Clinical Trials on Anti-HLA Antibody

Total 682 results

Anhui Provincial Hospital

Not yet recruiting

The Efficacy and Safety of Desensitation Regimen for Patients With High Titers of Anti-HLA Antibodies Prior to Allo-HSCT

High Titers of Anti-HLA Antibody (MFI ≥5000)

China
Assistance Publique - Hôpitaux de Paris
Etablissement Français du Sang (Nouvelle Aquitaine)

Recruiting

Obstetrical History and Anti-HLA Antibodies Level (OBS-HLA)

Blood Donors | Anti-HLA Antibody

France
Databean
Octapharma

Terminated

A Prospective, Global, Multi-center, Treatment Registry Study of Intravenous Immunoglobulin Maintenance Therapy in Alloantibody Positive Renal Allograft Recipients (DSA)

Renal Transplant Recipients With Anti-HLA Antibodies

United States
Northwestern University

Terminated

An In-vitro Standardization of B Cell Elispot Assays

Transplant Sensitization | Panel Reactive Antibody | Sensitization to HLA Antigens

United States
Hannover Medical School

Recruiting

Monitoring of Donor-specific Antibodies After Treatment With Immunoglobulins, Plasmapheresis and Rituximab in Lung Transplantation

Lung Transplantation | Donor-specific Anti-human Leukocyte Antigen(HLA) Antibodies

Germany
Nanjing University School of Medicine

Completed

MMF Versus CTX in the Induction Treatment of ANCA Associated Vasculitis

Vasculitis | Anti-Neutrophil Cytoplasmic Antibody

China
National Cancer Institute (NCI)

Completed

HPV Vaccine Effectiveness in Partially Vaccinated Girls in Uganda

HPV16 Anitbody Levels Post Vaccination | HPV18 Antibody Levels Post Vaccination

Uganda
Klemens Budde
Charite University, Berlin, Germany; Dr. med. univ. L. J. Lehner; ERA-EDTA; DESCARTES... and other collaborators

Not yet recruiting

European Transplant Registry of Senior Renal Transplant Recipients on Advagraf (SENIOR)

Infections | Quality of Life | Death | Cardiovascular Risk Factors | Graft Failure | Bone Disease | Post Transplant Diabetes Mellitus | Acute Rejection of Renal Transplant | HLA Antibody Production | Non-HLA Antibody Production
Medical University of Graz

Terminated

Detection and Characterization of Anti-SARS-CoV-2 Salivary Antibodies After COVID-19 Booster Vaccines (CoVVacBoost)

Anti-SARS-CoV-2 Antibody Response

Austria
Amgen

Completed

A Study in Healthy Volunteers to Evaluate the Pharmacokinetic Food Effect and Cardiac Safety of CCX168

Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis

United States
Amgen

Completed

A Study to Assess the Mass Balance Recovery (Absorption, Distribution, Metabolism and Excretion) of [14C]CCX168 in Healthy Participants

Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis

United States
Amgen

Completed

A Study of CCX168 in Japanese and Caucasian Healthy Adult Males

Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis

Japan
University of Cincinnati
Millennium Pharmaceuticals, Inc.

Completed

Desensitization in Kidney Transplantation

HLA Sensitization

United States
Assistance Publique - Hôpitaux de Paris
URC-CIC Paris Descartes Necker Cochin

Not yet recruiting

Study of Salvage Therapy to Treat Patients With Granulomatosis With Polyangiitis (SATELITE)

Granulomatosis With Polyangiitis | Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis

France
Amgen

Recruiting

A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis

Antineutrophil Cytoplasmic Antibody-associated Vasculitis

United States
Amgen

Completed

A Study in Healthy Volunteers to Evaluate the Drug-Drug Interaction Potential of CCX168 With Concomitant Medications

Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis

United States
Mårten Segelmark
Hansa Biopharma AB

Completed

Open-Label Phase II Study to Evaluate the Efficacy and Safety of IdeS in Anti-GBM Disease (GOOD-IDES-01)

Anti-Glomerular Basement Membrane Antibody Disease

Austria, Czechia, Denmark, France, Sweden
Staidson (Beijing) Biopharmaceuticals Co., Ltd

