Clinical Trials on Brain Glioma in United States

Total 13774 results

Theodore S. Johnson
Augusta University

Recruiting

Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer

Glioblastoma | Ependymoma | Medulloblastoma | Primary Brain Tumor

United States
Emory University
CURE Childhood Cancer, Inc.; Peach Bowl LegACy Fund

Completed

WP1066 in Children With Refractory and Progressive or Recurrent Malignant Brain Tumors

Brain Tumor | Medulloblastoma | Brain Metastases

United States
Susan Chang
GE Healthcare; Sigma-Aldrich; Phillips-Medisize

Recruiting

Serial MR Imaging and MR Spectroscopic Imaging for the Characterization of Lower Grade Glioma

Recurrent WHO Grade III Glioma | WHO Grade III Glioma | WHO Grade II Glioma | Recurrent World Health Organization (WHO) Grade II Glioma

United States
University of California, Davis
National Cancer Institute (NCI); NovoCure Ltd.

Withdrawn

NovoTTF-100A With Bevacizumab and Carmustine in Treating Patients With Glioblastoma Multiforme in First Relapse

Recurrent Adult Brain Neoplasm | Adult Brain Glioblastoma

United States
University of California, San Francisco

Terminated

Safety Study of Aminolevulinic Acid (ALA) to Enhance Visualization and Resection of Tumors of the Brain (ALA)

Glioma

United States
Michael Prados
National Cancer Institute (NCI); Genentech, Inc.

Terminated

Erlotinib in Treating Patients With Recurrent Glioblastoma Multiforme or Gliosarcoma

Adult Brain Tumors

United States
Jonsson Comprehensive Cancer Center
National Institutes of Health (NIH)

Completed

Vaccine Therapy in Treating Patients With Malignant Glioma

Brain and Central Nervous System Tumors

United States
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Completed

Ferumoxytol in Improving MR Imaging in Patients With High-Grade Brain Tumors or Cerebral Metastases

Malignant Glioma | Metastatic Malignant Neoplasm in the Brain | Central Nervous System Lymphoma

United States
University of Alabama at Birmingham
National Cancer Institute (NCI); Gateway for Cancer Research

Recruiting

Trial of C134 in Patients With Recurrent GBM (C134-HSV-1)

Glioblastoma Multiforme of Brain | Anaplastic Astrocytoma of Brain | Gliosarcoma of Brain

United States
Massachusetts General Hospital

Completed

Monitoring Anti-angiogenic Therapy in Brain Tumors by Advanced MRI

Glioblastoma

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Completed

Tumor Tissue Analysis in Patients Receiving Imatinib Mesylate for Malignant Glioma

Brain and Central Nervous System Tumors

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Immunotoxin Therapy Before and After Surgery in Treating Patients With Recurrent Malignant Glioma

Brain and Central Nervous System Tumors

United States
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI)

Completed

ATN-161 and Carboplatin in Treating Patients With Recurrent Malignant Glioma

Brain and Central Nervous System Tumors

United States
Jonsson Comprehensive Cancer Center
United States Department of Defense

Recruiting

Simultaneous Multinuclear Metabolic MRI in Newly Diagnosed or Recurrent Glioma

Glioma | Malignant Glioma | Recurrent Malignant Glioma | Recurrent Glioma

United States
NYU Langone Health
Genentech, Inc.; Atlantic Health System

Terminated

Temodar (Temozolomide), Bevacizumab, Lithium and Radiation for High Grade Glioma

Brain Cancer

United States
Burzynski Research Institute

Completed

Antineoplaston Therapy in Treating Patients With Newly-diagnosed Glioblastoma Multiforme

Glioblastoma Multiforme of Brain

United States
Emory University
CURE Childhood Cancer, Inc.

Completed

Pegylated Interferon ALFA-2b in Children With Juvenile Pilocytic Astrocytomas and Optic Pathway Gliomas

Juvenile Pilocytic Astrocytomas | Optic Pathway Gliomas

United States
Wake Forest University Health Sciences
NovoCure Ltd.

