Clinical Trials on Analgesics, Opioids in Canada

Total 118 results

University of Saskatchewan

Recruiting

Effect of Multimodal Opioid-free Anesthesia on Return of Bowel Function in Laparoscopic Colorectal Surgery (RUMBLE)

Laparoscopic Surgery | Analgesia | Colorectal Surgery | Anesthesia | Ketamine | General Anesthesia | Dexmedetomidine | Postoperative Ileus | Analgesics, Opioid | Lidocaine | Opioid Free Anesthesia

Canada
St. Justine's Hospital

Completed

Dexmedetomine as Adjuvant for Spinal Anesthesia in Elective Cesarian Sections : a Pilot Study

Analgesia | Dexmedetomidine | Anesthesia, Spinal | Anesthesia, Obstetrical | Analgesics, Opioid | Analgesics, Non-Narcotic | Analgesia, Obstetrical

Canada
Blake Raggio
University of Toronto

Unknown

Celecoxib vs. Acetaminophen/Codeine/Caffeine for Post-operative Analgesia in Rhinoplasty.

Pain, Postoperative | Surgery--Complications | Opioid Use | Opioid Analgesic Adverse Reaction

Canada
Ankara City Hospital Bilkent

Completed

Comparison of the Intraoperative and Postoperative Effects of Ultrasound-guided Erector Spina Plane Block and Posterior Quadratus Lumborum Block in Patients Undergoing Lumbar Stabilization Surgery

Quadratus Lumborum Block | Opioid Consumption | Postprocedural Analgesia | Erector Spina Plan Block

Turkey
University of Manitoba

Completed

Evaluation of a Patient-Centred, Multidisciplinary Opioid Tapering Program for Individuals With Chronic Non-Cancer Pain on Long Term Opioid Therapy

Opioid Use | Pain, Chronic | Hyperalgesia | Opioids; Harmful Use

Canada
St. Justine's Hospital

Withdrawn

A RCT of a Combination of Analgesics for Pain Management in Children With a Suspected Fracture (CAST)

Acute Pain | Fentanyl | Analgesics, Opioid | Emergency Service, Hospital | Ibuprofen | Child/Adolescent Problem | Anti-inflammatory Agents, Non-steroidal

Canada
University of Saskatchewan

Completed

Efficacy of Opioid-free Anesthesia in Reducing Postoperative Respiratory Depression in Children Undergoing Tonsillectomy

Pathologic Processes | Postoperative Complications | Sleep Disordered Breathing | Anesthesia | Ketamine | General Anesthesia | Dexmedetomidine | Tonsillectomy | Respiratory Depression | Analgesics, Opioid | Pulse Oximetry | Lidocaine | Analgesics | Gabapentin | Narcotics | Obstructive Sleep Apnea of Child | Physiologic Effects...

Canada
Lawson Health Research Institute

Terminated

Pulsatile Pressure Waveform to Confirm Correct Placement of the Epidural in Laboring Patients

Analgesia, Epidural

Canada
University of Alberta

Terminated

Catheter-over Needle: Outpatient Study

Analgesia | Local Anesthesia

Canada
University Health Network, Toronto
Ontario Ministry of Health and Long Term Care

Completed

Surgical Patient Knowledge and Safe Use of Opioids

Opioid Use

Canada
University Health Network, Toronto

Completed

Improving Surgical Patient Knowledge and Safe Use of Opioids

Opioid Use

Canada
Hamilton Health Sciences Corporation
McMaster University

Terminated

Perioperative Pregabalin for Reducing Opioid Consumption After Cardiac Surgery (OPIATE)

Opioid Use

Canada
Timothy Smith

Completed

The Evaluation of Safety and Tolerance of Commercially Available Naltrexone Administered Daily - Assessment for CBRN Operations (TEST CANADA)

Opioid Intoxication

Canada
University of Saskatchewan

Completed

Chlorhexidine Versus Povidone-Iodine for Prevention of Epidural Needle Contamination in the Parturient

Anesthesia, Epidural | Analgesia, Epidural | Asepsis

Canada
Masimo Corporation

Terminated

Feasibility and Acceptability of Oxygen Saturation Monitoring Using Masimo SafetyNet Alert (MSNA) in a Supportive Housing Program

Opioid Use

Canada
Unity Health Toronto
University of Toronto; Toronto Public Health; Ontario College of Art and Design...

