Clinical Trials on Anti-biotic Resistance

Total 5913 results

University Hospital, Grenoble

Unknown

CPAP Effect on Blood Pressure and Arterial Stiffness in Obstructive Sleep Apnea Patients With Resistant Hypertension (POP-ART)

Obstructive Sleep Apnea | Hypertension, Resistant to Conventional Therapy

France
Atreca, Inc.

Terminated

A Phase 1b Trial of ATRC-101 in Adults With Advanced Solid Malignancies

Melanoma | Breast Cancer | Hepatocellular Carcinoma | Colorectal Cancer | Ovarian Cancer | Non-Small Cell Lung Cancer | Triple Negative Breast Cancer | Head and Neck Squamous Cell Carcinoma | Esophageal Squamous Cell Carcinoma | Urothelial Carcinoma | Acral Lentiginous Melanoma | Platinum-Resistant Fallopian... and other conditions

United States
Peter Merkel
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other collaborators

Recruiting

Clinical Transcriptomics in Systemic Vasculitis (CUTIS) (CUTIS)

Vasculitis | Eosinophilic Granulomatosis With Polyangiitis (EGPA) | Cryoglobulinemic Vasculitis (CV) | Drug-induced Vasculitis | IgA Vasculitis | Isolated Cutaneous Vasculitis | Granulomatosis With Polyangiitis (GPA) | Microscopic Polyangiitis (MPA) | Polyarteritis Nodosa (PAN) | Urticarial Vasculitis

United States, Canada
Health Service Executive, Ireland

Recruiting

Dundrum Forensic Redevelopment Evaluation Study: D-FOREST Study. (D-FOREST)

Personality Disorders | Cardiovascular Diseases | Obesity | Schizophrenia | Frailty | Recovery | Psychosis | Violence | Type II Diabetes | Treatment-resistant Schizophrenia | Forensic Psychiatry | Outcome Measure

Ireland
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Completed

ESK981 in Treating Patients With Metastatic Castrate-Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Metastatic Prostate Carcinoma | PSA Progression | Stage IV Prostate Adenocarcinoma AJCC v7 | Castration Levels of Testosterone

United States
Mayo Clinic
National Cancer Institute (NCI)

Terminated

Perampanel for the Reduction of Seizure Frequency in Patients With High-grade Glioma and Focal Epilepsy

Malignant Glioma | WHO Grade 3 Glioma | Intractable Epilepsy | Seizure Disorder | WHO Grade 2 Glioma

United States
Neurological Associates of West Los Angeles

Enrolling by invitation

Near-Infrared Laser Stimulation for Various Neurological Conditions

Neurodegenerative Diseases | Anxiety Disorders | Traumatic Brain Injury | Chronic Traumatic Encephalopathy | Refractory Depression

United States
University of California, San Francisco
National Cancer Institute (NCI)

Terminated

Selinexor in Treating Patients With Abiraterone Acetate and/or Enzalutamide Refractory Metastatic Castration-Resistant Prostate Cancer

PSA Progression | Metastatic Prostate Carcinoma in the Soft Tissue | Hormone-Resistant Prostate Cancer | Stage IV Prostate Adenocarcinoma AJCC v7 | Castration Levels of Testosterone | Prostate Carcinoma Metastatic in the Bone

United States
Assistance Publique - Hôpitaux de Paris
Ministry of Health, France

Terminated

Renal Artery Stenting in Patients With Documented Resistant Hypertension and Atherosclerotic Renal Artery Stenosis (ANDORRA) (ANDORRA)

Hypertension | Hypertension Resistant to Conventional Therapy | Angiographically Proven Grade III Unilateral or Bilateral Atherosclerotic Renal Artery Stenosis (ARAS) Greater Than or Equal to 60 Percent

France
PolyMedix, Inc.

