Clinical Trials on Arterial Catheterization in South Africa

Total 1347 results

Sanofi Pasteur, a Sanofi Company

Recruiting

Study of a Quadrivalent Meningococcal Conjugate Vaccine (MenACYW Conjugate Vaccine) Given With Routine Pediatric Vaccines in Healthy Infants and Toddlers in India and the Republic of South Africa (MEQ00064)

Healthy Volunteers | Meningococcal Immunisation

South Africa, India
University of Cape Town
London School of Hygiene and Tropical Medicine; Fred Hutchinson Cancer Center; Aurum Institute and other collaborators

Unknown

The Correlate of Risk Targeted Intervention Study (CORTIS)

Tuberculosis

South Africa
Centre for the AIDS Programme of Research in South...
Amsterdam Institute for Global Health and Development; Global Alliance for... and other collaborators

Recruiting

Triage Test for All Oral DR-TB Regimen (TRiAD Study)

Tuberculosis | Drug Resistant Tuberculosis | MDR-TB | XDR-TB

Nigeria, South Africa, Ethiopia
Silence Therapeutics plc

Active, not recruiting

Evaluate SLN360 in Participants With Elevated Lipoprotein(a) at High Risk of Atherosclerotic Cardiovascular Disease Events

Cardiovascular Diseases | Atherosclerosis | Lipoprotein(a)

Australia, Czechia, Denmark, Netherlands, Slovakia, South Africa, United Kingdom
Centers for Disease Control and Prevention

Completed

High Dose Rifapentine Pharmacokinetics, Tolerability and Safety Dosage Rifapentine for Treatment of Tuberculosis (TBTC-29PK)

Smear Positive, Pan-sensitive, Pulmonary Tuberculosis

United States, South Africa, Uganda
Global Alliance for TB Drug Development

Completed

A Phase 2 to Evaluate the Efficacy, Safety and Tolerability of Combinations of Bedaquiline, Moxifloxacin, PA-824 and Pyrazinamide in Adult Subjects With Drug-Sensitive or Multi Drug-Resistant Pulmonary Tuberculosis. (NC-005)

Tuberculosis

Tanzania, South Africa, Uganda
Boston College
Boston University; National Institute of Nursing Research (NINR); National Institutes... and other collaborators

Not yet recruiting

Systems Analysis and Improvement Approach to Prevent TB (SAIA-TB)

Tuberculosis | TB - Tuberculosis | TPT

South Africa
GlaxoSmithKline
Aeras

Completed

Study to Evaluate the Efficacy of GlaxoSmithKline (GSK) Biologicals' Candidate Tuberculosis (TB) Vaccine in Adults

Tuberculosis | Tuberculosis Vaccines

South Africa, Kenya, Zambia
Médecins Sans Frontières, France
Harvard Medical School (HMS and HSDM); Institute of Tropical Medicine, Belgium and other collaborators

Completed

Evaluating Newly Approved Drugs for Multidrug-resistant TB (endTB)

Tuberculosis, Multidrug-Resistant | Infection, Bacterial | Pulmonary Tuberculoses

Pakistan, Georgia, India, Kazakhstan, Lesotho, Peru, South Africa
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Efavirenz (EFV) in HIV-Infected and HIV/Tuberculosis (TB) Coinfected Children

HIV Infections | Tuberculosis

South Africa, Zimbabwe, India, Uganda
Pfizer

Completed

Safety and Immunogenicity of 13-Valent Pneumococcal Conjugate Vaccine (13vPnC) in HIV-Infected Subjects 6 Years of Age or Older Who Are Naive to Pneumococcal Vaccine

HIV Infections | Pneumococcal Infections

South Africa, Romania
Shionogi

Recruiting

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Cefiderocol in Hospitalized Neonates and Infants

Gram-Negative Bacterial Infections

United States, South Africa, Taiwan
Medecins Sans Frontieres, Netherlands
London School of Hygiene and Tropical Medicine; University College, London; University... and other collaborators

