Clinical Trials on Astrocytoma, Oligoastrocytoma, Mixed

Total 2903 results

University of California, San Francisco
Novartis

Terminated

Everolimus With and Without Temozolomide in Adult Low Grade Glioma

Low Grade Glioma | World Health Organization (WHO) Grade II Astrocytomas | Oligodendrogliomas | Mixed Oligoastrocytomas

United States
Washington University School of Medicine

Completed

Evaluation of FDOPA-PET/MRI in Pediatric Patients With CNS Tumors

Glioma | Ganglioglioma | Ganglioneuroma | Astrocytoma, Oligoastrocytoma, Mixed | Glioblastoma Multiforme Glioma

United States
Nicholas Butowski
National Cancer Institute (NCI); Celldex Therapeutics

Terminated

A Study of Varlilumab and IMA950 Vaccine Plus Poly-ICLC in Patients With WHO Grade II Low-Grade Glioma (LGG)

Glioma | Malignant Glioma | Oligodendroglioma | Astrocytoma, Grade II | Glioma, Astrocytic | Oligoastrocytoma, Mixed

United States
Jennie Taylor
University of Minnesota

Active, not recruiting

Neo-adjuvant Evaluation of Glioma Lysate Vaccines in WHO Grade II Glioma

Glioma | Malignant Glioma | Oligodendroglioma | Astrocytoma, Grade II | Glioma, Astrocytic | Oligoastrocytoma, Mixed

United States
INSYS Therapeutics Inc

Completed

Histologic Effect/Safety of Pre/Post-Operative IL13-PE38QQR in Recurrent Resectable Supratentorial Malignant Glioma Patients

Glioblastoma Multiforme | Malignant Glioma | Anaplastic Astrocytoma | Mixed Oligoastrocytoma | Malignant Astrocytoma

United States
INSYS Therapeutics Inc

Completed

Pre-operative IL13-PE38QQR in Patients With Recurrent or Progressive Malignant Glioma

Glioblastoma Multiforme | Malignant Glioma | Anaplastic Astrocytoma | Mixed Oligoastrocytoma

United States, Germany, Israel
INSYS Therapeutics Inc

Completed

Interstitial Infusion of IL13-PE38QQR Cytotoxin in Recurrent Malignant Glioma

Glioblastoma Multiforme | Malignant Glioma | Anaplastic Astrocytoma | Mixed Oligoastrocytoma

United States
Patrick Y. Wen, MD
Massachusetts General Hospital; Dana-Farber Cancer Institute; Brigham and Women... and other collaborators

Terminated

Plerixafor (AMD3100) and Bevacizumab for Recurrent High-Grade Glioma

High Grade Glioma: Glioblastoma (GBM) | High Grade Glioma: Gliosarcoma | Anaplastic Astrocytoma (AA) | Anaplastic Oligodendroglioma (AO) | Mixed Anaplastic Oligoastrocytoma (AOA)

United States
National Cancer Institute (NCI)

Completed

Tandutinib Plus Bevacizumab to Treat Recurrent Brain Tumors

Glioblastoma | Gliosarcoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Anaplastic Mixed Oligoastrocytoma

United States
Washington University School of Medicine

Recruiting

Using MRI-Guided Laser Heat Ablation to Induce Disruption of the Peritumoral Blood Brain Barrier to Enhance Delivery and Efficacy of Treatment of Pediatric Brain Tumors

Glioma | Glioblastoma | Astrocytoma | Anaplastic Astrocytoma | Oligodendroglioma | Pilocytic Astrocytoma | Mixed Oligoastrocytoma | Mixed Glioma | Optic Glioma

United States
Biogen

Completed

Dose Escalation Study to Determine the Safety of IFN-Beta Gene Transfer in the Treatment of Grade III & Grade IV Gliomas

Glioblastoma Multiforme | Gliosarcoma | Anaplastic Astrocytoma | Oligoastrocytoma, Mixed