Completed

Initial Treatment for Acute Bacterial Skin Infections (ABSSSI) Caused by Staphylococcus Aureus

Acute Bacterial Skin and Skin-structure Infection(ABSSSI) Due to Staphylococcus Aureus (MSSA) | (Susceptible or Methicillin Resistant)

Canada, Russian Federation, Ukraine
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Nivolumab With or Without Ipilimumab in Treating Patients With Recurrent or High Grade Gynecologic Cancer With Metastatic Peritoneal Carcinomatosis

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Peritoneal Carcinomatosis | Malignant Peritoneal Neoplasm | Recurrent Endometrial Carcinoma | Stage IVB Uterine Corpus Cancer AJCC v8 | Recurrent Cervical Carcinoma | Metastatic Malignant Female... and other conditions

United States
Essen Biotech

Not yet recruiting

Fourth-gen CAR T Cells Targeting BCMA/CD19 for Refractory Systemic Lupus Erythematosus (SLE) (BAH242)

Autoimmune Diseases | Systemic Lupus Erythematosus | Systemic Sclerosis | Lupus Nephritis | Microscopic Polyangiitis | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis | Sjogren's Syndrome | Idiopathic Inflammatory Myopathies | Granulomatous Polyangiitis

China
University of Pennsylvania
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other collaborators

Recruiting

VCRC Tissue Repository

Giant Cell Arteritis | Microscopic Polyangiitis | Churg-Strauss Syndrome | Polyarteritis Nodosa | Eosinophilic Granulomatosis With Polyangiitis | Henoch-Schonlein Purpura | Takayasu Arteritis | Aortitis | IgA Vasculitis | Granulomatosis With Polyangiitis (Wegener's) | Cutaneous Vasculitis

United States, Canada
University of South Florida
Boston University; University of Pennsylvania; Wayne State University; University...

Completed

VCRC Patient Contact Registry Patient-Reported Data Validation Study

Giant Cell Arteritis | Microscopic Polyangiitis | Churg-Strauss Syndrome | Polyarteritis Nodosa | Takayasu's Arteritis | Behcet's Disease | Wegener Granulomatosis

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Abiraterone Acetate, Prednisone, and Apalutamide With or Without Ipilimumab or Cabazitaxel and Carboplatin in Treating Patients With Metastatic Castration-Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Metastatic Prostate Carcinoma | PSA Progression | Stage IV Prostate Adenocarcinoma AJCC v7 | Castration Levels of Testosterone

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...
Novartis; Prostate Cancer Clinical Trials Consortium

Completed

Enzalutamide With Ribociclib in Treating Patients With Metastatic Castrate-Resistant, Chemotherapy Naive Prostate Cancer That Retains Retinoblastoma Expression

Castration-Resistant Prostate Carcinoma | Metastatic Prostate Carcinoma | Stage IV Prostate Cancer AJCC v7 | Prostate Carcinoma Metastatic in the Bone

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Durvalumab and Tremelimumab in Treating Chemotherapy Naive Patients With Metastatic Castration-Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Prostate Adenocarcinoma | Stage IV Prostate Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Bone | Stage IVA Prostate Cancer AJCC v8 | Stage IVB Prostate Cancer AJCC v8

United States
Jonsson Comprehensive Cancer Center

Terminated

Effect of Androgen Receptor Signaling Inhibitors on 68Ga-PSMA-11 PET/CT Imaging in Patients With Castration-Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Metastatic Prostate Carcinoma | Stage IVA Prostate Cancer AJCC v8 | Stage IVB Prostate Cancer AJCC v8 | Stage IV Prostate Cancer American Joint Committee on Cancer (AJCC) v8

United States
Ospedale Andrea Tortora di Pagani

Unknown

Evaluation of Cardiotoxicity and Hypertension in Patients With Non Metastatic Castration Resistant Prostatic Carcinoma (Apa-CARDIO1)

Castration-resistant Prostate Cancer

Italy
Methodist Health System

Unknown

Comparison of Solid Organ Transplant

Gram-Negative Bacterial Infections | Hospital-acquired Pneumonia | Healthcare-associated Pneumonia | Gram-negative Bacteremia | Multidrug-Resistant Organism

United States
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Not yet recruiting

Safety and Efficacy of TT-00420 Tablets Combined With Toripalimab Injection in Advanced Urological Tumors

Urothelial Carcinoma | Metastatic Castration-resistant Prostate Cancer | Clear Cell Renal Carcinoma

China
Hospital Ruber Internacional
Zogenix, Inc.

