Clinical Trials on Bacterial Infections Respiratory

Total 101040 results

Armata Pharmaceuticals, Inc.

Recruiting

Study to Evaluate the Safety, Phage Kinetics, and Efficacy of Inhaled AP-PA02 in Subjects With Non-Cystic Fibrosis Bronchiectasis and Chronic Pulmonary Pseudomonas Aeruginosa Infection (Tailwind)

Pseudomonas Aeruginosa | Lung Infection | Non-cystic Fibrosis Bronchiectasis

United States
Pfizer

Completed

Safety and Immunogenicity Study of 20vPnC When Coadministered With a Booster Dose of BNT162b2

COVID-19 | Pneumococcal Disease | SARS-CoV-2 Infection

United States
Pfizer

Terminated

Study Evaluating Safety and Efficacy of Tigecycline Versus Imipenem/Cilastatin Subjects With Hospital-Acquired Pneumonia

Pneumonia, Bacterial

Canada, United States, Argentina, Australia, Brazil, Chile, Colombia, Croatia, France, Hungary, Korea, Republic of, Latvia, Russian Federation, Taiwan
University of Ulsan
Ulsan University Hospital

Completed

Clinical Analysis of the Patients With Cavitary Pulmonary TB and Endobronchial TB in the PPM-UUH Cohort

Tuberculosis | Tuberculosis, Pulmonary | Multi-drug Resistant Tuberculosis | Bronchoscopy | Transmission | Cavity | Acid Fast Bacilli Infection | Insolation

Korea, Republic of
Shionogi

Terminated

Cefiderocol Concentrations in the Lungs of Hospitalized Patients With Bacterial Pneumonia

Bacterial Pneumonia

United States
ARCIM Institute Academic Research in Complementary...

Completed

Managing Bacterial Pneumonia in Children Without Antimicrobials

Pneumonia

Germany
Assistance Publique - Hôpitaux de Paris

Unknown

Multiplex Polymerase Chain Reaction in Postoperative Pneumonia After Thoracic Surgery (POP-PCR)

Pneumonia | Bacterial Pneumonia

France
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Tigecycline Versus Imipenem/Cilastatin in Hospital-Acquired Pneumonia

Bacterial Pneumonia

United States
Novartis Vaccines

Completed

Study in Infants (6-12 Months) Comparing Two Doses of a Monovalent Glycoprotein-Conjugated (Diptheria Toxin -CRM197) Vaccine Versus a Tetanus Toxoid-Conjugated Vaccine Available for the Prevention of Haemophilus Influenzae Type b Infections in China

Haemophilus Influenzae Type b (Hib) Infection

China
Evopoint Biosciences Inc.

Recruiting

Evaluation of the Efficacy and Safety of Intravenous Imipenem/Cilastatin/XNW4107 in Comparison With Recarbrio in Adults With HABP /VABP (REITAB-2)

Hospital Acquired Bacterial Pneumonia or Ventilator-Associated Bacterial Pneumonia

United States, Spain, France, Israel
Merck Sharp & Dohme LLC

Completed

Imipenem/Cilastatin/Relebactam (MK-7655A) Versus Piperacillin/Tazobactam in Participants With Hospital-Acquired or Ventilator-Associated Bacterial Pneumonia (MK-7655A-016)

Hospital-Acquired Bacterial Pneumonia | Ventilator-Associated Bacterial Pneumonia

Mexico, Brazil, China, France, Philippines, Romania, Russian Federation, Ukraine
Hospices Civils de Lyon

Completed

Teicoplanin-based Antimicrobial Therapy in Staphylococcus Aureus Bone and Joint Infection: Tolerance, Efficacy and Experience With Subcutaneous Administration

Staphylococcus Aureus | Bone and Joint Infection | Teicoplanin-based Antimicrobial Therapy

France
Washington University School of Medicine

Completed

Individualized vs. Household MRSA Decolonization (HOME2DS)

Staphylococcal Skin Infection | Abscess | Furunculosis | Staphylococcus Aureus | MRSA Infection

United States
Aaron Chen
Johns Hopkins University; Thrasher Research Fund

Completed

Comparison of Cephalexin Versus Clindamycin for Suspected CA-MRSA Skin Infections

Staphylococcal Skin Infection | Abscess | Staphylococcal Infection | Folliculitis

United States
Savara Inc.

