Clinical Trials on Brachial Plexus; Injury, Newborn in Ireland

Total 109 results

Belfast Health and Social Care Trust
Queen's University, Belfast; NHS Blood and Transplant; Northern Ireland Clinical...

Recruiting

Repair of Acute Respiratory Distress Syndrome by Stromal Cell Administration (REALIST) (REALIST)

Acute Respiratory Distress Syndrome

United Kingdom
Women and Infants Hospital of Rhode Island

Completed

Study of Nasal Ventilation In Preterm Infants To Decrease Time on The Respirator

Bronchopulmonary Dysplasia

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Personalized Mechanical Ventilation Guided by UltraSound in Patients With Acute Respiratory Distress Syndrome

ARDS, Human | Mechanical Ventilation | Lung Ultrasound

Denmark, Italy, Netherlands, Belgium, Greece, Ireland, Poland
Academisch Medisch Centrum - Universiteit van Amsterdam...
University of Sao Paulo; National University of Ireland, Galway, Ireland; Carlos...

Active, not recruiting

PRactice of VENTilation in Patients With ARDS Due to COVID-19 vs Pneumonia (PRoVENT-COP)

COVID-19 | Pneumonia | Acute Respiratory Distress Syndrome | Mechanical Ventilation Complication

Netherlands, Argentina, Brazil, Ireland, Spain
University College Hospital Galway

Recruiting

Nebulised Heparin to Reduce COVID-19 Induced Acute Lung Injury (CHARTER-Irl)

Covid19 | ARDS, Human | Ventilation Perfusion Mismatch | Lung Injury, Acute

Ireland
University College Dublin

Completed

Routine Or Selective Application of a Face Mask for Preterm Infants at Birth: the ROSA Trial (ROSA)

Infant, Premature, Diseases | Respiratory Distress Syndrome, Newborn | Resuscitation | Positive-Pressure Respiration | Continuous Positive Airway Pressure

Ireland
Queen's University, Belfast
Innovate UK; Northern Ireland Clinical Trials Unit

Active, not recruiting

Clinical Evaluation of a Point of Care (POC) Assay to Identify Phenotypes in the Acute Respiratory Distress Syndrome (PHIND)

Acute Respiratory Distress Syndrome (ARDS)

United Kingdom, Ireland
Children's Hospital of Philadelphia
Rhode Island Hospital; Children's Miracle Network; American Respiratory Care...

Recruiting

NAVA vs. CMV Crossover in Severe BPD

Bronchopulmonary Dysplasia | Mechanical Ventilation | Neurally Adjusted Ventilatory Assist

United States
Queen's University, Belfast

Unknown

The Study of ELEctronic Cigarette Toxicity in a Human Model in Vivo Model of Inflammation and Vascular Dysfunction (SELECT)

Acute Lung Injury

United Kingdom
Australian and New Zealand Intensive Care Research...

Terminated

A Multi-centre Trial of an Open Lung Strategy Including Permissive Hypercapnia, Alveolar Recruitment and Low Airway Pressure in Patients With Acute Respiratory Distress Syndrome (PHARLAP)

Acute Respiratory Distress Syndrome

Australia, Ireland, United Kingdom, New Zealand, Saudi Arabia
University of Limerick

Unknown

Steps Ahead: Optimising Physical Activity and Health in Adults With Cystic Fibrosis

Cystic Fibrosis

Ireland
University College Cork
Assistance Publique - Hôpitaux de Paris; KU Leuven; University of Washington; Queen... and other collaborators

Completed

Cystic Fibrosis Microbiome-determined Antibiotic Therapy Trial in Exacerbations: Results Stratified (CFMATTERS)

Cystic Fibrosis

Ireland
NICHD Neonatal Research Network
National Center for Research Resources (NCRR)

Completed

Vitamin A Supplementation for Extremely-Low-Birth-Weight Infants (Vitamin A)

Sepsis | Respiratory Distress Syndrome, Newborn | Bronchopulmonary Dysplasia | Respiration, Artificial | Infant, Small for Gestational Age | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn

United States
Veru Inc.

Completed

COVID-19 Treatment of Severe Acute Respiratory Syndrome With Veru-111

Respiratory Distress Syndrome, Adult

United States
NICHD Neonatal Research Network
National Center for Research Resources (NCRR)

Completed

Dexamethasone Therapy in VLBW Infants at Risk of CLD (Dexamethasone)

Bronchopulmonary Dysplasia | Infant, Small for Gestational Age | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn

United States
Eli Lilly and Company

Completed

A Phase II Study to Determine the Efficacy and Safety of Sivelestat in Subjects With Acute Lung Injury

Acute Lung Injury | Respiratory Distress Syndrome, Adult

United States, Belgium, Spain, Canada, Australia, New Zealand
NICHD Neonatal Research Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

The Budesonide in Babies (BiB) Trial (BiB)

Respiratory Distress Syndrome | Bronchopulmonary Dysplasia (BPD) | Prematurity; Extreme | Neonatal

United States
NICHD Neonatal Research Network
National Center for Research Resources (NCRR)

