Clinical Trials on Analgesic Drug Dependence in Canada

Total 280 results

St. Justine's Hospital

Completed

Dexmedetomine as Adjuvant for Spinal Anesthesia in Elective Cesarian Sections : a Pilot Study

Analgesia | Dexmedetomidine | Anesthesia, Spinal | Anesthesia, Obstetrical | Analgesics, Opioid | Analgesics, Non-Narcotic | Analgesia, Obstetrical

Canada
Empower Research Inc

Completed

Exploring Medically Perceived Benefits, Use and Interest in Psychedelics and Cannabinoids (EMPOWER)

Depressive Disorder | Depression | PTSD | Anxiety Disorders | Anxiety | Psychological | Psychedelic Experiences | Psychedelic Drug Dependence

Canada
University of Calgary

Recruiting

Novel Use of Probenecid to Alleviate Symptoms of Opioid Withdrawal

Chronic Pain | Drug Dependence of Morphine Type | Symptom, Withdrawal

Canada
Centre de Recherche de l'Institut Universitaire...
Canadian Institutes of Health Research (CIHR); Université de Sherbrooke; Laval... and other collaborators

Completed

How to Ease the Withdrawal of Tranquilizers Among Older Consumers?

Drug Dependence

Canada
University of Saskatchewan

Recruiting

Effect of Multimodal Opioid-free Anesthesia on Return of Bowel Function in Laparoscopic Colorectal Surgery (RUMBLE)

Laparoscopic Surgery | Analgesia | Colorectal Surgery | Anesthesia | Ketamine | General Anesthesia | Dexmedetomidine | Postoperative Ileus | Analgesics, Opioid | Lidocaine | Opioid Free Anesthesia

Canada
University of Calgary
Alberta Health services

Completed

Delivering Contingency Management in Outpatient Addiction Treatment (PRISE)

Contingency Management | Substance Use | Methamphetamine-dependence | Substance Use Disorders | Substance Abuse | Drug Use | Methamphetamine | Drug Abuse | Adults | Methamphetamine Abuse | Humans

Canada
Sunnybrook Health Sciences Centre
University Health Network, Toronto

Completed

Effect of an Automated Paging System on Response to Critical Laboratory Values

Drug Drug Interactions | Critical Laboratory Values | Drug Laboratory Interactions

Canada
Antios Therapeutics, Inc

Completed

A Drug-Drug Interaction Study Between ATI-2173 and Midazolam or Clarithromycin in Healthy Subjects

Drug Drug Interaction

Canada
Lawson Health Research Institute

Terminated

Pulsatile Pressure Waveform to Confirm Correct Placement of the Epidural in Laboring Patients

Analgesia, Epidural

Canada
Sunnybrook Health Sciences Centre
University Health Network, Toronto; McMaster University; London Health Sciences...

Recruiting

Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients (CODEX)

Mental Disorders | Nervous System Diseases | Neurologic Manifestations | Delirium | Confusion | Neurobehavioral Manifestations | Neurocognitive Disorders | Cognitive Dysfunction | Dexmedetomidine | Molecular Mechanisms of Pharmacological Action | Signs and Symptoms | Physiological Effects of Drugs | Analgesics,... and other conditions

Canada
Centre for Addiction and Mental Health

Not yet recruiting

ACT for Methamphetamine Use Disorder in Women and Gender Non-Conforming Individuals

Methamphetamine-dependence | Methamphetamine Abuse

Canada
University of Alberta

Terminated

Catheter-over Needle: Outpatient Study

Analgesia | Local Anesthesia

Canada
Ottawa Hospital Research Institute
McGill University; Canadian Institutes of Health Research (CIHR)

Completed

Information Systems-enabled Outreach Program for Adverse Drug Events (ISTOP-ADE)

Adverse Drug Events

Canada
McGill University
Canadian Institutes of Health Research (CIHR)

Completed

Using Novel Canadian Resources to Improve Medication Reconciliation at Discharge

Adverse Drug Events | Medication Reconciliation

Canada
Westview Physician Collaborative

Completed

Eliminating Risk of Preventable Adverse Drug Events at the Hospital-community Interface of Care (CMR)

