Clinical Trials on Anaplastic Glioma of Brain in United States

Total 1603 results

Oliver Jonas, PhD

Recruiting

Implantable Microdevice In Primary Brain Tumors

Glioblastoma | Astrocytoma | Anaplastic Oligodendroglioma | Anaplastic Astrocytoma of Brain | Grade III Glioma | Grade IV Glioma | Grade II Glioma | Oligodendroglioma of Brain

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); Treovir, LLC; American Lebanese Syrian Associated...

Not yet recruiting

HSV G207 With a Single Radiation Dose in Children With Recurrent High-Grade Glioma

Neoplasms | Malignant Glioma of Brain | Glioblastoma Multiforme | High Grade Glioma | Giant Cell Glioblastoma | High-grade Glioma | Anaplastic Astrocytoma of Brain | Anaplastic Glioma

United States
Memorial Sloan Kettering Cancer Center
Columbia University; Genentech, Inc.; University of California, San Francisco

Completed

Hypofractionated Stereotactic Radiotherapy With Bevacizumab in the Treatment of Recurrent Malignant Glioma

Glioblastoma | Brain Cancer | Anaplastic Astrocytoma (AA) | Anaplastic Oligodendroglioma (AO) | MALIGNANT GLIOMA | Anaplastic Oligo-astrocytoma (AOA) | Anaplastic Mixed Gliomas | Malignant Glioma NOS

United States
University of Alabama at Birmingham

Not yet recruiting

Re-Administration of C134 in Patients With Recurrent GBM (C134-HSV-1)

Recurrent Malignant Glioma | Glioblastoma Multiforme of Brain | Anaplastic Astrocytoma of Brain | Gliosarcoma of Brain

United States
Istari Oncology, Inc.
Duke University; Solving Kids' Cancer; The Andrew McDonough B+ Foundation

Completed

Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Children

Glioblastoma | Malignant Glioma | Gliosarcoma | Ependymoma | Medulloblastoma | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Atypical Teratoid/Rhabdoid Tumor of Brain | Pleomorphic Xanthoastrocytoma of Brain | Embryonal Tumor of Brain

United States
Case Comprehensive Cancer Center

Terminated

Ritonavir and Lopinavir in Treating Patients With Progressive or Recurrent High-Grade Glioma

Glioblastoma | Brain Tumor | Gliosarcoma | Anaplastic Astrocytoma | Anaplastic Ependymoma | Anaplastic Oligodendroglioma | Giant Cell Glioblastoma | Mixed Glioma | Brain Stem Glioma

United States
University of Alabama at Birmingham
National Cancer Institute (NCI); Gateway for Cancer Research

Recruiting

Trial of C134 in Patients With Recurrent GBM (C134-HSV-1)

Glioblastoma Multiforme of Brain | Anaplastic Astrocytoma of Brain | Gliosarcoma of Brain

United States
City of Hope Medical Center

Completed

A Pilot Feasibility Study of Oral 5-Fluorocytosine and Genetically-Modified Neural Stem Cells Expressing E.Coli Cytosine Deaminase for Treatment of Recurrent High Grade Gliomas

Recurrent High Grade Glioma | Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Recurrent Adult Brain Tumor | Recurrent Grade III Glioma | Adult Brain Tumor | Recurrent Grade IV Glioma | Adult Anaplastic...

United States
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

Cellular Immunotherapy Study for Brain Cancer (alloCTL)

Glioblastoma Multiforme | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Gliomas | Anaplastic Mixed Glioma | Malignant Meningioma

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Bafetinib in Treating Patients With Recurrent High-Grade Glioma or Brain Metastases

Adult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Recurrent Adult Brain Tumor | Tumors Metastatic to Brain | Adult Anaplastic Oligoastrocytoma

United States
University of Washington
National Cancer Institute (NCI)

Terminated

Aminolevulinic Acid During Surgery in Treating Patients With Malignant Brain Tumors

Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Recurrent Adult Brain Tumor

United States
Dana-Farber Cancer Institute
National Institutes of Health (NIH); Candel Therapeutics, Inc.

