Clinical Trials on Ankle Injuries and Disorders

Total 166202 results

Icahn School of Medicine at Mount Sinai

Completed

Vagus Nerve Stimulation as Treatment for Long Covid

Chronic Fatigue Syndrome | Long COVID

United States
Orchard Therapeutics
Ospedale San Raffaele

Active, not recruiting

A Safety and Efficacy Study of Cryopreserved OTL-200 for Treatment of Metachromatic Leukodystrophy (MLD)

Lysosomal Storage Disease | Metachromatic Leukodystrophy

Italy
University of Colorado, Denver
Massachusetts General Hospital; Beta Bionics, Inc.

Completed

Feasibility of Closed-loop Automated Insulin Delivery System by Primary Care & Endocrinology, in Person & Via Telehealth

Diabetes Mellitus, Type 1 | Type 1 Diabetes | Diabetes type1 | Type 1 Diabetes Mellitus | Autoimmune Diabetes | Diabetes Mellitus, Insulin-Dependent | Juvenile-Onset Diabetes | Diabetes, Autoimmune | Insulin-Dependent Diabetes Mellitus 1 | Diabetes Mellitus, Insulin-Dependent, 1 | Diabetes Mellitus, Brittle | Diabetes Mellitus, Juvenile-Onset and other conditions

United States
Université de Sherbrooke
Hotel Dieu Hospital

Completed

Telerehabilitation for Post COVID-19 Condition (Telecovie)

Chronic Fatigue Syndrome | Long COVID

Canada
Orchard Therapeutics
Ospedale San Raffaele

Active, not recruiting

Gene Therapy for Metachromatic Leukodystrophy (MLD)

Lysosomal Storage Disease | Metachromatic Leukodystrophy

Italy
Shire

Completed

Metazym for the Treatment of Patients With Late Infantile Metachromatic Leukodystrophy (MLD)

Metachromatic Leukodystrophy (MLD)

Denmark
Shire

Completed

Long-term Metazym Treatment of Patients With Late Infantile Metachromatic Leukodystrophy (MLD)

Late Infantile Metachromatic Leukodystrophy

Denmark
University of Minnesota
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Terminated

Synergistic Enteral Regimen for Treatment of the Gangliosidoses (Syner-G)

Tay-Sachs Disease | Sandhoff Disease | GM1 Gangliosidoses | GM2 Gangliosidoses

United States
University of Pennsylvania
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other collaborators

Completed

Plasma Exchange and Glucocorticoids for Treatment of Anti-Neutrophil Cytoplasm Antibody (ANCA) - Associated Vasculitis (PEXIVAS)

Microscopic Polyangiitis (MPA) | Granulomatosis With Polyangiitis (Wegener's) (GPA)

United States, Belgium, France, United Kingdom, Denmark, Canada, Japan, Australia, New Zealand, Sweden, Czechia, Italy, Greece, Mexico, Norway
Assistance Publique - Hôpitaux de Paris
European Leukodystrophy Association

Completed

Imaging Study of the White Matter Lesions in Children With Metachromatic Leucodystrophy (HCIT-MLD)

Late Infantile Metachromatic Leukodystrophy

France
University of Minnesota
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Completed

Gene Therapy for Tay-Sachs Disease

Tay Sachs Disease | Sandhoff Disease | Late Onset Tay Sachs Disease

United States
University of Nebraska
National Cancer Institute (NCI)

Completed

Combination Chemotherapy & Lenalidomide in Newly Diagnosed Stage II-IV Peripheral T-cell Non-Hodgkin's Lymphoma

Anaplastic Large Cell Lymphoma, ALK-Positive | Hepatosplenic T-Cell Lymphoma | Peripheral T-Cell Lymphoma, Not Otherwise Specified | Anaplastic Large Cell Lymphoma, ALK-Negative | Stage II Angioimmunoblastic T-cell Lymphoma | Stage II Enteropathy-Associated T-Cell Lymphoma | Stage III Angioimmunoblastic... and other conditions

United States
Medical University of Warsaw

Completed

Heart Rhythm After Intravenous Methylprednisolone Administration

Heart Failure | Hypertension | Graves Ophthalmopathy | Graves Disease | Blood Pressure | Heart Rhythm Disorder
M.D. Anderson Cancer Center

