Clinical Trials on Benign or Malignant Liver and Bile Duct Disease in France

Total 208 results

Hospital St. Joseph, Marseille, France

Unknown

Assessment of Cholangio-pancreatoscopy for the Diagnosis and the Treatment of Biliary and Pancreatic Diseases

Biliary Tract Diseases | Common Bile Duct Diseases | Pancreatic Duct Disorder | Lesions of Biliary or Wirsung Ducts

France
European Organisation for Research and Treatment...

Terminated

Radiation Therapy and Fluorouracil Before Surgery in Treating Patients With Primary or Recurrent Bile Duct Cancer

Liver Cancer | Extrahepatic Bile Duct Cancer

France, United States, Belgium
Nantes University Hospital

Unknown

in Vivo TICE (TransIntestinal Cholesterol Excretion) (in vivoTICE)

Occlusion of Bile Duct With an External Bile Diversion.

France
Federation Francophone de Cancerologie Digestive

Completed

Fluorouracil, Cisplatin, and Radiation Therapy or Gemcitabine and Oxaliplatin in Treating Patients With Nonmetastatic Biliary Tract Cancer That Cannot Be Removed By Surgery

Liver Cancer | Gallbladder Cancer | Extrahepatic Bile Duct Cancer

France
National Cancer Institute (NCI)

Terminated

Cediranib Maleate and Combination Chemotherapy in Treating Patients With Advanced Biliary Cancers

Advanced Adult Primary Liver Cancer | Localized Unresectable Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer | Recurrent Extrahepatic Bile Duct Cancer | Recurrent Gallbladder Cancer | Unresectable Extrahepatic Bile Duct Cancer | Unresectable Gallbladder Cancer | Cholangiocarcinoma... and other conditions

United States
University Hospital, Bordeaux

Completed

LaPAroscopic Low pRessure cOlorectal Surgery (PAROS)

Malignant or Benign Pathology

France
Boston Scientific Corporation

Completed

Study of the WallFlex™ Biliary Partially-covered Stent for the Palliative Treatment of Malignant Bile Duct Obstruction

Biliary Strictures Caused by Malignant Neoplasms

Italy, Belgium, France, Germany, India, Netherlands
University Hospital, Bordeaux

Recruiting

Low Impact Laparoscopic in Colorectal Resection - PAROS2 (PAROS2)

Malignant or Benign Pathology

France
Beaujon Hospital

Unknown

Reconstruction of the Bile Duct With the Round Ligament

Bile Duct Obstruction, Extrahepatic

France
Institut Paoli-Calmettes

Completed

Prospective Evaluation of the Ablation Therapy With Bipolar Radio Frequency for Nonresectable Bile Duct Cancer (RFA-BILIAIRE)

Nonresectable Bile Duct Cancer

France
Assistance Publique Hopitaux De Marseille

Completed

Endoscopic Gastroenteric Anastomosis With New Tissue Apposing Stent in the Management of Antro-pyloroduodenal Obstruction : Evaluation of Feasibility, Efficacy and Tolerance.

Antro-pyloric and/or Duodenal Benign or Malignant Obstructions

France
UNICANCER

Completed

Gemcitabine Hydrochloride and Oxaliplatin or Observation in Treating Patients With Biliary Tract Cancer That Has Been Removed by Surgery

Liver Cancer | Gallbladder Cancer | Extrahepatic Bile Duct Cancer

France
Mirum Pharmaceuticals, Inc.

Active, not recruiting

MRX-800: A Long-Term Safety Study of Maralixibat in the Treatment of Cholestatic Liver Disease in Subjects Who Previously Participated in a Maralixibat Study (MERGE)

Cholestatic Liver Disease

United States, France, United Kingdom, Canada, Belgium, Poland, Australia, Spain
National Cancer Institute (NCI)

Active, not recruiting

Testing A New Combination of Anti-cancer Immune Therapies, Atezolizumab and CDX-1127 (Varlilumab) With or Without the Addition of a Third Anti-cancer Drug, Cobimetinib, for Advanced-Stage Biliary Tract Cancer