Recruiting

A Study of the Treatment of Recurrent Malignant Glioma With rQNestin34.5v.2 (rQNestin)

Glioma | Glioblastoma | Astrocytoma | Malignant Glioma of Brain | Brain Cancer | Brain Tumor | Glioblastoma Multiforme | Ependymoma | Ganglioglioma | Oligodendroglioma | Malignant Astrocytoma | Anaplastic Oligodendroglioma of Brain (Diagnosis) | Mixed Oligo-Astrocytoma | Pylocytic/Pylomyxoid Astrocytoma

United States
National Cancer Institute (NCI)

Completed

Gefitinib and Radiation Therapy in Treating Children With Newly Diagnosed Gliomas

Untreated Childhood Brain Stem Glioma | Untreated Childhood Anaplastic Astrocytoma | Untreated Childhood Anaplastic Oligodendroglioma | Untreated Childhood Giant Cell Glioblastoma | Untreated Childhood Glioblastoma | Untreated Childhood Gliomatosis Cerebri | Untreated Childhood Gliosarcoma | Untreated...

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Feasibility of Intraoperative Microdialysis During Neurosurgery for Central Nervous System Malignancies

Glioblastoma | Anaplastic Astrocytoma | Oligodendroglioma | Diffuse Astrocytoma | Anaplastic Oligodendroglioma | Metastatic Malignant Neoplasm in the Brain | Diffuse Glioma

United States
Weill Medical College of Cornell University

Terminated

Intraarterial Infusion Of Erbitux and Bevacizumab For Relapsed/Refractory Intracranial Glioma In Patients Under 22

Glioblastoma Multiforme | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma | Brain Stem Glioma | Pilomyxoid Astrocytoma | Glioma of Brainstem | Fibrillary Astrocytoma of Brain | Mixed Oligodendroglioma-Astrocytoma

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Multiple Doses of Neural Stem Cell Virotherapy (NSC-CRAd-S-pk7) for the Treatment of Recurrent High-Grade Gliomas

Recurrent Glioblastoma | Recurrent Malignant Glioma | Recurrent WHO Grade III Glioma | Recurrent WHO Grade II Glioma | Recurrent Gliosarcoma | Recurrent Anaplastic Astrocytoma | Recurrent Anaplastic Oligoastrocytoma | Recurrent Anaplastic Oligodendroglioma

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...
Millennium Pharmaceuticals, Inc.

Completed

Alisertib and Fractionated Stereotactic Radiosurgery in Treating Patients With Recurrent High Grade Gliomas

Adult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma | Adult Diffuse Astrocytoma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Adult Oligodendroglioma | Adult Pilocytic Astrocytoma | Adult Pineal Gland Astrocytoma | Recurrent... and other conditions

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Completed

Vaccine Therapy and Sargramostim in Treating Patients With Malignant Glioma

Glioblastoma | Gliosarcoma | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Giant Cell Glioblastoma | Recurrent Brain Neoplasm | Mixed Glioma

United States
Patrick Y. Wen, MD
Massachusetts General Hospital; Dana-Farber Cancer Institute; Brigham and Women... and other collaborators

Terminated

Plerixafor (AMD3100) and Bevacizumab for Recurrent High-Grade Glioma

High Grade Glioma: Glioblastoma (GBM) | High Grade Glioma: Gliosarcoma | Anaplastic Astrocytoma (AA) | Anaplastic Oligodendroglioma (AO) | Mixed Anaplastic Oligoastrocytoma (AOA)

United States
National Cancer Institute (NCI)

Terminated

Sunitinib to Treat Recurrent Brain Cancer

Glioblastoma Multiforme | Malignant Gliomas | Anaplastic Gliomas

United States
City of Hope Medical Center

Completed

Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Glucocorticoids, in Combination With Interleukin-2

Glioblastoma | Brain Tumor | Gliosarcoma | Anaplastic Astrocytoma | Anaplastic Ependymoma | Anaplastic Oligodendroglioma | Giant Cell Glioblastoma | Anaplastic Meningioma | Mixed Glioma | Brain Stem Glioma | Ependymoblastoma | Grade III Meningioma | Meningeal Hemangiopericytoma | Pineal Gland Astrocytoma

United States
OHSU Knight Cancer Institute
Oregon Health and Science University

Completed

Carboplatin, Melphalan, Etoposide Phosphate, Mannitol, and Sodium Thiosulfate in Treating Patients With Previously Treated Brain Tumors

Anaplastic Oligoastrocytoma | Oligoastrocytoma | Anaplastic Oligodendroglioma | Mixed Glioma