Adverse Drug Events

Canada
University of Saskatchewan

Completed

Chlorhexidine Versus Povidone-Iodine for Prevention of Epidural Needle Contamination in the Parturient

Anesthesia, Epidural | Analgesia, Epidural | Asepsis

Canada
University of British Columbia
Eli Lilly and Company; Merck Sharp & Dohme LLC; Pfizer; Canadian Institutes of... and other collaborators

Recruiting

National Active Surveillance Network and Pharmacogenomics of Adverse Drug Reactions in Children

Adverse Drug Reaction (ADR)

Canada
SignalChem Lifesciences Corporation
Syneos Health

Completed

Crossover Study to Evaluate the Effect of Food on the Pharmacokinetics of SLC-391 in Healthy Adult Subjects

Food-drug Interaction

Canada
Antios Therapeutics, Inc

Completed

A Drug-Drug Interaction Study Between ATI-2173 and Tenofovir Disoproxil Fumarate in Healthy Subjects

Drug Interaction

Canada
Sunnybrook Health Sciences Centre

Completed

Comparing Postoperative Functional Recovery and Analgesic Efficacy of a Single Shot Sciatic Nerve Block Versus Posterior Capsule/Fat Pad Infiltration of Local Anesthetic for Total Knee Arthroplasty

Total Knee Arthroplasty | Post Operative Analgesia

Canada
University of Cincinnati
National Institute on Drug Abuse (NIDA)

Completed

Safety Assessment of Potential Interactions Between IV Methamphetamine and Osmotic-Release Methylphenidate (OROS-MPH)

Methamphetamine Dependence | Methamphetamine Abuse

United States, Canada
Desitin Arzneimittel GmbH
BioPharma Services, Inc

Completed

Bioavailability and Food Effect of Sodium Valproate Minitablets in Healthy Subjects.

Food-drug Interaction

Canada
Emalex Biosciences Inc.
Syneos Health; Cambridge Cognition Ltd

Recruiting

Drug Interaction Study

Drug Interaction

Canada
Abbott

Completed

A Study to Evaluate the Interaction Between Vicodin® CR and Ethanol in Healthy Male and Female Moderate Alcohol Drinkers

Drug Interactions

Canada
Centre for Addiction and Mental Health

Completed

Using Non-invasive Brain Stimulation (tDCS) With Varenicline for Treating Tobacco Dependence

Smoking Cessation | Tobacco Smoking | Tobacco Use Disorder | Substance Use Disorders | Molecular Mechanisms of Pharmacological Action | Tobacco Dependence | Physiological Effects of Drugs

Canada
Desitin Arzneimittel GmbH
BioPharma Services, Inc

Completed

Bioavailability of Orfiril Long 500 mg Prolonged-Release Minitablets and Ergenyl Chrono 500 mg Prolonged-Release Tablets

Multiple Drug Use

Canada
University Health Network, Toronto

Completed

Effect of Remifentanil Boluses on Hemodynamics in Skull Pin Insertion

Skull Pin Insertion | Short Duration Analgesia

Canada
Centre for Addiction and Mental Health
Canadian Institutes of Health Research (CIHR)

Completed

Use of Pharmacotherapy to Reduce Cue-responsiveness in Smokers

Nicotine Dependence | Tobacco Dependence

Canada
Nova Scotia Health Authority

Unknown

In Vivo Lithium Treatment Effects on Gene Expression Levels in Lymphoblastoid Cell Lines From Human Healthy Subjects

Drug Mechanism

Canada
University of British Columbia
BC Centre on Substance Use

Terminated

The Impact of Alternative Social Assistance Disbursement on Drug-related Harm (TASA)

Drug Use

Canada
Lawson Health Research Institute

Completed

Coffee Interaction With the Antihypertensive Drug Felodipine

Food-Drug Interactions

Canada
Centre hospitalier de l'Université de Montréal...
Centre de Recherche du Centre Hospitalier de l'Université de Montréal

Completed

Drug-drug Interaction Study in Healthy Male Volunteers Following the Administration of Pantoprazole and Rosuvastatin

Drug Interaction Potentiation

Canada
University of British Columbia
Genome British Columbia; Genome Canada; Dynacare Laboratories, Inc.

