Clinical Trials on Aortic Valve Disease

Total 380496 results

REDNVIA Co., Ltd.

Recruiting

A Study to Evaluate the Efficacy and Safety of DA-1229 (Evogliptin) in Patient's Calcific Aortic Valve Disease With Mild to Moderate Aortic Stenosis (EVOID-AS)

Calcific Aortic Valve Disease

United States
Hospital Universitari Vall d'Hebron Research Institute

Completed

Evaluating the Effectiveness of Atorvastatin on the Progression of Aortic Dilatation and Valvular Degeneration in Patients With Bicuspid Aortic Valve (BICATOR)

Bicuspid Aortic Valve

Spain
Instituto Nacional de Cardiologia Ignacio Chavez

Completed

Analysis and Comparative Evaluation of Aortic Calcium by Computed Tomography and Histopathology in Patients With Aortic Stenosis

Aortic Valve Stenosis | Aortic Calcification Valve

Mexico
Guy's and St Thomas' NHS Foundation Trust
King's College London

Not yet recruiting

Outcome Prediction in Patients With Aortic Stenosis After TAVI (PREDICT-TAVI)

Aortic Stenosis, Severe

United Kingdom
University Medical Center Goettingen

Recruiting

Effect of Antifibrotic Therapy on Regression of Myocardial Fibrosis After Transcatheter Aortic Valve Implantation (TAVI) in Aortic Stenosis Patients With High Fibrotic Burden (Reduce-MFA)

Aortic Stenosis, Severe

Germany
University of Leicester
University of Edinburgh

Recruiting

MRI in Randomised Cohorts of Asymptomatic AS

Aortic Stenosis, Severe

United Kingdom
Edwards Lifesciences

Recruiting

PARTNER 3 Trial - Aortic Valve-in-Valve

Aortic Stenosis | Aortic Stenosis, Severe

United States, Canada
Rigshospitalet, Denmark
Odense University Hospital; Sahlgrenska University Hospital, Sweden; Danish Heart... and other collaborators

Active, not recruiting

The Nordic Aortic Valve Intervention Trial (NOTION)

Critical Aortic Stenosis

Denmark, Sweden
Shared Decision Making Resources
Edwards Lifesciences

Completed

Understanding Patient Goals and Preferences to Facilitate Shared Decision Making for Symptomatic Aortic Stenosis

Aortic Stenosis Symptomatic

United States
St. Antonius Hospital

Completed

Patient Reported Health-Related Quality of Life After Limited Access and Conventional Aortic Valve Replacement (LIAR)

Quality of Life | Aortic Valve Stenosis | Limited Access Aortic Valve Replacement

Netherlands
Edwards Lifesciences
Rundo International Pharmaceutical Research & Development Co.,Ltd.; Edwards... and other collaborators

Active, not recruiting

INSPIRIS China PMCF Study (INSPIRIS China)

Aortic Valve Replacement

China
Edwards Lifesciences

Suspended

INSPIRIS RESILIA Aortic Valve, Valve-in-Valve Surveillance Study (INVIVITY)

Aortic Valve Replacement

United States
Matteo Montorfano

Recruiting

Microvascular Function in Patients Undergoing Transcatheter Aortic Valve Implant (TAVI) for Severe Symptomatic Aortic Stenosis: Association With Myocardial Fibrosis

Severe Symptomatic Aortic Stenosis

Italy
Nantes University Hospital

Completed

Change in Coronary Microcirculation and FFR After TAVI in Patients With Cardiovascular Comorbidities

Severe Symptomatic Aortic Stenosis

France
The Society of Thoracic Surgeons
American College of Cardiology

Completed

Alternative Access Approaches for Transcatheter Aortic Valve Replace (TAVR) in Inoperable Patients With Aortic Stenosis (Inop AA)

Severe Symptomatic Aortic Stenosis
Institut für Pharmakologie und Präventive Medizin
Edwards Lifesciences

Recruiting

The ReTAVI Prospective Observational Registry

Aortic Valve Stenosis | Structural Valve Degeneration | Structural Valve Deterioration

Austria, Spain, Switzerland, France, Italy, Germany, Poland, Canada, Israel, Netherlands, Portugal, United Kingdom
University of Bari

Unknown

Study of Administration Of Antithrombin in Patients With Low Plasmatic Levels of Antithrombin After Cardiac Surgery (ATIII)

Aortic Valve Stenosis | Mitral Valve Insufficiency | Aortic Valve Insufficiency | Acute Coronary Syndrome | Mitral Valve Stenosis

Italy
Turku University Hospital
Vifor Pharma

Recruiting

Preoperative Intravenous Ferric Carboxymaltose and Placebo in the Treatment of Patients Undergoing Cardiac Surgery (PREFER-CABG)

Coronary Artery Disease | Postoperative Complications | Aortic Valve Stenosis | Aortic Aneurysm, Thoracic | Mitral Valve Disease

Finland
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Not yet recruiting

A Trial of HS-10511 in Healthy Subjects

Hypertrophic Cardiomyopathy
NYU Langone Health

Enrolling by invitation

OPIE in the Thin Interventricular Septum

Hypertrophic Cardiomyopathy

United States
University of Pittsburgh

Terminated

Genetic Predictors of Outcome in HCM Patients

Hypertrophic Cardiomyopathy

United States
Oregon Health and Science University

Unknown

Perfusion Imaging With Myocardial Contrast Echocardiography in HCM

Hypertrophic Cardiomyopathy

United States
Medtronic Bakken Research Center

Completed

ADVANCE Direct Aortic Study

Aortic Stenosis | Valvular Heart Disease

Netherlands, United Kingdom, Czechia, France, Germany, Italy
Shanghai MicroPort Medical (Group) Co., Ltd.