Completed

Benchmarking Initiative to Reduce Bronchopulmonary Dysplasia (Benchmarking)

Bronchopulmonary Dysplasia (BPD) | Infant, Small for Gestational Age | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn

United States
University College Cork

Not yet recruiting

Assessment of Diastolic Function During the Transitional Period and Infancy Using Serial Echocardiography (DiFuSE)

Gestational Diabetes | Neonatal Encephalopathy | Diastolic Dysfunction | Trisomy 21 | Transient Tachypnea of the Newborn | Small for Gestational Age at Delivery

Ireland
NICHD Neonatal Research Network
National Center for Research Resources (NCRR)

Terminated

Minimal Breathing Support and Early Steroids to Prevent Chronic Lung Disease in Extremely Premature Infants (SAVE) (SAVE)

Respiratory Distress Syndrome | Bronchopulmonary Dysplasia | Infant, Small for Gestational Age | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn

United States
NICHD Neonatal Research Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Active, not recruiting

Hydrocortisone for BPD

Bronchopulmonary Dysplasia | Infant, Very Low Birth Weight | Infant, Small for Gestational Age | Infant, Premature | Infant, Newborn

United States
Pulmatrix Inc.
Celerion

Completed

A Safety and Tolerability Study OF PUR118 In Subjects With Cystic Fibrosis

Cystic Fibrosis

United Kingdom
McMaster University
Canadian Institutes of Health Research (CIHR)

Completed

Nasal Intermittent Positive Pressure Ventilation in Premature Infants (NIPPV) (NIPPV)

Respiratory Insufficiency of Prematurity

United States, Singapore, United Kingdom, Canada, Ireland, Qatar, Austria, Belgium, Netherlands, Sweden
NICHD Neonatal Research Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Physiologic Definition of Bronchopulmonary Dysplasia (PhysiologicDef)

Bronchopulmonary Dysplasia (BPD) | Infant, Small for Gestational Age | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn

United States
AlgiPharma AS

Completed

A Cross-over Study of OligoG in Subjects With Cystic Fibrosis. Fibrosis (OligoG)

Cystic Fibrosis

United Kingdom, Ireland
EyePoint Pharmaceuticals, Inc.
Medical Technology Enterprise Consortium (MTEC)

Terminated

Evaluation of the Safety and Efficacy of Razuprotafib in Hospitalized Subjects With Coronavirus Disease 2019 (RESCUE)

COVID-19 | Acute Respiratory Distress Syndrome (ARDS)

United States
Children's Health Ireland
Queen's University, Belfast; Cystic Fibrosis Foundation; European Cystic Fibrosis...

Active, not recruiting

COVID-19 Antibody Responses in Cystic Fibrosis (CAR-CF)

COVID-19 | Cystic Fibrosis

Ireland
University of Rhode Island
National Institute of Nursing Research (NINR); Thrasher Research Fund

Completed

Effects of Delayed Cord Clamping in Very Low Birth Weight Infants

Necrotizing Enterocolitis | Intraventricular Hemorrhage | Bronchopulmonary Dysplasia | Motor Skills Disorders | Late Onset Neonatal Sepsis

United States
NICHD Neonatal Research Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Single-Dose Intravenous Inositol Pharmacokinetics in Preterm Infants (INS-1)

Retinopathy of Prematurity | Bronchopulmonary Dysplasia (BPD) | Infant, Small for Gestational Age | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn

United States
Celtaxsys, Inc.
Celerion

Completed

Phase 1 Study Assessing the Safety and Tolerability of CTX-4430 in Cystic Fibrosis Patients

Cystic Fibrosis

United Kingdom
NICHD Neonatal Research Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Multi-dose Pharmacokinetics and Dose Ranging of Inositol in Premature Infants (INS-2) (INS-2)

Retinopathy of Prematurity | Bronchopulmonary Dysplasia (BPD) | Infant, Small for Gestational Age | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn

United States
St. James's Hospital, Ireland

Completed

Neoadjuvant Therapy for Esophageal Cancer and Cardiopulmonary Physiology

Pneumonia | Adenocarcinoma | Respiratory Failure | Esophageal Cancer | Pulmonary Fibrosis | Surgery | Chemotherapy Effect | Radiation Toxicity | Squamous Cell Carcinoma | Radiation Pneumonitis | Radiation Fibrosis

Ireland
Women and Infants Hospital of Rhode Island

Unknown

CPAP vs.Unsynchronized NIPPV at Equal Mean Airway Pressure (NICA)

Respiratory Distress Syndrome | Apnea of Prematurity | Prematurity

United States
Ionis Pharmaceuticals, Inc.

Completed

A Phase 1/2a Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Doses of IONIS-ENaCRx in Healthy Volunteers and Patients With Cystic Fibrosis

Cystic Fibrosis | Healthy Subjects

United Kingdom, Germany
University of Colorado, Denver

Completed

Identifying the Most Accurate Method for Predicting the Safe Depth of Orally Placed Neonatal Endotracheal Tubes (ETT).