Completed

Pragmatic Clinical Trial for a More Effective Concise and Less Toxic MDR-TB Treatment Regimen(s) (TB-PRACTECAL)

Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Extensively Drug-Resistant Tuberculosis

Belarus, South Africa, Uzbekistan
International AIDS Vaccine Initiative
University of Cape Town Lung Institute; European and Developing Countries Clinical... and other collaborators

Active, not recruiting

Study to Evaluate H56:IC31 in Preventing Rate of TB Recurrence

Tuberculosis, Pulmonary

South Africa, Tanzania
National Institute of Allergy and Infectious Diseases...
Otsuka Pharmaceutical Development & Commercialization, Inc.

Recruiting

Evaluating the Pharmacokinetics, Safety, and Tolerability of Delamanid in Combination With Optimized Multidrug Background Regimen (OBR) for Multidrug-Resistant Tuberculosis (MDR-TB) in HIV-Infected and HIV-Uninfected Children With MDR-TB

HIV Infections | Tuberculosis

Tanzania, India, South Africa, Botswana
National Institute of Allergy and Infectious Diseases...

Active, not recruiting

Clofazimine- and Rifapentine-Containing Treatment Shortening Regimens in Drug-Susceptible Tuberculosis: The CLO-FAST Study

HIV | Tuberculosis

Haiti, Zimbabwe, Malawi, South Africa, India
Janssen Research & Development, LLC

Recruiting

Pharmacokinetic Study to Evaluate Anti-mycobacterial Activity of TMC207 in Combination With Background Regimen (BR) of Multidrug Resistant Tuberculosis (MDR-TB) Medications for Treatment of Children/Adolescents Pulmonary MDR-TB

Multidrug-Resistant Tuberculosis

Mozambique, Philippines, Russian Federation, South Africa, Uganda, Ukraine
Michael Hoelscher
Radboud University Medical Center; University College, London; University of...

Recruiting

PanACEA - STEP2C -01

Pulmonary Tuberculosis | Other Specified Pulmonary Tuberculosis

Gabon, South Africa, Tanzania, Malawi, Uganda, Mozambique
Sanofi Pasteur, a Sanofi Company

Completed

Immunogenicity and Safety of an Investigational Quadrivalent Meningococcal Conjugate Vaccine in Healthy Adults, Adolescents, Children, and Toddlers in India and Healthy Adolescents and Children in the Republic of South Africa (MET55)

Healthy Volunteers (Meningococcal Infection)

India, South Africa
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Study of a Single Dose of Pretomanid Added to an Optimized Background Regimen in Children With Rifampicin-Resistant Tuberculosis

Tuberculosis | Rifampicin Resistant Tuberculosis

Brazil, India, South Africa, Tanzania, Thailand
International Maternal Pediatric Adolescent AIDS...
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Not yet recruiting

Safety and Immunogenicity of VPM1002 Vaccination or BCG Revaccination Against TB in Pre-Adolescents Living With and Without HIV in South Africa

HIV Infections | Tuberculosis

South Africa
The Aurum Institute NPC
Johns Hopkins University

Recruiting

Comparing Treatment Completion Of Daily Rifapentine & Isoniazid For One Month (1HP) To Weekly High Dose Rifapentine & Isoniazid For 3 Months (3HP) In Persons Living With HIV and in Household Contacts of Recently Diagnosed Tuberculosis Patients (1 to 3)

Tuberculosis | HIV Seropositivity | Household Contact

South Africa, India, Indonesia, Mozambique
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Active, not recruiting

Evaluating the Pharmacokinetics, Safety, and Tolerability of Bedaquiline in Infants, Children, and Adolescents With Multidrug-Resistant Tuberculosis, Living With or Without HIV

HIV | Tuberculosis

Haiti, India, South Africa
Sanofi

Completed

American-Australian-African Trial With Dronedarone in Patients With Atrial Fibrillation or Atrial Flutter for the Maintenance of Sinus Rhythm (ADONIS)

Atrial Fibrillation | Atrial Flutter

United States, Canada, Argentina, South Africa, Australia
Medecins Sans Frontieres, Netherlands
London School of Hygiene and Tropical Medicine; University of Liverpool; Ministry... and other collaborators

Completed

Economic Evaluation of New MDR TB Regimens (PRACTECAL-EE)

Multi-drug Resistant Tuberculosis | Pulmonary Tuberculoses | Extensively Drug-Resistant Tuberculosis

Belarus, South Africa, Uzbekistan
Ferrer Internacional S.A.