United States
M.D. Anderson Cancer Center

Recruiting

Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) Glioblastomas

Glioblastoma | Anaplastic Oligoastrocytoma | Oligoastrocytoma | Oligodendroglioma | Anaplastic Oligodendroglioma | WHO Grade III Glioma | Diffuse Astrocytoma, IDH-Wildtype | WHO Grade II Glioma | Anaplastic Astrocytoma, IDH-Wildtype

United States
Mayo Clinic
National Cancer Institute (NCI)

Active, not recruiting

Fluorine F 18 Fluorodopa-Labeled PET Scan in Planning Surgery and Radiation Therapy in Treating Patients With Newly Diagnosed High- or Low-Grade Malignant Glioma

Adult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma | Adult Diffuse Astrocytoma | Adult Ependymoma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Adult Myxopapillary Ependymoma | Adult Oligodendroglioma | Adult Pilocytic... and other conditions

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Carboxylesterase-Expressing Allogeneic Neural Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade Gliomas

Recurrent Glioblastoma | Recurrent Malignant Glioma | Recurrent WHO Grade III Glioma | Recurrent Gliosarcoma | Recurrent Anaplastic Astrocytoma | Recurrent Anaplastic Oligoastrocytoma | Recurrent Anaplastic Oligodendroglioma

United States
Children's Hospital Medical Center, Cincinnati
Novartis

Completed

A Study of Ribociclib and Everolimus Following Radiation Therapy in Children With Newly Diagnosed Non-biopsied Diffuse Pontine Gliomas (DIPG) and RB+ Biopsied DIPG and High Grade Gliomas (HGG)

Glioblastoma | Malignant Glioma of Brain | High Grade Glioma | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma | Brainstem Glioma | Bithalamic High Grade Glioma

United States
Erik Mittra
National Cancer Institute (NCI)

Terminated

18F-FDOPA PET/CT or PET/MRI in Measuring Tumors in Patients With Newly-Diagnosed or Recurrent Gliomas

Untreated Childhood Brain Stem Glioma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma | Adult Diffuse Astrocytoma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Adult Oligodendroglioma | Adult Pilocytic Astrocytoma | Adult Pineal Gland Astrocytoma and other conditions

United States
Dartmouth-Hitchcock Medical Center

Recruiting

Evaluating the Expression Levels of MicroRNA-10b in Patients With Gliomas

Glioblastoma | Astrocytoma | Brain Cancer | Anaplastic Oligoastrocytoma | Oligoastrocytoma | Anaplastic Astrocytoma | Oligodendroglioma | Brain Tumors | Anaplastic Oligodendroglioma

United States
Andrew B Lassman, MD
Pfizer; AEterna Zentaris

Completed

Perifosine and Torisel (Temsirolimus) for Recurrent/Progressive Malignant Gliomas

Glioblastoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Brain Tumor, Recurrent | Mixed Glioma

United States
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Terminated

3T MRI Biomarkers of Glioma Treatment Response

Adult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
James Elder

Completed

Carboplatin in Treating Patients With Recurrent High-Grade Gliomas

Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Recurrent Adult Brain Tumor

United States
National Cancer Institute (NCI)

Completed

Aflibercept, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed or Recurrent Glioblastoma Multiforme, Gliosarcoma, or Other Malignant Glioma

Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Recurrent Adult Brain Tumor

United States
National Cancer Institute (NCI)

Active, not recruiting

Lapatinib Ditosylate Before Surgery in Treating Patients With Recurrent High-Grade Glioma

Gliosarcoma | Recurrent Glioblastoma | Anaplastic Astrocytoma | Anaplastic Ependymoma | Anaplastic Oligodendroglioma | Mixed Glioma | Recurrent Adult Brain Neoplasm

United States
National Cancer Institute (NCI)

Completed

Veliparib, Radiation Therapy, and Temozolomide in Treating Younger Patients With Newly Diagnosed Diffuse Pontine Gliomas

Glioblastoma | Gliosarcoma | Anaplastic Astrocytoma | Untreated Childhood Brain Stem Glioma | Giant Cell Glioblastoma | Untreated Childhood Anaplastic Astrocytoma | Untreated Childhood Giant Cell Glioblastoma | Untreated Childhood Glioblastoma | Untreated Childhood Gliosarcoma | Brain Stem Glioma | Untreated... and other conditions

United States
National Cancer Institute (NCI)

Terminated

RO4929097and Bevacizumab in Treating Patients With Progressive or Recurrent Malignant Glioma

Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
National Cancer Institute (NCI)

Terminated

High-Dose Vorinostat and Fractionated Stereotactic Body Radiation Therapy in Treating Patients With Recurrent Glioma

Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Recurrent Adult Brain Neoplasm

United States
National Cancer Institute (NCI)

Completed

VEGF Trap in Treating Patients With Recurrent Malignant Gliomas That Did Not Respond to Temozolomide

Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); Roswell Park Cancer Institute; American Lebanese...