Recurrent Gallbladder Carcinoma | Metastatic Gallbladder Carcinoma | Stage IV Gallbladder Cancer AJCC v8 | Stage IV Intrahepatic Cholangiocarcinoma AJCC v8 | Stage IV Distal Bile Duct Cancer AJCC v8 | Metastatic Intrahepatic Cholangiocarcinoma | Recurrent Intrahepatic Cholangiocarcinoma | Metastatic... and other conditions

United States
Assistance Publique - Hôpitaux de Paris
University of Paris 5 - Rene Descartes

Completed

Trial of Psychoeducational and Hypnosis Interventions on the Fatigue Associated With PBC in Women (CBP-HOPE)

Liver Cirrhosis, Biliary

France
Assistance Publique - Hôpitaux de Paris

Completed

Phase 3 Study of Bezafibrate in Combination With Ursodeoxycholic Acid in Primary Biliary Cirrhosis (BEZURSO)

PBC

France
University of California, Davis
National Cancer Institute (NCI)

Recruiting

Patient-Derived Xenografts to Reduce Cancer Health Disparities

Gastric Carcinoma | Lung Carcinoma | Malignant Neoplasm | Bladder Carcinoma | Liver and Intrahepatic Bile Duct Carcinoma

United States
SAMEY
Axonal-Biostatem

Unknown

A Post-Authorisation Non-Interventional Observational of Patients in France With Primary Biliary Cholangitis Treated With Obeticholic Acid in Real Life (OCARELIFE)

Primary Biliary Cholangitis

France
Institut Paoli-Calmettes

Completed

Intra-ductal Confocal Endomicroscopy for Characterization of Pancreas and Bile Duct Tumor (EMID)

Bile Duct Diseases | Pancreas Neoplasms

France, Monaco
Dr. Falk Pharma GmbH

Terminated

Ursodeoxycholic Acid Plus Budesonide Versus Ursodeoxycholic Acid Alone in Primary Biliary Cirrhosis (PBC)

Primary Biliary Cirrhosis

France, Germany
University Hospital, Bordeaux

Completed

Acoustic Radiation Force Impulse Imaging (ARFI) : a New Technique to Assess Liver Elasticity (NARFI)

Liver Cirrhosis | Liver Fibrosis | Cardiac Failure | Viral Hepatitis | Liver Tumour | Biliary Cholestasis.

France
National Cancer Institute (NCI)

Completed

Trametinib or Combination Chemotherapy in Treating Patients With Refractory or Advanced Biliary or Gallbladder Cancer or That Cannot Be Removed by Surgery (S1310)

Hilar Cholangiocarcinoma | Advanced Adult Hepatocellular Carcinoma | Localized Non-Resectable Adult Liver Carcinoma | Recurrent Adult Liver Carcinoma | Recurrent Gallbladder Carcinoma | Stage IV Distal Bile Duct Cancer | Unresectable Extrahepatic Bile Duct Carcinoma | Stage II Gallbladder Cancer | Stage... and other conditions

United States
University Hospital, Tours

Completed

ABCB4 Gene Mutations in Intrahepatic Cholestasis of Pregnancy and Controls

Intrahepatic Cholestasis of Pregnancy

France
Institut National de la Santé Et de la Recherche...

Recruiting

Molecular Characterization for Understanding Biliary Atresia (CAVB)

Biliary Atresia

France
Central Hospital, Nancy, France

Completed

Colonization of Bile Ducts and Postoperative Infectious Complications of Pancreaticoduodenectomies

Sepsis | Pancreatic Cancer | Fistula | Bile Duct Cancer | Delayed Gastric Emptying | Post-Op Complication | Duodenal Cancer | Post-Op Infection | Bile Duct; Obliteration | Fistula, Biliary

France
Mauna Kea Technologies
Emissary International LLC; Cellvizio Inc.