Withdrawn

Surviving Opioid Overdose With Naloxone Education and Resuscitation Trial (SOONER) (SOONER)

Opioid-Related Disorders | Opioid Use | Education | Opioid Withdrawal | Opioid Overdose | Resusitation

Canada
Sunnybrook Health Sciences Centre

Completed

Comparing Postoperative Functional Recovery and Analgesic Efficacy of a Single Shot Sciatic Nerve Block Versus Posterior Capsule/Fat Pad Infiltration of Local Anesthetic for Total Knee Arthroplasty

Total Knee Arthroplasty | Post Operative Analgesia

Canada
University Health Network, Toronto

Recruiting

Opioid Use Post-Discharge After Ambulatory Distal Arm Surgery

Opioid Use

Canada
University Health Network, Toronto

Completed

Effect of Remifentanil Boluses on Hemodynamics in Skull Pin Insertion

Skull Pin Insertion | Short Duration Analgesia

Canada
BC Centre on Substance Use
Indivior Inc.

Recruiting

Extended-release Injectable Buprenorphine for Individuals at High Risk of Overdose (FASTER-BUP)

Opioid Overdose | Opioid-Use Disorder

Canada
University of Alberta

Terminated

Comparing Ilioinguinal Single-shot and Three-layer Blocks

Local Anesthesia | Post-operative Analgesia | Ilioinguinal Nerve Block

Canada
University Health Network, Toronto

Completed

Distance for Interscalene Block

Post Operative Analgesia | Regional Anesthesia | Inter Scalene Block

Canada
University Health Network, Toronto

Completed

Does Interneural Local Anesthetic Spread at the Site of Sciatic Nerve Bifurcation Shorten Block Onset Time?

Post Operative Analgesia | Regional Anesthesia | Sciatic Nerve Block

Canada
Lawson Health Research Institute
University of Western Ontario, Canada

Completed

Trial of Onset of Epidural Pain Relief With Low Dose Bupivacaine and Different Doses of Fentanyl in Laboring Women

Anesthetic, Sedative or Analgesic Complications in Labor or Delivery

Canada
AstraZeneca
Altasciences Company Inc.

Completed

A Safety Study of AZD4041 in Healthy Participants

Opioid Use Disorder (OUD)

Canada
Université de Sherbrooke

Recruiting

Effects of an Educational Tool on Knowledge and Risk Retention About Epidural Analgesia in Parturients.

Analgesia, Epidural

Canada
Royal Victoria Hospital, Canada

Unknown

Do Epidurals Placed at a Lower Level Improve Labor Analgesia?

Labor Analgesia

Canada
Sunnybrook Health Sciences Centre
University Health Network, Toronto; McMaster University; London Health Sciences...

Recruiting

Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients (CODEX)

Mental Disorders | Nervous System Diseases | Neurologic Manifestations | Delirium | Confusion | Neurobehavioral Manifestations | Neurocognitive Disorders | Cognitive Dysfunction | Dexmedetomidine | Molecular Mechanisms of Pharmacological Action | Signs and Symptoms | Physiological Effects of Drugs | Analgesics,... and other conditions

Canada
Dr. Glenio Mizubuti (MD, MSc)

Recruiting

Near Remote Method to Guide Performance of Regional Anesthesia

Analgesia | Anesthesia | Nerve Block | Delivery of Healthcare | Hospitals, Teaching

Canada
University of British Columbia

Withdrawn

The Mobile Monitoring of Vital Signs in Opioid Users (MOVE)