Recruiting

Fenfluramine for the Treatment of Different Types of Developmental and Epileptic Encephalopathies: a Pilot Trial Exploring Epileptic and Non-epileptic Outcomes (FENDEEP)

Refractory Epilepsy | STXBP1 Encephalopathy With Epilepsy | SYNGAP1 Encephalopathy | Inv Dup(15) Encephalopathy | Multifocal or Bilateral Malformations of Cortical Development | Continuous Spike and Waves During Slow Sleep

Spain
Hospital Ruber Internacional

Recruiting

Galactose Supplementation for the Treatment of MOGHE (GATE)

Refractory Epilepsy | SLC35A2-CDG - Solute Carrier Family 35 Member A2 Congenital Disorder of Glycosylation

Spain
University of Michigan Rogel Cancer Center
Pfizer; Acrotech Biopharma Inc.

Recruiting

Talazoparib in Combination With Belinostat for Metastatic Breast Cancer, Metastatic Castration Resistant Prostate Cancer, and Metastatic Ovarian Cancer

Metastatic Breast Cancer | Metastatic Castration-resistant Prostate Cancer | Metastatic Ovarian Carcinoma

United States
Seattle Institute for Biomedical and Clinical Research
VA Puget Sound Health Care System; Prostate Cancer Foundation

Terminated

Docetaxel and Carboplatin for Patients With mCRPC and DNA-Repair Deficiencies

Metastatic Prostate Carcinoma | Recurrent Prostate Carcinoma | Stage IV Prostate Cancer | Hormone-Resistant Prostate Cancer

United States
Novartis Pharmaceuticals

Completed

Phase I Study of LFA102 in Patients With Prolactin Receptor-positive Castration-resistant Prostate Cancer or Prolactin Receptor-positive Metastatic Breast Cancer

Metastatic Breast Cancer | Castration-resistant Prostate Cancer | Uterine Leiomyoma

Spain, Belgium, Italy, United States
Al-Azhar University

Unknown

Comparative Clinical Study Between Colistin-Tigecycline Combined Therapy Versus Colistin-Meropenem Combined Therapy in Treatment of Blood Stream Infections With Multidrug-Resistant Klebsiella Pneumoniae

Treatment of Blood Stream Infections Due to Multidrug-Resistant Klebsiella Pneumoniae

Egypt
Duke University

Completed

H.O.P.E: Helping Ovarian Cancer Patients Cope

Palliative Care | Platinum-resistant Ovarian Cancer | Recurrent Ovarian Cancer

United States
Universidade Federal do Rio de Janeiro
Financiadora de Estudos e Projetos; Conselho Nacional de Desenvolvimento Científico...

Completed

Efficacy of CPAP Treatment on Blood Pressure of Resistant Hypertension Patients With Obstructive Sleep Apnea Syndrome

Obstructive Sleep Apnea Syndrome | Resistant Hypertension

Brazil
University of Sao Paulo General Hospital

Completed

Yellow Fever Vaccine in Patients With Rheumatic Diseases

Rheumatoid Arthritis | Systemic Sclerosis | Granulomatosis With Polyangiitis | Juvenile Idiopathic Arthritis | Sjogren's Syndrome | Takayasu Arteritis | Spondyloarthritis | Juvenile Dermatomyositis | Mixed Connective Tissue Disease | Systemic Lupus | Inflammatory Myopathy

Brazil
Orlando VA Medical Center

Recruiting

Photobiomodulation for Myofascial Pelvic Pain (PMPP)