Completed

A Registry of Patients Undergoing Cellvizio Endomicroscopy and Endoscopic Retrograde Cholangiopancreatography(ERCP) Imaging Procedures for Diagnosing Pancreatic and Bile Duct Cancers

Pancreatic Cancer | Bile Duct Cancer

United States, Germany, France
Intercept Pharmaceuticals

Terminated

Study of INT 747 in Combination With URSO in Patients With Primay Biliary Cirrhosis (PBC)

Liver Cirrhosis, Biliary

United States, Spain, Canada, United Kingdom, France, Germany, Austria, Netherlands
Centre Hospitalier Universitaire de Saint Etienne
Federation Francophone de Cancerologie Digestive

Completed

Safety and Efficacy of Modified Folfirinox Versus Gemcis in Bile Duct Tumours (AMEBICA)

Bile Duct Cancer

France
Intercept Pharmaceuticals

Completed

Study of INT-747 as Monotherapy in Participants With Primary Biliary Cirrhosis (PBC)

Liver Cirrhosis, Biliary

United States, France, Germany, Spain, United Kingdom, Canada, Austria
Institut Paoli-Calmettes

Recruiting

Evaluation of the Use of a Biodegradable Endoprothesis in the Prevention of Post-Endoscopic Retrograde CholoangioPancreatography Pancreatitis (ARCHIMEDE)

Sphincter of Oddi Dysfunction | Biliary Stricture | Obstructive Jaundice

France
Bordeaux Colorectal Institute Academy

Recruiting

Low Stable Pressure Pneumoperitoneum in Colorectal Surgery (CROSS STUDY) (CROSS)

Colorectal Surgery | Benign or Malignant Rectal or Colon Tumors

France, Switzerland, Argentina, Belgium, Germany, Italy, Netherlands, Spain, United Kingdom
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S0202 Gemcitabine and Capecitabine for Unresectable Locally Advanced Metastatic Gallbladder Cancer or Cholangiocarcinoma

Gallbladder Cancer | Extrahepatic Bile Duct Cancer

United States
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S0809: Capecitabine, Gemcitabine, and RT in Patients w/Cholangiocarcinoma of the Gallbladder or Bile Duct

Gallbladder Cancer | Extrahepatic Bile Duct Cancer

United States
Mauna Kea Technologies

Completed

pCLE For the Diagnosis Of Cancer in Unknown Bile Duct Stricture (FOCUS)

Cholangiocarcinoma | Bile Duct Inflammation

United States, France, Italy
National Cancer Institute (NCI)

Completed

Sorafenib Tosylate and Erlotinib Hydrochloride in Treating Patients With Locally Advanced, Unresectable, or Metastatic Gallbladder Cancer or Cholangiocarcinoma

Hilar Cholangiocarcinoma | Recurrent Gallbladder Carcinoma | Unresectable Extrahepatic Bile Duct Carcinoma | Unresectable Gallbladder Carcinoma | Gallbladder Adenocarcinoma | Recurrent Extrahepatic Bile Duct Carcinoma | Extrahepatic Bile Duct Adenocarcinoma | Gallbladder Adenocarcinoma With Squamous... and other conditions

United States
GERCOR - Multidisciplinary Oncology Cooperative...

Unknown

Chemotherapy in Treating Patients With Locally Advanced or Metastatic Cancer of the Pancreas or Bile Duct

Pancreatic Cancer | Extrahepatic Bile Duct Cancer

France, Luxembourg
Calliditas Therapeutics Suisse SA

Active, not recruiting

A Trial of Setanaxib in Patients With Primary Biliary Cholangitis (PBC) and Liver Stiffness (TRANSFORM)

Primary Biliary Cholangitis | Liver Stiffness

United States, Spain, France, Australia, Israel, Canada, Switzerland, Italy, New Zealand, Germany, Poland, Greece, United Kingdom, Belgium, Austria, Czechia, Hungary, Sweden
Assistance Publique - Hôpitaux de Paris

Completed

Non Invasive Study of the Hepatic Fibrosis in Paediatrics by the Method of Study of Pediatric Hepatic Fibrosis (PEDISCAN)

Cirrhosis | Cystic Fibrosis | Portal Hypertension | Liver Fibrosis | Cholestasis of Parenteral Nutrition

