence (CArE for OAsI)

Anal Incontinence | Faecal Incontinence | Follow-up | Biofeedback | Obstetric Anal Sphincter Injury | Urogynaecology | Urgency | Severe Perineal Trauma | Grade 3 Perineal Tear | Grade 4 Perineal Tear | Deferral Time | Pathways | Review | Endo-anal Ultrasound

United Kingdom
Escola Bahiana de Medicina e Saude Publica

Unknown

Radiofrequency in Anal Incontinence: Randomized Clinical Trials

Radiation Exposure

Brazil
Hospices Civils de Lyon

Terminated

ORALIA Trial Medical Treatment vs Anoperineal Physiotherapy for Adult Anal Incontinence.

Anal Incontinence

France
University Hospital, Montpellier

Recruiting

Perineal Trauma After Jet Ski Accidents and Long-term Functional Outcomes Results (TP-JET)

Anal Incontinence | Perineum; Tear, Traumatic | Anal Tear

France
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Recruiting

Lower-Dose Chemoradiation in Treating Patients With Early-Stage Anal Cancer, the DECREASE Study

Anal Basaloid Carcinoma | Anal Canal Cloacogenic Carcinoma | Anal Canal Squamous Cell Carcinoma | Anal Margin Squamous Cell Carcinoma | Stage I Anal Cancer AJCC v8 | Stage IIA Anal Cancer AJCC v8

United States
University of Pecs

Recruiting

Anal Incontinence and Its Impact on Quality of Life and Physical Activity Among Hungarian Women and the Hungarian Language Validation of the International Consultation on Incontinence Modular Questionnaire-Bowels (ICIQ-B)

Anal Incontinence

Hungary
Hospital de Transplante Doutor Euryclides de Jesus...

Completed

Effects of High-Intensity Focused Ultrasound (HIFU) Treatment on Fecal Continence and Anorretal Fisiology

Anal Continence After High-Intensity Focused Ultrasound (HIFU) Treatment

Brazil
Groupe Hospitalier Paris Saint Joseph
Hôpital Louis Mourier

Withdrawn

Crohn and Anal Incontinence (CRIA)

Crohn Disease
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

Chemoradiotherapy Combined With or Without PD-1 Blockade in Anal Canal Squamous Carcinoma Patients

Anal Canal Cancer | Anal Squamous Cell Carcinoma | Anal Cancer | Anal Canal Cancer Stage III

China
Mansoura University

Completed

Idiopathic Hypertensive Anal Canal: a Place of Internal Sphincterotomy

Hypertensive Anal Canal

Egypt
Hadassah Medical Organization

Completed

Risk Factors for Anal Sphincter Damage During Vaginal Delivery (AnaSphRF)

Anal Sphincter Injury | Fecal Incontinence

Israel
Poitiers University Hospital

Recruiting

Mediolateral Episiotomy and Obstetric Anal Sphincter Injuries in Instrumental Delivery (INSTRUMODA)

Depression | Pelvic Floor Disorders | Anal Incontinence | Episiotomy Wound | Obstetric Anal Sphincter Injury

France
AHS Cancer Control Alberta

Unknown

A Phase II Study to Assess Acute Toxicity and Quality of Life of Patients With Carcinoma of the Anal Canal Receiving Chemotherapy and Radiation Using Helical Tomotherapy

Anal Canal Cancer

Canada
Institut d'Investigació Biomèdica de Girona Dr....

Completed

Severity of Fecal Incontinence and Manometric Values Using the Anopress® Device in Women (MANOPRESS)

Fecal Incontinence | Anal; Sphincter, Incontinence | Incontinence, Urge

Spain
Oslo University Hospital

Enrolling by invitation

Pelvic Floor Function After Obstetric Injury to the Anal Sphincter (PFF)

Urinary Incontinence | Sexual Dysfunction | Anal Incontinence | Obstetric Anal Sphincter Injury

Norway
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Terminated

HPV Vaccine Therapy in Interrupting Progression in Patients With High-Grade Vulvar or Anal Lesions

High Grade Anal Canal Intraepithelial Neoplasia | High Grade Vulvar Squamous Intraepithelial Lesion

United States
Dr. Te Vuong
YM BioSciences

Terminated

Nimotuzumab With Radiotherapy in the Treatment of Anal Canal Cancers

Squamous Cell Carcinoma of Anal Canal

Canada
Institut Cancerologie de l'Ouest

Completed

Medico-economic Evaluation Comparing Intensity-Modulated Radiation Therapy (IMRT) Performed by Helical Tomotherapy and Dynamic Arc Therapy in Prostate, Cervical and Anal Canal Cancers (RCMI PELVIS)

Cervical Cancer | Prostate Cancer | Anal Canal Cancers

France
University of North Carolina, Chapel Hill
Allergan

Withdrawn

Effects of Eluxadoline (Viberzi®) 100 mg Twice Daily on Diarrhea-Associated Fecal Incontinence (ELXDFI)

Diarrhea | Fecal Incontinence | Urge Incontinence | Anal Incontinence | Accidental Bowel Leakage
Centre Francois Baclesse
Accuray Incorporated