United States
Teva Branded Pharmaceutical Products R&D, Inc.
National Cancer Institute (NCI)

Terminated

Phase 2 Trial Using Talampanel in Patients With Recurrent High Grade Gliomas

Glioblastoma Multiforme | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Anaplastic Mixed Oligoastrocytoma
Jonsson Comprehensive Cancer Center

Completed

Vaccine for Patients With Newly Diagnosed or Recurrent Low-Grade Glioma

Adult Diffuse Astrocytoma | Adult Mixed Glioma | Adult Oligodendroglioma | Recurrent Adult Brain Tumor | Adult Oligoastrocytoma

United States
Ohio State University Comprehensive Cancer Center

Completed

Temozolomide in Patients With Newly Diagnosed Anaplastic Oligodendroglioma and Mixed Oligoastrocytoma

Anaplastic Oligodendroglioma | Oligoastrocytoma, Mixed

United States
National Cancer Institute (NCI)

Completed

A Randomized Phase II Trial of Vandetanib (ZD6474) in Combination With Carboplatin Versus Carboplatin Alone Followed by Vandetanib Alone in Adults With Recurrent High-Grade Gliomas

Glioblastoma Multiforme | Gliosarcoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Anaplastic Mixed Oligoastrocytoma

United States
INSYS Therapeutics Inc

Completed

Imaging Study of the Distribution of IL13-PE38QQR Infused Before and After Surgery in Adult Patients With Recurrent Malignant Glioma

Glioblastoma Multiforme | Malignant Glioma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Mixed Oligoastrocytoma

United States
Sun Yat-sen University

Unknown

A Phase III Trial on Adjuvant Temozolomide With or Without Interferon-alpha in Newly Diagnosed High-grade Gliomas

Glioblastoma | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma

China
Sun Yat-sen University

Recruiting

A Study on β-elemene as Maintain Treatment for Newly Diagnosed Malignant Gliomas (β-elemene)

Glioblastoma | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma

China
Sun Yat-sen University

Terminated

Treatment Strategy for Low-grade Gliomas

Oligoastrocytoma | Astrocytomas | Oligodendrogliomas

China
OHSU Knight Cancer Institute
Oregon Health and Science University

Completed

Carboplatin, Melphalan, Etoposide Phosphate, Mannitol, and Sodium Thiosulfate in Treating Patients With Previously Treated Brain Tumors

Anaplastic Oligoastrocytoma | Oligoastrocytoma | Anaplastic Oligodendroglioma | Mixed Glioma

United States
National Cancer Institute (NCI)

Completed

Cilengitide in Treating Younger Patients With Recurrent or Progressive High-Grade Glioma That Has Not Responded to Standard Therapy

Childhood High-grade Cerebellar Astrocytoma | Childhood High-grade Cerebral Astrocytoma | Recurrent Childhood Anaplastic Astrocytoma | Recurrent Childhood Anaplastic Oligoastrocytoma | Recurrent Childhood Anaplastic Oligodendroglioma | Recurrent Childhood Cerebellar Astrocytoma | Recurrent Childhood... and other conditions

United States, Canada
University Hospital, Geneva
Bayer

Completed

Sorafenib in Newly Diagnosed High Grade Glioma

Glioblastoma | Gliosarcoma | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma

Switzerland
M.D. Anderson Cancer Center

Recruiting

Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) Glioblastomas

Glioblastoma | Anaplastic Oligoastrocytoma | Oligoastrocytoma | Oligodendroglioma | Anaplastic Oligodendroglioma | WHO Grade III Glioma | Diffuse Astrocytoma, IDH-Wildtype | WHO Grade II Glioma | Anaplastic Astrocytoma, IDH-Wildtype

United States
Erik Mittra
National Cancer Institute (NCI)

Terminated

18F-FDOPA PET/CT or PET/MRI in Measuring Tumors in Patients With Newly-Diagnosed or Recurrent Gliomas