Unknown

Safety and Efficacy Study of MicroPort's Transcatheter Aortic Valve and Delivery System for TAVI

Aortic Valve Stenosis | Aortic Valve Disease | Aortic Valve Calcification

China
Hospital Universitari Vall d'Hebron Research Institute

Not yet recruiting

Single Perclose Escalation Technique for Vascular Closure in TAVR

Aortic Valve Stenosis | Structural Valve Degeneration | Structural Valve Deterioration

Spain
Edwards Lifesciences

Terminated

RESILIENCE Trial: Evaluation of the Durability of Aortic Bioprostheses/Valves With RESILIA Tissue in Subjects Under 65 (RESILIENCE)

Aortic Valve Replacement

United States
Maria Cecilia Hospital
Ettore Sansavini Health Science Foundation

Completed

Minimally Invasive Versus Conventional Aortic Valve Replacement: a Long Term Registry (SATURNO)

Aortic Valve Surgery

Italy
Cardiawave SA

Completed

A Prospective RegistrY of Cardiac Echographic Loops (ARYEL)

Calcified Aortic Valve

France
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield

Completed

Use of the SonoSite Probe for Measuring Jugular Venous Pressure (PRAGUE)

Aortic Valve Surgery

United Kingdom
CardioGard Medical Ltd.

Completed

Safety and Performance Study of the CardioGard Cannula

Aortic Valve Replacement

Israel, Switzerland, Germany
Nantes University Hospital

Completed

Burden Comorbidities and Transcatheter Aortic Valve Implantation (TAVIQUAL)

Symptomatic Severe Aortic Valve Stenosis in Older Patients

France
Medstar Health Research Institute

Recruiting

Transcatheter Aortic Prosthesis Function: A Long-term Follow-up Study

Aortic Valve Replacement

United States
Corcym S.r.l
LivaNova

Completed

Behavior of Valve Leaflets Following Aortic Valve Implant (BELIEVE)

Aortic-valve Replacement

United States, Canada
University Hospital, Basel, Switzerland

Completed

10 Versus 20 Minutes Treatment of Human Pericardium With Glutaraldehyde in OZAKI Procedure (10vs20-OZAKI)

Aortic Valve Surgery

Switzerland
University Hospital, Clermont-Ferrand
Ministry of Health, France; Abbott Medical Devices; Edwards Lifesciences; Sorin...

Unknown

Comparison Between Three Types of Stented Pericardial Aortic Valves

Aortic Valve Replacement

France
BOIRON
Hospices Civils de Lyon

Completed

Homoeopathic Association in Aortic Valve Surgery (OMEO)

Aortic Valve Replacement

France
Abbott Medical Devices

Completed

FlexNav EU CE Mark Study

Symptomatic Severe Aortic Stenosis

Denmark, Switzerland, United Kingdom, Italy
Abbott Medical Devices

Withdrawn

Assessment of St Jude Medical Portico Re-sheathable Transapical Aortic Valve System (Portico TA EU)

Severe Symptomatic Aortic Stenosis

United Kingdom
Sheba Medical Center

Unknown

Evaluation of Association Between Apical Dysfunction and Trans Apical Access for TAVR, in Patients With Severe Aortic Stenosis, Undergoing Trans Apical Trans Catheter Aortic Valve Replacement (TAP-TAVR).

Severe Symptomatic Aortic Stenosis

Israel
National Heart, Lung, and Blood Institute (NHLBI)

Withdrawn

Structural Heart and Valve Network PROSPECTIVE Registry

Heart Failure | Aortic Valve Stenosis | Mitral Valve Regurgitation | Heart Valve Disease | Tricuspid Valve Regurgitation

United States
LianBio LLC

Completed

Study Evaluating the Pharmacokinetics of Mavacamten in Healthy Adult Chinese Subjects

Hypertrophic Cardiomyopathy

China
HealthCore-NERI
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Valsartan for Attenuating Disease Evolution In Early Sarcomeric HCM (VANISH)

Hypertrophic Cardiomyopathy

United States, Canada
Sunnybrook Health Sciences Centre

Completed

Pilot Study of Cognitive and Functional Outcomes Following TAVI

Aortic Stenosis

Canada
Medtronic Cardiovascular

Active, not recruiting

Medtronic Transcatheter Aortic Valve Replacement (TAVR) Low Risk Bicuspid Study

Bicuspid Aortic Valve

United States
Qilu Hospital of Shandong University

Recruiting

Effects of Levosimendan on Cardiac Function After TAVR in Patients With Heart Failure

Heart Failure | Aortic Stenosis, Severe

China
Abbott Medical Devices

Active, not recruiting

Portico NG Approval Study

Symptomatic Severe Aortic Stenosis

United States, Australia, Denmark, Italy, United Kingdom
Fundación EPIC

Recruiting

Comparison of Allegra vs Sapien Transcatheter Aortic Valves in Valve-In-Valve Indication

Aortic Valve Stenosis | Structural Valve Deterioration

Spain
Carilion Clinic

Terminated

Radial Versus Femoral Secondary Access During TAVI (R-TAVI)

Aortic Stenosis | Aortic Valve Disease | Vascular Access Complication

United States
National and Kapodistrian University of Athens
Centre Hospitalier Universitaire Saint Pierre

Recruiting

Rapid Atrial Pacing After TAVI to Predict Pacemaker Implantation

Aortic Valve Disease | Transcatheter Aortic Valve Implantation | TAVI

Belgium, Greece
RWTH Aachen University

Completed

Vitamin K Supplement for Inhibition of the Progress in Aortic Valve Calcification (08-002)

Aortic Valve Calcification

Germany

Clinical Trials on Aortic Valve Disease

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