Recruiting

A Pilot Study of SurVaxM in Children Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine Glioma

Glioblastoma Multiforme | Ependymoma | Medulloblastoma | Anaplastic Astrocytoma | Anaplastic Ependymoma | Anaplastic Oligodendroglioma | Diffuse Intrinsic Pontine Glioma | High-grade Astrocytoma NOS

United States, Canada
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Terminated

Erlotinib Hydrochloride and Isotretinoin in Treating Patients With Recurrent Malignant Glioma

Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Diffuse Astrocytoma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Adult Oligodendroglioma | Recurrent Adult Brain Tumor

United States
National Cancer Institute (NCI)

Completed

AZD8055 for Adults With Recurrent Gliomas

Glioblastoma Multiforme | Malignant Glioma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Brainstem Glioma

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Genetically Modified Neural Stem Cells, Flucytosine, and Leucovorin for Treating Patients With Recurrent High-Grade Gliomas

Anaplastic Oligoastrocytoma | Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Terminated

Determining Dose of Regadenoson Most Likely to Transiently Alter the Integrity of the Blood-Brain Barrier in Patients With High Grade Gliomas

Glioblastoma | High Grade Glioma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma

United States
St. Jude Children's Research Hospital
Novartis Pharmaceuticals

Active, not recruiting

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

Glioma | Neoplasms | Glioblastoma | Neoplasms, Neuroepithelial | Central Nervous System Neoplasms | Brain Cancer | Brain Tumor | Ependymoma | Medulloblastoma | Anaplastic Astrocytoma | Anaplastic Ganglioglioma | Anaplastic Ependymoma | Anaplastic Oligodendroglioma | Pineoblastoma | Recurrent Medulloblastoma | CNS Tumor | Pediatric... and other conditions

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...

Completed

Phase I Study of Mebendazole Therapy for Recurrent/Progressive Pediatric Brain Tumors

Glioblastoma | Malignant Glioma | Medulloblastoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Astrocytoma, Grade III | Brain Stem Neoplasms, Malignant | Oligodendroblastoma

United States
M.D. Anderson Cancer Center

Completed

6-TG, Capecitabine and Celecoxib Plus TMZ or CCNU for Anaplastic Glioma Patients

Brain Cancer | Glioblastoma Multiforme | Anaplastic Glioma of Brain

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Viral Therapy in Treating Patients With Recurrent Glioblastoma Multiforme

Recurrent Glioblastoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Mixed Glioma

United States
National Cancer Institute (NCI)

Completed

Sorafenib in Treating Patients With Recurrent or Progressive Malignant Glioma

Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
Northwestern University
National Cancer Institute (NCI)

Completed

Neural Stem Cell Based Virotherapy of Newly Diagnosed Malignant Glioma

Glioma | Brain Cancer | Glioblastoma Multiforme | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Astrocytoma, Grade III | Astrocytoma, Grade IV

United States
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Pediatric Patients With BRAF V600 Mutation Positive LGG or Relapsed or Refractory HGG Tumors

Glioblastoma | Astrocytoma | Anaplastic Astrocytoma | Anaplastic Ganglioglioma | Anaplastic Pleomorphic Xanthoastrocytoma | Ganglioglioma | Pleomorphic Xanthoastrocytoma | Diffuse Astrocytoma | Anaplastic Oligodendroglioma | Pilocytic Astrocytoma | Gangliocytoma | Central Neurocytoma | Oligodendroglioma, Childhood and other conditions

United States, Italy, Japan, Germany, Spain, France, Canada, Australia, Brazil, Israel, Russian Federation, Argentina, United Kingdom, Finland, Belgium, Denmark, Czechia, Sweden, Switzerland, Netherlands
National Cancer Institute (NCI)

Terminated

(11C)dLop as a Marker of P-Glycoprotein Function in Patients With Gliomas

Glioblastoma Multiforme | Oligoastrocytoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Low Grade Glioma

United States

Clinical Trials on Anaplastic Glioma of Brain in United States

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