Active, not recruiting

Modified Immune Cells (AFM13-NK) and A Monoclonal Antibody (AFM13) in Treating Patients With Recurrent or Refractory CD30 Positive Hodgkin or Non-Hodgkin Lymphomas

Refractory B-Cell Non-Hodgkin Lymphoma | Recurrent B-Cell Non-Hodgkin Lymphoma | Recurrent Mycosis Fungoides | Refractory Mycosis Fungoides | Recurrent Classic Hodgkin Lymphoma | Refractory Classic Hodgkin Lymphoma | Refractory Anaplastic Large Cell Lymphoma | Recurrent Anaplastic Large Cell Lymphoma and other conditions

United States
Roswell Park Cancer Institute
Lumeda,Inc.

Active, not recruiting

Light Dosimetry for Photodynamic Therapy With Porfimer Sodium in Treating Participants With Malignant Mesothelioma or Non-Small Cell Lung Cancer With Pleural Disease Undergoing Surgery

Malignant Mesothelioma | Non-Small Cell Lung Carcinoma | Pleural Disorder

United States
National Cancer Institute (NCI)

Terminated

PXD101 and 17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Metastatic or Unresectable Solid Tumors or Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
National Cancer Institute (NCI)

Completed

Ipilimumab After Allogeneic Stem Cell Transplant in Treating Patients With Persistent or Progressive Cancer

Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Recurrent Adult Acute Myeloid Leukemia | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Immunoblastic Large Cell Lymphoma and other conditions

United States
Guillermo Ceballos Reyes
Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado

Recruiting

Effects of Cacao FLAvonoids in LOng Covid Patients (FLALOC) (FLALOC)

Fatigue Syndrome, Chronic | Long Covid19

Mexico
Nanfang Hospital of Southern Medical University

Recruiting

Decitabine and HQP1351-based Chemotherapy Regimen for the Treatment Advanced CML (Case-Only)

Chronic Myeloid Leukemia in Myeloid Blast Crisis | Chronic Myeloid Leukaemia Transformation | Chronic Myeloid Leukemia - Accelerated Phase | Chronic Myeloid Leukemia in Lymphoid Blast Crisis

China
Seoul National University Boramae Hospital

Completed

Prospective Cohort Study of Association of Insulin Resistance/Steatosis With Hepatic Fibrosis in CHB and NAFLD

Fatty Liver | Chronic Hepatitis B | Hepatic Fibrosis

Korea, Republic of
Shire

Completed

Multicenter Study of HGT-1110 Administered Intrathecally in Children With Metachromatic Leukodystrophy (MLD) (IDEAMLD)

Metachromatic Leukodystrophy (MLD)

Australia, Denmark, Japan, France, Germany
Shire

Terminated

Open-Label Extension Study of Recombinant Human Arylsulfatase A (HGT-1111) in Late Infantile MLD

Late Infantile Metachromatic Leukodystrophy

Denmark
Haukeland University Hospital

Unknown

Switching From Insulin to Sulfonylurea in Diabetes Associated With Variants in MODY Genes (SUtoChildT1D)

Insulin-dependent Diabetes Mellitus | Maturity-Onset Diabetes of the Young, Type 3 | Maturity Onset Diabetes of the Young, Type 1 | Childhood Diabetes Mellitus

Norway
Assistance Publique - Hôpitaux de Paris

Completed

Biomarkers in Autosomal Dominant Cerebellar Ataxia (BIOSCA)

Spinocerebellar Ataxia Type 1 | Spinocerebellar Ataxia Type 2 | Spinocerebellar Ataxia, Autosomal Recessive 3 | Episodic Ataxia, Type 7

France
Genzyme, a Sanofi Company

Completed

Safety and Efficacy of Recombinant Human Acid Alpha-Glucosidase in the Treatment of Classical Infantile Pompe Disease

Glycogen Storage Disease Type II | Acid Maltase Deficiency Disease | Glycogenosis 2 | Pompe Disease

United States
Children's National Research Institute

Completed

Prevalence of Proteinuria and Chronic Kidney Disease in Pediatric HIV-Infected Patients

HIV Infections | Chronic Kidney Failure | AIDS-Associated Nephropathy

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

CD19 CAR T Cells for B Cell Malignancies After Allogeneic Transplant

Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Immunoblastic Large Cell Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Adult Acute Lymphoblastic Leukemia | Refractory Chronic Lymphocytic Leukemia | Philadelphia Chromosome Positive Adult Precursor Acute Lymphoblastic Leukemia and other conditions