Completed

The Safety and Tolerability of STSA-1002 Following Subcutaneous Injection in Healthy Subjects

Antineutrophil Cytoplasmic Antibody Associated Vasculitis

United States
University of North Carolina, Chapel Hill
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Withdrawn

Targeting Complement Activation in Antineutrophil Cytoplasmic Autoantibodies (ANCA)-Vasculitis - Eculizumab

Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis

United States
University of North Carolina, Chapel Hill
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Withdrawn

Retinoids in ANCA Small Vessel Vasculitis: Silencing Autoantigens

Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis

United States
Life Technologies Corporation

Completed

Clinical Protocol SeCore, uTYPE and 3500 Dx System

Human Leukocyte Antigens (HLA)
University Hospital, Brest

Recruiting

Biocollection of Patients With ANCA Associated Vasculitis (ANCA)

ANCA-associated Vasculitis

France
Nantes University Hospital
INSERM UMRS-1064

Completed

MICRO-RNAs OF NEUTROPHILS IN RENAL ANTINEUTROPHIL CYTOPLASMIS ANTIBODY (ANCA) -ASSOCIATED VASCULITIS (MINERVA)

ANCA-associated Vasculitis

France
Hillel Yaffe Medical Center

Unknown

Differing Levels of Positive Anti-Neutrophil Cytoplasm Antibody (ANCA) Test and Their Correlation With Vasculitis or Malignancy or Chronic Inflammation

Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis

Israel
University Hospital, Brest

Completed

NGS for HLA Typing of Donors and récipients oh Hematopoietic Stem Cells (NGS HLA)

Next Generation Sequencing for HLA Typing

France
University Hospital, Strasbourg, France

Recruiting

Pediatric ANCA Associated-vasculitis (PediANCA)

ANCA-Associated Vasculitis

France
Xiangya Hospital of Central South University
The Third Xiangya Hospital of Central South University; Hunan Provincial People... and other collaborators

Recruiting

Multicenter Cohort Study of AAV in Hunan of China

ANCA Associated Vasculitis

China
Chinese PLA General Hospital

Recruiting

The Clinical Trial of Chidamide+Decitabine+Camrelizumab Versus Decitabine+Camrelizumab in Anti-PD-1 Antibody Resistant Patients With Classical Hodgkin Lymphoma.

Hodgkin Lymphoma | Anti-PD-1 Antibody Resistant

China
National Institute of Allergy and Infectious Diseases...
Immune Tolerance Network (ITN)

Terminated

Defining Immune Tolerance in ANCA-associated Vasculitis (AAV) (AAV)

ANCA-Associated Vasculitis

United Kingdom
Zhi-Hong Liu, M.D.

Terminated

The Clinical Efficacy of DFPP in Patients With AAGN

Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis

China
Central Hospital, Nancy, France

Active, not recruiting

Anti-HLA Immunization And Immunosuppressive Therapy Management In Kidney Transplant Patients Returning to Dialysis

Kidney Transplantation | Dialysis | Immunosuppressive Agents | HLA Sensitization

France
Grifols Therapeutics LLC

Completed

Anti-Hepatitis A Virus, Pharmacokinetics, and Safety of Immune Globulin (Human) (GamaSTAN)

Anti-Hepatitis A Antibody Levels in Heathy Subjects

United States
Chinese SLE Treatment And Research Group
The First Affiliated Hospital of Anhui Medical University; Shanghai Zhongshan... and other collaborators

Recruiting

Comparison of the Efficacy of Leflunomide and Azathioprine for the Maintenance Therapy of ANCA Associated Vasculitis (LEFAZAREM)

ANCA Associated Vasculitis | Maintenance Therapy

China
Novartis Pharmaceuticals

Not yet recruiting

Iptacopan in Patients With ANCA Associated Vasculitis

Anti-Neutrophil Cytoplasm Antibodies (ANCA) Associated Vasculitis
Massachusetts General Hospital

Terminated

Maintenance of ANCA Vasculitis Remission by Intermittent Rituximab Dosing (MAINTANCAVAS)

Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis

United States
University Hospital, Brest

Not yet recruiting

Occupational and Environmental Origins of ANCA Vasculitis: Contribution of Data From the National Network for Vigilance and Prevention of Occupational Pathologies (RNV3P) (ANCAPRO)

Occupational Diseases | ANCA Associated Vasculitis | Environmental Exposure

France
NovelMed Therapeutics

Not yet recruiting

Study of NM8074 in Patients With Anti-Neutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis (AAV)

Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Assistance Publique Hopitaux De Marseille

Recruiting

Comparison of ANCA and Anti-GBM Auto-antibodies Removal Kinetics Between Plasma Exchanges and Immunoadsorption in Patients With ANCA-associated Vasculitis or Anti-GBM Disease (CINEVAS)

Kidney Failure, Acute

France
Sun Yat-sen University

Recruiting

Locoregional Therapy Combined With Bevacizumab and PD1/L1 Inhibitor in Advanced Hepatocellular Carcinoma

Advanced Hepatocellular Carcinoma | Bevacizumab | Anti-PD1/PDL1 Antibody

China
University Hospital Birmingham NHS Foundation Trust
Merck Sharp & Dohme LLC

Recruiting

Subclinical Cytomegalovirus Reactivation in Acute ANCA-associated Vasculitis (REACTIVAS)

ANCA Associated Vasculitis

United Kingdom
University Hospital, Lille
Takeda; Laboratoire français de Fractionnement et de Biotechnologies; VitalAire; French Healthcare network for rare immune and hematological disorders (MARIH)

Not yet recruiting

SPAD in Adult Patients (DETECT)

Specific Antibody Deficiency | Predominantly Antibody Deficiencies
Staidson (Beijing) Biopharmaceuticals Co., Ltd

Recruiting

Efficacy and Safety of Substitution of Glucocorticoid for BDB-001 Injection in Patients With Anti-neutrophil Cytoplasmic Antibody(ANCA)-Associated Vasculitis

ANCA-associated Vasculitis

China
Peking Union Medical College Hospital

Recruiting

Anlotinib Plus Anti-PD-1 Antibody AK105 for Advanced Pancreatic Cancer

Anlotinib | Anti-PD-1 Antibody | Advanced Pancreatic Cancer

China
ChemoCentryx

Completed

Clinical Trial to Evaluate Safety and Efficacy of CCX168 in ANCA-Associated Vasculitis

ANCA-associated Vasculitis

United States, Canada
West China Hospital
First Affiliated Hospital of Chongqing Medical University; Sichuan Cancer Hospital... and other collaborators

Recruiting

Sintilimab Plus Hypofractionated Radiotherapy for MSI-H/dMMR Rectal Cancer

Rectal Cancer | Radiotherapy | Anti-PD-1 Antibody | MSI-H | Mmr Deficiency

China
Shanghai Zhongshan Hospital

Completed

Effect of Tofacitinib in Treating ANCA-associated Vasculitis

Drug Use | ANCA Associated Vasculitis | JAK-STAT Pathway Deregulation

China
Chinese SLE Treatment And Research Group

Recruiting

Efficacy and Safety for Telitacicept in the Remission Maintenance Treatment of ANCA-associated Vasculitis (TTCAZAREM)

ANCA-associated Vasculitis | Maintenance Therapy

China
Assistance Publique - Hôpitaux de Paris
Roche Pharma AG

Completed

Comparison Between a Long Term and a Conventional Maintenance Treatment With Rituximab (MAINRITSAN3)

ANCA-associated Vasculitides

France
Vifor Fresenius Medical Care Renal Pharma

Recruiting

Avacostar - (PASS) (Avacostar)

ANCA-associated Vasculitis

United Kingdom, Germany
Sun Yat-sen University
Second Affiliated Hospital of Guangzhou Medical University

Completed

Lenvatinib Combined Anti-PD1 Antibody for the Advanced Hepatocellular Carcinoma

Liver Diseases | Hepatocellular Carcinoma | Anti-PD1 Antibody

China

Clinical Trials on Anti-HLA Antibody

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