Pelvic Pain | Levator Ani Syndrome | Chronic Pelvic Pain Syndrome | Spastic Pelvic Floor Syndrome | Myalgia of Pelvic Floor

United States
Milton S. Hershey Medical Center
National Center for Complementary and Integrative Health (NCCIH)

Recruiting

Inositol Supplementation to Treat PCOS (INSUPP-PCOS) (INSUPP-PCOS)

Polycystic Ovary Syndrome | Hyperandrogenism | Insulin Resistance | Glucose Intolerance | Anovulation | Metabolic Complication

United States
Albert Einstein College of Medicine

Completed

Effect of Obstructive Sleep Apnea Syndrome on Insulin Sensitivity and Cardiovascular Risk in PCOS Adolescents

Obstructive Sleep Apnea Syndrome | Polycystic Ovary Syndrome | Sleep Apnea

United States
MacroGenics

Active, not recruiting

A Study of Vobramitamab Duocarmazine in Participants With Metastatic Castration Resistant Prostate Cancer and Other Solid Tumors (Tamarack)

Melanoma | Non-small Cell Lung Cancer | Small-cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Anal Cancer | Malignant Melanoma | Non-small Cell Carcinoma | Oral Squamous Cell Carcinoma | Small Cell Carcinoma | Laryngeal Squamous Cell Carcinoma | Carcinoma, Squamous Cell of Head and Neck | Castration-Resistant... and other conditions

Spain, Australia, United States, Korea, Republic of, France, United Kingdom, Italy, Belgium, Poland
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

PSCA-CAR T Cells in Treating Patients With PSCA+ Metastatic Castration Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Metastatic Prostate Carcinoma | Stage IV Prostate Cancer AJCC v8 | Stage IVA Prostate Cancer AJCC v8 | Stage IVB Prostate Cancer AJCC v8

United States
University of California, San Francisco
Janssen Pharmaceuticals

Active, not recruiting

Apalutamide With or Without Stereotactic Body Radiation in Treating Castration-Resistant Prostate Cancer (PILLAR)

Castration-Resistant Prostate Carcinoma | PSA Progression | Stage IV Prostate Adenocarcinoma AJCC v7 | Castration Levels of Testosterone

United States
Vascular Biogenics Ltd. operating as VBL Therapeutics
GOG Foundation

Completed

A Study of VB-111 With Paclitaxel vs Paclitaxel for Treatment of Recurrent Platinum-Resistant Ovarian Cancer (OVAL) (OVAL)

Recurrent Platinum Resistant Ovarian Cancer

United States, Israel, Japan, Poland, Spain
Bolan Medical Complex Hospital Quetta Pakistan

Completed

Predictors of Foot Amputation in Diabetic Foot Ulcers

Diabetic Foot | Amputation | Diabetic Foot Ulcer | Antibiotic Resistant Strain

Pakistan
Cancer Institute and Hospital, Chinese Academy...
Jiangsu HengRui Medicine Co., Ltd.

Active, not recruiting

Apatinib Combined With PLD vs PLD for Platinum-resistant Recurrent Ovarian Cancer (APPROVE)

Platinum-resistant Recurrent Ovarian Cancer

China
AstraZeneca
Merck Sharp & Dohme LLC; Myriad Genetic Laboratories, Inc.

Completed

Efficacy and Safety Study of Cediranib in Combination With Olaparib in Patients With Recurrent Platinum-Resistant Ovarian Cancer (CONCERTO)

Recurrent Platinum Resistant Ovarian Cancer

United States
Entasis Therapeutics

Completed

Study to Evaluate the Efficacy and Safety of Intravenous Sulbactam-ETX2514 in the Treatment of Patients With Infections Caused by Acinetobacter Baumannii-calcoaceticus Complex (ATTACK)

Bacteremia | Ventilator-associated Bacterial Pneumonia | Acinetobacter Baumannii-calcoaceticus Complex | Hospital-acquired Bacterial Pneumonia | Colistin Resistant ABC