Completed

Pilot Trial of Inhaled Molgramostim in Nontuberculous Mycobacterial (NTM) Infection (OPTIMA)

Mycobacterium Infections, Nontuberculous

Australia, United Kingdom
Cumberland Pharmaceuticals

Completed

Phase 2 Trial of TD 6424 (Telavancin) Versus Standard Therapy for Complicated Gram Positive Skin and Skin Structure Infections (Gram Positive cSSSI) (FAST)

Burns | Ulcer | Abscess | Cellulitis | Wound Infections | Infections, Gram-Positive Bacterial

United States
University of Pittsburgh
Elan Pharmaceuticals

Completed

Pharmacodynamic Parameters of Two Different Doses of Cefepime

Pneumonia | Bacteremia | Infection

United States
TD Vaccines A/S
Johns Hopkins University; University of Vermont; SNBL Clinical Pharmacology Center... and other collaborators

Unknown

ACE393-103 Vaccination Challenge Study (ACE393-103VC)

Campylobacter Infection

United States
University Hospital, Brest

Unknown

Intensive Care Unit Acquired Infections in Patients Colonized With Extended Spectrum Enterobacteriaceae (BMREA)

Bacteremia | Enterobacteriaceae Infections | Ventilator Associated Pneumonia | Abdominal Infection

France
Melinta Therapeutics, Inc.

Completed

Safety and Efficacy Study of Oxazolidinones to Treat Uncomplicated Skin Infections

Streptococcal Infections | Abscess | Staphylococcal Skin Infections | Infectious Skin Diseases | Bacterial Skin Diseases

United States
Beijing Minhai Biotechnology Co., Ltd

Unknown

Safety and Immunogenicity of Haemophilus Influenzae Type b Conjugate Vaccine，Freeze-dried

Haemophilus Influenzae Type b Infections

China
Sir Run Run Shaw Hospital
University of Birmingham

Unknown

Gram-negative Bacilli and MRSA Screening in ICU in China

Infections, Bacterial

China
GlaxoSmithKline

Completed

Relative Bioavailability, Safety, Tolerability, Pharmacokinetics (PK) and Food Effect Study of GSK2140944 in Healthy Subjects

Infections, Bacterial

United States
GlaxoSmithKline

Completed

A Randomized, Single Blind, Placebo Controlled Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Single Oral Doses and Repeat Escalating Oral Doses of GSK2251052 in Healthy Adult Subjects

Infections, Bacterial

Australia
GlaxoSmithKline

Completed

Single Dose Escalation First Time in Human PK Study

Infections, Bacterial

Australia
GlaxoSmithKline

Completed

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Oral and Intravenous GSK1322322 in Healthy Subjects

Infections, Bacterial

United States
GlaxoSmithKline

Completed

To Evaluate Plasma and Pulmonary Pharmacokinetics of GSK2140944

Infections, Bacterial

United States
GlaxoSmithKline

Completed

A Study to Assess the Relative Bioavailability of Three Formulations and Food Effect on GSK1322322 in Healthy Subjects

Infections, Bacterial

United States
GlaxoSmithKline

Completed

Retapamulin Ointment in Healthy Adults Nasally Colonized With Staphylococcus Aureus

Infections, Bacterial

United States
GlaxoSmithKline

Withdrawn

A Single Center Four Part Study in Healthy Adult Subjects to Evaluate: the Safety, Tolerability and Pharmacokinetics of a Single Oral Dose and Repeat Escalating Oral Doses of GSK945237; the Effect of Linezolid on Hematology Safety Parameters; and the Effects of GSK945237 and Moxifloxacin on QTc.

Infections, Bacterial
GlaxoSmithKline

Withdrawn

A Study to Evaluate the Effect of GSK1322322 on Cardiac Conduction as Assessed by 12-lead Electrocardiogram in Healthy Volunteers

Infections, Bacterial
King Faisal University

Suspended

In Vitro Activity of Tigecycline Among Key Bacterial Pathogens Exhibiting Multidrug Resistance

Infections, Bacterial

Saudi Arabia
Seoul National University Bundang Hospital

Recruiting

The Efficacy of the 7 Days Tailored Therapy as the 1st Eradication of H. Pylori Infection

Helicobacter Infection

Korea, Republic of
Seoul National University Bundang Hospital

Terminated

The Efficacy of the 7 Days Tailored Therapy as 2nd Rescue Therapy for Eradication of H. Pylori Infection

