Clinical Trials on Bone Diseases, Metabolic in Czechia

Total 5521 results

University Hospital Inselspital, Berne
Czech Technical University in Prague

Recruiting

SPEECH as Biomarker for Emotion, Movement and cOgnition in Parkinson's Disease (EMO-SPEECH-PD)

Parkinson Disease

Switzerland, Czechia
Novo Nordisk A/S

Completed

Observational Study on the Weight Effect of Insulin Detemir (Levemir®) in Type 2 Diabetics

Diabetes Mellitus, Type 2 | Diabetes

Czech Republic
Institute for Clinical and Experimental Medicine

Completed

Postprandial Insulin Secretion, Oxidative Stress and Gastrointestinal Peptides in Patients With Type 2 Diabetes Versus Healthy Subjects

Type 2 Diabetes | Postprandial Oxidative Stress

Czech Republic
General University Hospital, Prague

Recruiting

SpiroGym App-Aided Cough Rehabilitation (ESApp PD)

Parkinson Disease | mHealth | Voluntary Peak Cough Strength

Czechia
University Hospital Hradec Kralove

Recruiting

Role of Brain Specific Biomarkers in Hydrocephalus

Brain Damage | Hydrocephalus, Normal Pressure | Biochemical Lesions Head Region

Czechia
University Hospital Inselspital, Berne
Czech Technical University in Prague

Recruiting

REducing SPEECH-related Side-effects of Deep Brain Stimulation in Parkinson's Disease Via Automated Speech Analysis (RESPEECH-PD)

Parkinson Disease

Switzerland, Czechia
Institute for Clinical and Experimental Medicine
Motol University Hospital; General University Hospital in Prague

Completed

Stimulation TcPO2 Test in the PAD Diagnosis in Diabetic Foot (stimTcPO2)

Peripheral Arterial Disease

Czechia
BioMarin Pharmaceutical
ICON plc

Completed

A Multicenter, Multinational, Observational Morquio A Registry Study (MARS) (MARS)

Mucopolysaccharidosis IV Type A | Morquio A Syndrome | MPS IVA

United States, United Kingdom, Australia, Taiwan, Belgium, Malaysia, Austria, Canada, Portugal, France, Ireland, Czechia, Denmark, Italy, Netherlands, Poland, Puerto Rico
General University Hospital, Prague
Czech Academy of Sciences

Recruiting

The Effect of Gluten-free Diet on Parkinsonism (GFREEPARK)

Parkinson Disease | Multiple System Atrophy | Non-celiac Gluten Sensitivity

Czechia
Amgen

Completed

Evaluation of New or Worsening Lens Opacifications in Men With Non-metastatic Prostate Cancer Receiving Denosumab for Bone Loss

Cancer | Cataract | Prostate Cancer | Osteoporosis | Osteopenia | Low Bone Mineral Density

United States, Canada, Czechia, Poland, Russian Federation, Slovakia, Hungary, South Africa, Greece, Bulgaria, France, Ukraine, Australia, Latvia, India, Slovenia, New Zealand, Mexico
Institute for Clinical and Experimental Medicine

Completed

Endothelial Function in Patients With Type 2 Diabetes Versus Healthy Subjects (EndoPat)

Insulin Resistance | Type 2 Diabetes

Czech Republic
DePuy International

Terminated

A Single Centre Study to Assess the Long-term Performance of the Pinnacle™ Cup With a Ceramic-on-ceramic Bearing in Primary Total Hip Replacement

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Traumatic Femoral Fractures | Nonunion of Femoral Fractures

Czech Republic
University Hospital, Motol
Faculty Hospital Kralovske Vinohrady; Czech Academy of Sciences

Unknown

The Effect of Gluten-free Diet on New Onset Type 1 Diabetes (T1D)

Type 1 Diabetes

Czech Republic
University Hospital Hradec Kralove

Unknown

Joint Application of Human Insulin and Rapid Insulin Analogue in Control of Postprandial Glycemia (CPIT)

Diabetes Mellitus, Type 1

Czech Republic
Institute for Clinical and Experimental Medicine
Ministry of Health, Czech Republic

Completed

Effect of Angiotensin Receptor Blockade on Insulin Resistance and Adipose Tissue Cytokines in Type 2 Diabetes

Insulin Resistance | Type 2 Diabetes

Czech Republic
European Society for Blood and Marrow Transplantation
Novartis

Completed

Non Interventional Study on Iron Toxicity After First Allo-transplant in MDS/CMML

MDS | CMML

Germany, Belgium, Czechia
Carebot s.r.o.