United States
National Cancer Institute (NCI)

Terminated

Combination Chemotherapy and Rituximab in Treating Young Patients With Recurrent or Refractory Non-Hodgkin's Lymphoma or Acute Lymphoblastic Leukemia

Recurrent Childhood Acute Lymphoblastic Leukemia | B-cell Childhood Acute Lymphoblastic Leukemia | Childhood Diffuse Large Cell Lymphoma | Childhood Immunoblastic Large Cell Lymphoma | Recurrent Childhood Large Cell Lymphoma | Recurrent Childhood Lymphoblastic Lymphoma | Recurrent Childhood Small... and other conditions

United States
OHSU Knight Cancer Institute
National Cancer Institute (NCI); Oregon Health and Science University

Recruiting

Identifying and Caring for Individuals With Inherited Cancer Syndrome

Malignant Solid Neoplasm | Lynch Syndrome | Hematopoietic and Lymphoid System Neoplasm | Breast Ductal Carcinoma In Situ | Hereditary Neoplastic Syndrome | BRCA1/2-Associated Hereditary Breast and Ovarian Cancer Syndrome

United States
ReVivo Medical, Corp.
The Cleveland Clinic; Albany Medical College; IGEA

Recruiting

CEM-Plate and CEM-Cage First-In-Human Use Efficacy Study

Neck Pain | Spondylosis | Spondylosis With Myelopathy | Spondylosis With Radiculopathy | Spondylosis With Radiculopathy Cervical Region | Intervertebral Disc Disorder Cervical

United States
Institut Paoli-Calmettes

Recruiting

Pancreatic Radiofrequency Under High Echo-endoscopy in the Management of Pancreatic Neuroendocrine Tumors (RFANET)

Neuroendocrine Tumor Grade 1 | Neuroendocrine Tumor of Pancreas (Disorder)

France
Oneness Biotech Co., Ltd.

Completed

A Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of Inhaled MBS-COV (SNS812) in Healthy Participants

Disease Caused by Severe Acute Respiratory Syndrome Coronavirus 2 (Disorder)

United States
Novo Nordisk A/S

Completed

Investigation of Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Multiple Doses of Somapacitan in Subjects With Mild and Moderate Degrees of Hepatic Impairment Compared to Subjects With Normal Hepatic Function.

Growth Hormone Disorder | Growth Hormone Deficiency in Children | Adult Growth Hormone Deficiency

Slovakia
Third Affiliated Hospital, Sun Yat-Sen University

Recruiting

Efficacy and Safety of Avatrombopag for Treating TCP in HBV-ACLF Patients Receiving ALSS Treatment

Acute-On-Chronic Liver Failure | Hepatitis B, Chronic | Thrombocytopenia

China
Children's Oncology Group
National Cancer Institute (NCI)

Recruiting

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

Melanoma | Neuroblastoma | Pancreatic Ductal Adenocarcinoma | Refractory Malignant Solid Neoplasm | Endometrial Carcinoma | Recurrent Ewing Sarcoma | Recurrent Hepatoblastoma | Recurrent Malignant Solid Neoplasm | Recurrent Non-Hodgkin Lymphoma | Recurrent Osteosarcoma | Refractory Ewing Sarcoma | Refractory... and other conditions

United States
Mayo Clinic

Recruiting

Quality of Life After Treatment for Bladder Cancer: The Bladder Cancer Survivorship Study

Stage 0a Bladder Cancer AJCC v8 | Stage 0is Bladder Cancer AJCC v8 | Stage I Bladder Cancer AJCC v8 | Stage IIIA Bladder Cancer AJCC v8 | Stage II Bladder Cancer AJCC v8

United States
Marco Capogrosso
Roche-Genentech

Not yet recruiting

Spinal Cord Stimulation for the Treatment of Motor Deficits in People With Spinal Muscular Atrophy - Upper Limb

Spinal Muscular Atrophy | Spinal Muscular Atrophy Type 3 | SMA | Spinal Muscular Atrophy Type II | Spinal Muscular Atrophy 4

United States
Bahçeşehir University

Not yet recruiting

Public AttitudesTowards SMA and DMD Awareness, Newborn and Carrier Screening and Physiotherapy Practices

