Clinical Trials on Aortic Valve Calcification

Total 4423 results

Royal Brompton & Harefield NHS Foundation Trust

Completed

Does Cardiac REhabilitation Improve Functional, Independence, Frailty and Emotional outCOmes Following Trans Catheter Aortic ValvE Replacement? (RECOVER-TAVR)

Aortic Stenosis

United Kingdom
Sahlgrenska University Hospital, Sweden

Completed

Effect of Steroids on Cerebral Inflammation and Neuronal Damage After Surgical Aortic Valve Replacement

Aortic Stenosis

Sweden
OCEAN-SHD Study Group

Recruiting

Non-antithrombotic Therapy After Transcatheter Aortic Valve Implantation Trial

Aortic Stenosis | Aspirin | TAVI(Transcatheter Aortic Valve Implantation) | DAPT(Dual Antiplatelet Therapy) | SAPT(Single Antiplatelet Therapy)

Japan
The Cleveland Clinic
National Institutes of Health (NIH)

Completed

The Effect of the Hyperinsulinemic Normoglycemic Clamp on Myocardial Function and Utilization of Glucose

Hyperglycemia | Aortic Stenosis | Cardiac Surgery | Aortic Valve Replacement

United States
Maastricht University Medical Center

Unknown

Bicuspid Aortic Valve Stenosis and the Effect of vItamin K2 on Calciummetabolism on 18F-NaF PET/MRI (BASIK2)

Aortic Valve Stenosis | Bicuspid Aortic Valve

Netherlands
Universitair Ziekenhuis Brussel

Completed

Implementation of Non-size Markers Derived From 4D Flow MRI of Patients With Aortic Disease.

Aortic Valve Disease | Aortic Aneurysm

Belgium
University Medical Centre Ljubljana

Not yet recruiting

Conventional Versus Left Bundle Branch Pacing in TAVI

Heart Failure | Aortic Valve Stenosis | Pacemaker-Induced Cardiomyopathy | Transcatheter Aortic Valve Implantation

Slovenia
Edwards Lifesciences

Completed

Surgical Treatment of Aortic Stenosis With a Next Generation Surgical Aortic Valve (TRITON)

Aortic Valve Stenosis | Aortic Valve Stenosis With Insufficiency

Austria, Germany
University of Göttingen

Recruiting

Exercise CMR in (p)LF-LG AS

Aortic Stenosis, Severe

Germany
Romanian Society of Cardiology

Recruiting

Romanian National Registry of Outcomes After Transcatheter Aortic Valve Implantation in Patients With Severe Aortic Stenosis - RO-TAVI (RO-TAVI)

Aortic Valve Stenosis | Aortic Stenosis Symptomatic

Romania
Medtronic Cardiovascular

Active, not recruiting

Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Severe, Symptomatic Aortic Stenosis in Intermediate Risk Subjects Who Need Aortic Valve Replacement (SURTAVI). (SURTAVI)

Severe Aortic Stenosis

United States, Netherlands, Canada, Spain, Denmark, United Kingdom, Switzerland, Germany, Sweden
Symetis SA

Completed

ACURATE TF™ Transfemoral Aortic Bioprosthesis for Implantation in Patients With Severe Aortic Stenosis (2011-03) (2011-03)

Aortic Stenosis Symptomatic

Germany, Brazil
Medtronic Cardiovascular

Completed

Safety and Efficacy Continued Access Study of the Medtronic CoreValve® System in the Treatment of Symptomatic Severe Aortic Stenosis in Very High Risk Subjects and High Risk Subjects Who Need Aortic Valve Replacement

Severe Aortic Stenosis

United States
Abbott Medical Devices

Completed

First in Human Experience of the St. Jude Medical TAVI Valve and Delivery System (SJM TAVI FIH)

Symptomatic Aortic Stenosis

United Kingdom
Abbott Medical Devices

Completed

Portico TAVI Implant With Transfemoral Delivery System

Symptomatic Aortic Stenosis

United Kingdom, Germany, Netherlands, Denmark, Australia
Symetis SA

Completed

ACURATE TF™ Transfemoral Aortic Bioprosthesis for Implantation in Patients With Severe Aortic Stenosis:CE-approval Cohort