Recruiting

Integrating Pediatric Pharmacogenomic Testing Into the Canadian Health Care System

Adverse Drug Reaction (ADR)

Canada
Akebia Therapeutics

Completed

Drug-Drug Interaction Study of Vadadustat With Digoxin, Adefovir and Furosemide

Drug Interaction Potentiation

Canada
University of Alberta

Terminated

Comparing Ilioinguinal Single-shot and Three-layer Blocks

Local Anesthesia | Post-operative Analgesia | Ilioinguinal Nerve Block

Canada
University Health Network, Toronto

Completed

Distance for Interscalene Block

Post Operative Analgesia | Regional Anesthesia | Inter Scalene Block

Canada
University Health Network, Toronto

Completed

Does Interneural Local Anesthetic Spread at the Site of Sciatic Nerve Bifurcation Shorten Block Onset Time?

Post Operative Analgesia | Regional Anesthesia | Sciatic Nerve Block

Canada
Akebia Therapeutics

Completed

Drug-Drug Interaction Study of Vadadustat With Rosuvastatin, Sulfasalazine, Pravastatin, Atorvastatin and Simvastatin

Drug Interaction Potentiation

Canada
Akebia Therapeutics

Completed

Drug-Drug Interaction Study of Vadadustat With Cyclosporine, Probenecid and Rifampin

Drug Interaction Potentiation

Canada
Centre for Addiction and Mental Health
Canadian Institutes of Health Research (CIHR)

Completed

Effect of Varenicline on Reactivity to Smoking and Drinking Cues

Alcohol Dependence | Tobacco Dependence

Canada
Centre de recherche du Centre hospitalier universitaire...
Lallemand Health Solutions

Completed

Validation of the In-utero Transmission of Probiotics (PROBIO)

In Utero Drug Exposure

Canada
Centre for Addiction and Mental Health

Completed

A Dietary Supplement for Early Cigarette Withdrawal (CIGAR)

Nicotine Dependence, Cigarettes, With Withdrawal

Canada
St. Justine's Hospital
CIUSSS du Nord-de-l'Île-de-Montréal

Recruiting

Monitoring of Metabolic Adverse Events of Second Generation Antipsychotics in a Naive Pediatric Population (MEMAS)

Adverse Drug Event

Canada
Université de Sherbrooke

Recruiting

Effects of an Educational Tool on Knowledge and Risk Retention About Epidural Analgesia in Parturients.

Analgesia, Epidural

Canada
Royal Victoria Hospital, Canada

Unknown

Do Epidurals Placed at a Lower Level Improve Labor Analgesia?

Labor Analgesia

Canada
The Hospital for Sick Children
St. Justine's Hospital

Completed

Deep Brain Stimulation Post Failed Vagal Nerve Stimulation (DBSpostVNS)

Epilepsy, Drug Resistant

Canada
Dr. Glenio Mizubuti (MD, MSc)

Recruiting

Near Remote Method to Guide Performance of Regional Anesthesia

Analgesia | Anesthesia | Nerve Block | Delivery of Healthcare | Hospitals, Teaching

Canada
Lawson Health Research Institute
University of Western Ontario, Canada

Completed

Trial of Onset of Epidural Pain Relief With Low Dose Bupivacaine and Different Doses of Fentanyl in Laboring Women

Anesthetic, Sedative or Analgesic Complications in Labor or Delivery

Canada
University of British Columbia

Completed

A Comparison of Epidural Techniques for Labour Analgesia

Labour Analgesia

Canada
University of British Columbia
Canadian Institutes of Health Research (CIHR); Providence Healthcare; Innerchange...

Completed

Study to Assess Longer-term Opioid Medication Effectiveness (SALOME) (SALOME)

Heroin Dependence | Opioid Dependence

Canada

Clinical Trials on Analgesic Drug Dependence in Canada

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Mauritania

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Rare Diseases

Drug Interventions

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