Completed

Retrospective Study of Carebot AI CXR Performance in Preclinical Practice

Pneumonia | Lung Diseases | Pneumothorax | Lung Cancer | Cardiomegaly | Artificial Intelligence | Pulmonary Edema | Pleural Effusion | Atelectasis | Consolidation | Hilar Calcification | Fracture Rib

Czechia
Institute for Clinical and Experimental Medicine
Ministry of Health, Czech Republic

Unknown

Polyclonal Anti-T-Lymphocyte Globulin (ATG) in Type 1 Diabetes

Diabetes Mellitus, Type 1

Czech Republic
Faculty Hospital Kralovske Vinohrady

Recruiting

Novel Inhibitors of Lipolysis in the Treatment of Lipid a Glucose Metabolism in Obstructive Sleep Apnea Syndrome (NORRIS)

Obesity | Obstructive Sleep Apnea

Czechia
Charles University, Czech Republic

Active, not recruiting

Illusory Movements in Patients With Burns (Immobile)

Burns | Catabolic State | Illusions, Kinesthetic

Czechia
Amgen

Terminated

Open-label Extension of Study 20130173 of Denosumab in Children and Young Adults With Osteogenesis Imperfecta

Osteogenesis Imperfecta (OI)

Canada, Czechia, Spain, United Kingdom, United States, Italy, Hungary, Australia, Belgium, France, Germany, Poland
Amgen

Completed

Evolocumab Compared to LDL-C Apheresis in Patients Receiving LDL-C Apheresis Prior to Study Enrollment

Hypercholesterolemia

France, Germany, United States, Czechia, Italy, Australia, Spain, United Kingdom
Mgr. Eliška Vrátná
Vladimíra Fejfarová, MD, PhD; prof. Ing. Václav Bunc, CSc

Unknown

Musculoskeletal Changes After Physiotherapeutic Intervention in Podiatric Subjects (BIONEDIAN)

Prevention of Diabetic Foot

Czechia
Nitinotes Surgical Ltd.

Active, not recruiting

Evaluation of Health Improvement in Obese Patients With Obesity-related Comorbidities Followed by EndoZip Procedure (CL00010)

Obesity

Italy, Czechia
Nutricia Research

Recruiting

Effect of Omega 3 Enriched Oral Nutritional Supplement on Nutritional Status of CRC and NSCLC Patients (OMENS)

Malnutrition | Oncology

Ireland, Belgium, Czechia
BioMarin Pharmaceutical

Completed

Kuvan® in Phenylketonuria Patients Less Than 4 Years Old (SPARK)

Phenylketonuria

Italy, Turkey, United Kingdom, Germany, Netherlands, Slovakia, Austria, Belgium, Czechia
Aptabio Therapeutics, Inc.

Completed

Safety, Tolerability and Renal Effects of APX-115 in Subjects With Type 2 Diabetes and Nephropathy

Diabetes Mellitus, Type 2 | Diabetic Nephropathies | Nephropathy, Diabetic

Bulgaria, Czechia, Hungary, Serbia
University Hospital Ostrava
University of Ostrava; Vítkovice Hospital Ostrava, Czech Republic

Completed

Aspiration Therapy for Obese Adolescents

Obesity, Morbid

Czechia
University Hospital Ostrava

Active, not recruiting

Bariatric Endoscopy and NAFLD

Obesity | NAFLD | Liver Steatosis | Liver Fibrosis

Czechia
GlaxoSmithKline

Completed

Evaluation of Immune Memory to Twinrix or Comparator by Challenge Dose Administration 4 Years After Primary Vaccination

Hepatitis B | Hepatitis A

Belgium, Czechia
Shire

Completed

Safety and Efficacy Study of Several Replagal Dosing Regimens on Cardiac Function in Adults With Fabry Disease

Fabry Disease

United States, United Kingdom, Australia, Czechia, Finland, Paraguay, Poland, Slovenia
GlaxoSmithKline

Completed

Evaluation of Antibody Persistence & Immune Memory in Subjects Vaccinated During Adolescence With Twinrix™

Hepatitis B | Hepatitis A

Belgium, Czechia
Rocket Pharmaceuticals Inc.