Duchenne Muscular Dystrophy | Spinal Muscular Atrophy | Healthy Individuals
John Paul II Hospital, Krakow

Recruiting

Simultaneous Cardiac Surgery and Micronet-covered Stent Carotid Revascularization in High Perioperative Stroke Risk Patients (SIM-GUARD)

Myocardial Infarction | Coronary Artery Disease | Carotid Stenosis | Valvular Heart Disease | Pulmonary Edema With Heart Failure

Poland
University of Alabama at Birmingham

Recruiting

Study of Carboplatin and Mirvetuximab Soravtansine in First-Line Treatment of Patients Receiving Neoadjuvant Chemotherapy With Advanced-Stage Ovarian, Fallopian Tube or Primary Peritoneal Cancer

Ovarian Cancer | Primary Peritoneal Cancer | Fallopian Tube

United States
University Hospital, Strasbourg, France

Recruiting

COhort for Bardet-Bield Syndrome and Alström Syndrome for Translational Research Monocentric Interventional Study (COBBALT)

Bardet-Biedl Syndrome | Alström Syndrome

France
Carl Allen
Baylor College of Medicine; Genentech, Inc.; North American Consortium for Histiocytosis

Recruiting

Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders (NACHO-COBI)

Histiocytic Sarcoma | Juvenile Xanthogranuloma | Histiocytic Disorders, Malignant | Erdheim-Chester Disease | Langerhan's Cell Histiocytosis | Rosai Dorfman Disease | Neuro-Degenerative Disease

United States
Scholar Rock, Inc.

Active, not recruiting

Efficacy and Safety of Apitegromab in Patients With Later-Onset Spinal Muscular Atrophy Treated With Nusinersen or Risdiplam (SAPPHIRE)

Neuromuscular Diseases | Neuromuscular Manifestations | Atrophy | Muscular Atrophy | Spinal Muscular Atrophy | Muscular Atrophy, Spinal | Spinal Muscular Atrophy Type 3 | SMA | Spinal Muscular Atrophy Type 2 | Anti-myostatin

United States, Germany, Belgium, Spain, United Kingdom, Netherlands, France, Italy, Poland
Corcept Therapeutics
Gynecologic Oncology Group

Active, not recruiting

Relacorilant in Combination With Nab-Paclitaxel in Advanced, Platinum-Resistant, High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian-Tube Cancer

Fallopian Tube Neoplasms | Peritoneal Neoplasms | Ovarian Neoplasm

United States, Argentina, Australia, Belgium, Brazil, Canada, France, Hungary, Israel, Italy, Korea, Republic of, Poland, Spain, United Kingdom
Johns Hopkins University
Rush University Medical Center; University of California, San Francisco; amfAR...

Completed

COVID-19 Recovery Study: Symptoms and Biomarkers of Long COVID-19 in People Living With and Without HIV

HIV | Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2)

United States
Kresten Krarup Keller
Aarhus University Hospital

Active, not recruiting

Improved Diagnostics and Monitoring of Polymyalgia Rheumatica

Giant Cell Arteritis | Polymyalgia Rheumatica | Adrenal Insufficiency

Denmark
Dermatology Specialties Limited Partnership

Completed

Dose-Ranging Efficacy and Safety Study of Topical Rapamycin Cream for Facial Angiofibroma Associated With Tuberous Sclerosis Complex

Tuberous Sclerosis | Facial Angiofibroma

United States, Taiwan, Serbia, Spain, Australia, Czechia, Hungary, New Zealand, Slovakia
HaEmek Medical Center, Israel

Terminated

Liver and the Spleen Stifness in Adult Patients With Gaucher's Disease Using Ultrasound Shear Wave Elastography

Liver Fibrosis | Gaucher Disease | Spleen; Fibrosis

Israel
Nationwide Children's Hospital
Novartis

Active, not recruiting

Body Weight Support Harness System in Spinal Muscular Atrophy

Spinal Muscular Atrophy Type II | Spinal Muscular Atrophy Type I

United States
Seung Up Kim

Active, not recruiting

Effects of Pioglitazone and Evogliptin on Hepatic Fibrosis in Patients With Chronic Hepatitis B With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Hepatitis B, Chronic | Fibrosis, Liver

Korea, Republic of

Clinical Trials on Ankle Injuries and Disorders

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