United States, Belarus, Brazil, China, Greece, Hungary, India, Israel, Korea, Republic of, Lithuania, Mexico, Peru, Puerto Rico, Russian Federation, Taiwan, Thailand, Turkey
Peking Union Medical College Hospital

Unknown

Camrelizumab /Apatinib for Recurrent Platinum-resistant Ovarian Cancer

Recurrent Platinum-resistant Ovarian Cancer

China
Esther Soler

Not yet recruiting

Identification of Biomarkers for the Study of the Diabetic Foot and Evolution. (SCFOOT)

Diabetes Mellitus | Diabetic Foot | Metabolic Syndrome | Sarcopenia | Neuropathy, Diabetic | Vascular Disease, Peripheral
Stanford University

Not yet recruiting

Impact of a Ketogenic Diet on Metabolic and Psychiatric Health in Patients With Bipolar Illness

Obesity | Metabolic Syndrome | Bipolar Disorder | Bipolar and Related Disorders | Bipolar Depression | Weight Gain | Bipolar I Disorder | Ketogenic Dieting | Bipolar Disorder I | Bipolar II Disorder | Psychotropic Agents Causing Adverse Effects in Therapeutic Use | Brain Metabolic Disorder | Bipolar Disorder, Type... and other conditions

United States
Guangzhou Women and Children's Medical Center
University of Birmingham

Recruiting

Offspring Born to Mothers With Polycystic Ovary Syndrome in Guangzhou Cohort Study (PCOS-BIG)

Hyperandrogenism | Insulin Resistance | PCOS | Metabolic Disturbance | Epigenetics | Offspring, Adult | Endocrine Disorder

China
Barts & The London NHS Trust

Terminated

CGM (Continuous Glucose Monitoring) Use in Diagnosis of Spontaneous and Reactive Hypoglycaemia

Insulin Resistance | Insulinoma | Hypoglycemia Unawareness | Hypoglycemia Non-Diabetic | Insulin Hypoglycemia | Hypoglycemia, Reactive | Hypoglycaemia Night | Insulinoma; Malignant, Pancreas | Spontaneous Hypoglycemia | Neuro Endocrine Tumours

United Kingdom
University of Eastern Finland

Active, not recruiting

Kuopio Ischaemic Heart Disease Risk Factor Study (Nutrition Component)

Depression | Liver Diseases | Cardiovascular Diseases | Diabetes | Cancer | Atherosclerosis | Death | Metabolic Syndrome | Chronic Disease | Cognitive Decline | Infection | Pain, Chronic | Inflammatory Disease
Massachusetts General Hospital

Terminated

Study to Identify Markers of Insulin Resistance During Growth Hormone Treatment for Short Stature

Turner Syndrome | Idiopathic Short Stature

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of an Anti-cancer Drug, Elimusertib (BAY 1895344) ATR Inhibitor, to the Chemotherapy Treatment (Gemcitabine) for Advanced Pancreatic and Ovarian Cancer, and Advanced Solid Tumors

Advanced Malignant Solid Neoplasm | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma | Primary Peritoneal High Grade Serous Adenocarcinoma | Advanced Pancreatic Adenocarcinoma | Platinum-Resistant... and other conditions

United States
National Cancer Institute (NCI)

Recruiting

Testing the Combination of APG-1252 (Pelcitoclax) and Cobimetinib in Recurrent Ovarian and Endometrial Cancers

Recurrent Fallopian Tube Carcinoma | Recurrent Primary Peritoneal Carcinoma | Recurrent Endometrial Carcinoma | Stage III Uterine Corpus Cancer AJCC v8 | Stage IV Uterine Corpus Cancer AJCC v8 | Recurrent Platinum-Resistant Ovarian Carcinoma | Metastatic Fallopian Tube Carcinoma | Metastatic Primary... and other conditions

United States

Clinical Trials on Anti-biotic Resistance

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Drug Interventions

CROs by country

CROs in Ethiopia

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