Untreated Childhood Brain Stem Glioma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma | Adult Diffuse Astrocytoma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Adult Oligodendroglioma | Adult Pilocytic Astrocytoma | Adult Pineal Gland Astrocytoma and other conditions

United States
University of Nebraska
National Cancer Institute (NCI)

Terminated

Temozolomide and Ascorbic Acid in Treating Patients With Recurrent High-Grade Glioma

Glioblastoma | Gliosarcoma | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Completed

Vaccine Therapy and Sargramostim in Treating Patients With Malignant Glioma

Glioblastoma | Gliosarcoma | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Giant Cell Glioblastoma | Recurrent Brain Neoplasm | Mixed Glioma

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Carboxylesterase-Expressing Allogeneic Neural Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade Gliomas

Recurrent Glioblastoma | Recurrent Malignant Glioma | Recurrent WHO Grade III Glioma | Recurrent Gliosarcoma | Recurrent Anaplastic Astrocytoma | Recurrent Anaplastic Oligoastrocytoma | Recurrent Anaplastic Oligodendroglioma

United States
Shandong Lanjin Pharmaceuticals Co.,Ltd

Unknown

Safety and Efficacy Study of Intracranially Implanted Carmustine to Treat Newly Diagnosed Malignant Glioma

Glioblastoma | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma

China
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Bafetinib in Treating Patients With Recurrent High-Grade Glioma or Brain Metastases

Adult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Recurrent Adult Brain Tumor | Tumors Metastatic to Brain | Adult Anaplastic Oligoastrocytoma

United States
Sun Yat-sen University

Recruiting

A Phase III Study of Postoperative Early Temozolomide Treatment Plus STUPP Regimen for Newly Diagnosed GBM Multiforme

Glioblastoma | Anaplastic Oligoastrocytoma

China
Tocagen Inc.

Completed

A Study of a Retroviral Replicating Vector Combined With a Prodrug Administered to Patients With Recurrent Malignant Glioma

Glioblastoma | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Multiple Doses of Neural Stem Cell Virotherapy (NSC-CRAd-S-pk7) for the Treatment of Recurrent High-Grade Gliomas

Recurrent Glioblastoma | Recurrent Malignant Glioma | Recurrent WHO Grade III Glioma | Recurrent WHO Grade II Glioma | Recurrent Gliosarcoma | Recurrent Anaplastic Astrocytoma | Recurrent Anaplastic Oligoastrocytoma | Recurrent Anaplastic Oligodendroglioma

United States
Patrick Y. Wen, MD
Massachusetts General Hospital; Boehringer Ingelheim; The Cleveland Clinic; Wake... and other collaborators

Completed

BIBF 1120 for Recurrent High-Grade Gliomas

Glioblastoma | Gliosarcoma | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma

United States
Shandong Lanjin Pharmaceuticals Co.,Ltd

Unknown

Safety and Efficacy Study of Intracranially Implanted Carmustine to Treat Recurrent Malignant Glioma

Glioblastoma | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma

China
Rush University Medical Center
Axelar AB

Terminated

Phase I/II Trial of AXL1717 in the Treatment of Recurrent Malignant Astrocytomas (AXL1717)

Glioblastoma | Gliosarcoma | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Anaplastic Ependymoma | Anaplastic Oligodendroglioma

United States
Tocagen Inc.

Completed

Study of a Retroviral Replicating Vector Given Intravenously to Patients Undergoing Surgery for Recurrent Brain Tumor

Glioblastoma Multiforme | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma

United States
Tocagen Inc.

Completed

Study of a Retroviral Replicating Vector Combined With a Prodrug to Treat Patients Undergoing Surgery for a Recurrent Malignant Brain Tumor

Glioblastoma Multiforme | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma

United States
Maastricht Radiation Oncology

Withdrawn

Re-irradiation of High Grade Gliomas: a Quality of Life Study

Glioblastoma Multiforme | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma

Netherlands
Northwestern University
National Cancer Institute (NCI)

Completed

Neural Stem Cell Based Virotherapy of Newly Diagnosed Malignant Glioma

Glioma | Brain Cancer | Glioblastoma Multiforme | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Astrocytoma, Grade III | Astrocytoma, Grade IV

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Terminated

Oncolytic HSV-1716 in Treating Younger Patients With Refractory or Recurrent High Grade Glioma That Can Be Removed By Surgery

Recurrent Childhood Anaplastic Astrocytoma | Recurrent Childhood Anaplastic Oligoastrocytoma | Recurrent Childhood Anaplastic Oligodendroglioma | Recurrent Childhood Giant Cell Glioblastoma | Recurrent Childhood Glioblastoma | Recurrent Childhood Gliomatosis Cerebri | Recurrent Childhood Gliosarcoma

United States
City of Hope Medical Center

Completed

A Pilot Feasibility Study of Oral 5-Fluorocytosine and Genetically-Modified Neural Stem Cells Expressing E.Coli Cytosine Deaminase for Treatment of Recurrent High Grade Gliomas

Recurrent High Grade Glioma | Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Recurrent Adult Brain Tumor | Recurrent Grade III Glioma | Adult Brain Tumor | Recurrent Grade IV Glioma | Adult Anaplastic...

United States
Neuro-Oncology Working Group of the German Cancer...
Charite University, Berlin, Germany; University of Zurich; University Hospital... and other collaborators

Completed

Randomized Phase III Study of Sequential Radiochemotherapy of Anaplastic Glioma With PCV or Temozolomide (NOA-04)

Oligoastrocytoma | Anaplastic Astrocytoma | Oligodendroglioma

Germany
Alaunos Therapeutics

Completed

A Study of Ad-RTS-hIL-12 With Veledimex in Subjects With Glioblastoma or Malignant Glioma

Glioblastoma Multiforme | Anaplastic Oligoastrocytoma

United States
Huashan Hospital

Unknown

Study About the Validity of MRS-guided Resection on Prognosis High-grade Glioma Gliomas

Glioma | Anaplastic Oligoastrocytoma | Glioblastomas (GBM)
National Cancer Institute (NCI)

Terminated

Eligibility Screening of Patients With Central Nervous System Tumors for the National Cancer Institute s (NCI) Clinical Research Protocols

Gliosarcoma | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Oligodendroglioma | Glioblatoma

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Genetically Modified Neural Stem Cells, Flucytosine, and Leucovorin for Treating Patients With Recurrent High-Grade Gliomas

Anaplastic Oligoastrocytoma | Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
NRG Oncology
National Cancer Institute (NCI)

Active, not recruiting

Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma

Glioma | Oligoastrocytoma | Anaplastic Astrocytoma | Oligodendroglioma | Diffuse Astrocytoma | WHO Grade III Glioma | IDH2 Gene Mutation | IDH1 Gene Mutation | 1p/19q Co-deletion

United States
Dartmouth-Hitchcock Medical Center

Recruiting

Evaluating the Expression Levels of MicroRNA-10b in Patients With Gliomas

Glioblastoma | Astrocytoma | Brain Cancer | Anaplastic Oligoastrocytoma | Oligoastrocytoma | Anaplastic Astrocytoma | Oligodendroglioma | Brain Tumors | Anaplastic Oligodendroglioma

United States
National Cancer Institute (NCI)

Completed

Vorinostat and Radiation Therapy Followed by Maintenance Therapy With Vorinostat in Treating Younger Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma

Gliosarcoma | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma

United States, Canada, Australia
Istari Oncology, Inc.
Duke University; Solving Kids' Cancer; The Andrew McDonough B+ Foundation

Completed

Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Children

Glioblastoma | Malignant Glioma | Gliosarcoma | Ependymoma | Medulloblastoma | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Atypical Teratoid/Rhabdoid Tumor of Brain | Pleomorphic Xanthoastrocytoma of Brain | Embryonal Tumor of Brain

United States

Clinical Trials on Astrocytoma, Oligoastrocytoma, Mixed

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