Completed

Efficacy and Safety of Ozenoxacin 1% Cream Versus Placebo in the Treatment of Patients With Impetigo

Impetigo

Germany, South Africa
NovaBay Pharmaceuticals, Inc.

Completed

Vehicle Controlled Efficacy and Safety Study of Two Dose Regimens of CD07223 1.5% Topical Gel in Impetigo

Impetigo

United States, South Africa
HIV Vaccine Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); Biofabri, S.L

Recruiting

Evaluating the Safety and Immunogenicity of MTBVAC in Adolescents and Adults Living With and Without HIV in South Africa (HVTN605A5421)

Tuberculosis | HIV I Infection

South Africa
Prof Gerhard Walzl
London School of Hygiene and Tropical Medicine; Makerere University; Leiden University... and other collaborators

Completed

Evaluation of Host Biomarker-based Point-of-care Tests for Targeted Screening for Active TB (ScreenTB)

Pulmonary Tuberculosis

United Kingdom, Uganda, Ethiopia, Gambia, Germany, Namibia, Netherlands, South Africa
McGill University Health Centre/Research Institute...
King's College London; University of Wisconsin, Madison; University Hospital... and other collaborators

Completed

Breathing-Induced Myocardial Oxygenation Reserve (B-MORE-Pilot)

Coronary Artery Disease

United States, Germany, United Kingdom, Canada, South Africa
Bill & Melinda Gates Medical Research Institute
Wellcome Trust

Completed

Safety and Immunogenicity of a Mycobacterium Tuberculosis Vaccine M72/AS01E in Participants With Well-controlled HIV (MESA-TB)

Human Immunodeficiency Virus

South Africa
IUATLD, Inc
Medical Research Council; Institute of Tropical Medicine, Belgium; Liverpool... and other collaborators

Completed

The Evaluation of a Standard Treatment Regimen of Anti-tuberculosis Drugs for Patients With MDR-TB (STREAM)

MDR-TB

Ethiopia, Georgia, India, Moldova, Republic of, Mongolia, South Africa, Uganda
Foundation for Innovative New Diagnostics, Switzerland
Swiss Tropical & Public Health Institute; University of Cape Town; The HIV Netherlands... and other collaborators

Completed

FujiLAM Prospective Evaluation Trial

Diagnosis of Tuberculosis in People Living With HIV

Malawi, South Africa, Tanzania, Thailand, Uganda, Vietnam, Zambia
University of California, San Francisco
Johns Hopkins University

Not yet recruiting

Program for Rifampicin-Resistant Disease With Stratified Medicine for Tuberculosis (PRISM-TB)

Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Tuberculosis, MDR

Peru, Vietnam, Moldova, Republic of, Mongolia, Pakistan, Philippines, South Africa
Alucent Biomedical

Active, not recruiting

Feasibility Study of the Vessel Restoration System (VRS): ACTIVATE II (ACTIVATEII)

PAD - Peripheral Arterial Disease

Australia
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Terminated

Rifampin-Based Tuberculosis Treatment Versus Rifabutin-Based Tuberculosis Treatment in Persons With HIV

HIV Infection | Tuberculosis

Peru, Brazil, South Africa, Haiti, Kenya
Serum Institute of India Pvt. Ltd.
Vakzine Projekt Management GmbH

Active, not recruiting

Evaluation of Efficacy and Safety of VPM1002 in Comparison to BCG in Prevention of Tb Infection in Infants (VPM1002)

Mycobacterium Tuberculosis Infection

Gabon, Kenya, South Africa, Tanzania, Uganda
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Gentian Violet Vs. Nystatin Oral Suspension for Treatment of Oropharyngeal Candidiasis

HIV-1 Infection

Kenya, Malawi, Uganda, South Africa, Zimbabwe, Botswana, India
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID); National Institute...

