Clinical Trials on Brain Gliomas

Total 32563 results

Sidney Kimmel Cancer Center at Thomas Jefferson...
Millennium Pharmaceuticals, Inc.

Completed

Alisertib and Fractionated Stereotactic Radiosurgery in Treating Patients With Recurrent High Grade Gliomas

Adult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma | Adult Diffuse Astrocytoma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Adult Oligodendroglioma | Adult Pilocytic Astrocytoma | Adult Pineal Gland Astrocytoma | Recurrent... and other conditions

United States
Memorial Sloan Kettering Cancer Center

Recruiting

Magnetic Resonance (MR) Imaging to Determine High Risk Areas in Patients With Malignant Gliomas and to Design Potential Radiation Plans and to Examine Metabolite Changes in Gliomas and Other Solid Tumors

Glioma | Brain Cancer

United States
GT Medical Technologies, Inc.

Recruiting

Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)

Brain Tumor | Brain Tumor, Recurrent | Brain Tumor, Primary | Brain Tumor - Metastatic | Brain Tumor, Adult: Glioblastoma | Brain Tumor, Adult Meningioma

United States
Incyte Corporation

Active, not recruiting

Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Previously Treated Glioblastoma or Other Primary Central Nervous System Tumors Harboring Activating FGFR1-3 Alterations (FIGHT-209)

Glioblastoma | Adult-type Diffuse Gliomas

United States, Spain, Italy, United Kingdom, Germany, Japan, France, Netherlands, Denmark
University of Alabama at Birmingham
National Cancer Institute (NCI); Gateway for Cancer Research

Recruiting

Trial of C134 in Patients With Recurrent GBM (C134-HSV-1)

Glioblastoma Multiforme of Brain | Anaplastic Astrocytoma of Brain | Gliosarcoma of Brain

United States
Massachusetts General Hospital

Completed

Monitoring Anti-angiogenic Therapy in Brain Tumors by Advanced MRI

Glioblastoma

United States
Bristol-Myers Squibb
Ono Pharmaceutical Co. Ltd

Completed

An Investigational Immuno-therapy Study of Nivolumab Compared to Temozolomide, Each Given With Radiation Therapy, for Newly-diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer) (CheckMate 498)

Brain Cancer

United States, Canada, Belgium, Spain, Australia, Netherlands, United Kingdom, Denmark, Norway, Japan, Sweden, France, Poland, Austria, Germany, Israel, Italy, Russian Federation, Switzerland
University of California, San Francisco

Terminated

Safety Study of Aminolevulinic Acid (ALA) to Enhance Visualization and Resection of Tumors of the Brain (ALA)

Glioma

United States
NewLink Genetics Corporation

Completed

Study of IDO Inhibitor and Temozolomide for Adult Patients With Primary Malignant Brain Tumors

Glioma | Glioblastoma Multiforme | Gliosarcoma | Malignant Brain Tumor

United States
Washington University School of Medicine
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

BIRN (Biomedical Informatics Research Network) Resources Facilitate the Personalization of Malignant Brain Tumor (CONDR)

Brain Neoplasm | GLIOBLASTOMA MULTIFORME

United States
Assistance Publique - Hôpitaux de Paris
Roche Pharma AG

Completed

Temozolomide Plus Bevacizumab in Supratentorial Glioblastoma in 70 Years and Older Patients With an Impaired Functional Status (ATAG)

Glioblastoma Multiforme | Primary Brain Tumor

France
Assistance Publique - Hôpitaux de Paris

Completed

Radiotherapy for Malignant Astrocytomas in the Elderly

Glioblastoma Multiforme | Anaplastic Astrocytoma | Primary Brain Tumor

France
National Cancer Institute (NCI)

Completed

VEGF Trap in Treating Patients With Recurrent Malignant Gliomas That Did Not Respond to Temozolomide

Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
National Cancer Institute (NCI)

Terminated

RO4929097and Bevacizumab in Treating Patients With Progressive or Recurrent Malignant Glioma

Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
National Cancer Institute (NCI)

Completed

Sorafenib in Treating Patients With Recurrent or Progressive Malignant Glioma

Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
National Cancer Institute (NCI)

Completed

AZD2171 in Treating Young Patients With Recurrent, Progressive, or Refractory Primary CNS Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Childhood Atypical Teratoid/Rhabdoid Tumor | Childhood Grade I Meningioma | Childhood Grade II Meningioma | Childhood Grade III Meningioma | Childhood Infratentorial Ependymoma | Childhood Supratentorial Ependymoma | Recurrent Childhood... and other conditions

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); Roswell Park Cancer Institute; American Lebanese...

