Clinical Trials on Antiviral Toxicity

Total 729 results

Washington University School of Medicine
American Academy of Clinical Toxicology

Not yet recruiting

Rivastigmine to Prevent Recurrence of Antimuscarinic Delirium (RIVA-AP)

Anticholinergic Toxicity

United States
Universiti Sains Malaysia

Completed

KCNH2 Polymorphisms on the QTc Interval in Kelantanese Malays Patients Receiving Methadone Maintenance Therapy (MMT)

Opioid Dependence | Methadone Toxicity | HERG Gene Mutation

Malaysia
Azienda Ospedaliera di Padova

Completed

Efficacy and Safety of Continuous Infusion of Ketamine in Pediatric Intensive Care Unit (KISS Study) (KISS)

Analgesia | Sedation Complication | Bronchospasm | Ketamine Toxicity

Italy
Children's National Research Institute

Completed

Sound Levels in the Pediatric Cardiac Critical Care Unit and Their Correlation With Sedation Administration, Delirium Scores and Patient Heart Rate

Noise Exposure | Sedative Toxicity | Sedative Withdrawal Delirium

United States
Yonsei University

Not yet recruiting

Clinical Trial for Non-inferiority and Safety of Tenofovir Alafenamide and Tenofovir Disoproxil Fumarate in Patients With Hematologic Malignancies Who Require Prophylactic Hepatitis B Antiviral Treatment

Patients With Malignant Blood Disease Requiring Hepatitis B Antiviral Medication
Hospital Universitario de Valme
Instituto de Salud Carlos III

Unknown

Prediction of Liver-related Outcomes After HCV Cure

Hepatocellular Carcinoma | Hepatitis C, Chronic | Hepatic Decompensation | Sustained Virological Response | Direct-acting Antivirals

Spain
101 Therapeutics

Active, not recruiting

Study to Evaluate Pharmacokinetics, Safety & Tolerability of 101-PGC-005 in Healthy, Adult, Human Subjects

Virus Diseases | COVID-19 | Infectious Disease | Glucocorticoids Toxicity

India
University Hospital Tuebingen

Withdrawn

Computer-based Dosage Calculation for Antibiotics

Acute Kidney Insufficiency | Anti-Infective Agent Toxicity

Germany
Campus Bio-Medico University

Unknown

Volume De-escalation in Neoadjuvant Radiochemotherapy of Rectal Cancer

Toxicity

Italy
Joel Greenberger

Terminated

MnSOD (Esophageal Protectant) to Prevent Esophagitis During Radiation/Chemotherapy Treatment for Non-Small Cell Lung Cancer (NSCLC) (MnSOD)

Toxicity | Esophageal

United States
University of Aarhus

Completed

Cognitive Function After Radiation Therapy for Brain Tumours (WP-12-pre)

Radiation Toxicity | Primary Brain Tumor

Denmark
Celularity Incorporated

Recruiting

Natural Killer Cell (CYNK-001) Infusions in Adults With AML (CYNK001AML01)

Neoplasms | Neoplasms by Histologic Type | Hematologic Diseases | Leukemia | Leukemia, Myeloid | Leukemia, Myeloid, Acute | Hematologic Neoplasms | Physiological Effects of Drugs | Peripheral Nervous System Agents | Analgesics | Analgesics, Non-narcotic | Antimetabolites, Antineoplastic | Leukemia in Remission | Relapsed... and other conditions

United States
Azienda Ospedaliera di Padova
University of Padova; Regione Veneto

Completed

Different PEG-interferon and Ribavirin Schedules for Chronic Hepatitis C in the Real Clinical Practice.

Hepatitis C Virus | Chronic Liver Disease | Therapeutic Uses | Viral Hepatitis | Antiviral Agents

Italy
Odense University Hospital

Recruiting

COr Loco-regional Advanced Lung Cancer Treated With Chemo-radiotherapy (COLA) (COLA)

Radiation Toxicity | Cardiac Disease | Cardiac Toxicity | Lung Cancer Stage III | Lung Cancer Stage II

Denmark
McMaster University
St. Joseph's Healthcare Hamilton; Juravinski Cancer Center

Recruiting

Financial Toxicity in Breast Cancer Surgery

Breast Cancer

Canada
Battelle Memorial Institute

Completed

Reduced Nicotine Cigarettes in Smokers With and Without Alcohol Use Disorder (RedNic)

Alcohol Drinking | Cigarette Smoking Toxicity

United States
Imperial College London

Completed

Predictive Model of Therapy Outcomes in Breast Cancer Patients

Toxicity From Medication (Endocrine Treatment and Chemotherapy) Given for Breast Cancer Treatment.