Completed

Observational Study of Specificity of Mycobacterium Tuberculosis Screening and Diagnostics in HIV-Infected Individuals

HIV Infections | Tuberculosis

Peru, South Africa, Botswana, Brazil, India, Malawi, Zimbabwe
Alucent Biomedical

Active, not recruiting

Feasibility Study of the Vessel Restoration System (VRS) for the Treatment of Atherosclerotic Lesions in the Superficial Femoral Artery (SFA) and/or Popliteal Artery (PA) After Sub-optimal Percutaneous Transluminal Angioplasty (PTA) or Atherectomy: REACTIVATE I (REACTIVATE I)

PAD - Peripheral Arterial Disease

Australia
McGill University
Canadian Institutes of Health Research (CIHR)

Completed

Rifampin Versus Isoniazid for the Treatment of Latent Tuberculosis Infection in Children (P4v9)

Latent Tuberculosis Infection

Canada, Australia, Benin, Brazil, Ghana, Guinea, Indonesia
Novo Nordisk A/S

Completed

An International Chart Review and Survey for the Prevalence and Clinical Management of Atherosclerotic Cardiovascular Diseases in Patients With Type 2 Diabetes Across Countries in the Middle East and Africa (PACT-MEA)

Diabetes Mellitus, Type 2

Bahrain, Egypt, Jordan, Kuwait, Qatar, South Africa, United Arab Emirates
Global Alliance for TB Drug Development

Completed

Various Doses and Durations of Linezolid Plus Bedaquiline & Pretomanid in Participants With Drug Resistant Tuberculosis (ZeNix)

Tuberculosis | Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Extensively Drug-Resistant Tuberculosis | Tuberculosis, MDR | XDR-TB | Pre-XDR-TB

South Africa, Russian Federation, Georgia, Moldova, Republic of
Cadrock Pty. Ltd.
Centre for Digestive Diseases, Australia

Terminated

Anti-chlamydophila Antibiotic Combination Therapy in the Treatment of Patients With Coronary Heart Disease (ACAC-CHD)

Coronary Heart Disease | Chlamydophila Pneumoniae Infections

Australia
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety of Immediate Versus Deferred Isoniazid Preventive Therapy Among HIV-Infected Pregnant Women

HIV Infections | Tuberculosis

Haiti, South Africa, Thailand, Tanzania, Botswana, Zimbabwe, India, Uganda
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 Followed by PNEUMOVAX™23 in Adults Infected With Human Immunodeficiency Virus (HIV) (V114-018) (PNEU-WAY)

Pneumococcal Infections

United States, France, Peru, South Africa, Thailand
Centers for Disease Control and Prevention
British Medical Research Council

Recruiting

Assessment of the Safety, Tolerability, and Effectiveness of Rifapentine Given Daily for LTBI (ASTERoiD)

Latent Tuberculosis

Australia, United States, Canada, South Africa
Global Antibiotics Research and Development Partnership

Active, not recruiting

Zoliflodacin in Uncomplicated Gonorrhoea

Gonorrhea

United States, Belgium, South Africa, Netherlands, Thailand
Janssen Infectious Diseases BVBA

Completed

TMC207-TiDP13-C208: Anti-bacterial Activity, Safety, and Tolerability of TMC207 in Participants With Multi-drug Resistant Mycobacterium Tuberculosis (MDR-TB).

Tuberculosis

South Africa, Peru, Latvia, Philippines, Russian Federation, Thailand, Brazil, India
Instylla, Inc.

Recruiting

(HALT) Embrace Hydrogel Embolic System (HES) Study of Embolization in Peripheral Arterial Bleeds

Arterial Bleeding in Solid Organs and Peripheral Arteries

United States

Clinical Trials on Arterial Catheterization in South Africa

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