Completed

Natural History of Danon Disease

Danon Disease

Ireland, Czechia, France, Italy, Spain
St. Anne's University Hospital Brno, Czech Republic

Completed

Relationship Between Normal-weight Central Obesity and Obstructive Sleep Apnea

Sleep Disorder | Body Fat Distribution

Czechia
Dompé Farmaceutici S.p.A

Completed

Study to Assess Efficacy & Safety of Reparixin in Pancreatic Islet Transplantation (REP0211)

Islet Transplantation in Diabetes Mellitus Type 1

United States, Czechia, Italy, Sweden, United Kingdom
Nemocnice Břeclav, p.o.

Unknown

Roux-en-Y Gastric Bypass (RYGB) Versus Omega-Loop Gastric Bypass (OLGB) Safety and Efficacy Short-term Study (ROSESS)

Diabetes Mellitus, Type 2 | Obesity, Severe

Czech Republic
Genzyme, a Sanofi Company

Completed

A Study of the Safety and Efficacy of Fabrazyme in Patients With Fabry Disease

Fabry Disease

Czech Republic, Estonia, Poland, Slovakia
University Hospital Ostrava

Recruiting

Prevention of Onset and Transition to an Advanced Form of Diabetic Retinopathy in Children

Diabetic Retinopathy

Czechia
University Hospital Ostrava
University of Ostrava

Completed

Bariatric Surgery and Fatty Liver Disease

Hypertension | Diabetes | Morbid Obesity

Czechia
Contipro Pharma a.s.

Completed

First-in-man Study of Adult Patients Suffered From Alveolar Osteitis Treated Using Stomatological Tamponade Contipro

Alveolar Osteitis

Czechia
Bayer

Completed

Bonefos and the Consumption of Analgesics (BICAM)

Bone Neoplasms

Czech Republic
Protalix
Chiesi Farmaceutici S.p.A.

Completed

Study of the Safety and Efficacy of PRX-102 Compared to Agalsidase Beta on Renal Function (BALANCE)

Fabry Disease

United States, Netherlands, Hungary, United Kingdom, Czechia, Norway, Slovenia, Spain, Finland, France, Italy, Switzerland
Novartis Pharmaceuticals

Completed

A Two-part Single- and Repeat-dose Study of CSJ137 in Anemic Chronic Hemodialysis Patients

Anemia, Iron-Deficiency

Czechia, Israel, United States, United Kingdom
Value Outcomes Ltd.
Matuzalem.com-cz, s.r.o.

Completed

Vaginal Ovule With Flavonoid Tea Extract for the Correction of Imbalance in the Vaginal Environment (MAT072017)

Vaginosis, Bacterial | Vaginal Flora Imbalance

Czechia
Gelesis, Inc.

Completed

Effect of GSP3 on Body Weight in Overweight and Obese Subjects (FLOW)

Obesity | Overweight

Italy, Denmark, Czechia
University Hospital Freiburg

Completed

Assessing Immune Function in Young Patients With Cytopenia That Did Not Respond to Treatment

Myelodysplastic Syndromes | Fanconi Anemia | Dyskeratosis Congenita | Pearson Marrow-pancreas Syndrome | Shwachman-diamond Syndrome

Spain, Germany, Switzerland, Austria, Netherlands, Italy, Czech Republic, Belgium, Denmark, Ireland
Masaryk University

Active, not recruiting

Efficacy and Safety of TKIs' Withdrawal After a Two-step Dose Reduction in Patients With Chronic Myeloid Leukemia (HALF)

Chronic Myeloid Leukemia, Chronic Phase | Withdrawal;Drug

Czechia
Poznan University of Physical Education
National Science Centre, Poland; Faculty of Physical Education and Sport at... and other collaborators

Recruiting

The Impact of Exercise / Stress Stimuli on HMB Supplementation Efficacy

Supplementation | Sport | Sports Nutrition | Sports Dietetics | Protein Kinases | Aerobic Capacity | Fat Free Mass

Czechia, Poland
Genzyme, a Sanofi Company

Completed

Alglucosidase Alfa Pompe Safety Sub-Registry

Pompe Disease

Belgium, United States, Czechia, Germany, Italy, Taiwan
Faculty Hospital Kralovske Vinohrady

Completed

Fatty Acid Metabolism in Obstructive Sleep Apnea (FAMOSA) (FAMOSA)

Obstructive Sleep Apnea | Continuous Positive Airway Pressure | Fatty Acid Metabolism

Czechia

Clinical Trials on Bone Diseases, Metabolic in Czechia

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