Ventilator Adverse Event | Infant Showing No Response to Resuscitation | Apparent Life Threatening Event in Newborn and Infant

United States, Ireland
NICHD Neonatal Research Network
National Center for Research Resources (NCRR)

Terminated

Early Surfactant to Reduce Use of Mechanical Breathing in Low Birth Weight Infants (Surfactant 2)

Respiratory Insufficiency | Respiratory Distress Syndrome | Infant, Newborn

United States
Royal College of Surgeons, Ireland
The Hospital for Sick Children; Imperial College London; Erasmus Medical Center; University College Dublin and other collaborators

Active, not recruiting

Real World Clinical Outcomes With Novel Modulator Therapy Combinations in People With CF (RECOVER) (RECOVER)

Cystic Fibrosis | Adherence, Medication | Cystic Fibrosis Gastrointestinal Disease | Cystic Fibrosis in Children | Cystic Fibrosis Liver Disease

United Kingdom, Ireland
Pharmaxis

Completed

Long Term Administration of Inhaled Dry Powder Mannitol In Cystic Fibrosis - A Safety and Efficacy Study

Cystic Fibrosis

Ireland, United Kingdom, Australia
NICHD Neonatal Research Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Active, not recruiting

Transfusion of Prematures Trial (TOP)

Infant, Newborn, Diseases | Anemia | Infant, Extremely Low Birth Weight | Bronchopulmonary Dysplasia (BPD) | Infant, Small for Gestational Age

United States
NICHD Neonatal Research Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Surfactant Positive Airway Pressure and Pulse Oximetry Trial (SUPPORT)

Infant, Newborn, Diseases | Premature Birth | Retinopathy of Prematurity | Bronchopulmonary Dysplasia | Other Preterm Infants | Infant, Small for Gestational Age

United States
Windtree Therapeutics

Completed

The Safety and Efficacy of Lucinactant for Inhalation in Premature Neonates 26 to 32 Weeks Gestational Age

Respiratory Distress Syndrome

United States, Canada, Colombia, Hungary, Chile, Ireland, Netherlands, Poland
Galapagos NV

Completed

Study of GLPG1837 in Subjects With Cystic Fibrosis (G551D Mutation) (SAPHIRA1)

Cystic Fibrosis

United Kingdom, Australia, Ireland, Germany, Czech Republic
AstraZeneca

Completed

A Phase II , Placebo-controlled Study to Assess Efficacy of 28 Day Oral AZD9668 in Patients With Cystic Fibrosis (INCA)

Cystic Fibrosis

Sweden, Russian Federation, United Kingdom, Poland, Denmark, Germany
NICHD Neonatal Research Network
National Center for Research Resources (NCRR)

Completed

Persistent Pulmonary Hypertension of the Newborn (PPHN) Observational Study (PPHN)

Persistent Fetal Circulation Syndrome | Infant, Small for Gestational Age | Persistent Pulmonary Hypertension of Newborn | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn

United States
Bayer
Merck Sharp & Dohme LLC

Terminated

Early Signs of Efficacy Study With Riociguat in Adult Homozygous Delta F508 Cystic Fibrosis Patients

Cystic Fibrosis

Germany, United States, France, Canada, Belgium, Netherlands, United Kingdom
Galapagos NV

Completed

A Study to Evaluate GLPG2222 in Ivacaftor-treated Subjects With Cystic Fibrosis

Cystic Fibrosis

Ireland, United Kingdom, Belgium, Australia, Czechia, Germany
Queen's University, Belfast
Cystic Fibrosis Foundation

Recruiting

COVID-19 Antibody Responses In Cystic Fibrosis (CAR-CF)

Covid19 | Cystic Fibrosis

United Kingdom
OHB Neonatology Ltd.

Active, not recruiting

A Clinical Efficacy and Safety Study of OHB-607 in Preventing Chronic Lung Disease in Extremely Premature Infants

Intraventricular Hemorrhage | Bronchopulmonary Dysplasia | Chronic Lung Disease of Prematurity | Retinopathy of Prematurity (ROP)

United States, United Kingdom, Italy, France, Germany, Netherlands, Finland, Japan, Portugal, Canada, Ireland, Spain, Sweden
Windtree Therapeutics

Terminated

Trial To Assess The Safety And Tolerability Of Lucinactant For Inhalation In Preterm Neonates 26 to 28 Weeks PMA

Respiratory Distress Syndrome

Canada, United States, Chile, Poland
Synspira, Inc.

Terminated

A Study of the Safety and Tolerability of Inhaled SNSP113 in Healthy Subjects and Subjects With Stable Cystic Fibrosis

Lung Diseases | Cystic Fibrosis | Pulmonary Disease | Antibiotic Resistant Infection | Respiratory Tract Disease | Cystic Fibrosis Pulmonary Exacerbation | Lung Inflammation | Burkholderia Infections | Lung Infection | Multi-antibiotic Resistance | Pulmonary Inflammation | Lung Infection Pseudomonal | Cystic Fibrosis... and other conditions

United Kingdom

Clinical Trials on Brachial Plexus; Injury, Newborn in Ireland

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