Terminated

A Phase II Study of Optune (NovoTTF) in Combination With Bevacizumab (BEV) and Temozolomide (TMZ) in Patients With Newly Diagnosed Unresectable Glioblastoma (GBM)

Cancer of Brain and Nervous System

United States
Bradmer Pharmaceuticals Inc.

Unknown

Neuradiab® Combined With Bevacizumab (Avastin) Therapy in Patients With Recurrent Glioblastoma Multiforme

Brain Tumors

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Bafetinib in Treating Patients With Recurrent High-Grade Glioma or Brain Metastases

Adult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Recurrent Adult Brain Tumor | Tumors Metastatic to Brain | Adult Anaplastic Oligoastrocytoma

United States
University of California, San Francisco
Novartis Pharmaceuticals; Pacific Pediatric Neuro-Oncology Consortium; The Pediatric...

Active, not recruiting

PNOC 001: Phase II Study of Everolimus for Recurrent or Progressive Low-grade Gliomas in Children

Pediatric Recurrent Progressive Low-grade Gliomas | Pediatric Progressive Low-grade Gliomas

United States
Massachusetts General Hospital
GlaxoSmithKline

Recruiting

Niraparib In Recurrent IDH 1/2 Gliomas

Recurrent Glioma | Low-grade Glioma | Glioma, Malignant | IDH2 Gene Mutation | IDH1 Mutation

United States
Henry Friedman

Completed

Pilot Study of Bone Marrow/Stem Cells in Grade IV Malignant Glioma

Grade IV Malignant Glioma

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Imatinib Mesylate in Treating Patients With Recurrent Brain Tumor

Adult Anaplastic Oligodendroglioma | Adult Mixed Glioma | Adult Oligodendroglioma | Recurrent Adult Brain Neoplasm

United States
Karen D. Wright MD
Medical University of South Carolina; Johns Hopkins University; Washington University... and other collaborators

Terminated

Molecularly Determined Treatment of Diffuse Intrinsic Pontine Gliomas (DIPG)

Diffuse Intrinsic Pontine Glioma

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Early Integration of Palliative Care Using the BEACON PROQOL in Patients With High Grade Glioma and Their Caregivers

Glioblastoma | Malignant Glioma | WHO Grade III Glioma

United States
National Cancer Institute (NCI)

Completed

Temsirolimus and Perifosine in Treating Patients With Recurrent or Progressive Malignant Glioma

Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Diffuse Astrocytoma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Adult Oligodendroglioma | Recurrent Adult Brain Neoplasm

United States
Northwestern University
National Cancer Institute (NCI); BrainUp Inc

Not yet recruiting

Triapine in Combination With Temozolomide for the Treatment of Patients With Recurrent Glioblastoma

Recurrent WHO Grade 2 Glioma | Recurrent Glioblastoma, IDH-Wildtype | Recurrent WHO Grade 3 Glioma | Recurrent WHO Grade 4 Glioma

United States
Duke University
Genentech, Inc.; Schering-Plough

Completed

Avastin in Combination With Radiation (XRT) & Temozolomide, Followed by Avastin, Temozolomide and Irinotecan for Glioblastoma (GBM) and Gliosarcomas

Glioblastoma | Brain Tumor | Gliosarcoma

United States
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients With Malignant Glioma

Brain and Central Nervous System Tumors

United States
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Gimatecan in Treating Patients With Recurrent or Progressive Primary Malignant Glioma

Brain and Central Nervous System Tumors

United States
Duke University
National Cancer Institute (NCI)

Completed

Irinotecan Plus Carmustine in Treating Patients With Recurrent Primary Malignant Glioma

Brain and Central Nervous System Tumors

United States
Case Comprehensive Cancer Center

Not yet recruiting

Magnetic Resonance Fingerprinting Guided Extended Resection in Glioblastomas

Glioblastoma | Brain Tumor

United States
University of Alabama at Birmingham

Completed

A Phase I Study of ABT 510 for Newly Diagnosed Glioblastoma Multiforme

Brain Tumor

United States
Memorial Sloan Kettering Cancer Center

Completed

Assessing 11C-Choline (11C-CH) PET to Distinguish True Tumor Progression From Pseudoprogression in High-grade Gliomas

Brain Cancer

United States
University of Alabama at Birmingham

Completed

A Pilot Study to Determine Nutrition Status in Glioblastoma Multiforme Patients (BEAM)

Brain Cancer

United States
Pharmacyclics LLC.