Recruiting

A Pilot Study of SurVaxM in Children Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine Glioma

Glioblastoma Multiforme | Ependymoma | Medulloblastoma | Anaplastic Astrocytoma | Anaplastic Ependymoma | Anaplastic Oligodendroglioma | Diffuse Intrinsic Pontine Glioma | High-grade Astrocytoma NOS

United States, Canada
National Health Research Institutes, Taiwan

Recruiting

A Taiwanese Oncogenetic Panel and Integrated Clinical Data Registry Study for Diffuse Glioma

Primary Malignant Brain Tumors

Taiwan
University of Maryland, Baltimore
Keep Punching Foundation

Recruiting

LITT Followed by Hypofractionated RT for Newly Diagnosed Gliomas (GCC 20138)

Glioma | Glioblastoma | Brain Tumor

United States
Memorial Sloan Kettering Cancer Center
Weill Medical College of Cornell University

Active, not recruiting

Coping With Glioblastoma: A Study of Communication Between Physicians, Patients, and Caregivers

Glioblastoma | Brain Cancer

United States
The Leeds Teaching Hospitals NHS Trust

Unknown

Multi-parametric MRI/Fluorine-18 Fluciclovine PET-CT in Glioblastoma

Tumor, Brain

United Kingdom
Beijing Tiantan Hospital
Duke University

Unknown

Combination of Immunization and Radiotherapy for Malignant Gliomas (InSituVac1) (InSituVac1)

Glioblastoma | High Grade Glioma | Glioma, Malignant | Glioma of Brainstem

China
Imperial College London

Recruiting

Use of Non-invasive Optical Analysis in Neurosurgery

Glioma | Meningioma | Brain Metastases | Schwannoma | Brain Tumour

United Kingdom
Monteris Medical

Completed

Monteris AutoLITT™ FIM Safety Trial for Recurrent/Progressive Brain Tumors

Brain Cancer | Brain Tumor | Glioblastoma Multiforme | Brain Neoplasm | Recurrent Glioblastoma Multiforme | Brain Tumor, Recurrent

United States
University of Alabama at Birmingham

Completed

A Phase I Study of ABT 510 for Newly Diagnosed Glioblastoma Multiforme

Brain Tumor

United States
Memorial Sloan Kettering Cancer Center

Completed

Assessing 11C-Choline (11C-CH) PET to Distinguish True Tumor Progression From Pseudoprogression in High-grade Gliomas

Brain Cancer

United States
University of Alabama at Birmingham

Completed

A Pilot Study to Determine Nutrition Status in Glioblastoma Multiforme Patients (BEAM)

Brain Cancer

United States
Pharmacyclics LLC.

Completed

A Study of Motexafin Gadolinium and Temozolomide for the Treatment of Malignant Gliomas

Glioma | Glioblastoma | Astrocytoma | Brain Neoplasm | Oligodendroglioma

United States
John Sampson
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Vaccine Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme (ACTIVATe)

Malignant Neoplasms of Brain

United States
Duke University
Genentech, Inc.; Schering-Plough

Completed

Avastin in Combination With Radiation (XRT) & Temozolomide, Followed by Avastin, Temozolomide and Irinotecan for Glioblastoma (GBM) and Gliosarcomas

Glioblastoma | Brain Tumor | Gliosarcoma

United States
Henan Provincial People's Hospital

Not yet recruiting

Sintilimab (One Anti-PD-1 Antibody) Plus Low-dose Bevacizumab for ctDNAlevel- Relapse and Clinical-relapse Astrocytoma

Astrocytoma of Brain

China
Nova Scotia Health Authority
Canadian Cancer Society (CCS)

Enrolling by invitation

The Impact of Resistance ExerciSe on Muscle Mass in GlioblaSToma Survivors (RESIST)

Brain Cancer | Glioblastoma Multiforme of Brain

Canada
Memorial Sloan Kettering Cancer Center
Johns Hopkins University; M.D. Anderson Cancer Center; University of Colorado... and other collaborators

Completed

External Beam Radiation Therapy and Cetuximab Followed by Irinotecan and Cetuximab for Children and Young Adults With Newly Diagnosed Diffuse Pontine Tumors and High-Grade Astrocytomas

Brain Cancer

United States, Canada
Cedars-Sinai Medical Center

Terminated

Pilot Study of Vardenafil and Carboplatin in Patients With Gliomas and Brain Metastases (LevitraCarbo)

Glioma | Brain Neoplasms | Brain Metastasis

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Children With Progressive Brain Tumors