Active, not recruiting

Study of SIB-IMRT in Combination With 5-FU and Mitomycin-C Among Patients With Locally Advanced Anal Canal Cancer: Efficacy, Safety and Quality of Life (CANAL-IMRT-01)

Locally Advanced Anal Canal Cancer

France
University of Monastir

Completed

Urinary and Anal Incontinence in Tunisian Women

Woman

Tunisia
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Linear Energy Transfer (LET)-Optimized Intensity Modulated Proton Therapy (IMPT) as a Component of Definitive Chemoradiation for Newly Diagnosed Squamous Cell Carcinoma of the Anal Canal: a Feasibility Trial

Stage III Anal Cancer AJCC v8 | Anal Canal Squamous Cell Carcinoma | Stage IIB Anal Cancer AJCC v8 | Stage IIIA Anal Cancer AJCC v8 | Stage IIIB Anal Cancer AJCC v8 | Stage IIIC Anal Cancer AJCC v8 | Stage I Anal Cancer AJCC v8 | Stage II Anal Cancer AJCC v8 | Stage IIA Anal Cancer AJCC v8

United States
Centre Hospitalier Universitaire de Besancon

Completed

Evaluation of Immune Response Against Human Papillomavirus (HPV)in Patients With Metastatic Cancer of the Anal Canal (Epitopes-HPV01)

Metastatic Anal Canal Cancer | Human Papillomavirus

France
University Hospital, Umeå

Recruiting

Multicenter Study for Diagnosis and Treatment of Perianal Abscesses

Perianal Abscess | Incontinence | Anal Fistulas

Sweden
Central Hospital, Nancy, France

Completed

Impact of Bariatric Surgery in Patients With Morbid Obesity (IVBIA)

Obesity, Morbid | Anal Incontinence | Image, Body

France
Hanna Jangö

Completed

Translation and Validation of the ICIQ-B in Danish

Quality of Life | Pelvic Floor Disorders | Anal Incontinence | Anal Sphincter Tear

Denmark
Centre Hospitalier Universitaire de Besancon

Withdrawn

Immunomonitoring and Biomarker Research in Patients With Squamous Cell Anal Carcinoma (LAND)

Anal Canal Cancer

France
National Cancer Institute (NCI)

Recruiting

EA2176: Phase 3 Clinical Trial of Carboplatin and Paclitaxel +/- Nivolumab in Metastatic Anal Cancer Patients

Anal Canal Cloacogenic Carcinoma | Metastatic Anal Squamous Cell Carcinoma | Recurrent Anal Squamous Cell Carcinoma | Stage III Anal Cancer AJCC v8 | Stage IV Anal Cancer AJCC v8 | Unresectable Anal Squamous Cell Carcinoma | Anal Basaloid Squamous Cell Carcinoma

United States
AHS Cancer Control Alberta

Recruiting

Inguinal Node Sparing Radiotherapy For Patients With Early Stage Anal Cancer (INSPIRE)

Anal Canal Cancer

Canada
National Cancer Institute (NCI)
Canadian Cancer Trials Group

Active, not recruiting

Nivolumab After Combined Modality Therapy in Treating Patients With High Risk Stage II-IIIB Anal Cancer

Anal Canal Cloacogenic Carcinoma | Stage III Anal Cancer AJCC v8 | Anal Margin Squamous Cell Carcinoma | Stage IIB Anal Cancer AJCC v8 | Anal Basaloid Squamous Cell Carcinoma

United States, Canada
Centre Hospitalier Universitaire de la Réunion
Institut National de la Santé Et de la Recherche Médicale, France; CIC-EC Réunion

Completed

Prenatal Pelvic Floor Prevention (3PN)

Urinary Incontinence | Anal Incontinence | Genital Prolapse

France
Massachusetts General Hospital
National Cancer Institute (NCI)

Unknown

Concurrent Chemoradiation + 5-FU + Mitomycin-C in Anal Carcinoma

Carcinoma of the Anal Canal

United States
National Cancer Institute (NCI)

Recruiting

Therapy Adapted for High Risk and Low Risk HIV-Associated Anal Cancer

HIV Infection | Anal Squamous Cell Carcinoma | Anal Canal Cloacogenic Carcinoma | Stage III Anal Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage II Rectal Cancer AJCC v8 | Anal Margin Squamous Cell Carcinoma | AIDS-Related Anal Carcinoma | Rectal Squamous Cell Carcinoma | Stage I Anal Cancer AJCC... and other conditions

United States
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of Arkansas; The Emmes Company, LLC; AIDS and Cancer Specimen Resource

Active, not recruiting

Surgery in Treating Patients With Early Stage Anal Canal or Perianal Cancer and HIV Infection

HIV Infection | Anal Squamous Cell Carcinoma | Stage 0 Anal Canal Cancer | Stage I Anal Canal Cancer

United States
Instituto do Cancer do Estado de São Paulo

Completed

A Study of Substitution of 5-FU (Fluorouracil) by Capecitabine in Scheme of Chemo-radiotherapy in Patients With Squamous Cell Carcinoma of the Anal Canal.

Anal Canal Cancer.

Brazil

Clinical Trials on Anal Incontinence

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