United Kingdom
Laboratorios Sophia S.A de C.V.

Recruiting

Study to Evaluate the Safety and Tolerability of PRO-231 Ophthalmic Solution Versus VIGAMOXI® on the Ocular Surface of Healthy Subjects.

Bacterial Conjunctivitis | Ophthalmological Agent Toxicity

Mexico
Cancer Institute and Hospital, Chinese Academy...

Completed

A Prospective Study of Hypothyroidism After Radiotherapy for Breast Cancer

Breast Neoplasms | Hypothyroidism | Radiation Toxicity

China
Fundacion CRIS de Investigación para Vencer el...
Apices Soluciones S.L.; Amgen

Completed

Skin Toxicity in Patients With Metastatic Colorectal Cancer Treated With Anti-EGFR and Chemotherapy (DERMIA) (DERMIA)

Skin Toxicity

Spain
Peking Union Medical College Hospital

Unknown

the Association Between Blood's and Urinary Heavy Metal Level in Pregnant Women and the Spontaneous Abortion (HMLandSA)

Heavy Metal Toxicity | Spontaneous Abortion

China
Royal Marsden NHS Foundation Trust

Unknown

Parotid-Sparing Intensity-Modulated Radiation Therapy Compared With Conventional Radiation Therapy in Treating Patients With Oropharyngeal or Hypopharyngeal Cancer Who Are at High Risk of Radiation-Induced Xerostomia

Head and Neck Cancer | Xerostomia | Radiation Toxicity

United Kingdom
Herlev and Gentofte Hospital
Odense University Hospital; Zealand University Hospital; Aarhus University Hospital and other collaborators

Recruiting

Monitoring of Arrhythmias in Patients Treated With Antipsychotics (MAPP)

Death, Sudden, Cardiac | Arrythmia | Antipsychotics and Neuroleptics Toxicity

Denmark
Peking University People's Hospital
Jiangsu HengRui Medicine Co., Ltd.

Completed

Apatinib With Ifosfamide Plus Etoposide for Relapsed or Refractory Osteosarcoma (OAIE) (OAIE)

Toxicity | Effect of Drug | Drug

China
University of Arkansas

Terminated

Phase I Clinical Trial of GRID Therapy in Pediatric Osteosarcoma of the Extremity

Radiation Toxicity | Osteosarcoma in Children

United States
Shanghai Zhongshan Hospital

Unknown

Apatinib Plus XELOX as Neoadjuvant Therapy in Locally Advanced Gastric Cancer

Gastric Cancer | Chemotherapy Effect | Chemotherapeutic Toxicity

China
University of California, San Francisco
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)

Withdrawn

Cigarette Harm Reduction With Electronic Cigarette Use (NIDA-SREC)

Cardiovascular Risk Factor | Nicotine Dependence | Nicotine Dependence, Cigarettes | Nicotine Withdrawal | Tobacco Toxicity

United States
National Cancer Institute, Egypt

Completed

Study of Metronomic Capecitabine and Oxaliplatin Versus XELOX in Egyptian Metastatic Colorectal Cancer Patients

Toxicity | Survival | Clinical Response
Universitaire Ziekenhuizen KU Leuven
Bristol-Myers Squibb

Completed

Apixaban in End-stage Kidney Disease : A Pharmacokinetics Study

ESRD | Anticoagulant Toxicity

Belgium
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Zinc Sulfate in Preventing Loss of Sense of Taste in Patients Undergoing Radiation Therapy for Head and Neck Cancer

Head and Neck Cancer | Radiation Toxicity | Dysgeusia | Oral Complications
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Radiation Therapy and Cisplatin With or Without Amifostine for Patients With Stage IIIB or IVA Cervical Cancer

Cervical Cancer | Radiation Toxicity

United States
Erasmus Medical Center
Gilead Sciences

Unknown

Switching From Tenofovir Disoproxil Fumarate to Abacavir or Tenofovir Alafenamide (BACTAF)

Hiv | Renal Insufficiency,Chronic | Therapeutic Agent Toxicity

Netherlands
Massimo Falconi

Recruiting

Financial Toxicity and Patient-Reported Outcomes in GEP-NEN During Treatment (FiReNEN)

Neuroendocrine Tumors

Italy
Ospedale San Carlo Borromeo

Active, not recruiting

Panitumumab Skin Toxicity Prevention Trial (PaSTo)