Brain Tumors | Central Nervous System Tumors

United States, Canada, Australia, Switzerland, Netherlands, New Zealand
Jona Hattangadi-Gluth

Recruiting

Longitudinal Prospective Study of Neurocognition & Neuroimaging in Primary BT Patients

Glioma | Meningioma | Primary Brain Tumor | Schwannoma

United States
Attikon Hospital

Recruiting

A Ketogenic Diet as a Complementary Treatment on Patients With High-grade Gliomas and Brain Metastases

Cancer | Brain

Greece
Dartmouth-Hitchcock Medical Center

Recruiting

Evaluating the Expression Levels of MicroRNA-10b in Patients With Gliomas

Glioblastoma | Astrocytoma | Brain Cancer | Anaplastic Oligoastrocytoma | Oligoastrocytoma | Anaplastic Astrocytoma | Oligodendroglioma | Brain Tumors | Anaplastic Oligodendroglioma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

FDG PET Imaging in Diagnosing Patients With Glioblastoma

Brain Glioblastoma

United States
University of California, San Francisco
BeiGene USA, Inc.; Pacific Pediatric Neuro-Oncology Consortium

Recruiting

BGB-290 and Temozolomide in Treating Isocitrate Dehydrogenase (IDH)1/2-Mutant Grade I-IV Gliomas (PNOC017)

Glioblastoma | Malignant Glioma | Recurrent Glioblastoma | Recurrent WHO Grade III Glioma | WHO Grade III Glioma | IDH2 Gene Mutation | IDH1 Gene Mutation | Low Grade Glioma | Recurrent WHO Grade II Glioma | WHO Grade II Glioma

United States
National Cancer Institute (NCI)

Completed

Temsirolimus and Perifosine in Treating Patients With Recurrent or Progressive Malignant Glioma

Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Diffuse Astrocytoma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Adult Oligodendroglioma | Recurrent Adult Brain Neoplasm

United States
Actuate Therapeutics Inc.

Recruiting

9-ING-41 in Pediatric Patients With Refractory Malignancies.

Neuroblastoma | Pediatric Cancer | Diffuse Intrinsic Pontine Glioma | Pediatric Brain Tumor | Refractory Cancer | Refractory Neoplasm | Refractory Tumor | Cancer Pediatric | Neuroblastoma Recurrent | Pediatric Lymphoma | Pediatric Meningioma

United States
Center Trials & Treatment

No longer available

Expanded Access for Pembrolizumab (MK-3475)

Glioblastoma Multiforme | Melanoma (Skin) | Melanoma Recurrent | Glioma of Brain | Glioblastoma by Gene Expression Profile

Hong Kong, Belarus, Tajikistan, Uzbekistan
Jasper Gerritsen
University Medical Center Groningen; University Hospital, Ghent; Medical Center... and other collaborators

Recruiting

The SAFE-Trial: Awake Craniotomy Versus Surgery Under General Anesthesia for Glioblastoma Patients. (SAFE)

Glioblastoma | Brain Neoplasms | Brain Cancer | Brain Tumor | Glioblastoma Multiforme | Astrocytoma, Grade IV | Glioblastoma Multiforme of Brain

Netherlands, Belgium
National Cancer Institute (NCI)

Completed

Pomalidomide in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors

Neurofibromatosis Type 1 | Recurrent Primary Central Nervous System Neoplasm | Refractory Primary Central Nervous System Neoplasm | Recurrent Childhood Brain Stem Glioma | Recurrent Childhood Visual Pathway Glioma

United States
Michigan State University
Sparrow Health System

Active, not recruiting

Pilot Study of a Metabolic Nutritional Therapy for the Management of Primary Brain Tumors (Ketones)

Glioblastoma

United States
University of California, San Francisco
Tilburg University

Terminated

Feasibility And Efficacy Of An iPad-Based Cognitive Rehabilitation Program In Brain Tumor Patients

Glioma

United States
University of Miami

Completed

Metabolic Tumor Volumes in Radiation Treatment of Primary Brain Tumors

Brain Tumor | Glioblastoma Multiforme

United States
John Sampson
National Cancer Institute (NCI)

Completed

Chemotherapy, Radiation Therapy, and Vaccine Therapy With Basiliximab in Treating Patients With Glioblastoma Multiforme That Has Been Removed by Surgery (ZAP IT)

Malignant Neoplasms of Brain

United States
TransMolecular

Completed

Safety and Tolerability Study of 131I-TM-601 to Treat Adult Patients With Recurrent Glioma.

Glioma | Brain Neoplasm

United States

Clinical Trials on Brain Gliomas

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