Helicobacter Infection

Korea, Republic of
Global Alliance for TB Drug Development

Completed

A Phase 1, Drug-Drug Interaction Study of TBAJ-876 in Healthy Adults

Tuberculosis | Tuberculosis, Pulmonary | Pulmonary Disease | Multi Drug Resistant Tuberculosis | Drug Sensitive Tuberculosis | Drug-resistant Tuberculosis | Mycobacterium Tuberculosis Infection

United States
Global Alliance for TB Drug Development

Completed

Evaluate Safety, Tolerability, PK of TBAJ-876 in Healthy Adults

Tuberculosis | Tuberculosis, Pulmonary | Pulmonary Disease | Multi Drug Resistant Tuberculosis | Drug Sensitive Tuberculosis | Drug-resistant Tuberculosis | Mycobacterium Tuberculosis Infection

United States
Midwest Pulmonary and Critical Care
Genentech, Inc.

Completed

Efficacy and Safety of Activase (Ateplase) vs Placebo in Complicated Pleural Effusions (CPE)/Empyemas (CPE)

Pleural Effusion Associated With Pulmonary Infection | Bacterial Pleural Effusion Other Than Tuberculosis

United States
Aga Khan University

Unknown

Efficacy Study of Community-Based Treatment of Serious Bacterial Infections in Young Infants

Sepsis | Bacterial Infection | Infant, Newborn

Pakistan
Anbics Management-Services Ag
Swiss National Science Foundation

Terminated

Azithromycin as a Quorum-Sensing Inhibitor for the Prevention of Pseudomonas Aeruginosa Ventilator-Associated Pneumonia

Pneumonia, Ventilator-Associated | Pseudomonas Infections

Belgium, Former Serbia and Montenegro, France, Poland, Spain, Switzerland
Paratek Pharmaceuticals Inc

Completed

Omadacycline vs Moxifloxacin for the Treatment of CABP (EudraCT #2013-004071-13)

Bacterial Pneumonia | Community-Acquired Infections

United States, Belgium, Brazil, Bulgaria, Croatia, Czechia, Georgia, Germany, Greece, Hungary, Israel, Korea, Republic of, Latvia, Mexico, Peru, Philippines, Poland, Romania, Russian Federation, Slovakia, South Africa, Spain, Taiwan, ... and more
Wockhardt
ACM

Completed

Phase II Study of Oral Nafithromycin in CABP

Community-Acquired Bacterial Pneumonia (CABP)

United States
Furiex Pharmaceuticals, Inc

Terminated

Efficacy and Safety Study of JNJ-32729463 Compared With Moxifloxacin for the Treatment of Subjects Requiring Hospitalization for Community-Acquired Bacterial Pneumonia

Community-Acquired Bacterial Pneumonia (CABP)

United States, Canada, Colombia, Germany, Hungary, Poland
GlaxoSmithKline

Completed

Retapamulin Microdialysis Feasibility Study

Skin Infections, Bacterial

United States
GlaxoSmithKline

Completed

Retapamulin Versus Placebo in Secondarily-Infected Traumatic Lesions (SITL)

Skin Infections, Bacterial

United States, South Africa, India, Argentina, Brazil
GlaxoSmithKline

Completed

ALTARGO(Retapamulin) PMS(Post-marketing Surveillance) (ALTARGOPMS)

Skin Infections, Bacterial

Korea, Republic of
GlaxoSmithKline

Completed

United States Pharmacovigilence Retapamulin-Prescribing

Skin Infections, Bacterial
The University of Texas Health Science Center at...
Pfizer

Completed

Use of Azithromycin and Rifabutin Administered 3 Times Weekly for the Treatment of M. Avium Complex (MAC) Lung Disease

Mycobacterium Avium Complex

United States
National Taiwan University Hospital

Completed

Program Cell Death Receptor 1 in Mycobacterium Avium Complex Lung Disease

Mycobacterium Avium

Taiwan
Paratek Pharmaceuticals Inc

Active, not recruiting

Oral Omadacycline vs. Placebo in Adults With NTM Pulmonary Disease Caused by Mycobacterium Abscessus Complex (MABc)

Mycobacterium Infections, Nontuberculous | Nontuberculous Mycobacterial Lung Disease | Mycobacterium Abscessus Infection | Nontuberculous Mycobacterial Pulmonary Infection

United States
Bayer

Terminated

Sivextro in Acute Bacterial Skin and Skin Structure Infection (ABSSSI) in Hospitalized Patients. A Global Observational Study (DART)

Skin Disease, Infectious

Russian Federation, Mexico, Singapore

Clinical Trials on Bacterial Infections Respiratory

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