France
Intercept Pharmaceuticals

Active, not recruiting

Study of OCA in Combination With BZF Evaluating Efficacy, Safety, and Tolerability in Participants With PBC

Primary Biliary Cholangitis

Netherlands, United Kingdom, Korea, Republic of, Germany, Australia, Estonia, Belgium, France, Czechia, Croatia, Greece, Hungary, Israel, Lithuania, Norway, Poland, Spain
Enanta Pharmaceuticals, Inc
Pharmaceutical Research Associates; Triangle Biostatistics

Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of EDP-305 in Subjects With Primary Biliary Cholangitis

Primary Biliary Cholangitis

United States, Spain, Canada, Australia, United Kingdom, Germany, Netherlands, Belgium, Austria, France
Albireo

Active, not recruiting

Long Term Safety & Efficacy Study Evaluating The Effect of A4250 in Children With PFIC

Progressive Familial Intrahepatic Cholestasis

United States, Spain, Netherlands, United Kingdom, Turkey, Canada, Italy, Germany, France, Israel, Australia, Belgium, Poland, Saudi Arabia, Sweden
Intercept Pharmaceuticals

Completed

Phase 3 Study of Obeticholic Acid in Patients With Primary Biliary Cirrhosis (POISE)

Primary Biliary Cirrhosis

United States, Spain, United Kingdom, Austria, Netherlands, Australia, Italy, Germany, Poland, Sweden, France, Canada, Belgium
Gilead Sciences

Terminated

Study to Evaluate the Safety, Tolerability, and Efficacy of Cilofexor in Adults With Primary Biliary Cholangitis Without Cirrhosis (PBC-Phase 2)

Primary Biliary Cholangitis

United States, Canada, Austria, United Kingdom
COUR Pharmaceutical Development Company, Inc.

Active, not recruiting

Study to Evaluate the Safety, Tolerability, PDs, and Efficacy of CNP-104 in Subjects With Primary Biliary Cholangitis

Primary Biliary Cholangitis

United States
Zydus Therapeutics Inc.

Not yet recruiting

Open-Label Extension Study of Saroglitazar Magnesium in Participants With Primary Biliary Cholangitis

Primary Biliary Cholangitis

United States, Turkey, Argentina
CymaBay Therapeutics, Inc.

Completed

ENHANCE: Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and an Inadequate Response to or an Intolerance to Ursodeoxycholic Acid (UDCA)

Primary Biliary Cholangitis

United States, Spain, United Kingdom, Israel, France, Korea, Republic of, Australia, Italy, Hungary, Germany, Romania, Belgium, Canada, Greece, New Zealand, Austria, Serbia, Russian Federation, Argentina, Mexico, Netherlands, Chile, Polan...
Genfit

Completed

Study to Evaluate the Efficacy and Safety of Elafibranor in Patients With Primary Biliary Cholangitis (PBC) and Inadequate Response to Ursodeoxycholic Acid

Primary Biliary Cholangitis (PBC)

United States, United Kingdom, France, Germany, Spain
Intercept Pharmaceuticals

Terminated

Study of Obeticholic Acid (OCA) Evaluating Pharmacokinetics and Safety in Participants With Primary Biliary Cholangitis (PBC) and Hepatic Impairment

Liver Cirrhosis, Biliary

United States, Argentina, Spain, Belgium, Germany, Canada, Australia, Estonia, Brazil, Hungary, Italy, Lithuania
CymaBay Therapeutics, Inc.

Recruiting

Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis (AFFIRM)

Primary Biliary Cholangitis

United States, Korea, Republic of, Turkey
Mirum Pharmaceuticals, Inc.

Completed

Open Label Study to Evaluate Efficacy and Long Term Safety of LUM001 (Maralixibat) in the Treatment of Cholestatic Liver Disease in Patients With Progressive Familial Intrahepatic Cholestasis (INDIGO)

Progressive Familial Intrahepatic Cholestasis (PFIC)

United States, United Kingdom, Poland, France

Clinical Trials on Benign or Malignant Liver and Bile Duct Disease in France

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