Colorectal Cancer Metastatic | Skin Toxicity

Italy
National and Kapodistrian University of Athens

Completed

Transthoracic Echocardiography of Inferior Vena Cava Before Spinal Anesthesia Can Predict Hypotension

Intraoperative Complications | Spinal Anesthetic Toxicity | Inferior Vena Cava Abnormality

Greece
Yonsei University

Unknown

Switching From Tenofovir Disoproxi Fumarate to Tenofovir Alafenamide in Chronic Hepatitis B Patients With Antiviral Resistance

Hepatitis B | Antiviral Drug Adverse Reaction
AbbVie

Completed

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of ABT-493 and ABT-530 With and Without Ribavirin in Adults With HCV Who Failed a Prior DAA Containing Therapy

Chronic Hepatitis C | Hepatitis C Virus | HCV | Direct-Acting Antiviral Agent (DAA)-Experienced
University of Nebraska
National Cancer Institute (NCI)

Completed

Cardiac Magnetic Resonance Imaging in Patients With Non-Hodgkin Lymphoma or Hodgkin Lymphoma Receiving Doxorubicin

Lymphoma | Cardiac Toxicity | Chemotherapeutic Agent Toxicity

United States
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Octreotide in Preventing or Reducing Diarrhea in Patients Receiving Chemoradiotherapy for Anal or Rectal Cancer

Colorectal Cancer | Anal Cancer | Drug/Agent Toxicity by Tissue/Organ | Radiation Enteritis

United States
Centre Francois Baclesse
Région Normandie

Recruiting

Neurocognitive Impact of Different Irradiation Modalities for Patients With Grade I-II Skull Base Meningioma: (CANCER-COG)

Meningioma | Radiation Toxicity

France
Rabin Medical Center

Completed

IMRT Versus 3DCRT for Locally Advanced Rectal Cancer, Prospective Phase II Study.

Rectal Cancer | Toxicity Due to Radiotherapy | Radiotherapy

Israel
Guangdong Provincial Hospital of Traditional Chinese...

Completed

Safety and Efficacy of Expanded Allogeneic AD-MSCs in Patients With Moderate to Severe Psoriasis (ADMSP)

Psoriasis | Drug Effect | Drug Toxicity | Mesenchymal Stromal Cells

China
Guangdong Provincial Hospital of Traditional Chinese...

Completed

Efficacy and Safety of AD-MSCs Plus Calpocitriol Ointment and PSORI-CM01 Granule in Psoriasis Patients

Psoriasis | Drug Effect | Drug Toxicity | Mesenchymal Stromal Cells

China
Massachusetts General Hospital
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Active, not recruiting

Tau/P-Tau and Neurocognitive Outcomes in Children

Postoperative Cognitive Dysfunction | Child Development | General Anesthetics Toxicity

United States
Institut Cancerologie de l'Ouest

Terminated

Pre-emptive Cycline Treatment on Cetuximab Induced Skin Toxicity in Colorectal Cancer (SKINUX)

Colorectal Cancer Metastatic | Skin Toxicity

France
University of Wisconsin, Madison
National Institute on Deafness and Other Communication Disorders (NIDCD)

Completed

Vitamin A Liver Reserves and Serum Markers of Vitamin A in US Adults at Time of Death

Vitamin A Deficiency | Vitamin A Toxicity

United States
University Hospital, Rouen
Ligue contre le cancer, France

Terminated

Tc-99m Renography and Cisplatin-induced Nephrotoxicity

Cancer | Kidney Failure | Drug Toxicity
Northwestern University
National Cancer Institute (NCI)

Terminated

Cryotherapy in Preventing Peripheral Neuropathy and Nail Toxicity in Patients With Breast Cancer Who Are Receiving Paclitaxel

Pain | Peripheral Neuropathy | Stage IV Breast Cancer | Stage II Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IA Breast Cancer | Stage IB Breast Cancer | Stage IIIC Breast Cancer | Recurrent Breast Cancer | Chemotherapeutic Agent Toxicity | Therapy-related Toxicity

United States
Assiut University

Completed

Hematologic Profile, Vit. B12 and Folic Acid in Cirrhotics Received Sofosbuvir and Daclatasvir With or Without Ribavirin

Liver Cirrhoses | Chronic Hepatitis c | Directly Acting Antivirals

Egypt
First Affiliated Hospital of Chengdu Medical College

Recruiting

Deep-sea Fish Oil for Prevention of Acute Radiation-induced Esophagitis

Esophageal Cancer | Esophagitis | Radiation Toxicity

China

Clinical Trials on Antiviral Toxicity

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