Symptomatic Aortic Stenosis

Germany, Japan, Brazil
Symetis SA

Completed

Feasibility Trial on ACURATE™ Transapical Implantation in Patients With Severe Symptomatic Aortic Stenosis (2009-01) (TA-FIM)

Aortic Stenosis Symptomatic

Germany
Academisch Medisch Centrum - Universiteit van Amsterdam...
Edwards Lifesciences

Unknown

Feasibility of Continuous Noninvasive Finger Arterial Blood Pressure Measurement for Detection and Staging of Aortic Stenosis (COaRt)

Aortic Stenosis, Calcific

Netherlands
HLT Inc.

Withdrawn

HLT transfemOral Replacement of aortIc Valve Via transcatherteriZatiON CANADA (HORIZON CANADA)

Severe Aortic Stenosis

Canada
Yonsei University

Recruiting

Genetic Test Based Risk Prediction of Early Calcific Aortic Valve Disease in Patients With Bicuspid Aortic Valve

Bicuspid Aortic Valve

Korea, Republic of
Centre Hospitalier Universitaire, Amiens

Recruiting

Follow-up of a Cohort of Patients With Aortic Valve Bicuspidia

Aortic Valve, Bicuspid

France
Boston University
Massachusetts General Hospital; National Heart, Lung, and Blood Institute (NHLBI) and other collaborators

Active, not recruiting

Identification of Genetic Causes of Bicuspid Aortic Valve Disease (BAV Genetics)

Bicuspid Aortic Valve

United States
Assistance Publique Hopitaux De Marseille

Unknown

Whole Exome Sequencing in Bicuspid Aortic Valve Patients

Bicuspid Aortic Valve

France
Abbott Medical Devices

Active, not recruiting

The CONFIDENCE Registry

Severe Aortic Stenosis | Symptomatic Degenerative Aortic Stenosis

Spain, Italy, United Kingdom, Germany, Switzerland, Czechia, Australia, Belgium, Poland
Edwards Lifesciences

Completed

PARTNER II Trial: Placement of AoRTic TraNscathetER Valves II - Nested Registry 3/Valve-in-Valve (PII NR3/ViV)

Aortic Stenosis | Cardiomyopathy, Hypertrophic

United States, Canada
University Hospital, Montpellier

Completed

Vascular Complications and Bleeding After Transfemoral TAVI

Severe and Symptomatic Aortic Stenosis | Undergoing TAVI

France
University of Bari

Unknown

Study of Administration Of Antithrombin in Patients With Low Plasmatic Levels of Antithrombin After Cardiac Surgery (ATIII)

Aortic Valve Stenosis | Mitral Valve Insufficiency | Aortic Valve Insufficiency | Acute Coronary Syndrome | Mitral Valve Stenosis

Italy
Fondazione Toscana Gabriele Monasterio
Nicolaus Copernicus University

Recruiting

Ultrasound-guided Femoral Puncture to Reduce Access- Related Complications After TAVR: (ACCESS-TAVR SIRIO)

Transcatheter Aortic Valve Replacement

Italy
Sheba Medical Center

Completed

Post-TAVI Coronary Access Study (PTCA)

Transcatheter Aortic Valve Replacement

Israel
Henry Ford Health System
Henry Ford Hospital

Completed

Physical Therapy and Occupational Therapy After Transcatheter Aortic Valve Replacement (PTOTtAVR)

Transcatheter Aortic Valve Implantation

United States
Boston Scientific Corporation

Completed

REPRISE II: REpositionable Percutaneous Replacement of Stenotic Aortic Valve Through Implantation of Lotus™ Valve System

Transcatheter Aortic Valve Replacement

Spain, United Kingdom, Australia, France, Germany, Italy, Netherlands, Sweden, Switzerland
NVT GmbH

Completed

NVT ALLEGRA TAVI System TF in Failing Surgical Aortic Bioprosthesis (VIVALL)

Transcatheter Aortic Valve Implantation

Germany
French Cardiology Society
Institut National de la Santé Et de la Recherche Médicale, France; Centre National...