Opioid Use Disorders

Canada
University of British Columbia

Completed

A Comparison of Epidural Techniques for Labour Analgesia

Labour Analgesia

Canada
University of British Columbia

Unknown

Ametop Compared to Ametop With Pain Ease Spray

Analgesia | Topical Anesthetic

Canada
University of British Columbia

Completed

Labour Analgesia and Movement in Babies (LAMB)

Labour Analgesia and Neonate Activity

Canada
Royal Victoria Hospital, Canada

Not yet recruiting

Monthly Versus Daily Buprenorphine Formulations for Treatment of Opiate Use Disorder (STOPIT)

Moderate to Severe Opioid Use Disorder

Canada
Queen's University

Completed

Bupivacaine Levels in Liver Resection Patients

Hepatectomy | Analgesia, Epidural

Canada
Pouya Azar

Recruiting

Symptom-inhibited Fentanyl Induction (SIFI)

Opioid Use Disorder

Canada
University Health Network, Toronto

Recruiting

Reducing Opioid Use for Chronic Pain Patients Following Surgery (RECOUP)

Chronic Pain | Postoperative Pain | Opioid Dependence | Opioid Use

Canada
Pocket Naloxone Corp

Completed

Pharmacokinetic Evaluation of a New Naloxone Nasal Swab, Naloxone Nasal Spray, and Intramuscular Naloxone Injection in Healthy Volunteers

Opioid Overdose

Canada
Centre for Addiction and Mental Health
The Physicians' Services Incorporated Foundation

Completed

rTMS for Suicidality in Opioid Use Disorder

Major Depressive Disorder | Opioid-use Disorder

Canada
Trevi Therapeutics
Syneos Health

Completed

Oral Abuse Potential Study of Nalbuphine

Opioid Abuse | Nalbuphine

Canada
Women's College Hospital

Completed

Access to Primary Care for People With Opioid Use Disorder

Access to Primary Care

Canada
Nova Scotia Health Authority

Recruiting

Personalization of Opioid Prescription Following Orthognathic Surgery

Pain, Postoperative | Opioid Use Disorder | Patient Satisfaction | Opioid Use | Orthognathic Surgery

Canada
University of British Columbia
Vancouver Coastal Health

Recruiting

Comparing Rapid Micro-Induction and Standard Induction of Buprenorphine/Naloxone for Treatment of Opioid Use Disorder

Opioid Use Disorder

Canada
Nasus Pharma

Completed

A Single-Dose, Bioequivalence Study of FMXIN001 4 mg Microspheres Powder

Opioid Overdose

Canada
University of British Columbia

Recruiting

Evaluating Buprenorphine/Naloxone Microdosing vs. Standard Dosing in Emergency Departments

Opioid-use Disorder

Canada
Centre hospitalier de l'Université de Montréal...
Pfizer

Completed

Desvenlafaxine in Opioid-Dependent Patients

Depression | Opioid Dependence | Methadone Treatment

Canada
University of British Columbia
Canadian Institutes of Health Research (CIHR); Providence Healthcare; Innerchange...

Completed

Study to Assess Longer-term Opioid Medication Effectiveness (SALOME) (SALOME)

Heroin Dependence | Opioid Dependence

Canada
Didier Jutras Aswad
Canadian Institutes of Health Research (CIHR)

Completed

A Pragmatic Randomized Control Trial Comparing Models of Care in the Management of Prescription Opioid Misuse (OPTIMA)

Opioid Use Disorder

Canada
BC Centre on Substance Use
Canadian Institutes of Health Research (CIHR)

Not yet recruiting

Evaluating Tetrahydrocannabinol as an Adjunct to Opioid Agonist Therapy (THC-MMT)

Cannabis | Opioid Use Disorder | Fentanyl | Methadone

Canada
Naveen Poonai

Completed

Oral Morphine Versus Ibuprofen

Upper Extremity Fractures | Analgesia Post Fracture

Canada

Clinical Trials on Analgesics, Opioids in Canada

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