Completed

A Study of Motexafin Gadolinium and Temozolomide for the Treatment of Malignant Gliomas

Glioma | Glioblastoma | Astrocytoma | Brain Neoplasm | Oligodendroglioma

United States
Nicholas Butowski
Celldex Therapeutics

Active, not recruiting

A Study of Varlilumab and IMA950 Vaccine Plus Poly-ICLC in Patients With WHO Grade II Low-Grade Glioma (LGG)

Glioma | Malignant Glioma | Oligodendroglioma | Astrocytoma, Grade II | Glioma, Astrocytic | Oligoastrocytoma, Mixed

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Following Radiation Therapy in Treating Patients With Malignant Glioma

Brain and Central Nervous System Tumors

United States
OncoSynergy, Inc.
Infuseon Therapeutics, Inc.

Terminated

Convection-enhanced Delivery of OS2966 for Patients With High-grade Glioma Undergoing a Surgical Resection

Glioblastoma | Glioblastoma Multiforme | High Grade Glioma | Anaplastic Astrocytoma | Glioma, Malignant

United States
Providence Health & Services
University of California, San Francisco; NovoCure Ltd.

Terminated

Tumor Treating Fields With Chemoradiation in Newly Diagnosed GBM

Glioblastoma | Brain Tumor | Glioblastoma Multiforme | Cancer of Brain

United States
National Cancer Institute (NCI)

Recruiting

Study of Zotiraciclib for Recurrent High-Grade Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations

Cancer | Brain Tumor

United States
M.D. Anderson Cancer Center

Completed

Standard Dose Bevacizumab Versus Low Dose Bevacizumab Plus Lomustine (CCNU) for Recurrent Glioblastoma Multiforme (GBM)

Glioblastoma | Brain Cancer

United States
University of Wisconsin, Madison
National Cancer Institute (NCI)

Completed

PET/CT Imaging of Malignant Brain Tumors With 124I-NM404

Glioblastoma | Brain Metastases

United States
University of Florida
National Institutes of Health (NIH)

Completed

Study of the Safety and Efficacy of Dichloroacetate (DCA) in Glioblastoma and Other Recurrent Brain Tumors

Glioblastoma | Brain Tumor

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...

Recruiting

Intensity-Modulated Stereotactic Radiation Therapy in Treating Patients With Grade II-IV Glioma

Glioblastoma | WHO Grade III Glioma | WHO Grade II Glioma

United States
Seattle Children's Hospital

Recruiting

Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors

Glioma | Ependymoma | Medulloblastoma, Childhood | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma | Central Nervous System Tumor | Germ Cell Tumor | Atypical Teratoid/Rhabdoid Tumor | Primitive Neuroectodermal Tumor | Choroid Plexus Carcinoma | Pineoblastoma, Childhood

United States
Washington University School of Medicine
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

BIRN (Biomedical Informatics Research Network) Resources Facilitate the Personalization of Malignant Brain Tumor (CONDR)

Brain Neoplasm | GLIOBLASTOMA MULTIFORME

United States
H. Lee Moffitt Cancer Center and Research Institute
Olympus Corporation

Completed

Novel Exoscope System for 5-ALA Fluorescence-Guided Surgery for Gliomas

Glioma | Brain Tumor

United States
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Completed

MRI Study With Ferumoxytol in Assessing Early Response in Patients With Glioblastoma Multiforme Receiving Temozolomide and Radiation Therapy

Adult Brain Glioblastoma

United States

Clinical Trials on Brain Glioma in United States

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