Active, not recruiting

Evaluation of Aortic Stiffness as a Prognostic Indicator of Aortic Dilatation in Patients With Bicuspid Aortic Valve by Multimodal Imaging (IRM-BAO)

Bicuspid Aortic Valve

France
St. Antonius Hospital

Completed

Patient Reported Health-Related Quality of Life After Limited Access and Conventional Aortic Valve Replacement (LIAR)

Quality of Life | Aortic Valve Stenosis | Limited Access Aortic Valve Replacement

Netherlands
Matteo Montorfano

Recruiting

Microvascular Function in Patients Undergoing Transcatheter Aortic Valve Implant (TAVI) for Severe Symptomatic Aortic Stenosis: Association With Myocardial Fibrosis

Severe Symptomatic Aortic Stenosis

Italy
Edwards Lifesciences

Active, not recruiting

EARLY TAVR: Evaluation of TAVR Compared to Surveillance for Patients With Asymptomatic Severe Aortic Stenosis (EARLY TAVR)

Heart Diseases | Aortic Stenosis, Severe

United States, Canada
Nantes University Hospital

Completed

Change in Coronary Microcirculation and FFR After TAVI in Patients With Cardiovascular Comorbidities

Severe Symptomatic Aortic Stenosis

France
The Society of Thoracic Surgeons
American College of Cardiology

Completed

Alternative Access Approaches for Transcatheter Aortic Valve Replace (TAVR) in Inoperable Patients With Aortic Stenosis (Inop AA)

Severe Symptomatic Aortic Stenosis
Jung-min Ahn

Recruiting

Long-term Anticoagulation With Oral Factor Xa Inhibitor Versus Vitamin K Antagonist After Mechanical Aortic Valve Replacement (RENOVATE)

Thromboembolism | AORTIC VALVE DISEASES

Korea, Republic of
University Hospital Inselspital, Berne

Terminated

Combined Transcatheter Aortic Valve Implantation and Percutaneous Closure of the Left Atrial Appendage (TAVI-LAAC)

Aortic Valve Disorder

Switzerland, Italy, Germany, Portugal
Jian'an Wang,MD,PhD

Not yet recruiting

Sizing-sTrategy of Bicuspid AoRtic Valve Stenosis With Transcatheter Self-expandable Valve (START)

Aortic Valve Stenosis

China
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Not yet recruiting

A Trial of HS-10511 in Healthy Subjects

Hypertrophic Cardiomyopathy
NYU Langone Health

Enrolling by invitation

OPIE in the Thin Interventricular Septum

Hypertrophic Cardiomyopathy

United States
University of Pittsburgh

Terminated

Genetic Predictors of Outcome in HCM Patients

Hypertrophic Cardiomyopathy

United States
Oregon Health and Science University

Unknown

Perfusion Imaging With Myocardial Contrast Echocardiography in HCM

Hypertrophic Cardiomyopathy

United States
Institut für Pharmakologie und Präventive Medizin
Edwards Lifesciences

Recruiting

The ReTAVI Prospective Observational Registry

Aortic Valve Stenosis | Structural Valve Degeneration | Structural Valve Deterioration

Austria, Spain, Switzerland, France, Italy, Germany, Poland, Canada, Israel, Netherlands, Portugal, United Kingdom
Nantes University Hospital

Completed

Assessment of Osteoblastic Activity With 18F-Fluoride in Aortic Bioprosthesis Structural Valve Dysfunction (SVD) (TEP-SVD)

Aortic Bioprosthesis Structural Valve Dysfunction

France
Nantes University Hospital

Completed

Burden Comorbidities and Transcatheter Aortic Valve Implantation (TAVIQUAL)

Symptomatic Severe Aortic Valve Stenosis in Older Patients

France
Abbott Medical Devices

Completed

FlexNav EU CE Mark Study

Symptomatic Severe Aortic Stenosis

Denmark, Switzerland, United Kingdom, Italy
Abbott Medical Devices

Withdrawn

Assessment of St Jude Medical Portico Re-sheathable Transapical Aortic Valve System (Portico TA EU)

Severe Symptomatic Aortic Stenosis

United Kingdom

Clinical Trials on Aortic Valve Calcification

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Nigeria

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations