Clinical Trials on BCLC Stage C HCC

Total 297 results

Vertex Pharmaceuticals Incorporated
Duke Clinical Research Institute; ViroChem Pharma

Completed

Safety,Tolerability and Pharmacokinetics of Multiple Ascending Doses of VCH 916 in Subjects With Chronic Hep C Infection

HCV Infection

Puerto Rico, United States, Canada
University Hospital, Strasbourg, France

Unknown

Study of the Role of Dendritic Cells in the Recurrence of Hepatitis C After Liver Transplantation. Analysis of Hepatitis C Virus (HCV) Quasispecies Evolution.

HCV Infection

France
Dr.Waleed Samir

Unknown

Impact of IL-28B rs12979860 and rs4803217 Gene Polymorphisms Associated With miRNAs Deregulation on HCV-related Hepatocellular Carcinoma

HCV Infection ( Genotype 4)

Egypt
Gilead Sciences

Completed

Sofosbuvir/Velpatasvir in Adults With Chronic Hepatitis C Virus Infection Who Are on Dialysis for End Stage Renal Disease (SOF/VEL ESRD)

Chronic Hepatitis C

Israel, United Kingdom, Australia, Spain, Canada, New Zealand
Henan Cancer Hospital

Recruiting

Alotinib Plus Durvalumab-Platinum-Etoposide in First-line Treatment Extensive Small-cell Lung Cancer

SCLC, Extensive Stage

China
David Bond, MD
Bristol-Myers Squibb

Active, not recruiting

Nivolumab With DA-REPOCH Chemotherapy Regimen in Treating Patients With Aggressive B-Cell Non-Hodgkin's Lymphoma

Diffuse Large B-Cell Lymphoma | Aggressive Non-Hodgkin Lymphoma | Indolent Non-Hodgkin Lymphoma | Ann Arbor Stage IV B-Cell Non-Hodgkin Lymphoma | High Grade B-Cell Lymphoma, Not Otherwise Specified | Transformed Non-Hodgkin Lymphoma | Ann Arbor Stage II B-Cell Non-Hodgkin Lymphoma | Ann Arbor Stage... and other conditions

United States
Icahn School of Medicine at Mount Sinai

Completed

Impact of Interferon-free Treatment for Hepatitis C Virus (HCV) on Blood Cells and Factors in Blood

Hepatitis C | HCV | Liver Transplant

United States
Gilead Sciences

Completed

Safety, Tolerability, and Antiviral Activity of 24 or 48 Weeks of GS-9190 in Combination With Peginterferon Alfa 2a and Ribavirin for the Treatment of Genotype-1 Chronic HCV Infection

HCV Infection

United Kingdom, Germany, Ireland, United States, Belgium, Puerto Rico, Poland
French National Agency for Research on AIDS and...
Merck Sharp & Dohme LLC

Completed

Efficacy of PegInterferon-Ribavirin-Boceprevir Therapy in Patients Infected With G1 HCV With Cirrhosis, Awaiting Liver Transplantation

HCV Infection | Liver Cirrhosis, Experimental

France
City University of New York, School of Public Health
National Institute on Drug Abuse (NIDA); Weill Medical College of Cornell University and other collaborators

Completed

Accessible HCV Care Intervention for People Who Inject Illicit Drugs (PWID)

Hepatitis C | HCV Coinfection | People Who Inject Drugs | PWID

United States
University Hospital, Montpellier

Completed

ST2 for the Management of Heart Failure - STADE-HF (STADE-HF)

Heart Failure | Diastolic Heart Failure | Systolic Heart Failure Stage C

France
MassBiologics

Terminated

Study in Hepatitis C Virus (HCV) Infected Patients Undergoing Liver Transplantation to Evaluate a Human Monoclonal Antibody Against Hepatitis C (MBL-HCV1)

Liver Transplantation | HCV Infection

United States
AbbVie

Completed

Efficacy and Safety of Glecaprevir/Pibrentasvir (ABT-493/ABT-530) in Treatment-Naive and Treatment-Experienced Asian Adults With Chronic Hepatitis C Virus Genotype (GT) 1 to GT6 Infection With Compensated Cirrhosis and With or Without Human Immunodeficiency Virus Co-Infection (VOYAGE-2)

Hepatitis C Virus (HCV)

China, Korea, Republic of
Liver Institute of Virginia
Merck Sharp & Dohme LLC; Chronic Liver Disease Foundation

Unknown

A Pilot Study to Treat Patients With Chronic Hepatitis C Virus (HCV) Genotype 1 and End-Stage Renal Disease (ESRD)

End Stage Renal Disease | Chronic Hepatitis C

United States
National Taiwan University Hospital

Completed

Interferon Treatment for Patients With Chronic Hepatitis C and End Stage Renal Disease

End Stage Renal Disease | Chronic Hepatitis C

Taiwan
Theravance Biopharma

Completed

TD-6450 MAD Study in HCV Infected Subjects

Hepatitis C | HCV

United States
Gilead Sciences

Completed

Efficacy and Safety of Sofosbuvir/Ledipasvir Fixed-Dose Combination ± Ribavirin in Cirrhotic Subjects With Chronic Genotype 1 HCV Infection

HCV Infection

France
Hoffmann-La Roche

Completed

Safety, Tolerability, and Antiviral Activity of ANA598 Administered in Combination With Pegylated Interferon and Ribavirin for the Treatment of Genotype-1 Chronic HCV Infection

HCV Infection

United States, Puerto Rico
Benha University

Completed

Effect of New Oral Treatment for Hepatitis C Virus on Seminal Parameters

Male Infertility | HCV

Egypt
Joel Neal
Nektar Therapeutics

Completed

Phase 2 Etirinotecan Pegol in Refractory Brain Metastases & Advanced Lung Cancer / Metastatic Breast Cancer

Tumors Metastatic to Brain | Stage IV Non-small Cell Lung Cancer (NSCLC) | Recurrent Non-small Cell Lung Cancer (NSCLC) | Extensive-stage Small Cell Lung Cancer (SCLC) | Recurrent Small Cell Lung Cancer (SCLC) | Metastatic Breast Cancer (mBC)

United States
Gilead Sciences

Completed

Efficacy and Safety Study of GS-9256 and GS-9190 Alone and in Combination With Ribavirin for 28 Days in Patients With Chronic Hepatitis C Virus Infection

HCV Infection

Germany, Belgium, United Kingdom, France
Aethlon Medical Inc.

Terminated

Safety Study of the Aethlon Hemopurifier (AEMD-IDE-20)

End Stage Renal Disease | Hepatitis C Infection

United States
National Liver Institute, Egypt

Unknown

Safety and Efficacy Study of CENV3 Vaccine to Protect Against HCV Infection (CENV3)

Vaccine Overdose of Undetermined Intent

Egypt
Hebei Medical University Fourth Hospital

Recruiting

Durvalumab Combined With Chemoradiotherapy for Limited Stage Small Cell Lung Cancer (Camel-01)

SCLC, Limited Stage

China
Peking University Cancer Hospital & Institute

Recruiting

Molecular Subtyping of Extensive Stage Small Cell Lung Cancer and Relevent Clinical Significance (MOSAIC)

SCLC,Extensive Stage

China
Tianjin Medical University Cancer Institute and...

Recruiting

Study of DLL3-CAR-NK Cells in the Treatment of Extensive Stage Small Cell Lung Cancer

SCLC, Extensive Stage

China
Kirby Institute

Active, not recruiting

Control and Elimination Within Australia of Hepatitis C From People Living With HIV (CEASE)

Hepatitis C | HIV | HIV-HCV Coinfection

Australia
Gilead Sciences

Completed

Efficacy, Safety, and Tolerability of Ledipasvir/Sofosbuvir (LDV/SOF) Treatment for HIV/HCV Co-infected Participants Who Switch to Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (E/C/F/TAF) or Emtricitabine/Rilpivirine/Tenofovir Alafenamide (F/R/TAF) Prior to LDV/SOF HCV Treatment (Co-STARs)

HIV-1 Infection | HCV Infection

United States, Puerto Rico
Radboud University Medical Center
Merck Sharp & Dohme LLC

Completed

Pharmacokinetic Study of the HCV Protease Inhibitor Boceprevir and the HIV Integrase Inhibitor Raltegravir (OPAL)

HIV Infections | HCV Infections

Netherlands
University of Florida
AbbVie; University of North Carolina, Chapel Hill

Completed

Multi-Center, Randomized, Open-Label Study of G/P +/- RBV for NS5A + SOF Previously Treated GT1 HCV Subjects

Hepatitis C | HCV

United States
Beth Israel Deaconess Medical Center

Completed

Quality of Life Therapy for Adults With Hepatitis C Virus and Cirrhosis Awaiting Liver Transplantation

Chronic HCV

United States
Columbia University
Merck Sharp & Dohme LLC

Withdrawn

Boceprevir in End Stage Renal Disease (ESRD)

End Stage Renal Disease | Hepatitis C Infection
Mansoura University Children Hospital

Unknown

Chronic Hepatitis C Treatment in Egyptian Children With Gaucher Disease.

HCV | Gaucher Disease

Egypt
Henan Cancer Hospital

Recruiting

Utidelone in Third-line and Above Treatment of Small Cell Lung Cancer

SCLC, Extensive Stage

China
Third Military Medical University

Recruiting

Toripalimab Combined With Anlotinib, Etoposide and Platinum in the Treatment of Extensive-stage Small Cell Lung Cancer

Small Cell Lung Cancer | Lung Cancer | SCLC, Extensive Stage

China
St. Louis University

Suspended

Bariatric Embolization of Arteries in Obese Patients With HCC to Allow Salvage Liver Transplantation

Obesity | HCC | Body Weight | Hepatocellular Carcinoma | Hepatitis C | Weight Loss | Cirrhosis

United States
Fudan University

Recruiting

WBRT With Hippocampal-avoidance Technique Followed by SRT for Extensive-stage SCLC With Baseline Brain Metastases

Brain Metastases | SCLC,Extensive Stage

China
Gilead Sciences

Completed

Pharmacokinetics of Voxilaprevir in Adults With Normal Renal Function and Severe Renal Impairment

HCV Infection

United States, New Zealand, Germany
Sidney Kimmel Comprehensive Cancer Center at Johns...

Completed

Hippocampal Prophylactic Cranial Irradiation for Small Cell Lung Cancer

SCLC | Small-cell Lung Cancer | Small Cell Lung Cancer Limited Stage

United States
Akeso
Chipscreen Biosciences, Ltd.

Active, not recruiting

A Study of AK104 in Combination With Chiauranib in Patients With Extensive Stage Small Cell Lung Cancer

SCLC,Extensive Stage

Australia, China
Hoffmann-La Roche

Completed

HELPS Study - A Study of Peginterferon Alfa-2a (Pegasys) in Patients With Chronic Hepatitis C (CHC) and End-Stage Renal Disease (ESRD)

Hepatitis C, Chronic

France, Greece, Austria, Turkey, United Arab Emirates, Brazil, Italy, Indonesia
Tibotec Pharmaceuticals, Ireland

Completed

TMC435350-TiDP16-C105: Phase I, 3-way Crossover, Drug-drug Interaction Between TMC435350 and Rifampin After Multiple Dosing.

Hepatitis C | Tuberculosis | Pharmacokinetics | HCV | Rifampin
Icahn School of Medicine at Mount Sinai
National Institute on Drug Abuse (NIDA)

Recruiting

Persuasive Health Communication Intervention for HIV/HCV

Human Immunodeficiency Virus (HIV) | Hepatitis C (HCV)

United States
Massachusetts General Hospital

Terminated

DAA Treatment in Donor HCV-positive to Recipient HCV-negative Liver Transplant

End Stage Liver Disease | Hepatitis C

United States
Gilead Sciences

Completed

Sofosbuvir Plus Ribavirin, or Ledipasvir/Sofosbuvir in Adults With HCV Infection and Renal Insufficiency

HCV Infection

New Zealand, United States, Puerto Rico
Shanghai Junshi Bioscience Co., Ltd.

Recruiting

Phase 3 Study of Toripalimab Alone or in Combination With Tifcemalimab as Consolidation Therapy in Patients With Limited-stage Small Cell Lung Cancer (LS-SCLC)

Limited-stage Small Cell Lung Cancer (LS-SCLC)

China, France, United States, Spain, Taiwan, Korea, Republic of, Turkey, Italy, Netherlands, Georgia, Germany, Belgium, Poland, Romania
Memorial Sloan Kettering Cancer Center

Recruiting

A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancer

Melanoma | Solid Tumor | Metastatic Cancer | Advanced Cancer | Head and Neck Squamous Cell Carcinoma | Kaposi Sarcoma | Merkel Cell Carcinoma | Angiosarcoma | Basal Cell Carcinoma | Extramammary Paget Disease | HNSCC | Refractory Cancer | Cutaneous Squamous Cell Carcinoma | BCC | Adnexal Carcinoma | BCC - Basal Cell Carcinoma and other conditions

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Prepare to Care, A Supported Self-Management Intervention for Head and Neck Cancer CaregiversHead and Neck Cancer

Recurrent Head and Neck Squamous Cell Carcinoma | Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Caregiver | Salivary Gland Squamous Cell Carcinoma | Malignant Head and Neck Neoplasm | Recurrent Lip and Oral Cavity Squamous Cell Carcinoma | Stage... and other conditions

United States
Hirva Mamdani
AstraZeneca; Barbara Ann Karmanos Cancer Institute

Recruiting

MOnaliZumab in Combination With durvAlumab (MEDI4736) Plus Platinum-based chemotheRapy for First-line Treatment of Extensive Stage Small Cell Lung Cancer (MOZART)

Small Cell Lung Cancer | SCLC | Extensive Stage Small Cell Lung Cancer

United States
Fondazione Policlinico Universitario Agostino Gemelli...
Istituto Di Ricerche Farmacologiche Mario Negri; Foundation Medicine

Recruiting

Carboplatin-Paclitaxel-Bevacizumab vs Carbo-Pacli-Beva-Rucaparib vs Carbo-Pacli-Ruca, Selected According to HRD Status, in Patients With Advanced Ovarian, Primary Peritoneal and Fallopian Tube Cancer, Preceded by a Phase I Dose Escalation Study on Ruca-Beva Combination (MITO25)

Advanced (Stage IIIB-C-IV) Ovarian, Primary Peritoneal and Fallopian Tube Cancer

Italy

Clinical Trials on BCLC Stage C HCC

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Egypt

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Drug Interventions

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